Details for: SERPINB9
Gene ID: 5272
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: SERPINB9
Ensembl ID: ENSG00000170542
Description: serpin family B member 9
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 27.08rCSI 39.23%PRS 56.4
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CSI 26.26rCSI 40.11%PRS 57.96
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CSI 18.86rCSI 28.46%PRS 42.39
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CSI 15.6rCSI 21.27%PRS 21.39
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CSI 14.89rCSI 18.35%PRS 65.95
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CSI 14.88rCSI 10.39%PRS 42.36
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CSI 13.49rCSI 20.84%PRS 38.79
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CSI 13.42rCSI 16.61%PRS 36.86
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CSI 12.56rCSI 15.17%PRS 47.84
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CSI 11.79rCSI 38.24%PRS 44.12
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CSI 10.35rCSI 23.24%PRS 61.22
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CSI 10.3rCSI 47.6%PRS 63.5
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CSI 8.79rCSI 11.96%PRS 53.26
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CSI 8.39rCSI 14.35%PRS 61.39
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CSI 7.98rCSI 16.47%PRS 47.8
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CSI 7.79rCSI 17.79%PRS 34.91
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CSI 7.19rCSI 6.6%PRS 47.65
-
CSI 6.85rCSI 8.61%PRS 53.88
-
CSI 6.72rCSI 12.14%PRS 63.81
-
CSI 6.46rCSI 5.96%PRS 41.76
-
CSI 6.03rCSI 7.89%PRS 53.55
-
CSI 5.91rCSI 7.36%PRS 25.14
-
CSI 5.64rCSI 10.87%PRS 70.3
-
CSI 5.6rCSI 4.71%PRS 57.58
-
CSI 5.43rCSI 3.66%PRS 50.18
-
CSI 5.2rCSI 11.44%PRS 44.51
-
CSI 5.08rCSI 9.63%PRS 74.83
-
CSI 4.87rCSI 6.05%PRS 43.32
-
CSI 4.63rCSI 3.71%PRS 61.85
-
CSI 4.52rCSI 21.16%PRS 60.61
-
CSI 4.36rCSI 8.31%PRS 57.24
-
CSI 4.34rCSI 7.51%PRS 32.26
-
CSI 4.16rCSI 10.41%PRS 71.57
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CSI 4.1rCSI 2.85%PRS 53
-
CSI 3.77rCSI 5.79%PRS 47.24
-
CSI 3.73rCSI 12.5%PRS 30.38
-
CSI 3.44rCSI 2.59%PRS 43.67
-
CSI 3.4rCSI 2.44%PRS 52.8
-
CSI 3.36rCSI 3.93%PRS 55.43
-
CSI 3.28rCSI 3.48%PRS 56.03
-
CSI 3.18rCSI 13.19%PRS 50.94
-
CSI 3.18rCSI 2.96%PRS 40.61
-
CSI 3.14rCSI 3.28%PRS 71.38
-
CSI 3.08rCSI 3.67%PRS 60.57
-
CSI 3.07rCSI 6.89%PRS 27.15
-
CSI 3.04rCSI 10.07%PRS 42.13
-
CSI 3.04rCSI 3.11%PRS 59.31
-
CSI 2.94rCSI 2.39%PRS 41.71
-
CSI 2.94rCSI 2.19%PRS 58.78
-
CSI 2.89rCSI 2.68%PRS 60.91
-
CSI 2.87rCSI 2.18%PRS 51.36
-
CSI 2.86rCSI 4.7%PRS 45.97
-
CSI 2.84rCSI 2.21%PRS 56.8
-
CSI 2.78rCSI 6.35%PRS 40.17
-
CSI 2.74rCSI 2.07%PRS 52.37
-
CSI 2.73rCSI 2.49%PRS 55.22
-
CSI 2.67rCSI 8.55%PRS 37.91
-
CSI 2.64rCSI 4.17%PRS 41.71
-
CSI 2.61rCSI 4.46%PRS 66.63
-
CSI 2.59rCSI 11.9%PRS 61.08
-
CSI 2.56rCSI 10.65%PRS 42.24
-
CSI 2.52rCSI 9.59%PRS 35.22
-
CSI 2.5rCSI 2.07%PRS 41.53
-
CSI 2.49rCSI 14.01%PRS 73.41
-
CSI 2.48rCSI 5.47%PRS 30.23
-
CSI 2.42rCSI 2.38%PRS 68.83
-
CSI 2.39rCSI 8.61%PRS 25.48
-
CSI 2.38rCSI 8.93%PRS 34.7
-
CSI 2.38rCSI 5.78%PRS 25.76
-
CSI 2.32rCSI 1.83%PRS 29.55
-
CSI 2.31rCSI 1.78%PRS 39.26
-
CSI 2.26rCSI 2.48%PRS 44.48
-
CSI 2.25rCSI 11.07%PRS 51.91
-
CSI 2.24rCSI 1.95%PRS 49.25
-
CSI 2.24rCSI 9.02%PRS 52.21
-
CSI 2.21rCSI 1.31%PRS 54.59
-
CSI 2.18rCSI 2.61%PRS 59.57
-
CSI 2.16rCSI 2.12%PRS 55.56
-
CSI 2.15rCSI 3.43%PRS 44.08
-
CSI 2.12rCSI 6.09%PRS 57.46
-
CSI 2.12rCSI 4.39%PRS 38.99
-
CSI 2.09rCSI 1.54%PRS 35.06
-
CSI 2.07rCSI 2.87%PRS 46.29
-
CSI 2.07rCSI 1.82%PRS 45.37
-
CSI 2.06rCSI 6.33%PRS 52.91
-
CSI 2.04rCSI 2.3%PRS 56.43
-
CSI 2.04rCSI 4.56%PRS 46.74
-
CSI 2.02rCSI 2.41%PRS 26.46
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CSI 1.99rCSI 2.03%PRS 53.02
-
CSI 1.98rCSI 3.54%PRS 39.28
-
CSI 1.97rCSI 6.15%PRS 29.68
-
CSI 1.92rCSI 2.94%PRS 49.42
-
CSI 1.92rCSI 1.85%PRS 32.09
-
CSI 1.91rCSI 1.5%PRS 46.8
-
CSI 1.87rCSI 7.26%PRS 60.55
-
CSI 1.7rCSI 1.63%PRS 41.29
-
CSI 1.69rCSI 5.29%PRS 27.63
-
CSI 1.67rCSI 2.7%PRS 50.19
-
CSI 1.58rCSI 6.87%PRS 56.54
-
CSI 1.45rCSI 3.74%PRS 71.85
-
CSI 0.3rCSI 1.4%PRS 52.8%
-
CSI 0.3rCSI 1.4%PRS 51.1%
-
CSI 0.3rCSI 7.1%PRS 68.7%
-
CSI 0.3rCSI 1.8%PRS 65.8%
-
CSI 0.4rCSI 8.7%PRS 35.3%
-
CSI 0.5rCSI 7.3%PRS 78.6%
-
CSI 0.5rCSI 6.9%PRS 33.9%
-
CSI 0.5rCSI 0.7%PRS 49.8%
-
CSI 0.5rCSI 2.0%PRS 27.4%
-
CSI 0.6rCSI 0.5%PRS 37.5%
-
CSI 0.6rCSI 2.7%PRS 39.3%
-
CSI 0.6rCSI 3.4%PRS 50.4%
-
CSI 0.8rCSI 0.9%PRS 37.9%
-
CSI 0.8rCSI 2.8%PRS 59.5%
-
CSI 0.9rCSI 5.2%PRS 27.8%
-
CSI 0.9rCSI 18.3%PRS 34.1%
-
CSI 0.9rCSI 1.7%PRS 25.6%
-
CSI 1.0rCSI 4.9%PRS 42.7%
-
CSI 1.1rCSI 2.3%PRS 61.9%
-
CSI 1.2rCSI 2.1%PRS 67.7%
-
CSI 1.2rCSI 4.0%PRS 73.1%
-
CSI 1.2rCSI 1.0%PRS 62.1%
-
CSI 1.3rCSI 2.5%PRS 58.4%
-
CSI 1.3rCSI 2.1%PRS 28.6%
-
CSI 1.4rCSI 2.6%PRS 50.2%
-
CSI 1.4rCSI 4.1%PRS 58.6%
-
CSI 1.5rCSI 3.7%PRS 71.9%
-
CSI 1.6rCSI 6.9%PRS 56.5%
-
CSI 1.7rCSI 2.7%PRS 50.2%
-
CSI 1.7rCSI 5.3%PRS 27.6%
-
CSI 1.7rCSI 1.6%PRS 41.3%
-
CSI 1.9rCSI 7.3%PRS 60.6%
-
CSI 1.9rCSI 1.5%PRS 46.8%
-
CSI 1.9rCSI 1.9%PRS 32.1%
-
CSI 1.9rCSI 2.9%PRS 49.4%
-
CSI 2.0rCSI 6.2%PRS 29.7%
-
CSI 2.0rCSI 3.5%PRS 39.3%
-
CSI 2.0rCSI 2.0%PRS 53.0%
-
CSI 2.0rCSI 2.4%PRS 26.5%
-
CSI 2.0rCSI 4.6%PRS 46.7%
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CSI 2.0rCSI 2.3%PRS 56.4%
-
CSI 2.1rCSI 6.3%PRS 52.9%
-
CSI 2.1rCSI 1.8%PRS 45.4%
-
CSI 2.1rCSI 2.9%PRS 46.3%
-
CSI 2.1rCSI 1.5%PRS 35.1%
-
CSI 2.1rCSI 4.4%PRS 39.0%
-
CSI 2.1rCSI 6.1%PRS 57.5%
-
CSI 2.2rCSI 3.4%PRS 44.1%
-
CSI 2.2rCSI 2.1%PRS 55.6%
-
CSI 2.2rCSI 2.6%PRS 59.6%
-
CSI 2.2rCSI 1.3%PRS 54.6%
-
CSI 2.2rCSI 9.0%PRS 52.2%
-
CSI 2.2rCSI 2.0%PRS 49.3%
-
CSI 2.3rCSI 11.1%PRS 51.9%
-
CSI 2.3rCSI 2.5%PRS 44.5%
-
CSI 2.3rCSI 1.8%PRS 39.3%
-
CSI 2.3rCSI 1.8%PRS 29.6%
-
CSI 2.4rCSI 5.8%PRS 25.8%
-
CSI 2.4rCSI 8.9%PRS 34.7%
-
CSI 2.4rCSI 8.6%PRS 25.5%
-
CSI 2.4rCSI 2.4%PRS 68.8%
-
CSI 2.5rCSI 5.5%PRS 30.2%
-
CSI 2.5rCSI 14.0%PRS 73.4%
-
CSI 2.5rCSI 2.1%PRS 41.5%
-
CSI 2.5rCSI 9.6%PRS 35.2%
-
CSI 2.6rCSI 10.7%PRS 42.2%
-
CSI 2.6rCSI 11.9%PRS 61.1%
-
CSI 2.6rCSI 4.5%PRS 66.6%
-
CSI 2.6rCSI 4.2%PRS 41.7%
-
CSI 2.7rCSI 8.6%PRS 37.9%
-
CSI 2.7rCSI 2.5%PRS 55.2%
-
CSI 2.7rCSI 2.1%PRS 52.4%
-
CSI 2.8rCSI 6.4%PRS 40.2%
-
CSI 2.8rCSI 2.2%PRS 56.8%
-
CSI 2.9rCSI 4.7%PRS 46.0%
-
CSI 2.9rCSI 2.2%PRS 51.4%
-
CSI 2.9rCSI 2.7%PRS 60.9%
-
CSI 2.9rCSI 2.2%PRS 58.8%
-
CSI 2.9rCSI 2.4%PRS 41.7%
-
CSI 3.0rCSI 3.1%PRS 59.3%
-
CSI 3.0rCSI 10.1%PRS 42.1%
-
CSI 3.1rCSI 6.9%PRS 27.2%
-
CSI 3.1rCSI 3.7%PRS 60.6%
-
CSI 3.1rCSI 3.3%PRS 71.4%
-
CSI 3.2rCSI 3.0%PRS 40.6%
-
CSI 3.2rCSI 13.2%PRS 50.9%
-
CSI 3.3rCSI 3.5%PRS 56.0%
-
CSI 3.4rCSI 3.9%PRS 55.4%
-
CSI 3.4rCSI 2.4%PRS 52.8%
-
CSI 3.4rCSI 2.6%PRS 43.7%
-
CSI 3.7rCSI 12.5%PRS 30.4%
-
CSI 3.8rCSI 5.8%PRS 47.2%
-
CSI 4.1rCSI 2.9%PRS 53.0%
-
CSI 4.2rCSI 10.4%PRS 71.6%
-
CSI 4.3rCSI 7.5%PRS 32.3%
-
CSI 4.4rCSI 8.3%PRS 57.2%
-
CSI 4.5rCSI 21.2%PRS 60.6%
-
CSI 4.6rCSI 3.7%PRS 61.9%
-
CSI 4.9rCSI 6.1%PRS 43.3%
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CSI 5.1rCSI 9.6%PRS 74.8%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 263231482
Symbol: SPB9_HUMAN
Name: Serpin B9
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8530382
Title: Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors.
PubMed ID: 8530382
PubMed ID: 8910377
Title: A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes.
PubMed ID: 8910377
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 376
- Mass: 42404
- Checksum: ECBA80869B939753
- Sequence:
METLSNASGT FAIRLLKILC QDNPSHNVFC SPVSISSALA MVLLGAKGNT ATQMAQALSL NTEEDIHRAF QSLLTEVNKA GTQYLLRTAN RLFGEKTCQF LSTFKESCLQ FYHAELKELS FIRAAEESRK HINTWVSKKT EGKIEELLPG SSIDAETRLV LVNAIYFKGK WNEPFDETYT REMPFKINQE EQRPVQMMYQ EATFKLAHVG EVRAQLLELP YARKELSLLV LLPDDGVELS TVEKSLTFEK LTAWTKPDCM KSTEVEVLLP KFKLQEDYDM ESVLRHLGIV DAFQQGKADL SAMSAERDLC LSKFVHKSFV EVNEEGTEAA AASSCFVVAE CCMESGPRFC ADHPFLFFIR HNRANSILFC GRFSSP