Details for: POU2F2

Gene ID: 5452

Symbol: POU2F2

Ensembl ID: ENSG00000028277

Description: POU class 2 homeobox 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 140.0879
    Cell Significance Index: -21.7900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 72.5428
    Cell Significance Index: -18.4000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 57.9436
    Cell Significance Index: -23.5400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 52.6454
    Cell Significance Index: -27.0800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 17.6730
    Cell Significance Index: -21.7900
  • Cell Name: centroblast (CL0009112)
    Fold Change: 9.9612
    Cell Significance Index: 23.2400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.7239
    Cell Significance Index: -23.3700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.9874
    Cell Significance Index: -18.3900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.5828
    Cell Significance Index: -22.0300
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 4.7972
    Cell Significance Index: 74.2200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 3.5379
    Cell Significance Index: 417.2300
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 1.9164
    Cell Significance Index: 8.5700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.4401
    Cell Significance Index: 92.9100
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 1.2027
    Cell Significance Index: 9.2700
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 1.0781
    Cell Significance Index: 11.2300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0752
    Cell Significance Index: 215.6800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.0211
    Cell Significance Index: 29.9900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.0102
    Cell Significance Index: 12.5300
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.6612
    Cell Significance Index: 12.2200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6313
    Cell Significance Index: 120.1500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.5159
    Cell Significance Index: 13.8000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4484
    Cell Significance Index: 160.8300
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 0.4265
    Cell Significance Index: 1.3200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.4095
    Cell Significance Index: 25.1700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.3678
    Cell Significance Index: 16.2700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3221
    Cell Significance Index: 290.8700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.3095
    Cell Significance Index: 20.8100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2836
    Cell Significance Index: 10.7400
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 0.2724
    Cell Significance Index: 1.6500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2338
    Cell Significance Index: 161.7000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1343
    Cell Significance Index: 21.8500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1144
    Cell Significance Index: 1.9600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1096
    Cell Significance Index: 10.8400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0992
    Cell Significance Index: 5.2100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0487
    Cell Significance Index: 5.6800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0366
    Cell Significance Index: 3.9900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0313
    Cell Significance Index: 0.7500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0064
    Cell Significance Index: 12.1000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0024
    Cell Significance Index: 0.4300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0097
    Cell Significance Index: -17.9600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0097
    Cell Significance Index: -14.8700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0118
    Cell Significance Index: -2.3400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0168
    Cell Significance Index: -22.8600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0172
    Cell Significance Index: -9.4100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0176
    Cell Significance Index: -0.6200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0179
    Cell Significance Index: -7.9300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0231
    Cell Significance Index: -2.8400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0278
    Cell Significance Index: -0.8000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0305
    Cell Significance Index: -23.0800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0316
    Cell Significance Index: -20.0700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0323
    Cell Significance Index: -23.9400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0344
    Cell Significance Index: -25.2300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0390
    Cell Significance Index: -21.9900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0409
    Cell Significance Index: -25.5400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0439
    Cell Significance Index: -19.9100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0587
    Cell Significance Index: -4.0600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0647
    Cell Significance Index: -18.6100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0708
    Cell Significance Index: -3.2100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0905
    Cell Significance Index: -5.0800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1031
    Cell Significance Index: -10.5400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1034
    Cell Significance Index: -2.2400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1110
    Cell Significance Index: -18.9500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1158
    Cell Significance Index: -16.8400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1190
    Cell Significance Index: -25.0700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1303
    Cell Significance Index: -17.8900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.1424
    Cell Significance Index: -8.5500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1493
    Cell Significance Index: -19.1400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1577
    Cell Significance Index: -20.3800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1820
    Cell Significance Index: -4.5500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1822
    Cell Significance Index: -3.9900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2035
    Cell Significance Index: -10.5700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2039
    Cell Significance Index: -21.2300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2121
    Cell Significance Index: -15.0000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2123
    Cell Significance Index: -6.8000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2175
    Cell Significance Index: -24.9200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2213
    Cell Significance Index: -10.4000
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.2309
    Cell Significance Index: -3.0800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2339
    Cell Significance Index: -7.4500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2364
    Cell Significance Index: -3.3900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2452
    Cell Significance Index: -15.0300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2580
    Cell Significance Index: -19.8000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2847
    Cell Significance Index: -9.3200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2991
    Cell Significance Index: -8.3600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3052
    Cell Significance Index: -22.7500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3301
    Cell Significance Index: -9.4200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3577
    Cell Significance Index: -7.4200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3656
    Cell Significance Index: -23.0400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3719
    Cell Significance Index: -17.3400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3790
    Cell Significance Index: -7.5000
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: -0.3964
    Cell Significance Index: -2.6300
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.3981
    Cell Significance Index: -17.3100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.4169
    Cell Significance Index: -8.3700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4278
    Cell Significance Index: -14.9900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4381
    Cell Significance Index: -22.8200
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.4461
    Cell Significance Index: -7.6900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.4517
    Cell Significance Index: -12.0600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.5143
    Cell Significance Index: -12.8300
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.5199
    Cell Significance Index: -6.4800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.5245
    Cell Significance Index: -13.4000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.5264
    Cell Significance Index: -11.1700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** POU2F2 is a transcription factor that belongs to the POU family of proteins, which are characterized by their presence of a POU domain. This domain is responsible for the recognition and binding of specific DNA sequences. POU2F2 is specifically expressed in lymphoid cells and is involved in the regulation of gene expression in these cells. Its expression is also observed in non-lymphoid cells, including chromaffin cells, suggesting a broader role in the regulation of gene expression. **Pathways and Functions:** POU2F2 is involved in several key pathways, including: 1. **Cellular response to virus**: POU2F2 is involved in the regulation of transcription in response to viral infections, highlighting its role in the immune response. 2. **Gene expression (transcription)**: POU2F2 regulates transcription by RNA polymerase II, which is essential for the expression of genes involved in immune response. 3. **Humoral immune response**: POU2F2 is involved in the regulation of interleukin-6 production, which is a key cytokine in the humoral immune response. 4. **Chromatin regulation**: POU2F2 is involved in the regulation of chromatin structure, which is essential for the expression of genes involved in immune response. **Functions:** POU2F2 functions as a transcription factor that regulates gene expression in lymphoid cells. Its primary function is to bind to specific DNA sequences and recruit RNA polymerase II to initiate transcription. POU2F2 also regulates the expression of genes involved in the humoral immune response, including interleukin-6. Additionally, POU2F2 is involved in the regulation of chromatin structure, which is essential for the expression of genes involved in immune response. **Clinical Significance:** POU2F2 has been implicated in various immune-related disorders, including autoimmune diseases and cancer. Dysregulation of POU2F2 has been observed in these disorders, highlighting its importance as a potential therapeutic target. For example, POU2F2 has been shown to be overexpressed in certain types of cancer, suggesting that it may play a role in tumorigenesis. Additionally, POU2F2 has been implicated in autoimmune diseases, such as rheumatoid arthritis, where it is thought to contribute to the dysregulation of the immune response. In conclusion, POU2F2 is a critical regulator of immune response and gene expression. Its dysregulation has been implicated in various immune-related disorders, highlighting its importance as a potential therapeutic target. Further research is needed to fully understand the role of POU2F2 in the regulation of immune response and its implications for human disease.

Genular Protein ID: 2412708140

Symbol: PO2F2_HUMAN

Name: Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2

UniProtKB Accession Codes:

P09086 Q16648 Q7M4M8 Q9BRS4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 EMBL 10 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 2 PRINTS 2 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3265124

Title: The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains.

PubMed ID: 3265124

DOI: 10.1101/gad.2.12a.1570

PubMed ID: 2904654

Title: A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein.

PubMed ID: 2904654

DOI: 10.1038/336551a0

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2904653

Title: A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells.

PubMed ID: 2904653

DOI: 10.1038/336544a0

PubMed ID: 2328728

Title: Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells.

PubMed ID: 2328728

DOI: 10.1002/j.1460-2075.1990.tb08282.x

PubMed ID: 7888080

Title: Short introns interrupting the Oct-2 POU domain may prevent recombination between POU family genes without interfering with potential POU domain 'shuffling' in evolution.

PubMed ID: 7888080

DOI: 10.1515/bchm3.1994.375.10.675

PubMed ID: 2901913

Title: A human protein specific for the immunoglobulin octamer DNA motif contains a functional homeobox domain.

PubMed ID: 2901913

DOI: 10.1016/0092-8674(88)90016-5

PubMed ID: 1739980

Title: Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter.

PubMed ID: 1739980

DOI: 10.1016/0092-8674(92)90150-b

PubMed ID: 3072196

Title: Identification of a novel lymphoid specific octamer binding protein (OTF-2B) by proteolytic clipping bandshift assay (PCBA).

PubMed ID: 3072196

DOI: 10.1002/j.1460-2075.1988.tb03319.x

PubMed ID: 7859290

Title: OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins.

PubMed ID: 7859290

DOI: 10.1016/0092-8674(95)90500-6

PubMed ID: 10480874

Title: Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the mouse mammary tumor virus promoter.

PubMed ID: 10480874

DOI: 10.1074/jbc.274.38.26713

PubMed ID: 7914745

Title: Solution structure of a POU-specific homeodomain: 3D-NMR studies of human B-cell transcription factor Oct-2.

PubMed ID: 7914745

DOI: 10.1021/bi00199a005

Sequence Information:

  • Length: 479
  • Mass: 51209
  • Checksum: 8DA661DC07644D43
  • Sequence:
    • MVHSSMGAPE IRMSKPLEAE KQGLDSPSEH TDTERNGPDT NHQNPQNKTS PFSVSPTGPS 
TKIKAEDPSG DSAPAAPLPP QPAQPHLPQA QLMLTGSQLA GDIQQLLQLQ QLVLVPGHHL 
QPPAQFLLPQ AQQSQPGLLP TPNLFQLPQQ TQGALLTSQP RAGLPTQAVT RPTLPDPHLS 
HPQPPKCLEP PSHPEEPSDL EELEQFARTF KQRRIKLGFT QGDVGLAMGK LYGNDFSQTT 
ISRFEALNLS FKNMCKLKPL LEKWLNDAET MSVDSSLPSP NQLSSPSLGF DGLPGRRRKK 
RTSIETNVRF ALEKSFLANQ KPTSEEILLI AEQLHMEKEV IRVWFCNRRQ KEKRINPCSA 
APMLPSPGKP ASYSPHMVTP QGGAGTLPLS QASSSLSTTV TTLSSAVGTL HPSRTAGGGG 
GGGGAAPPLN SIPSVTPPPP ATTNSTNPSP QGSHSAIGLS GLNPSTGPGL WWNPAPYQP

Genular Protein ID: 3840866519

Symbol: H0YLL6_HUMAN

Name: N/A

UniProtKB Accession Codes:

H0YLL6

Database IDs:

ARBA 7 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 2 GeneTree 1 HGNC 1 InterPro 8 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 2 SAM 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 485
  • Mass: 51720
  • Checksum: C2003C596EEBA5D5
  • Sequence:
    • MVHSSMGAPE IRMSKPLEAE KQGLDSPSEH TDTERNGPDT NHQNPQNKTS PFSVSPTGPS 
TKVGILSGLH LTFWGPGPCL SPPQIKAEDP SGDSAPAAPL PPQPAQPHLP QAQLMLTGSQ 
LAGDIQQLLQ LQQLVLVPGH HLQPPAQFLL PQAQQSQPGL LPTPNLFQLP QQTQGALLTS 
QPRAGLPTQP PKCLEPPSHP EEPSDLEELE QFARTFKQRR IKLGFTQGDV GLAMGKLYGN 
DFSQTTISRF EALNLSFKNM CKLKPLLEKW LNDAETMSVD SSLPSPNQLS SPSLGFDGLP 
GRRRKKRTSI ETNVRFALEK SFLANQKPTS EEILLIAEQL HMEKEVIRVW FCNRRQKEKR 
INPCSAAPML PSPGKPASYS PHMVTPQGGA GTLPLSQASS SLSTTVTTLS SAVGTLHPSR 
TAGGGGGGGG AAPPLNSIPS VTPPPPATTN STNPSPQGSH SAIGLSGLNP STGPGLWWNP 
APYQP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.