Details for: RAPSN

Gene ID: 5913

Symbol: RAPSN

Ensembl ID: ENSG00000165917

Description: receptor associated protein of the synapse

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 7.9639
    Cell Significance Index: -2.0200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 5.4851
    Cell Significance Index: 59.6300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 4.0615
    Cell Significance Index: -1.6500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 1.6140
    Cell Significance Index: -1.9900
  • Cell Name: muscle precursor cell (CL0000680)
    Fold Change: 1.1315
    Cell Significance Index: 7.7300
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.8573
    Cell Significance Index: 8.9500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.8422
    Cell Significance Index: 20.5500
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 0.7902
    Cell Significance Index: 12.7500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4810
    Cell Significance Index: 10.4200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.4748
    Cell Significance Index: 6.8000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 0.3975
    Cell Significance Index: -0.8700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.2871
    Cell Significance Index: 7.3800
  • Cell Name: tongue muscle cell (CL0002673)
    Fold Change: 0.2818
    Cell Significance Index: 2.1100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.1934
    Cell Significance Index: 6.2000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1666
    Cell Significance Index: 31.7100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0845
    Cell Significance Index: 2.2700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0798
    Cell Significance Index: 4.7900
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: 0.0695
    Cell Significance Index: 1.0400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0628
    Cell Significance Index: 6.2100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0610
    Cell Significance Index: 55.1000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0555
    Cell Significance Index: 2.8900
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 0.0533
    Cell Significance Index: 0.5100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0529
    Cell Significance Index: 10.4900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0502
    Cell Significance Index: 5.4600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0501
    Cell Significance Index: 1.0400
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: 0.0446
    Cell Significance Index: 0.5700
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.0429
    Cell Significance Index: 0.6100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0409
    Cell Significance Index: 0.8700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0380
    Cell Significance Index: 4.4300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0336
    Cell Significance Index: 5.4700
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0328
    Cell Significance Index: 0.4600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0310
    Cell Significance Index: 1.0900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0248
    Cell Significance Index: 1.7200
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: 0.0199
    Cell Significance Index: 0.2600
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.0179
    Cell Significance Index: 0.2300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.0171
    Cell Significance Index: 0.5400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0159
    Cell Significance Index: 2.8700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0127
    Cell Significance Index: 19.5300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0124
    Cell Significance Index: 16.8900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0054
    Cell Significance Index: 0.6700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0044
    Cell Significance Index: 0.2300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0035
    Cell Significance Index: 0.1000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0029
    Cell Significance Index: 5.3400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0016
    Cell Significance Index: 0.2300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0016
    Cell Significance Index: 0.9000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0003
    Cell Significance Index: 0.6500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0008
    Cell Significance Index: -0.3400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0010
    Cell Significance Index: -0.6200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0013
    Cell Significance Index: -0.1000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0014
    Cell Significance Index: -0.0300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0017
    Cell Significance Index: -0.3500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0020
    Cell Significance Index: -0.0500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0023
    Cell Significance Index: -1.6500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0026
    Cell Significance Index: -1.9600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0026
    Cell Significance Index: -0.1200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0030
    Cell Significance Index: -1.0700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0030
    Cell Significance Index: -2.2500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0032
    Cell Significance Index: -0.1600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0034
    Cell Significance Index: -1.5500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0037
    Cell Significance Index: -2.0600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0041
    Cell Significance Index: -0.2500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0049
    Cell Significance Index: -0.2200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0054
    Cell Significance Index: -1.5600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0065
    Cell Significance Index: -0.6600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0071
    Cell Significance Index: -0.8100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0071
    Cell Significance Index: -1.2100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0080
    Cell Significance Index: -0.5700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0099
    Cell Significance Index: -2.0800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0124
    Cell Significance Index: -1.7000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0134
    Cell Significance Index: -1.7300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0159
    Cell Significance Index: -1.8800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0191
    Cell Significance Index: -1.9900
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: -0.0220
    Cell Significance Index: -0.2000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0222
    Cell Significance Index: -1.7600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0224
    Cell Significance Index: -1.0600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0229
    Cell Significance Index: -1.7100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.0234
    Cell Significance Index: -0.5000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0241
    Cell Significance Index: -1.6200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0250
    Cell Significance Index: -0.7000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0257
    Cell Significance Index: -0.3800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0259
    Cell Significance Index: -0.3900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0265
    Cell Significance Index: -1.7100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0273
    Cell Significance Index: -1.5300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0291
    Cell Significance Index: -1.5300
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0321
    Cell Significance Index: -0.4200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0322
    Cell Significance Index: -1.9800
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: -0.0322
    Cell Significance Index: -0.1400
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0337
    Cell Significance Index: -0.8400
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0361
    Cell Significance Index: -1.5700
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: -0.0370
    Cell Significance Index: -0.3900
  • Cell Name: embryonic fibroblast (CL2000042)
    Fold Change: -0.0376
    Cell Significance Index: -0.1800
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0440
    Cell Significance Index: -0.7400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0443
    Cell Significance Index: -1.9600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0464
    Cell Significance Index: -1.2400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0468
    Cell Significance Index: -1.6400
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0486
    Cell Significance Index: -0.7800
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0501
    Cell Significance Index: -1.0200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0509
    Cell Significance Index: -1.6200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0512
    Cell Significance Index: -1.0000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0513
    Cell Significance Index: -1.6800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RAPSN is a membrane-bound protein that exhibits protein-membrane adaptor activity, allowing it to interact with various receptors and ion channels at the postsynaptic specialization membrane. Its expression is widespread, with significant levels found in blood vessel endothelial cells, colon goblet cells, enterocytes, and skeletal muscle satellite stem cells. RAPSN's molecular weight is 43 kDa, and its gene is located on chromosome 19q13.3. **Pathways and Functions:** RAPSN is involved in several key pathways, including: 1. **Acetylcholine receptor binding:** RAPSN interacts with acetylcholine receptors, modulating their activity and contributing to the regulation of neuromuscular junction function. 2. **Chemical synaptic transmission:** RAPSN plays a role in regulating the release and uptake of neurotransmitters, influencing the strength of synaptic transmission. 3. **Cytosol:** RAPSN interacts with cytoskeletal proteins, influencing the organization of the postsynaptic specialization membrane. 4. **Ionotropic glutamate receptor binding:** RAPSN binds to ionotropic glutamate receptors, modulating their activity and contributing to the regulation of excitatory neurotransmission. 5. **Neurotransmitter receptor localization to postsynaptic specialization membrane:** RAPSN facilitates the localization of various receptors and ion channels to the postsynaptic specialization membrane, influencing synaptic function. **Clinical Significance:** Dysregulation of RAPSN has been implicated in various neurological and muscular disorders, including: 1. **Amyotrophic lateral sclerosis (ALS):** Mutations in RAPSN have been associated with ALS, highlighting its role in maintaining motor neuron function. 2. **Myasthenia gravis:** RAPSN's involvement in regulating acetylcholine receptor activity has led to its consideration as a potential therapeutic target for this autoimmune disorder. 3. **Neurodevelopmental disorders:** Abnormal RAPSN expression has been linked to neurodevelopmental disorders, such as autism spectrum disorder and intellectual disability. In conclusion, RAPSN is a critical protein that plays a central role in maintaining postsynaptic specialization and neuromuscular junction function. Its dysregulation has been implicated in various neurological and muscular disorders, highlighting the need for further research into its role in human health and disease.

Genular Protein ID: 3157137857

Symbol: RAPSN_HUMAN

Name: 43 kDa receptor-associated protein of the synapse

UniProtKB Accession Codes:

Q13702 Q8TDF3 Q9BTD9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 20 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8812503

Title: Cloning of cDNA encoding human rapsyn and mapping of the RAPSN gene locus to chromosome 11p11.2-p11.1.

PubMed ID: 8812503

DOI: 10.1006/geno.1996.0409

PubMed ID: 11791205

Title: Rapsyn mutations in humans cause endplate acetylcholine-receptor deficiency and myasthenic syndrome.

PubMed ID: 11791205

DOI: 10.1086/339465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19158078

Title: Control of rapsyn stability by the CUL-3-containing E3 ligase complex.

PubMed ID: 19158078

DOI: 10.1074/jbc.m808230200

PubMed ID: 12730725

Title: Identification of pathogenic mutations in the human rapsyn gene.

PubMed ID: 12730725

DOI: 10.1007/s10038-003-0005-7

PubMed ID: 12929188

Title: Rapsyn mutations in myasthenic syndrome due to impaired receptor clustering.

PubMed ID: 12929188

DOI: 10.1002/mus.10433

PubMed ID: 12796535

Title: Rapsyn N88K is a frequent cause of congenital myasthenic syndromes in European patients.

PubMed ID: 12796535

DOI: 10.1212/01.wnl.0000072262.14931.80

PubMed ID: 14504330

Title: Rapsyn mutations in hereditary myasthenia: distinct early- and late-onset phenotypes.

PubMed ID: 14504330

DOI: 10.1212/01.wnl.0000085865.55513.ae

PubMed ID: 15036330

Title: Novel truncating RAPSN mutations causing congenital myasthenic syndrome responsive to 3,4-diaminopyridine.

PubMed ID: 15036330

DOI: 10.1016/j.nmd.2003.11.004

PubMed ID: 15328566

Title: Congenital myasthenic syndrome due to rapsyn deficiency: three cases with arthrogryposis and bulbar symptoms.

PubMed ID: 15328566

DOI: 10.1055/s-2004-820993

PubMed ID: 16931511

Title: Impaired receptor clustering in congenital myasthenic syndrome with novel RAPSN mutations.

PubMed ID: 16931511

DOI: 10.1212/01.wnl.0000233837.79459.40

PubMed ID: 17594401

Title: Congenital myasthenic syndrome caused by two non-N88K rapsyn mutations.

PubMed ID: 17594401

DOI: 10.1111/j.1399-0004.2007.00824.x

PubMed ID: 18179903

Title: Mutation analysis of CHRNA1, CHRNB1, CHRND, and RAPSN genes in multiple pterygium syndrome/fetal akinesia patients.

PubMed ID: 18179903

DOI: 10.1016/j.ajhg.2007.09.016

PubMed ID: 18252226

Title: Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders.

PubMed ID: 18252226

DOI: 10.1016/j.ajhg.2007.11.006

Sequence Information:

  • Length: 412
  • Mass: 46328
  • Checksum: D17AC566700F5AAF
  • Sequence:
    • MGQDQTKQQI EKGLQLYQSN QTEKALQVWT KVLEKSSDLM GRFRVLGCLV TAHSEMGRYK 
EMLKFAVVQI DTARELEDAD FLLESYLNLA RSNEKLCEFH KTISYCKTCL GLPGTRAGAQ 
LGGQVSLSMG NAFLGLSVFQ KALESFEKAL RYAHNNDDAM LECRVCCSLG SFYAQVKDYE 
KALFFPCKAA ELVNNYGKGW SLKYRAMSQY HMAVAYRLLG RLGSAMECCE ESMKIALQHG 
DRPLQALCLL CFADIHRSRG DLETAFPRYD SAMSIMTEIG NRLGQVQALL GVAKCWVARK 
ALDKALDAIE RAQDLAEEVG NKLSQLKLHC LSESIYRSKG LQRELRAHVV RFHECVEETE 
LYCGLCGESI GEKNSRLQAL PCSHIFHLRC LQNNGTRSCP NCRRSSMKPG FV

Genular Protein ID: 74709381

Symbol: A0A0S2Z4M9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0S2Z4M9

Database IDs:

ARBA 6 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 4 ExpressionAtlas 1 GO 6 Gene3D 2 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 2 Pfam 3 RefSeq 1 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 353
  • Mass: 39912
  • Checksum: 79A95D25A1FAA69A
  • Sequence:
    • MGQDQTKQQI EKGLQLYQSN QTEKALQVWT KVLEKSSDLM GRFRVLGCLV TAHSEMGRYK 
EMLKFAVVQI DTARELEDAD FLLESYLNLA RSNEKLCEFH KTISYCKTCL GLPGTRAGAQ 
LGGQVSLSMG NAFLGLSVFQ KALESFEKAL RYAHNNDDAM LECRVCCSLG SFYAQVKDYE 
KALFFPCKAA ELVNNYGKGW SLKYRAMSQY HMAVAYRLLG RLGSAMECCE ESMKIALQHG 
DRPLQALCLL CFADIHRSRG DLELSQLKLH CLSESIYRSK GLQRELRAHV VRFHECVEET 
ELYCGLCGES IGEKNSRLQA LPCSHIFHLR CLQNNGTRSC PNCRRSSMKP GFV

Genular Protein ID: 3088430214

Symbol: A0A0S2Z4A6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0S2Z4A6

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 2 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 3 RefSeq 1 SMART 2 SUPFAM 2

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 394
  • Mass: 44404
  • Checksum: C0B467EAA33DB441
  • Sequence:
    • MGQDQTKQQI EKGLQLYQSN QTEKALQVWT KVLEKSSDLM GRFRVLGCLV TAHSEMGRYK 
EMLKFAVVQI DTARELEDAD FLLESYLNLA RSNEKLCEFH KTISYCKTCL GLPGTRAGAQ 
LGGQVSLSMG NAFLGLSVFQ KALESFEKAL RYAHNNDDAM LECRVCCSLG SFYAQVKDYE 
KALFFPCKAA ELVNNYGKGW SLKYRAMSQY HMAVAYRLLG RLGSAMECCE ESMKIALQHG 
DRPLQALCLL CFADIHRSRG DLETAFPRYD SAMSIMTEIG NRLGQVQALL GVAKCWVARK 
ALDKLSQLKL HCLSESIYRS KGLQRELRAH VVRFHECVEE TELYCGLCGE SIGEKNSRLQ 
ALPCSHIFHL RCLQNNGTRS CPNCRRSSMK PGFV

Genular Protein ID: 949084418

Symbol: A0A0S2Z4A2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0S2Z4A2

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 2 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 3 RefSeq 1 SMART 2 SUPFAM 2

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 371
  • Mass: 41836
  • Checksum: DBA1D5716DA26BD0
  • Sequence:
    • MGQDQTKQQI EKGLQLYQSN QTEKALQVWT KVLEKSSDLM GRFRVLGCLV TAHSEMGRYK 
EMLKFAVVQI DTARELEDAD FLLESYLNLA RSNEKLCEFH KTISYCKTCL GLPGTRAGAQ 
LGGQVSLSMG NAFLGLSVFQ KALESFEKAL RYAHNNDDAM LECRVCCSLG SFYAQVKDYE 
KALFFPCKAA ELVNNYGKGW SLKYRAMSQY HMAVAYRLLG RLGSAMECCE ESMKIALQHG 
DRPLQALCLL CFADIHRSRG DLEALDAIER AQDLAEEVGN KLSQLKLHCL SESIYRSKGL 
QRELRAHVVR FHECVEETEL YCGLCGESIG EKNSRLQALP CSHIFHLRCL QNNGTRSCPN 
CRRSSMKPGF V

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.