Details for: RGS3

Gene ID: 5998

Symbol: RGS3

Ensembl ID: ENSG00000138835

Description: regulator of G protein signaling 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 153.9745
    Cell Significance Index: -23.9500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 91.2305
    Cell Significance Index: -23.1400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 51.5437
    Cell Significance Index: -20.9400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 50.1776
    Cell Significance Index: -23.6900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 22.0059
    Cell Significance Index: -21.0100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 19.5181
    Cell Significance Index: -24.0700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.4883
    Cell Significance Index: -20.0600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.4530
    Cell Significance Index: -19.8200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.0060
    Cell Significance Index: -23.7000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 2.4114
    Cell Significance Index: 458.9000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 2.0018
    Cell Significance Index: 256.6200
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 1.9105
    Cell Significance Index: 11.8200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.5606
    Cell Significance Index: 81.2900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.3943
    Cell Significance Index: 107.0000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.3448
    Cell Significance Index: 14.6200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.1896
    Cell Significance Index: 17.1100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.1655
    Cell Significance Index: 115.3000
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.1385
    Cell Significance Index: 9.0900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.0868
    Cell Significance Index: 29.1200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0359
    Cell Significance Index: 935.3800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.9701
    Cell Significance Index: 20.3100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.9656
    Cell Significance Index: 54.1900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8122
    Cell Significance Index: 161.1800
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.6986
    Cell Significance Index: 6.3400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6803
    Cell Significance Index: 110.6500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6203
    Cell Significance Index: 67.4700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.4660
    Cell Significance Index: 6.8800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4205
    Cell Significance Index: 19.0600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3961
    Cell Significance Index: 23.7800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.3640
    Cell Significance Index: 12.6500
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.2648
    Cell Significance Index: 1.6000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2559
    Cell Significance Index: 5.5500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2502
    Cell Significance Index: 7.2100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2204
    Cell Significance Index: 5.5100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1851
    Cell Significance Index: 84.0200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1313
    Cell Significance Index: 9.0800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1281
    Cell Significance Index: 69.9700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0901
    Cell Significance Index: 16.2500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0864
    Cell Significance Index: 11.8600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0464
    Cell Significance Index: 9.3100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0424
    Cell Significance Index: 29.3100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0286
    Cell Significance Index: 1.4900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0275
    Cell Significance Index: 0.4600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0264
    Cell Significance Index: 3.2400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0263
    Cell Significance Index: 16.7300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0227
    Cell Significance Index: 8.1300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0206
    Cell Significance Index: 0.7300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0068
    Cell Significance Index: 0.1900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0049
    Cell Significance Index: 9.2400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0009
    Cell Significance Index: -1.6100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0034
    Cell Significance Index: -1.4900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0083
    Cell Significance Index: -6.0800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0092
    Cell Significance Index: -14.2000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0103
    Cell Significance Index: -7.8000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0136
    Cell Significance Index: -18.4400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0166
    Cell Significance Index: -0.4800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0331
    Cell Significance Index: -24.5500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0402
    Cell Significance Index: -25.1200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0429
    Cell Significance Index: -24.2200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.0532
    Cell Significance Index: -0.9400
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: -0.0586
    Cell Significance Index: -0.2600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0592
    Cell Significance Index: -10.1100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0671
    Cell Significance Index: -7.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0675
    Cell Significance Index: -7.0300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0687
    Cell Significance Index: -19.7700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0699
    Cell Significance Index: -8.2400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0804
    Cell Significance Index: -8.2100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0817
    Cell Significance Index: -1.7400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.0836
    Cell Significance Index: -1.0700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1022
    Cell Significance Index: -14.8500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.1235
    Cell Significance Index: -1.9100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1277
    Cell Significance Index: -14.6300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1302
    Cell Significance Index: -27.4200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1494
    Cell Significance Index: -19.3000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1633
    Cell Significance Index: -5.2300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2072
    Cell Significance Index: -10.8800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2096
    Cell Significance Index: -16.6000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2150
    Cell Significance Index: -13.2200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2187
    Cell Significance Index: -10.2800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2202
    Cell Significance Index: -15.5700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2209
    Cell Significance Index: -16.4600
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.2342
    Cell Significance Index: -3.2900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2377
    Cell Significance Index: -14.9800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2445
    Cell Significance Index: -6.4300
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.2706
    Cell Significance Index: -2.3000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2820
    Cell Significance Index: -17.2900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2894
    Cell Significance Index: -18.6700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2972
    Cell Significance Index: -7.6400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3126
    Cell Significance Index: -4.2700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3261
    Cell Significance Index: -4.6700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3291
    Cell Significance Index: -22.1300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3745
    Cell Significance Index: -11.0300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.4541
    Cell Significance Index: -21.1700
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.4752
    Cell Significance Index: -2.8200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.4806
    Cell Significance Index: -5.4600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4838
    Cell Significance Index: -21.4000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.5104
    Cell Significance Index: -13.0400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.5170
    Cell Significance Index: -13.8300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.5339
    Cell Significance Index: -8.0000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.5419
    Cell Significance Index: -14.7500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression Pattern:** RGS3 is significantly expressed in various cell types, including pulmonary interstitial fibroblasts, preosteoblasts, cardiac myocytes, and endothelial cells, suggesting its widespread involvement in different tissues and organs. 2. **Protein Structure:** RGS3 is a member of the regulator of G-protein signaling (RGS) family, which consists of proteins that regulate the activity of G-protein coupled receptors. The protein structure of RGS3 contains a GTPase-activating protein (GAP) domain, which is essential for its function. 3. **Function:** RGS3 acts as a negative regulator of GPCR signaling by accelerating the GTP hydrolysis of G-proteins, thereby reducing the duration of signal transmission. This function is critical for maintaining homeostasis and preventing excessive signaling. **Pathways and Functions:** 1. **GPCR Signaling Pathway:** RGS3 regulates the activity of GPCRs by accelerating the GTP hydrolysis of G-proteins, which in turn modulates the signaling output of these receptors. 2. **Gα(i) and Gα(q) Signaling Events:** RGS3 has been shown to regulate the activity of Gα(i) and Gα(q) proteins, which are essential for various signaling pathways, including those involved in cardiovascular and immune responses. 3. **Negative Regulation of Signal Transduction:** RGS3 acts as a negative regulator of signal transduction by accelerating the GTP hydrolysis of G-proteins, thereby reducing the duration of signal transmission. 4. **Regulation of G-Protein Coupled Receptor Signaling Pathway:** RGS3 regulates the activity of GPCRs by modulating the signaling output of these receptors, which is essential for maintaining homeostasis and preventing excessive signaling. **Clinical Significance:** 1. **Cardiovascular Diseases:** RGS3 has been implicated in the regulation of cardiovascular signaling pathways, and alterations in its expression or function have been associated with various cardiovascular diseases, including hypertension and cardiac arrhythmias. 2. **Respiratory Diseases:** RGS3 has been shown to regulate the activity of GPCRs involved in respiratory signaling pathways, and alterations in its expression or function have been associated with respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD). 3. **Neurological Diseases:** RGS3 has been implicated in the regulation of GPCR signaling pathways in the nervous system, and alterations in its expression or function have been associated with various neurological diseases, including Parkinson's disease and Alzheimer's disease. 4. **Cancer:** RGS3 has been shown to regulate the activity of GPCRs involved in cancer signaling pathways, and alterations in its expression or function have been associated with various types of cancer, including breast and lung cancer. In conclusion, RGS3 plays a crucial role in regulating G-protein coupled receptor signaling pathways, and its dysregulation has been implicated in various diseases, including cardiovascular, respiratory, and neurological disorders. Further studies are necessary to fully understand the mechanisms of RGS3 and its clinical significance in human diseases.

Genular Protein ID: 3168352862

Symbol: RGS3_HUMAN

Name: Regulator of G-protein signaling 3

UniProtKB Accession Codes:

P49796 A6NHA0 A8K0V1 B3KUB2 Q5VXB8 Q5VXC1 Q5VZ05 Q5VZ06 Q6ZRM5 Q8IUQ1 Q8NC47 Q8NFN4 Q8NFN5 Q8NFN6 Q8TD59 Q8TD68 Q8WV02 Q8WXA0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 3 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 20 Ensembl 7 EvolutionaryTrace 1 ExpressionAtlas 1 GO 8 Gene3D 5 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 8 RNAct 1 Reactome 2 RefSeq 20 SMART 3 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8602223

Title: Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family.

PubMed ID: 8602223

DOI: 10.1038/379742a0

PubMed ID: 12036301

Title: Additional 5' exons in the RGS3 locus generate multiple mRNA transcripts, one of which accounts for the origin of human PDZ-RGS3.

PubMed ID: 12036301

DOI: 10.1006/geno.2002.6773

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9858594

Title: RGS3 inhibits G protein-mediated signaling via translocation to the membrane and binding to Galpha11.

PubMed ID: 9858594

DOI: 10.1128/mcb.19.1.714

PubMed ID: 10749886

Title: Regulator of G protein signaling RGS3T is localized to the nucleus and induces apoptosis.

PubMed ID: 10749886

DOI: 10.1074/jbc.m910079199

PubMed ID: 11294858

Title: Regulator of G-protein signaling 3 (RGS3) inhibits G-beta1/gamma2-induced inositol phosphate production, mitogen-activated protein kinase activation, and Akt activation.

PubMed ID: 11294858

DOI: 10.1074/jbc.m100089200

PubMed ID: 16884686

Title: Identification and Herc5-mediated ISGylation of novel target proteins.

PubMed ID: 16884686

DOI: 10.1016/j.bbrc.2006.07.076

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

  • Length: 1198
  • Mass: 132336
  • Checksum: E615DA49022EFFE4
  • Sequence:
    • MPVIPALWEV EMGRSQGQEI ETILANRSHS DSTPLPNFLS GSHRPECCTC RLLTASGAQD 
SLPFGRRLYS GPWRSCEEVC HVSVLSVLST SCGLSLSLPI FPGWMEWLSP DIALPRRDEW 
TQTSPARKRI THAKVQGAGQ LRLSIDAQDR VLLLHIIEGK GLISKQPGTC DPYVKISLIP 
EDSRLRHQKT QTVPDCRDPA FHEHFFFPVQ EEDDQKRLLV TVWNRASQSR QSGLIGCMSF 
GVKSLLTPDK EISGWYYLLG EHLGRTKHLK VARRRLRPLR DPLLRMPGGG DTENGKKLKI 
TIPRGKDGFG FTICCDSPVR VQAVDSGGPA ERAGLQQLDT VLQLNERPVE HWKCVELAHE 
IRSCPSEIIL LVWRMVPQVK PGPDGGVLRR ASCKSTHDLQ SPPNKREKNC THGVQARPEQ 
RHSCHLVCDS SDGLLLGGWE RYTEVAKRGG QHTLPALSRA TAPTDPNYII LAPLNPGSQL 
LRPVYQEDTI PEESGSPSKG KSYTGLGKKS RLMKTVQTMK GHGNYQNCPV VRPHATHSSY 
GTYVTLAPKV LVFPVFVQPL DLCNPARTLL LSEELLLYEG RNKAAEVTLF AYSDLLLFTK 
EDEPGRCDVL RNPLYLQSVK LQEGSSEDLK FCVLYLAEKA ECLFTLEAHS QEQKKRVCWC 
LSENIAKQQQ LAASPPDSKM FETEADEKRE MALEEGKGPG AEDSPPSKEP SPGQELPPGQ 
DLPPNKDSPS GQEPAPSQEP LSSKDSATSE GSPPGPDAPP SKDVPPCQEP PPAQDLSPCQ 
DLPAGQEPLP HQDPLLTKDL PAIQESPTRD LPPCQDLPPS QVSLPAKALT EDTMSSGDLL 
AATGDPPAAP RPAFVIPEVR LDSTYSQKAG AEQGCSGDEE DAEEAEEVEE GEEGEEDEDE 
DTSDDNYGER SEAKRSSMIE TGQGAEGGLS LRVQNSLRRR THSEGSLLQE PRGPCFASDT 
TLHCSDGEGA ASTWGMPSPS TLKKELGRNG GSMHHLSLFF TGHRKMSGAD TVGDDDEASR 
KRKSKNLAKD MKNKLGIFRR RNESPGAPPA GKADKMMKSF KPTSEEALKW GESLEKLLVH 
KYGLAVFQAF LRTEFSEENL EFWLACEDFK KVKSQSKMAS KAKKIFAEYI AIQACKEVNL 
DSYTREHTKD NLQSVTRGCF DLAQKRIFGL MEKDSYPRFL RSDLYLDLIN QKKMSPPL

Genular Protein ID: 1301095048

Symbol: B3KWG8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KWG8

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 5 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 6 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 2 SAM 2 SMART 3 SUPFAM 4

Sequence Information:

  • Length: 1088
  • Mass: 120200
  • Checksum: 0ABAE7F29B9F783C
  • Sequence:
    • MPRTGFCCFT VSLFVWMDMS MCVSLSRCVC VYVSIHPPQC LNSLLVIEGK GLISKQPGTC 
DPYVKISLIP EDSRLRHQKT QTVPDCRDPA FHEHFFFPVQ EEDDQKRLLV TVWNRASQSR 
QSGLIGCMSF GVKSLLTPDK EISGWYYLLG EHLGRTKHLK VARRRLRPLR DPLLRMPGGG 
DTENGKKLKI TIPRGKDGFG FTICCDSPVR VQAVDSGGPA ERAGLQQLDT VLQLNERPVE 
HWKCVELAHE IRSCPSEIIL LVWRMVPQVK PGPDGGVLRR ASCKSTHDLQ SPPNKREKNC 
THGVQARPEQ RHSCHLVCDS SDGLLLGGWE RYTEVAKRGG QHTLPALSRA TAPTDPNYII 
LAPLNPGSQL LRPVYQEYTI PEESGSPSKG KSYTGLGKKS RLMKTVQTMK GHGNYQNCPV 
VRPHATHSSY GTYVTLAPKV LVFPVFVQPL DLCNPARTLL LSEGLLLYEG RNKAAEVTLF 
AYSDLLLFTK EDEPGRCDVL RNPLYLQSVK LQEGSSEDLK FCVLYLAEKA ECLFTLEAHS 
QEQKKRVCWC LSENIAKQQQ LAASPPDSKM FETEADEKRE MALEEGKGPG AEDSPPSKEP 
SPGQELPPGQ DLPPNKDSPS GQEPAPSQEP LSSKDSATSE GSPPGPDAPP SKDVPPCQEP 
PPAQDLSPCQ DLPAGQEPLP HQDPLLTKDL PAIQESPTRD LPPCQDLPPS QVSLPAKALT 
EDTMSSGDLL AATGDPPAAP RPAFVIPEVR LDSTYSQKAG AEQGCSGDEE DAEEAEEVEE 
GEEGEEDEDE DTSDDNYGER SEAKRSSMIE TGQGAEGGLS LRVQNSLRRR THSEGSLLQE 
PRGPCFASDT TLHCSDGEGA ASTWGMPSPS TLKKELGRNG GSMHHLSLFF TGHRKMSGAD 
TVGDDDEASR KRKSKNLAKD MKNKLGIFRR RNESPGAPPA GKADKMMKSF KPTSEEALKW 
GESLEKLLVH KYGLAVFQAF LRTEFSEENL EFWLACEDFK KVKSQSKMAS KAKKIFAEYI 
AIQACKEVNL DSYTREHTKD NLQSVTRGCF DLAQKRIFGL MEKDSYPRFL RSDLYLDLIN 
QKKMSPPL

Genular Protein ID: 3228257788

Symbol: H7BXY1_HUMAN

Name: N/A

UniProtKB Accession Codes:

H7BXY1

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 2 Gene3D 2 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 2 SAM 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

Sequence Information:

  • Length: 168
  • Mass: 19456
  • Checksum: 290452760ABF9C72
  • Sequence:
    • MKNKLGIFRR RNESPGAPPA GKADKMMKSF KPTSEEALKW GESLEKLLVH KYGLAVFQAF 
LRTEFSEENL EFWLACEDFK KVKSQSKMAS KAKKIFAEYI AIQACKEVNL DSYTREHTKD 
NLQSVTRGCF DLAQKRIFGL MEKDSYPRFL RSDLYLDLIN QKKMSPPL

Genular Protein ID: 262597269

Symbol: B3KVT7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KVT7

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 2 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 519
  • Mass: 56601
  • Checksum: C7CFE3FFCB43E5A8
  • Sequence:
    • MFETEADEKR EMALEEGKGP GAEDSPPSKE PSPGQELPPG QDLPPNKDSP SGQEPAPSQE 
PLSSKDSATS EGSPPGPDAP PSKDVPPCQE PPPAQDLSPC QDLPAGQEPL PHQDPLLTKD 
LPAIQESPTR DLPPCQDLPP SQVSLPAKAL TEDTMSSGDL LAATGDPPAA PRPAFVIPEV 
RLDSTYSQKA GAEQGCSGDE EDAEEAEEVE EGEEGEEDED EDTSDDNYGE RSEAKRSSMI 
ETGQGAEGGL SLRVQNSLRR RTHSEGSLLQ EPRGPCFASD TTLHCSDGEG AASTWGMPSP 
STLKKELGRN GGSMHHLSLF FTGHRKMSGA DTVGDDDEAS RKRKSKNLAK DMKNKLGIFR 
RRNESPGAPP AGKADKMMKS FKPTSKEALK WGESLEKLLV HKYGLAVFQA FLRTEFSEEN 
LEFWLACEDF KKVKSQSKMA SKAKKIFAEY IAIQACKEVN LDSYTREHTK DNLQSVTRGC 
FDLAQKRIFG LMEKDSYPRF LRSDLYLDLI NQKKMSPPL

Genular Protein ID: 1208322531

Symbol: Q53GP3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53GP3

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 2 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 2

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 415
  • Mass: 45848
  • Checksum: C9926F3DC739CD98
  • Sequence:
    • ITIPRGKDGF GFTICCDSPV RVQAVDSGGP AERAGLQQLD TVLQLNERPV EHWKCAELAH 
EIRSCPSEII LLVWRMVPQV KPGPDGGVLR RASCKSTHDL QSPPNKREKN CTHGVQARPE 
QRHSCHLVCD SSDGLLLGGW ERYTEVAKRG GQHTLPALSR ATAPTDPNYI ILAPLNPGSQ 
LLRPVYQEDT IPEESGSPSK GKSYTGLGKK SRLMKTVQTM KGHGNYQNCP VVRPHATHSS 
YGTYVTLAPK VLVFPVFVQP LDLCNPARTL LLSEELLLYE GRNKAAEVTL FAYSDLLLFT 
KEDEPGRCDV LRNPLYLRSV KLQEGSSEDL KFCVLYLAEK AECLFTLEAH SQEQKKRVCW 
CLSENIAKQQ QLAASPPDSK KLHPFGSLQQ EMGPVNSTNA TQDRSFTSPG QTLIG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.