Details for: PLCB2

Gene ID: 5330

Symbol: PLCB2

Ensembl ID: ENSG00000137841

Description: phospholipase C beta 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 46.7388
    Cell Significance Index: -7.2700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 20.8166
    Cell Significance Index: -5.2800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 19.8889
    Cell Significance Index: -8.0800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 17.1078
    Cell Significance Index: -8.8000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 5.8802
    Cell Significance Index: -7.2500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 2.7586
    Cell Significance Index: -7.3900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 2.6860
    Cell Significance Index: -8.2500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.9032
    Cell Significance Index: -7.5100
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 1.7116
    Cell Significance Index: 11.3600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.4885
    Cell Significance Index: 283.2700
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 1.2939
    Cell Significance Index: 8.2600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0378
    Cell Significance Index: 102.6600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.6011
    Cell Significance Index: 11.1100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.4974
    Cell Significance Index: 13.3100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4765
    Cell Significance Index: 77.4900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4433
    Cell Significance Index: 48.2200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.3316
    Cell Significance Index: 9.7400
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 0.3248
    Cell Significance Index: 0.8700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.3187
    Cell Significance Index: 12.0700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.3059
    Cell Significance Index: 35.6500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2953
    Cell Significance Index: 13.0600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2741
    Cell Significance Index: 18.9600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2444
    Cell Significance Index: 5.3500
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.2006
    Cell Significance Index: 1.6300
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: 0.1614
    Cell Significance Index: 1.1600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1328
    Cell Significance Index: 8.5700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1191
    Cell Significance Index: 7.1500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0564
    Cell Significance Index: 11.3200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0345
    Cell Significance Index: 4.0700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0252
    Cell Significance Index: 9.0500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0128
    Cell Significance Index: 0.3700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0075
    Cell Significance Index: 0.3900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0009
    Cell Significance Index: -0.0400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0023
    Cell Significance Index: -0.0800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0029
    Cell Significance Index: -2.0100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0032
    Cell Significance Index: -0.0700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0036
    Cell Significance Index: -6.8000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0046
    Cell Significance Index: -8.4700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0055
    Cell Significance Index: -8.4700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0060
    Cell Significance Index: -0.1500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0063
    Cell Significance Index: -8.5500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0078
    Cell Significance Index: -4.2800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0091
    Cell Significance Index: -6.9200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0107
    Cell Significance Index: -7.9600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0118
    Cell Significance Index: -8.6600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0131
    Cell Significance Index: -8.3500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0142
    Cell Significance Index: -7.9800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0176
    Cell Significance Index: -7.7700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0179
    Cell Significance Index: -3.7800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0182
    Cell Significance Index: -8.2800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0196
    Cell Significance Index: -5.6300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0211
    Cell Significance Index: -2.1600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0285
    Cell Significance Index: -5.6500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0322
    Cell Significance Index: -4.4200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0339
    Cell Significance Index: -6.1100
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0390
    Cell Significance Index: -0.5700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0391
    Cell Significance Index: -1.0000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0420
    Cell Significance Index: -7.1800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0478
    Cell Significance Index: -6.1700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0531
    Cell Significance Index: -1.1300
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0538
    Cell Significance Index: -0.8100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0561
    Cell Significance Index: -8.1500
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.0583
    Cell Significance Index: -0.6200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0595
    Cell Significance Index: -7.3200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0599
    Cell Significance Index: -4.6000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0628
    Cell Significance Index: -0.9000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0668
    Cell Significance Index: -3.1400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0668
    Cell Significance Index: -7.6500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0695
    Cell Significance Index: -7.2400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0724
    Cell Significance Index: -9.2800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0831
    Cell Significance Index: -1.3900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0843
    Cell Significance Index: -4.3900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1017
    Cell Significance Index: -6.8400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1092
    Cell Significance Index: -6.7100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1104
    Cell Significance Index: -8.7400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1112
    Cell Significance Index: -8.2900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1145
    Cell Significance Index: -5.3400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1234
    Cell Significance Index: -3.4500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1244
    Cell Significance Index: -7.6300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1244
    Cell Significance Index: -3.5500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1253
    Cell Significance Index: -6.5800
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.1278
    Cell Significance Index: -1.6200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1356
    Cell Significance Index: -7.6100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1478
    Cell Significance Index: -4.8400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1495
    Cell Significance Index: -4.7600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1524
    Cell Significance Index: -5.3400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1605
    Cell Significance Index: -5.1400
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1667
    Cell Significance Index: -3.2600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1686
    Cell Significance Index: -4.3400
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.1748
    Cell Significance Index: -2.0600
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.1825
    Cell Significance Index: -1.8300
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.1892
    Cell Significance Index: -2.3900
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.1959
    Cell Significance Index: -2.7500
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1996
    Cell Significance Index: -3.3900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.2023
    Cell Significance Index: -1.6500
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.2039
    Cell Significance Index: -2.7100
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.2048
    Cell Significance Index: -3.5300
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.2054
    Cell Significance Index: -1.8100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2081
    Cell Significance Index: -7.6400
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.2097
    Cell Significance Index: -5.0800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Enzyme activity**: PLCB2 is a phospholipase C enzyme that hydrolyzes PIP2 into IP3 and DAG. 2. **Subcellular localization**: PLCB2 is primarily located in the cytosol, where it catalyzes the hydrolysis of PIP2. 3. **Cellular expression**: PLCB2 is widely expressed in various cell types, including immune cells, neurons, and epithelial cells. 4. **Regulation**: PLCB2 is regulated by G-protein coupled receptors (GPCRs) and other signaling pathways, which modulate its activity and expression. 5. **Function**: PLCB2 plays a crucial role in various cellular processes, including insulin secretion, calcium mobilization, and sensory perception. **Pathways and Functions** PLCB2 is involved in several signaling pathways, including: 1. **Insulin secretion**: PLCB2 is activated by G-protein coupled receptors (GPCRs) and modulates insulin secretion in pancreatic beta cells. 2. **Calcium mobilization**: PLCB2 hydrolyzes PIP2 to IP3, which binds to IP3 receptors and releases calcium ions into the cytosol. 3. **Sensory perception**: PLCB2 is involved in the detection of chemical stimuli involved in sensory perception of bitter taste, sweet taste, and umami (glutamate) taste. 4. **G-protein mediated events**: PLCB2 is activated by G-protein beta/gamma-subunit complexes, which modulate its activity and expression. 5. **Phosphatidylinositol-mediated signaling**: PLCB2 is involved in the synthesis of IP3 and IP4 in the cytosol, which play roles in various cellular processes. **Clinical Significance** PLCB2 has been implicated in various diseases and disorders, including: 1. **Diabetes**: Dysregulation of PLCB2 has been linked to insulin resistance and type 2 diabetes. 2. **Neurological disorders**: PLCB2 has been implicated in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 3. **Cancer**: PLCB2 has been shown to be overexpressed in certain types of cancer, including breast and lung cancer. 4. **Immune system disorders**: PLCB2 has been implicated in the regulation of immune responses and the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. In conclusion, PLCB2 is a multifunctional enzyme involved in various cellular processes, including signaling pathways, metabolism, and sensory perception. Its dysregulation has been implicated in various diseases and disorders, highlighting the importance of PLCB2 in human health and disease.

Genular Protein ID: 4047595621

Symbol: PLCB2_HUMAN

Name: Phosphoinositide phospholipase C-beta-2

UniProtKB Accession Codes:

Q00722 A8K6J2 B9EGH5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 4 CTD 1 ChEBI 15 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 4 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 5 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 14 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 9 RefSeq 3 Rhea 4 SABIO-RK 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 5 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1644792

Title: Cloning, sequencing, expression, and Gq-independent activation of phospholipase C-beta 2.

PubMed ID: 1644792

DOI: 10.1016/s0021-9258(18)41963-1

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9188725

Title: Phosphoinositide binding specificity among phospholipase C isozymes as determined by photo-cross-linking to novel substrate and product analogs.

PubMed ID: 9188725

DOI: 10.1021/bi9702288

PubMed ID: 23625927

Title: WDR26 functions as a scaffolding protein to promote Gbetagamma-mediated phospholipase C beta2 (PLCbeta2) activation in leukocytes.

PubMed ID: 23625927

DOI: 10.1074/jbc.m113.462564

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 17115053

Title: Crystal structure of Rac1 bound to its effector phospholipase C-beta2.

PubMed ID: 17115053

DOI: 10.1038/nsmb1175

Sequence Information:

  • Length: 1185
  • Mass: 134024
  • Checksum: A0397309D943672A
  • Sequence:
    • MSLLNPVLLP PKVKAYLSQG ERFIKWDDET TVASPVILRV DPKGYYLYWT YQSKEMEFLD 
ITSIRDTRFG KFAKMPKSQK LRDVFNMDFP DNSFLLKTLT VVSGPDMVDL TFHNFVSYKE 
NVGKAWAEDV LALVKHPLTA NASRSTFLDK ILVKLKMQLN SEGKIPVKNF FQMFPADRKR 
VEAALSACHL PKGKNDAINP EDFPEPVYKS FLMSLCPRPE IDEIFTSYHA KAKPYMTKEH 
LTKFINQKQR DSRLNSLLFP PARPDQVQGL IDKYEPSGIN AQRGQLSPEG MVWFLCGPEN 
SVLAQDKLLL HHDMTQPLNH YFINSSHNTY LTAGQFSGLS SAEMYRQVLL SGCRCVELDC 
WKGKPPDEEP IITHGFTMTT DIFFKEAIEA IAESAFKTSP YPIILSFENH VDSPRQQAKM 
AEYCRTIFGD MLLTEPLEKF PLKPGVPLPS PEDLRGKILI KNKKNQFSGP TSSSKDTGGE 
AEGSSPPSAP AGEGTVWAGE EGTELEEEEV EEEEEEESGN LDEEEIKKMQ SDEGTAGLEV 
TAYEEMSSLV NYIQPTKFVS FEFSAQKNRS YVISSFTELK AYDLLSKASV QFVDYNKRQM 
SRIYPKGTRM DSSNYMPQMF WNAGCQMVAL NFQTMDLPMQ QNMAVFEFNG QSGYLLKHEF 
MRRPDKQFNP FSVDRIDVVV ATTLSITVIS GQFLSERSVR TYVEVELFGL PGDPKRRYRT 
KLSPSTNSIN PVWKEEPFVF EKILMPELAS LRVAVMEEGN KFLGHRIIPI NALNSGYHHL 
CLHSESNMPL TMPALFIFLE MKDYIPGAWA DLTVALANPI KFFSAHDTKS VKLKEAMGGL 
PEKPFPLASP VASQVNGALA PTSNGSPAAR AGAREEAMKE AAEPRTASLE ELRELKGVVK 
LQRRHEKELR ELERRGARRW EELLQRGAAQ LAELGPPGVG GVGACKLGPG KGSRKKRSLP 
REESAGAAPG EGPEGVDGRV RELKDRLELE LLRQGEEQYE CVLKRKEQHV AEQISKMMEL 
AREKQAAELK ALKETSENDT KEMKKKLETK RLERIQGMTK VTTDKMAQER LKREINNSHI 
QEVVQVIKQM TENLERHQEK LEEKQAACLE QIREMEKQFQ KEALAEYEAR MKGLEAEVKE 
SVRACLRTCF PSEAKDKPER ACECPPELCE QDPLIAKADA QESRL

Genular Protein ID: 2882916010

Symbol: Q9BVT6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9BVT6

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 2 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 Pfam 4 Proteomes 2 ProteomicsDB 2 RefSeq 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

Sequence Information:

  • Length: 199
  • Mass: 22679
  • Checksum: 45F20F517544AA61
  • Sequence:
    • MSLLNPVLLP PKVKAYLSQG ERFIKWDDET TVASPVILRV DPKGYYLYWT YQSKEMEFLD 
ITSIRDTRFG KFAKMPKSQK LRDVFNMDFP DNSFLLKTLT VVSGPDMVDL TFHNFVSYKE 
NVGKAWAEDV LALVKHPLTA NASRSTFLDK ILVKLKMQLN SEGKIPVKNF FQMFPADRKR 
VEAALSACHL PKGKPGGAR

Genular Protein ID: 1482176460

Symbol: Q59F77_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59F77

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChEBI 15 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 5 Gene3D 4 InterPro 12 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 2 PRINTS 1 PROSITE 5 PeptideAtlas 1 Pfam 5 PharmGKB 1 RefSeq 3 Rhea 4 RuleBase 1 SAM 1 SMART 3 SUPFAM 4

Sequence Information:

  • Length: 901
  • Mass: 101751
  • Checksum: 8BFD658D0FA74529
  • Sequence:
    • QRGTLGTMSL LNPVLLPPKV KAYLSQGERF IKWDDETTVA SPVILRVDPK GYYLYWTYQS 
KEMEFLDITS IRDTRFGKFA KMPKSQKLRD VFNMDFPDNS FLLKTLTVVS GPDMVDLTFH 
NFVSYKENVG KAWAEDVLAL VKHPLTANAS RSTFLDKILV KLKMQLNSEG KIPVKNFFQM 
FPADRKRVEA ALSACHLPKG KNDAINPEDF PEPVYKSFLM SLCPRPEIDE IFTSYHAKAK 
PYMTKEHLTK FINQKQRDSR LNSLLFPPAR PDQVQGLIDK YEPSGINAQR GQLSPEGMVW 
FLCGPENSVL AQDKLLLHHD MTQPLNHYFI NSSHNTYLTA GQFSGLSSAE MYRQVLLSGC 
RCVELDCWKG KPPDEEPIIT HGFTMTTDIF FKEAIEAIAE SAFKTSPYPI ILSFENHVDS 
PRQQAKMAEY CRTIFGDMLL TEPLEKFPLK PGVPLPSPED LRGKILIKNK KNQFSGPTSS 
SKDTGGEAEG SSPPSAPAGE GTVWAGEEGT ELEEEEVEEE EEEESGNLDE EEIKKMQSDE 
GTAGLEVTAY EEMSSLVNYI QPTKFVSFEF SAQKNRSYVI SSFTELKAYD LLSKASVQFV 
DYNKRQMSRI YPKGTRMDSS NYMPQMFWNA GCQMVALNFQ TMDLPMQQNM AVFEFNGQSG 
YLLKHEFMRR PDKQFNPFSV DRIDVVVATT LSITVISGQF LSERSVRTYV EVELFGLPGD 
PKRRYRTKLS PSTNSINPVW KEEPFVFEKI LMPELASLRV AVMEEGNKFL GHRIIPINAL 
NSGYHHLCLH SESNMPLTMP ALFIFLEMKD YIPGAWADLT VALANPIKFF SAHDTKSVKL 
KEAMGGLPEK PFPLASPVAS QVNGALAPTS NGSPGMSFGP HTYWGHLHLC THRHFPLKNF 
T

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.