Details for: PRKG2

Gene ID: 5593

Symbol: PRKG2

Ensembl ID: ENSG00000138669

Description: protein kinase cGMP-dependent 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 88.2701
    Cell Significance Index: -13.7300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 48.7693
    Cell Significance Index: -12.3700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 11.1845
    Cell Significance Index: -13.7900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.5917
    Cell Significance Index: 302.9200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.3524
    Cell Significance Index: 20.2700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.1057
    Cell Significance Index: 35.4200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8330
    Cell Significance Index: 298.7800
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.7819
    Cell Significance Index: 18.9400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6780
    Cell Significance Index: 67.0700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.6322
    Cell Significance Index: 6.5500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5835
    Cell Significance Index: 35.0300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5801
    Cell Significance Index: 16.7200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5797
    Cell Significance Index: 12.5600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4818
    Cell Significance Index: 52.4100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4144
    Cell Significance Index: 83.1200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.3975
    Cell Significance Index: 3.6600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3836
    Cell Significance Index: 62.3900
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.3470
    Cell Significance Index: 4.5000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3173
    Cell Significance Index: 21.9400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.3108
    Cell Significance Index: 7.7700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2259
    Cell Significance Index: 10.2400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1663
    Cell Significance Index: 115.0500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1657
    Cell Significance Index: 8.6100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1091
    Cell Significance Index: 98.5400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0683
    Cell Significance Index: 4.2000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0652
    Cell Significance Index: 11.7500
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.0634
    Cell Significance Index: 0.7900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0603
    Cell Significance Index: 7.4100
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.0448
    Cell Significance Index: 0.7100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0343
    Cell Significance Index: 0.9800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.0169
    Cell Significance Index: 0.3300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0017
    Cell Significance Index: 0.0600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0030
    Cell Significance Index: -0.0600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0035
    Cell Significance Index: -0.4100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0042
    Cell Significance Index: -7.9300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0074
    Cell Significance Index: -13.5900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0094
    Cell Significance Index: -14.5300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0111
    Cell Significance Index: -15.0300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0131
    Cell Significance Index: -5.9300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0140
    Cell Significance Index: -10.2500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0141
    Cell Significance Index: -6.2400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0158
    Cell Significance Index: -11.9300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0162
    Cell Significance Index: -10.2900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0163
    Cell Significance Index: -12.0900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0223
    Cell Significance Index: -12.1800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0229
    Cell Significance Index: -14.2700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0246
    Cell Significance Index: -13.8900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0294
    Cell Significance Index: -0.6100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0354
    Cell Significance Index: -0.8500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0374
    Cell Significance Index: -10.7700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0426
    Cell Significance Index: -8.4600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0440
    Cell Significance Index: -0.9500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0440
    Cell Significance Index: -0.6300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0599
    Cell Significance Index: -8.7100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0606
    Cell Significance Index: -1.2900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0758
    Cell Significance Index: -4.6500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0762
    Cell Significance Index: -16.0400
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0776
    Cell Significance Index: -0.9800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0805
    Cell Significance Index: -13.7400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0957
    Cell Significance Index: -10.9600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0961
    Cell Significance Index: -13.2000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1028
    Cell Significance Index: -13.2800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1048
    Cell Significance Index: -1.5800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1049
    Cell Significance Index: -12.3700
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.1056
    Cell Significance Index: -1.5000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1142
    Cell Significance Index: -7.6800
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1283
    Cell Significance Index: -5.5800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1303
    Cell Significance Index: -2.7700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1305
    Cell Significance Index: -13.3300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1327
    Cell Significance Index: -13.8200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1392
    Cell Significance Index: -6.4900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1505
    Cell Significance Index: -11.9200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1706
    Cell Significance Index: -13.0900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1797
    Cell Significance Index: -13.4000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1848
    Cell Significance Index: -4.6100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1970
    Cell Significance Index: -10.2600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2047
    Cell Significance Index: -12.9000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2074
    Cell Significance Index: -13.3800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2114
    Cell Significance Index: -10.6900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2115
    Cell Significance Index: -11.8700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2147
    Cell Significance Index: -7.0300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2208
    Cell Significance Index: -6.1700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2538
    Cell Significance Index: -11.9300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2549
    Cell Significance Index: -8.9300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2600
    Cell Significance Index: -11.5000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2609
    Cell Significance Index: -13.7000
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.2711
    Cell Significance Index: -2.5700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3211
    Cell Significance Index: -12.1600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3273
    Cell Significance Index: -6.8500
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.3329
    Cell Significance Index: -3.4500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3462
    Cell Significance Index: -8.9000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3473
    Cell Significance Index: -12.0700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3572
    Cell Significance Index: -11.3800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.3678
    Cell Significance Index: -5.9000
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.3855
    Cell Significance Index: -4.2000
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.3938
    Cell Significance Index: -7.7500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4037
    Cell Significance Index: -11.8900
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.4153
    Cell Significance Index: -5.4200
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.4188
    Cell Significance Index: -8.7400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4432
    Cell Significance Index: -16.2700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **cGMP-dependent protein kinase activity:** PRKG2 is a member of the cGMP-dependent protein kinase family, which is activated by the binding of cyclic guanosine monophosphate (cGMP) to the enzyme. This activation leads to the phosphorylation of downstream targets, thereby modulating cellular responses. 2. **Wnt signaling pathway regulation:** PRKG2 is involved in the negative regulation of Wnt signaling pathways, which are critical for cell proliferation, differentiation, and survival. The dysregulation of Wnt signaling has been implicated in various disease states, including cancer and neurological disorders. 3. **Nitric oxide stimulation:** PRKG2 is activated by nitric oxide, a potent vasodilator that plays a crucial role in cardiovascular function. The activation of PRKG2 by nitric oxide leads to the regulation of various cellular processes, including vascular smooth muscle relaxation and platelet aggregation. 4. **Cell type-specific expression:** PRKG2 is expressed in multiple cell types, including retinal bipolar neurons, GABAergic cortical interneurons, and brainstem motor neurons. The expression of PRKG2 is tightly regulated and is essential for maintaining proper cellular function. **Pathways and Functions:** 1. **Ca2+ pathway:** PRKG2 is involved in the regulation of calcium-dependent signaling pathways, which are critical for various cellular processes, including muscle contraction, neurotransmitter release, and cell proliferation. 2. **Apical plasma membrane:** PRKG2 is localized to the apical plasma membrane, where it regulates the activity of various ion channels and transporters, including chloride channels and potassium channels. 3. **Metabolism:** PRKG2 is involved in the regulation of metabolic pathways, including the metabolism of cofactors, vitamins, and tetrahydrobiopterin (BH4). 4. **Hemostasis:** PRKG2 plays a critical role in regulating platelet aggregation and hemostasis, which are essential for maintaining proper vascular function. **Clinical Significance:** 1. **Cardiovascular disorders:** The dysregulation of PRKG2 has been implicated in various cardiovascular disorders, including hypertension, atherosclerosis, and heart failure. 2. **Neurological conditions:** PRKG2 has been implicated in the regulation of neurological conditions, including Parkinson's disease, Alzheimer's disease, and multiple sclerosis. 3. **Hematological malignancies:** PRKG2 has been implicated in the regulation of hematopoiesis and has been associated with various hematological malignancies, including acute myeloid leukemia and chronic myeloid leukemia. 4. **Cancer:** PRKG2 has been implicated in the regulation of cancer cell growth, invasion, and metastasis, and has been associated with various types of cancer, including breast cancer, lung cancer, and colon cancer. In conclusion, PRKG2 is a crucial enzyme that plays a pivotal role in regulating various cellular signaling pathways, including Wnt signaling, Ca2+ pathways, and metabolism. The dysregulation of PRKG2 has been implicated in various disease states, including cardiovascular disorders, neurological conditions, and hematological malignancies. Further research is necessary to fully understand the mechanisms by which PRKG2 regulates cellular function and to identify potential therapeutic targets for the treatment of these diseases.

Genular Protein ID: 2768399758

Symbol: KGP2_HUMAN

Name: cGMP-dependent protein kinase 2

UniProtKB Accession Codes:

Q13237 B4DMX3 E7EPE6 O00125 O60916

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CTD 1 ChEBI 21 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EC 3 EMBL 23 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 7 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 4 RefSeq 9 Rhea 6 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8607838

Title: Molecular cloning, cDNA structure, and chromosomal localization of the human type II cGMP-dependent protein kinase.

PubMed ID: 8607838

DOI: 10.1006/bbrc.1996.0477

PubMed ID: 7498513

Title: Expression of the human cGMP-dependent protein kinase II gene is lost upon introduction of SV40 T antigen or immortalization in human cells.

PubMed ID: 7498513

DOI: 10.1016/0014-5793(95)01223-2

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 9535793

Title: Characterization of the gene encoding the human type II cGMP-dependent protein kinase.

PubMed ID: 9535793

DOI: 10.1006/bbrc.1998.8399

PubMed ID: 8636133

Title: N-terminal myristoylation is required for membrane localization of cGMP-dependent protein kinase type II.

PubMed ID: 8636133

DOI: 10.1074/jbc.271.12.7025

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

PubMed ID: 34782440

Title: Variable skeletal phenotypes associated with biallelic variants in PRKG2.

PubMed ID: 34782440

DOI: 10.1136/jmedgenet-2021-108027

PubMed ID: 33106379

Title: Biallelic cGMP-dependent type II protein kinase gene (PRKG2) variants cause a novel acromesomelic dysplasia.

PubMed ID: 33106379

DOI: 10.1136/jmedgenet-2020-107177

PubMed ID: 26769964

Title: Structural basis of cyclic nucleotide selectivity in cGMP-dependent protein kinase II.

PubMed ID: 26769964

DOI: 10.1074/jbc.m115.691303

Sequence Information:

  • Length: 762
  • Mass: 87432
  • Checksum: FA7BA149906B5996
  • Sequence:
    • MGNGSVKPKH SKHPDGHSGN LTTDALRNKV TELERELRRK DAEIQEREYH LKELREQLSK 
QTVAIAELTE ELQNKCIQLN KLQDVVHMQG GSPLQASPDK VPLEVHRKTS GLVSLHSRRG 
AKAGVSAEPT TRTYDLNKPP EFSFEKARVR KDSSEKKLIT DALNKNQFLK RLDPQQIKDM 
VECMYGRNYQ QGSYIIKQGE PGNHIFVLAE GRLEVFQGEK LLSSIPMWTT FGELAILYNC 
TRTASVKAIT NVKTWALDRE VFQNIMRRTA QARDEQYRNF LRSVSLLKNL PEDKLTKIID 
CLEVEYYDKG DYIIREGEEG STFFILAKGK VKVTQSTEGH DQPQLIKTLQ KGEYFGEKAL 
ISDDVRSANI IAEENDVACL VIDRETFNQT VGTFEELQKY LEGYVANLNR DDEKRHAKRS 
MSNWKLSKAL SLEMIQLKEK VARFSSSSPF QNLEIIATLG VGGFGRVELV KVKNENVAFA 
MKCIRKKHIV DTKQQEHVYS EKRILEELCS PFIVKLYRTF KDNKYVYMLL EACLGGELWS 
ILRDRGSFDE PTSKFCVACV TEAFDYLHRL GIIYRDLKPE NLILDAEGYL KLVDFGFAKK 
IGSGQKTWTF CGTPEYVAPE VILNKGHDFS VDFWSLGILV YELLTGNPPF SGVDQMMTYN 
LILKGIEKMD FPRKITRRPE DLIRRLCRQN PTERLGNLKN GINDIKKHRW LNGFNWEGLK 
ARSLPSPLQR ELKGPIDHSY FDKYPPEKGM PPDELSGWDK DF

Genular Protein ID: 2030624883

Symbol: B4DLF9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DLF9

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 1

Sequence Information:

  • Length: 342
  • Mass: 39420
  • Checksum: 3C74319D8BAF21AF
  • Sequence:
    • MSNWKLSKAL SLEMIQLKEK VARFSSSSPF QNLEIIATLG VGGFGRVELV KVKNENVAFA 
MKCIRKKHIV DTKQQEHVYS EKRILEELCS PFIVKLYRTF KDNKYVYMLL EACLGGELWS 
ILRDRGSFDE PTSKFCVACV TEAFDYLHRL GIIYRDLKPE NLILDAEGYL KLVDFGFAKK 
IGSGQKTWTF CGTPEYVAPE VILNKGHDFS VDFWSLGILV YELLTGNPPF SGVDQMMTYS 
LILKGIEKMD FPRKITRRPE DLIRRLCRQN PTERLGNLKN GINDIKKHRW LNGFNWEGLK 
ARSLPSPLQR ELKGPIDHSY FDKYPPEKGM PPDELSGWDK DF

Genular Protein ID: 2581598349

Symbol: B7ZA25_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7ZA25

Database IDs:

ARBA 5 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 2 GO 2 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 6 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 4 RuleBase 1 SAM 1 SMART 2 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 342
  • Mass: 39447
  • Checksum: BEFE193F1A163151
  • Sequence:
    • MSNWKLSKAL SLEMIQLKEK VARFSSSSPF QNLEIIATLG VGGFGRVELV KVKNENVAFA 
MKCIRKKHIV DTKQQEHVYS EKRILEELCS PFIVKLYRTF KDNKYVYMLL EACLGGELWS 
ILRDRGSFDE PTSKFCVACV TEAFDYLHRL GIIYRDLKPE NLILDAEGYL KLVDFGFAKK 
IGSGQKTWTF CGTPEYVAPE VILNKGHDFS VDFWSLGILV YELLTGNPPF SGVDQMMTYN 
LILKGIEKMD FPRKITRRPE DLIRRLCRQN PTERLGNLKN GINDIKKHRW LNGFNWEGLK 
ARSLPSPLQR ELKGPIDHSY FDKYPPEKGM PPDELSGWDK DF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.