Details for: POU2F1

Gene ID: 5451

Symbol: POU2F1

Ensembl ID: ENSG00000143190

Description: POU class 2 homeobox 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 424.0567
    Cell Significance Index: -65.9600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 258.9068
    Cell Significance Index: -65.6700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 143.5114
    Cell Significance Index: -67.7600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 130.6562
    Cell Significance Index: -53.0800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 121.7376
    Cell Significance Index: -62.6200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 55.7323
    Cell Significance Index: -53.2100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 54.6978
    Cell Significance Index: -67.4400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 24.1045
    Cell Significance Index: -64.5700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 20.7622
    Cell Significance Index: -63.7700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 17.6369
    Cell Significance Index: -38.6000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 17.2793
    Cell Significance Index: -68.1900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 4.1021
    Cell Significance Index: 230.1900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 4.0450
    Cell Significance Index: 69.3200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 3.3516
    Cell Significance Index: 80.3800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 3.1173
    Cell Significance Index: 191.6100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.6465
    Cell Significance Index: 530.8800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.5298
    Cell Significance Index: 907.3900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.1074
    Cell Significance Index: 54.1700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.0672
    Cell Significance Index: 25.6400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.9572
    Cell Significance Index: 86.5700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.9275
    Cell Significance Index: 382.5200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.8927
    Cell Significance Index: 71.6700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.3412
    Cell Significance Index: 102.9300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.3209
    Cell Significance Index: 88.8200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.3132
    Cell Significance Index: 213.5800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.2558
    Cell Significance Index: 14.9700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.2202
    Cell Significance Index: 142.2000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.2182
    Cell Significance Index: 842.5400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.2077
    Cell Significance Index: 23.5700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.7860
    Cell Significance Index: 17.2100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.6926
    Cell Significance Index: 19.7700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6701
    Cell Significance Index: 72.8900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.6380
    Cell Significance Index: 40.2100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5217
    Cell Significance Index: 14.5800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.5078
    Cell Significance Index: 956.1500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.4985
    Cell Significance Index: 10.6600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4510
    Cell Significance Index: 85.8300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3667
    Cell Significance Index: 45.1000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.3262
    Cell Significance Index: 4.4500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.3227
    Cell Significance Index: 146.4700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.3120
    Cell Significance Index: 480.3500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.2959
    Cell Significance Index: 545.8000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2913
    Cell Significance Index: 52.5100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2836
    Cell Significance Index: 180.1400
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 0.2310
    Cell Significance Index: 3.2300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1951
    Cell Significance Index: 5.6200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1429
    Cell Significance Index: 78.0300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1417
    Cell Significance Index: 8.5100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1382
    Cell Significance Index: 187.8800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1344
    Cell Significance Index: 6.0900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1123
    Cell Significance Index: 7.7700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1013
    Cell Significance Index: 44.7800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0874
    Cell Significance Index: 8.6500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0102
    Cell Significance Index: 0.2200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0030
    Cell Significance Index: -0.0800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0225
    Cell Significance Index: -2.6500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0362
    Cell Significance Index: -4.9700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0469
    Cell Significance Index: -34.7200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0470
    Cell Significance Index: -1.6500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0518
    Cell Significance Index: -32.3300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0580
    Cell Significance Index: -42.5500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0738
    Cell Significance Index: -12.6100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0864
    Cell Significance Index: -48.7100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0880
    Cell Significance Index: -5.6800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0900
    Cell Significance Index: -68.1100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1619
    Cell Significance Index: -16.8600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1900
    Cell Significance Index: -27.6200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2027
    Cell Significance Index: -58.3100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2036
    Cell Significance Index: -42.8800
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2274
    Cell Significance Index: -3.2700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.3400
    Cell Significance Index: -43.5900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.3426
    Cell Significance Index: -35.0000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3517
    Cell Significance Index: -18.3200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3619
    Cell Significance Index: -18.8000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.4182
    Cell Significance Index: -54.0300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4717
    Cell Significance Index: -54.0400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5673
    Cell Significance Index: -29.7900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5743
    Cell Significance Index: -42.8000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5904
    Cell Significance Index: -67.3900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.6147
    Cell Significance Index: -28.6600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6188
    Cell Significance Index: -19.8200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7149
    Cell Significance Index: -56.6200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.7943
    Cell Significance Index: -19.3800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.8016
    Cell Significance Index: -56.6900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.8087
    Cell Significance Index: -15.9900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.8358
    Cell Significance Index: -17.8000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.8604
    Cell Significance Index: -40.4400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.8715
    Cell Significance Index: -30.2900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.8717
    Cell Significance Index: -17.5000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.8843
    Cell Significance Index: -28.1600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.8928
    Cell Significance Index: -29.2300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.9086
    Cell Significance Index: -15.7100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.9169
    Cell Significance Index: -19.4600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9258
    Cell Significance Index: -56.7600
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.9384
    Cell Significance Index: -13.8500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.9679
    Cell Significance Index: -14.2900
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.9683
    Cell Significance Index: -12.0800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -1.0642
    Cell Significance Index: -9.8000
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.1607
    Cell Significance Index: -14.6500
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -1.1629
    Cell Significance Index: -16.7300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** POU2F1 is a transcription factor gene that belongs to the POU domain-containing family, which is characterized by the presence of a POU homeodomain. The POU homeodomain is a conserved DNA-binding domain that is responsible for recognizing and binding to specific DNA sequences. POU2F1 is a type II POU transcription factor, which means that it contains a POU homeodomain and a POUF1 domain. The POUF1 domain is involved in protein-protein interactions and is necessary for the transcriptional activation of target genes. POU2F1 is a multifunctional transcription factor that regulates gene expression in various cell types, including photoreceptor cells, stellate neurons, and immune cells. It is involved in regulating the expression of genes involved in cell differentiation, survival, and immune responses. **Pathways and Functions** POU2F1 is involved in several signaling pathways, including: 1. **Chromatin remodeling**: POU2F1 regulates chromatin remodeling by interacting with chromatin-modifying enzymes, such as histone acetyltransferases and histone deacetylases. 2. **Cytokine signaling**: POU2F1 regulates cytokine signaling by interacting with cytokine receptors and transcription factors, such as STAT1 and STAT3. 3. **DNA-binding transcription activator activity**: POU2F1 regulates DNA-binding transcription activator activity by interacting with RNA polymerase II and other transcription factors. 4. **RNA polymerase II-specific transcription**: POU2F1 regulates RNA polymerase II-specific transcription by interacting with RNA polymerase II and other transcription factors. POU2F1 functions as a transcriptional activator or repressor, depending on the context. In photoreceptor cells, POU2F1 regulates the expression of genes involved in phototransduction and visual signaling. In immune cells, POU2F1 regulates the expression of genes involved in immune responses, such as cytokine production and antigen presentation. **Clinical Significance** POU2F1 has been implicated in several neurological and immune disorders, including: 1. **Retinal degeneration**: POU2F1 has been shown to regulate the expression of genes involved in phototransduction and visual signaling, and mutations in the POU2F1 gene have been associated with retinal degeneration. 2. **Neurological disorders**: POU2F1 has been implicated in several neurological disorders, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. 3. **Autoimmune diseases**: POU2F1 has been shown to regulate cytokine production and immune responses, and dysregulation of POU2F1 has been implicated in autoimmune diseases, such as rheumatoid arthritis and lupus. Overall, POU2F1 is a multifunctional transcription factor that plays a crucial role in regulating gene expression in various cell types, particularly in the nervous system and immune system. Its dysregulation has been implicated in several neurological and immune disorders, highlighting its potential as a therapeutic target for the treatment of these diseases.

Genular Protein ID: 1184942578

Symbol: PO2F1_HUMAN

Name: POU domain, class 2, transcription factor 1

UniProtKB Accession Codes:

P14859 B1AL91 B1AL93 B4E029 J3KP77 Q5TBT7 Q6PK46 Q8NEU9 Q9BPV1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 1 EMBL 12 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MoonProt 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PRINTS 2 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 5 RefSeq 4 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2905684

Title: The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

PubMed ID: 2905684

DOI: 10.1101/gad.2.12a.1582

PubMed ID: 12663137

Title: Human Oct-1L isoform has tissue-specific expression pattern similar to Oct-2.

PubMed ID: 12663137

DOI: 10.1016/s0165-2478(02)00179-7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1684878

Title: Mitotic phosphorylation of the Oct-1 homeodomain and regulation of Oct-1 DNA binding activity.

PubMed ID: 1684878

DOI: 10.1126/science.1684878

PubMed ID: 7859290

Title: OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins.

PubMed ID: 7859290

DOI: 10.1016/0092-8674(95)90500-6

PubMed ID: 10480874

Title: Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the mouse mammary tumor virus promoter.

PubMed ID: 10480874

DOI: 10.1074/jbc.274.38.26713

PubMed ID: 10629049

Title: Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIP.

PubMed ID: 10629049

DOI: 10.1128/mcb.20.3.919-928.2000

PubMed ID: 14612514

Title: Down-regulation of histone H2B by DNA-dependent protein kinase in response to DNA damage through modulation of octamer transcription factor 1.

PubMed ID: 14612514

PubMed ID: 12826401

Title: The herpes simplex virus VP16-induced complex: the makings of a regulatory switch.

PubMed ID: 12826401

DOI: 10.1016/s0968-0004(03)00088-4

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17537858

Title: Direct interactions of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50/Rta protein with the cellular protein octamer-1 and DNA are critical for specifying transactivation of a delayed-early promoter and stimulating viral reactivation.

PubMed ID: 17537858

DOI: 10.1128/jvi.00265-07

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 8479524

Title: Solution structure of the POU-specific DNA-binding domain of Oct-1.

PubMed ID: 8479524

DOI: 10.1038/362852a0

PubMed ID: 8462099

Title: The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage lambda repressor DNA-binding domain.

PubMed ID: 8462099

DOI: 10.1016/0092-8674(93)90171-l

PubMed ID: 7663141

Title: Solution structure of the Oct-1 POU homeodomain determined by NMR and restrained molecular dynamics.

PubMed ID: 7663141

DOI: 10.1007/bf00417488

PubMed ID: 8156594

Title: Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules.

PubMed ID: 8156594

DOI: 10.1016/0092-8674(94)90231-3

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 743
  • Mass: 76472
  • Checksum: FAB27FFC79CF2276
  • Sequence:
    • MNNPSETSKP SMESGDGNTG TQTNGLDFQK QPVPVGGAIS TAQAQAFLGH LHQVQLAGTS 
LQAAAQSLNV QSKSNEESGD SQQPSQPSQQ PSVQAAIPQT QLMLAGGQIT GLTLTPAQQQ 
LLLQQAQAQA QLLAAAVQQH SASQQHSAAG ATISASAATP MTQIPLSQPI QIAQDLQQLQ 
QLQQQNLNLQ QFVLVHPTTN LQPAQFIISQ TPQGQQGLLQ AQNLLTQLPQ QSQANLLQSQ 
PSITLTSQPA TPTRTIAATP IQTLPQSQST PKRIDTPSLE EPSDLEELEQ FAKTFKQRRI 
KLGFTQGDVG LAMGKLYGND FSQTTISRFE ALNLSFKNMC KLKPLLEKWL NDAENLSSDS 
SLSSPSALNS PGIEGLSRRR KKRTSIETNI RVALEKSFLE NQKPTSEEIT MIADQLNMEK 
EVIRVWFCNR RQKEKRINPP SSGGTSSSPI KAIFPSPTSL VATTPSLVTS SAATTLTVSP 
VLPLTSAAVT NLSVTGTSDT TSNNTATVIS TAPPASSAVT SPSLSPSPSA SASTSEASSA 
SETSTTQTTS TPLSSPLGTS QVMVTASGLQ TAAAAALQGA AQLPANASLA AMAAAAGLNP 
SLMAPSQFAA GGALLSLNPG TLSGALSPAL MSNSTLATIQ ALASGGSLPI TSLDATGNLV 
FANAGGAPNI VTAPLFLNPQ NLSLLTSNPV SLVSAAAASA GNSAPVASLH ATSTSAESIQ 
NSLFTVASAS GAASTTTTAS KAQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.