Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 318.2997
Cell Significance Index: -49.5100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 198.8619
Cell Significance Index: -50.4400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 103.6290
Cell Significance Index: -42.1000 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 44.1061
Cell Significance Index: -42.1100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 40.1555
Cell Significance Index: -49.5100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 18.7356
Cell Significance Index: -50.1900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 13.1957
Cell Significance Index: -28.8800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 12.7824
Cell Significance Index: -50.4400 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 4.4811
Cell Significance Index: 64.4500 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.8893
Cell Significance Index: 39.4200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.7889
Cell Significance Index: 77.9400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.7587
Cell Significance Index: 989.4900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.4959
Cell Significance Index: 500.6700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.8071
Cell Significance Index: 81.9100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.6898
Cell Significance Index: 63.9900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.4135
Cell Significance Index: 86.8800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.3617
Cell Significance Index: 60.2300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.3614
Cell Significance Index: 221.4300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.2926
Cell Significance Index: 256.5200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.2803
Cell Significance Index: 1156.0500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 1.1640
Cell Significance Index: 27.9200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.0800
Cell Significance Index: 72.6200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.0593
Cell Significance Index: 732.6200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.7184
Cell Significance Index: 78.1400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.6497
Cell Significance Index: 18.5400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.6369
Cell Significance Index: 15.9200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.6220
Cell Significance Index: 37.3400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.5691
Cell Significance Index: 66.3200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5585
Cell Significance Index: 68.6700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.5331
Cell Significance Index: 15.3600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5286
Cell Significance Index: 52.3000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.4946
Cell Significance Index: 314.1500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.4708
Cell Significance Index: 26.4200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3915
Cell Significance Index: 70.5800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3190
Cell Significance Index: 22.0600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2953
Cell Significance Index: 37.8600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.2590
Cell Significance Index: 9.1000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.2392
Cell Significance Index: 4.1000 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.1660
Cell Significance Index: 2.4900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.1611
Cell Significance Index: 4.1400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1283
Cell Significance Index: 9.8500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1272
Cell Significance Index: 239.4800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1208
Cell Significance Index: 54.8100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0820
Cell Significance Index: 14.0100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0755
Cell Significance Index: 14.3700 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.0679
Cell Significance Index: 0.4100 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0036
Cell Significance Index: -1.9600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0081
Cell Significance Index: -0.4200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0129
Cell Significance Index: -19.8400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0249
Cell Significance Index: -45.9500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0251
Cell Significance Index: -15.6800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0265
Cell Significance Index: -3.8500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0334
Cell Significance Index: -24.7600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0408
Cell Significance Index: -55.5200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0451
Cell Significance Index: -33.1000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0451
Cell Significance Index: -34.1300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0519
Cell Significance Index: -29.2900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0576
Cell Significance Index: -25.4600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1345
Cell Significance Index: -28.3300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1549
Cell Significance Index: -44.5800 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.1672
Cell Significance Index: -3.5800 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.1702
Cell Significance Index: -2.3800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.2796
Cell Significance Index: -38.4000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3163
Cell Significance Index: -36.2400 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3198
Cell Significance Index: -36.5000 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.3541
Cell Significance Index: -45.7500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.3637
Cell Significance Index: -7.8800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.3701
Cell Significance Index: -37.8100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3927
Cell Significance Index: -20.6200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3943
Cell Significance Index: -41.0600 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.4018
Cell Significance Index: -5.3600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.4038
Cell Significance Index: -8.6000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.4270
Cell Significance Index: -50.3600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.4899
Cell Significance Index: -13.0800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.4991
Cell Significance Index: -35.3000 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.5103
Cell Significance Index: -10.0900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.5159
Cell Significance Index: -16.8900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.5680
Cell Significance Index: -18.0900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.5806
Cell Significance Index: -8.3200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5897
Cell Significance Index: -46.7100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.6404
Cell Significance Index: -47.7300 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.6898
Cell Significance Index: -9.9100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.7076
Cell Significance Index: -36.8600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7108
Cell Significance Index: -43.5800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.7208
Cell Significance Index: -19.6200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.7608
Cell Significance Index: -49.0800 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.8039
Cell Significance Index: -13.9000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.8604
Cell Significance Index: -40.4400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.8822
Cell Significance Index: -23.6400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.9131
Cell Significance Index: -57.5500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.9428
Cell Significance Index: -43.9600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -1.0061
Cell Significance Index: -34.9600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.0522
Cell Significance Index: -36.8600 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -1.0660
Cell Significance Index: -26.0100 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -1.0678
Cell Significance Index: -23.0700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -1.0976
Cell Significance Index: -18.3700 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -1.0996
Cell Significance Index: -11.9800 - Cell Name: preadipocyte (CL0002334)
Fold Change: -1.1257
Cell Significance Index: -21.9700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.1521
Cell Significance Index: -36.9000 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -1.1675
Cell Significance Index: -16.6200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1447129255
Symbol: PLXA2_HUMAN
Name: Plexin-A2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9455484
Title: Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.
PubMed ID: 9455484
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8570614
Title: A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.
PubMed ID: 8570614
PubMed ID: 10520995
Title: Plexins are a large family of receptors for transmembrane, secreted and GPI-anchored semaphorins in vertebrates.
PubMed ID: 10520995
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 1894
- Mass: 211104
- Checksum: DFC3DE5BCBB40357
- Sequence:
MEQRRPWPRA LEVDSRSVVL LSVVWVLLAP PAAGMPQFST FHSENRDWTF NHLTVHQGTG AVYVGAINRV YKLTGNLTIQ VAHKTGPEED NKSCYPPLIV QPCSEVLTLT NNVNKLLIID YSENRLLACG SLYQGVCKLL RLDDLFILVE PSHKKEHYLS SVNKTGTMYG VIVRSEGEDG KLFIGTAVDG KQDYFPTLSS RKLPRDPESS AMLDYELHSD FVSSLIKIPS DTLALVSHFD IFYIYGFASG GFVYFLTVQP ETPEGVAINS AGDLFYTSRI VRLCKDDPKF HSYVSLPFGC TRAGVEYRLL QAAYLAKPGD SLAQAFNITS QDDVLFAIFS KGQKQYHHPP DDSALCAFPI RAINLQIKER LQSCYQGEGN LELNWLLGKD VQCTKAPVPI DDNFCGLDIN QPLGGSTPVE GLTLYTTSRD RMTSVASYVY NGYSVVFVGT KSGKLKKIRA DGPPHGGVQY EMVSVLKDGS PILRDMAFSI DQRYLYVMSE RQVTRVPVES CEQYTTCGEC LSSGDPHCGW CALHNMCSRR DKCQQAWEPN RFAASISQCV SLAVHPSSIS VSEHSRLLSL VVSDAPDLSA GIACAFGNLT EVEGQVSGSQ VICISPGPKD VPVIPLDQDW FGLELQLRSK ETGKIFVSTE FKFYNCSAHQ LCLSCVNSAF RCHWCKYRNL CTHDPTTCSF QEGRINISED CPQLVPTEEI LIPVGEVKPI TLKARNLPQP QSGQRGYECV LNIQGAIHRV PALRFNSSSV QCQNSSYQYD GMDISNLAVD FAVVWNGNFI IDNPQDLKVH LYKCAAQRES CGLCLKADRK FECGWCSGER RCTLHQHCTS PSSPWLDWSS HNVKCSNPQI TEILTVSGPP EGGTRVTIHG VNLGLDFSEI AHHVQVAGVP CTPLPGEYII AEQIVCEMGH ALVGTTSGPV RLCIGECKPE FMTKSHQQYT FVNPSVLSLN PIRGPESGGT MVTITGHYLG AGSSVAVYLG NQTCEFYGRS MSEIVCVSPP SSNGLGPVPV SVSVDRAHVD SNLQFEYIDD PRVQRIEPEW SIASGHTPLT ITGFNLDVIQ EPRIRVKFNG KESVNVCKVV NTTTLTCLAP SLTTDYRPGL DTVERPDEFG FVFNNVQSLL IYNDTKFIYY PNPTFELLSP TGVLDQKPGS PIILKGKNLC PPASGGAKLN YTVLIGETPC AVTVSETQLL CEPPNLTGQH KVMVHVGGMV FSPGSVSVIS DSLLTLPAIV SIAAGGSLLL IIVIIVLIAY KRKSRENDLT LKRLQMQMDN LESRVALECK EAFAELQTDI NELTSDLDRS GIPYLDYRTY AMRVLFPGIE DHPVLRELEV QGNGQQHVEK ALKLFAQLIN NKVFLLTFIR TLELQRSFSM RDRGNVASLI MTGLQGRLEY ATDVLKQLLS DLIDKNLENK NHPKLLLRRT ESVAEKMLTN WFAFLLHKFL KECAGEPLFM LYCAIKQQME KGPIDAITGE ARYSLSEDKL IRQQIEYKTL ILNCVNPDNE NSPEIPVKVL NCDTITQVKE KILDAVYKNV PYSQRPRAVD MDLEWRQGRI ARVVLQDEDI TTKIEGDWKR LNTLMHYQVS DRSVVALVPK QTSSYNIPAS ASISRTSISR YDSSFRYTGS PDSLRSRAPM ITPDLESGVK VWHLVKNHDH GDQKEGDRGS KMVSEIYLTR LLATKGTLQK FVDDLFETLF STVHRGSALP LAIKYMFDFL DEQADRHSIH DTDVRHTWKS NCLPLRFWVN VIKNPQFVFD IHKGSITDAC LSVVAQTFMD SCSTSEHRLG KDSPSNKLLY AKDIPSYKSW VERYYADIAK LPAISDQDMN AYLAEQSRLH AVEFNMLSAL NEIYSYVSKY SEELIGALEQ DEQARRQRLA YKVEQLINAM SIES
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.