Details for: RAP1GAP

Gene ID: 5909

Symbol: RAP1GAP

Ensembl ID: ENSG00000076864

Description: RAP1 GTPase activating protein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 162.5894
    Cell Significance Index: -25.2900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 67.5571
    Cell Significance Index: -27.8300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 55.3098
    Cell Significance Index: -22.4700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 39.1939
    Cell Significance Index: -26.3000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 20.2440
    Cell Significance Index: -24.9600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.5976
    Cell Significance Index: 159.1300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.1940
    Cell Significance Index: 120.9500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.9287
    Cell Significance Index: 36.3300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.2072
    Cell Significance Index: 442.7600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.1416
    Cell Significance Index: 148.1100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.1228
    Cell Significance Index: 56.8800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 1.6091
    Cell Significance Index: 45.9200
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 1.4726
    Cell Significance Index: 15.9600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 1.2866
    Cell Significance Index: 45.2100
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 1.2245
    Cell Significance Index: 13.0100
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.1330
    Cell Significance Index: 8.6900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.0618
    Cell Significance Index: 55.7500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.8239
    Cell Significance Index: 49.4600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8174
    Cell Significance Index: 293.2000
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.8084
    Cell Significance Index: 11.5900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.7461
    Cell Significance Index: 38.7600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.6542
    Cell Significance Index: 452.4700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.6469
    Cell Significance Index: 30.1600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5910
    Cell Significance Index: 533.6000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.5505
    Cell Significance Index: 64.1500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.4663
    Cell Significance Index: 79.6300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4554
    Cell Significance Index: 30.6200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4094
    Cell Significance Index: 11.8000
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.3276
    Cell Significance Index: 4.3700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3230
    Cell Significance Index: 64.1000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2671
    Cell Significance Index: 26.4300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1900
    Cell Significance Index: 4.7500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1725
    Cell Significance Index: 7.8200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1305
    Cell Significance Index: 23.5200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1185
    Cell Significance Index: 22.5600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.0814
    Cell Significance Index: 0.7500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0664
    Cell Significance Index: 36.2500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0601
    Cell Significance Index: 44.0500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0531
    Cell Significance Index: 6.0800
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 0.0166
    Cell Significance Index: 0.7200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0127
    Cell Significance Index: 23.8700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.0007
    Cell Significance Index: 0.5000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0082
    Cell Significance Index: -6.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0108
    Cell Significance Index: -20.0100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0140
    Cell Significance Index: -21.5200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0164
    Cell Significance Index: -9.2600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0178
    Cell Significance Index: -11.2900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0183
    Cell Significance Index: -11.4200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0186
    Cell Significance Index: -25.2600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0257
    Cell Significance Index: -1.5800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0296
    Cell Significance Index: -0.6300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0318
    Cell Significance Index: -14.0700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0383
    Cell Significance Index: -0.8300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0464
    Cell Significance Index: -5.7000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0557
    Cell Significance Index: -25.2700
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: -0.0581
    Cell Significance Index: -0.2200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0612
    Cell Significance Index: -12.8900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0713
    Cell Significance Index: -20.5100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0713
    Cell Significance Index: -11.5900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0902
    Cell Significance Index: -13.1100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1074
    Cell Significance Index: -13.7700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1185
    Cell Significance Index: -2.5200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1238
    Cell Significance Index: -12.6500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1316
    Cell Significance Index: -8.0700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1327
    Cell Significance Index: -1.9000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1379
    Cell Significance Index: -17.8100
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1387
    Cell Significance Index: -1.7300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1627
    Cell Significance Index: -12.8900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1656
    Cell Significance Index: -22.7400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1673
    Cell Significance Index: -3.4700
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.1902
    Cell Significance Index: -1.8100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1992
    Cell Significance Index: -15.2900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2138
    Cell Significance Index: -7.0000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2145
    Cell Significance Index: -24.4900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2207
    Cell Significance Index: -16.4500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2261
    Cell Significance Index: -6.3200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2277
    Cell Significance Index: -4.9200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2291
    Cell Significance Index: -7.3000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2447
    Cell Significance Index: -25.4800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2585
    Cell Significance Index: -8.2800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2648
    Cell Significance Index: -6.3500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2822
    Cell Significance Index: -6.1800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2899
    Cell Significance Index: -5.8200
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.2995
    Cell Significance Index: -3.7800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3192
    Cell Significance Index: -20.1200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3299
    Cell Significance Index: -18.5100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3505
    Cell Significance Index: -6.9300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.3800
    Cell Significance Index: -9.4800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.4126
    Cell Significance Index: -7.0700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4133
    Cell Significance Index: -14.4800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4181
    Cell Significance Index: -21.7800
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.4505
    Cell Significance Index: -4.9700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.4562
    Cell Significance Index: -4.9700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.4615
    Cell Significance Index: -21.6900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4743
    Cell Significance Index: -13.9700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.4798
    Cell Significance Index: -7.2300
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.5184
    Cell Significance Index: -10.8200
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.5485
    Cell Significance Index: -8.3500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5741
    Cell Significance Index: -21.0800
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.5777
    Cell Significance Index: -7.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Function**: RAP1GAP is a GTPase-activating protein that regulates the activity of Rap1, a small GTPase involved in various cellular processes. 2. **Cellular localization**: RAP1GAP is expressed in a wide range of cell types, including neurons, epithelial cells, and immune cells. 3. **Signaling pathways**: RAP1GAP modulates the signaling pathways of Rap1, which are involved in cell migration, adhesion, and signaling. 4. **Regulation**: RAP1GAP enhances the GTPase activity of Rap1, thereby regulating its signaling pathways. **Pathways and Functions** 1. **Adaptive immune response**: RAP1GAP regulates the signaling pathways of Rap1, which are involved in the adaptive immune response. 2. **Adaptive immune system**: RAP1GAP modulates the activity of Rap1, which is essential for the development and function of the adaptive immune system. 3. **Axon guidance**: RAP1GAP regulates the signaling pathways of Rap1, which are involved in axon guidance and neuronal development. 4. **Neuronal cell body**: RAP1GAP modulates the activity of Rap1, which is essential for the development and function of neuronal cell bodies. 5. **Regulation of microvillus assembly**: RAP1GAP negatively regulates microvillus assembly, which is essential for cell adhesion and signaling. 6. **Regulation of neuron differentiation**: RAP1GAP negatively regulates neuron differentiation, which is essential for the development of the nervous system. **Clinical Significance** 1. **Neurological disorders**: Alterations in RAP1GAP expression or function may contribute to neurological disorders, such as autism spectrum disorder, schizophrenia, and Alzheimer's disease. 2. **Immune system disorders**: RAP1GAP may play a role in the development of immune system disorders, such as autoimmune diseases and immunodeficiency disorders. 3. **Cancer**: RAP1GAP may be involved in the regulation of cell migration and adhesion, which are essential for cancer progression and metastasis. 4. **Thyroid gland epithelial cell proliferation**: RAP1GAP negatively regulates thyroid gland epithelial cell proliferation, which may contribute to thyroid cancer development. In conclusion, RAP1GAP is a critical regulator of Rap1 signaling pathways, which are involved in various cellular processes, including cell migration, adhesion, and signaling. Its dysregulation may contribute to the development of neurological and immune system disorders, as well as cancer. Further research is needed to fully understand the role of RAP1GAP in human disease.

Genular Protein ID: 1469243341

Symbol: RPGP1_HUMAN

Name: Rap1 GTPase-activating protein 1

UniProtKB Accession Codes:

P47736 J3QSS6 O75062 Q5T3S9 Q5T3T4 Q7Z5S8 Q9UQ51

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 2 RefSeq 10 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1904317

Title: Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1.

PubMed ID: 1904317

DOI: 10.1016/0092-8674(91)90555-d

PubMed ID: 9455484

Title: Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

PubMed ID: 9455484

DOI: 10.1093/dnares/4.5.345

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 10476970

Title: Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i).

PubMed ID: 10476970

DOI: 10.1038/23738

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9346962

Title: Human SPA-1 product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2.

PubMed ID: 9346962

DOI: 10.1074/jbc.272.44.28081

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 15141215

Title: The GTPase-activating protein Rap1GAP uses a catalytic asparagine.

PubMed ID: 15141215

DOI: 10.1038/nature02505

PubMed ID: 18309292

Title: The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues.

PubMed ID: 18309292

DOI: 10.1038/emboj.2008.30

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 663
  • Mass: 73361
  • Checksum: 89B307CC67F975DD
  • Sequence:
    • MIEKMQGSRM DEQRCSFPPP LKTEEDYIPY PSVHEVLGRE GPFPLILLPQ FGGYWIEGTN 
HEITSIPETE PLQSPTTKVK LECNPTARIY RKHFLGKEHF NYYSLDAALG HLVFSLKYDV 
IGDQEHLRLL LRTKCRTYHD VIPISCLTEF PNVVQMAKLV CEDVNVDRFY PVLYPKASRL 
IVTFDEHVIS NNFKFGVIYQ KLGQTSEEEL FSTNEESPAF VEFLEFLGQK VKLQDFKGFR 
GGLDVTHGQT GTESVYCNFR NKEIMFHVST KLPYTEGDAQ QLQRKRHIGN DIVAVVFQDE 
NTPFVPDMIA SNFLHAYVVV QAEGGGPDGP LYKVSVTARD DVPFFGPPLP DPAVFRKGPE 
FQEFLLTKLI NAEYACYKAE KFAKLEERTR AALLETLYEE LHIHSQSMMG LGGDEDKMEN 
GSGGGGFFES FKRVIRSRSQ SMDAMGLSNK KPNTVSTSHS GSFAPNNPDL AKAAGISLIV 
PGKSPTRKKS GPFGSRRSSA IGIENIQEVQ EKRESPPAGQ KTPDSGHVSQ EPKSENSSTQ 
SSPEMPTTKN RAETAAQRAE ALKDFSRSSS SASSFASVVE ETEGVDGEDT GLESVSSSGT 
PHKRDSFIYS TWLEDSVSTT SGGSSPGPSR SPHPDAGKLG DPACPEIKIQ LEASEQHMPQ 
LGC

Genular Protein ID: 1016622835

Symbol: X6R8W7_HUMAN

Name: N/A

UniProtKB Accession Codes:

X6R8W7

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 2 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 3 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 748
  • Mass: 81732
  • Checksum: B87DA0F531589E24
  • Sequence:
    • MIEKMQGSRM DEQRCSFPPP LKTEEDYIPY PSVHEVLGRE GPFPLILLPQ FGGYWIEGTN 
HEITSIPETE PLQSPTTKVK LECNPTARIY RKHFLGKEHF NYYSLDAALG HLVFSLKYDV 
IGDQEHLRLL LRTKCRTYHD VIPISCLTEF PNVVQMAKLV CEDVNVDRFY PVLYPKASRL 
IVTFDEHVIS NNFKFGVIYQ KLGQTSEEEL FSTNEESPAF VEFLEFLGQK VKLQDFKGFR 
GGLDVTHGQT GTESVYCNFR NKEIMFHVST KLPYTEGDAQ QLQRKRHIGN DIVAVVFQDE 
NTPFVPDMIA SNFLHAYVVV QAEGGGPDGP LYKVSVTARD DVPFFGPPLP DPAVFRKGPE 
FQEFLLTKLI NAEYACYKAE KFAKLEERTR AALLETLYEE LHIHSQSMMG LGGDEDKMEN 
GSGGGGFFES FKRVIRSRSQ SMDAMGLSNK KPNTVSTSHS GSFAPNNPDL AKAAGISLLI 
PGKSASRFGR RGSAIGIGTV EEVVVRGAAG SGGCLHALFS ARSQDGGHIG DVAPLPPGQA 
PGRAGWSGGS SDGTQHLLWG LSLIVPGKSP TRKKSGPFGS RRSSAIGIEN IQEVQEKRES 
PPAGQKTPDS GHVSQEPKSE NSSTQSSPEM PTTKNRAETA AQRAEALKDF SRSSSSASSF 
ASVVEETEGV DGEDTGLESV SSSGTPHKRD SFIYSTWLED SVSTTSGGSS PGPSRSPHPD 
AGKLGDPACP EIKIQLEASE QHMPQLGC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.