Details for: ROBO2

Gene ID: 6092

Symbol: ROBO2

Ensembl ID: ENSG00000185008

Description: roundabout guidance receptor 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 279.3923
    Cell Significance Index: -115.1000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 234.0636
    Cell Significance Index: -95.0900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 14.7995
    Cell Significance Index: -32.3900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 10.4576
    Cell Significance Index: 250.8000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 9.7681
    Cell Significance Index: 3503.6500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 9.1426
    Cell Significance Index: 513.0400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 9.0204
    Cell Significance Index: 341.5800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 8.5725
    Cell Significance Index: 379.1800
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 7.2661
    Cell Significance Index: 75.6900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 7.2186
    Cell Significance Index: 206.0000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 6.5434
    Cell Significance Index: 402.1900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 4.6703
    Cell Significance Index: 91.1500
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 4.5788
    Cell Significance Index: 59.3800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 4.0829
    Cell Significance Index: 2823.8600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.8602
    Cell Significance Index: 107.8800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 2.2252
    Cell Significance Index: 149.6200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.1485
    Cell Significance Index: 430.9800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.3775
    Cell Significance Index: 273.3700
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 1.3192
    Cell Significance Index: 16.4500
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 1.0310
    Cell Significance Index: 8.5100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.5925
    Cell Significance Index: 112.7700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.4832
    Cell Significance Index: 8.2800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3729
    Cell Significance Index: 336.7000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.2554
    Cell Significance Index: 5.0500
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: 0.1482
    Cell Significance Index: 1.8700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1452
    Cell Significance Index: 65.8800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0879
    Cell Significance Index: 48.0000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0310
    Cell Significance Index: 42.1700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0036
    Cell Significance Index: -2.2600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0092
    Cell Significance Index: -17.2600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0307
    Cell Significance Index: -47.2100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0397
    Cell Significance Index: -73.2600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0505
    Cell Significance Index: -37.4100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0961
    Cell Significance Index: -54.1900
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1083
    Cell Significance Index: -1.1800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1229
    Cell Significance Index: -76.7400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1463
    Cell Significance Index: -107.2800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1579
    Cell Significance Index: -16.4400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.1711
    Cell Significance Index: -75.6300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1729
    Cell Significance Index: -130.8600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.3081
    Cell Significance Index: -50.1200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.3193
    Cell Significance Index: -6.4100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.3214
    Cell Significance Index: -92.4800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4062
    Cell Significance Index: -13.3000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.4413
    Cell Significance Index: -51.4300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.4672
    Cell Significance Index: -84.2200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.4696
    Cell Significance Index: -6.7300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.4733
    Cell Significance Index: -99.6800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.5080
    Cell Significance Index: -86.7500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.5106
    Cell Significance Index: -11.1800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.5469
    Cell Significance Index: -54.1000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5642
    Cell Significance Index: -34.5900
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.5757
    Cell Significance Index: -7.6800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.5763
    Cell Significance Index: -83.7700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.6551
    Cell Significance Index: -71.2500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.6596
    Cell Significance Index: -90.5800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.6628
    Cell Significance Index: -23.2900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7297
    Cell Significance Index: -23.2400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.7355
    Cell Significance Index: -15.6100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.7463
    Cell Significance Index: -91.7700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.8337
    Cell Significance Index: -106.8800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.8554
    Cell Significance Index: -110.5100
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.9009
    Cell Significance Index: -6.5500
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.9438
    Cell Significance Index: -11.9100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -1.0115
    Cell Significance Index: -45.8500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -1.0263
    Cell Significance Index: -117.5800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -1.1247
    Cell Significance Index: -114.8900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -1.1326
    Cell Significance Index: -129.2900
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.1572
    Cell Significance Index: -13.5000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -1.1669
    Cell Significance Index: -33.6200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -1.2256
    Cell Significance Index: -63.8400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -1.2448
    Cell Significance Index: -88.0400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -1.3690
    Cell Significance Index: -94.6700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.3944
    Cell Significance Index: -110.4400
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -1.4215
    Cell Significance Index: -17.0000
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -1.4231
    Cell Significance Index: -13.5400
  • Cell Name: neuron (CL0000540)
    Fold Change: -1.4506
    Cell Significance Index: -13.7500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.4749
    Cell Significance Index: -109.9300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.4854
    Cell Significance Index: -77.9900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.5080
    Cell Significance Index: -90.5300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.5130
    Cell Significance Index: -116.1100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.5310
    Cell Significance Index: -38.2700
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -1.5571
    Cell Significance Index: -10.5500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.6259
    Cell Significance Index: -56.9600
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -1.6458
    Cell Significance Index: -19.9500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.7427
    Cell Significance Index: -21.6200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -1.7703
    Cell Significance Index: -44.1600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -1.8269
    Cell Significance Index: -117.8600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -1.9255
    Cell Significance Index: -41.6000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.9346
    Cell Significance Index: -67.2300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.9841
    Cell Significance Index: -92.5100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -2.1521
    Cell Significance Index: -135.6400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -2.2913
    Cell Significance Index: -107.6900
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -2.3881
    Cell Significance Index: -75.5300
  • Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
    Fold Change: -2.5630
    Cell Significance Index: -26.3500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -2.5758
    Cell Significance Index: -53.7600
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: -2.6441
    Cell Significance Index: -20.2800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -2.6550
    Cell Significance Index: -85.0400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -2.6682
    Cell Significance Index: -44.6600
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -2.8328
    Cell Significance Index: -56.4900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ROBO2 is a transmembrane protein that belongs to the Roundabout receptor family. It binds to Slit ligands, which are secreted proteins that regulate axon guidance and neuronal migration. The ROBO2-Slit interaction is essential for the proper development of the nervous system, including the formation of axons, dendrites, and synapses. ROBO2 is also involved in the regulation of other cellular processes, such as cell-cell adhesion, chemotaxis, and the negative regulation of synapse assembly. **Pathways and Functions:** ROBO2 is involved in several key developmental pathways, including: 1. **Axon Guidance:** ROBO2 plays a crucial role in regulating axon guidance, which is essential for the formation of neural connections and the establishment of proper neuronal migration patterns. 2. **Cell-Cell Adhesion:** ROBO2 interacts with Slit ligands to regulate cell-cell adhesion, which is essential for the formation of neural tissue and the maintenance of tissue structure. 3. **Chemotaxis:** ROBO2 is involved in the regulation of chemotaxis, which is the movement of cells in response to chemical gradients. 4. **Synapse Assembly:** ROBO2 negatively regulates synapse assembly, which is essential for the formation of functional neural connections. **Clinical Significance:** Dysregulation of ROBO2 has been implicated in several neurological disorders, including: 1. **Autism Spectrum Disorder (ASD):** Mutations in the ROBO2 gene have been associated with ASD, highlighting the importance of ROBO2 in regulating axon guidance and neuronal migration. 2. **Schizophrenia:** ROBO2 has been implicated in the regulation of synaptic plasticity and neuronal migration, which are critical for the development of schizophrenia. 3. **Neuropathic Pain:** ROBO2 is involved in the regulation of pain transmission, and dysregulation of ROBO2 has been implicated in the development of neuropathic pain. In conclusion, ROBO2 is a critical gene involved in axon guidance, cell-cell adhesion, chemotaxis, and synapse assembly. Dysregulation of ROBO2 has been implicated in several neurological disorders, highlighting the importance of this gene in maintaining proper neural development and function. Further research is needed to fully elucidate the role of ROBO2 in human disease and to develop therapeutic strategies for the treatment of ROBO2-related disorders.

Genular Protein ID: 3926584561

Symbol: ROBO2_HUMAN

Name: Roundabout homolog 2

UniProtKB Accession Codes:

Q9HCK4 O43608 Q19AB4 Q19AB5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 4 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 20 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 30 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 6 RefSeq 5 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 16829019

Title: Isolation and differential expression of two isoforms of the ROBO2/Robo2 axon guidance receptor gene in humans and mice.

PubMed ID: 16829019

DOI: 10.1016/j.ygeno.2006.05.011

PubMed ID: 10997877

Title: Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10997877

DOI: 10.1093/dnares/7.4.271

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9458045

Title: Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors.

PubMed ID: 9458045

DOI: 10.1016/s0092-8674(00)80915-0

PubMed ID: 10102268

Title: Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.

PubMed ID: 10102268

DOI: 10.1016/s0092-8674(00)80590-5

PubMed ID: 11404413

Title: Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance.

PubMed ID: 11404413

DOI: 10.1523/jneurosci.21-12-04281.2001

PubMed ID: 17357069

Title: Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux.

PubMed ID: 17357069

DOI: 10.1086/512735

Sequence Information:

  • Length: 1378
  • Mass: 151200
  • Checksum: 60F7CE3E53622B50
  • Sequence:
    • MSLLMFTQLL LCGFLYVRVD GSRLRQEDFP PRIVEHPSDV IVSKGEPTTL NCKAEGRPTP 
TIEWYKDGER VETDKDDPRS HRMLLPSGSL FFLRIVHGRR SKPDEGSYVC VARNYLGEAV 
SRNASLEVAL LRDDFRQNPT DVVVAAGEPA ILECQPPRGH PEPTIYWKKD KVRIDDKEER 
ISIRGGKLMI SNTRKSDAGM YTCVGTNMVG ERDSDPAELT VFERPTFLRR PINQVVLEEE 
AVEFRCQVQG DPQPTVRWKK DDADLPRGRY DIKDDYTLRI KKTMSTDEGT YMCIAENRVG 
KMEASATLTV RAPPQFVVRP RDQIVAQGRT VTFPCETKGN PQPAVFWQKE GSQNLLFPNQ 
PQQPNSRCSV SPTGDLTITN IQRSDAGYYI CQALTVAGSI LAKAQLEVTD VLTDRPPPII 
LQGPANQTLA VDGTALLKCK ATGDPLPVIS WLKEGFTFPG RDPRATIQEQ GTLQIKNLRI 
SDTGTYTCVA TSSSGETSWS AVLDVTESGA TISKNYDLSD LPGPPSKPQV TDVTKNSVTL 
SWQPGTPGTL PASAYIIEAF SQSVSNSWQT VANHVKTTLY TVRGLRPNTI YLFMVRAINP 
QGLSDPSPMS DPVRTQDISP PAQGVDHRQV QKELGDVLVR LHNPVVLTPT TVQVTWTVDR 
QPQFIQGYRV MYRQTSGLQA TSSWQNLDAK VPTERSAVLV NLKKGVTYEI KVRPYFNEFQ 
GMDSESKTVR TTEEAPSAPP QSVTVLTVGS YNSTSISVSW DPPPPDHQNG IIQEYKIWCL 
GNETRFHINK TVDAAIRSVI IGGLFPGIQY RVEVAASTSA GVGVKSEPQP IIIGRRNEVV 
ITENNNSITE QITDVVKQPA FIAGIGGACW VILMGFSIWL YWRRKKRKGL SNYAVTFQRG 
DGGLMSNGSR PGLLNAGDPS YPWLADSWPA TSLPVNNSNS GPNEIGNFGR GDVLPPVPGQ 
GDKTATMLSD GAIYSSIDFT TKTSYNSSSQ ITQATPYATT QILHSNSIHE LAVDLPDPQW 
KSSIQQKTDL MGFGYSLPDQ NKGNNGGKGG KKKKNKNSSK PQKNNGSTWA NVPLPPPPVQ 
PLPGTELEHY AVEQQENGYD SDSWCPPLPV QTYLHQGLED ELEEDDDRVP TPPVRGVASS 
PAISFGQQST ATLTPSPREE MQPMLQAHLD ELTRAYQFDI AKQTWHIQSN NQPPQPPVPP 
LGYVSGALIS DLETDVADDD ADDEEEALEI PRPLRALDQT PGSSMDNLDS SVTGKAFTSS 
QRPRPTSPFS TDSNTSAALS QSQRPRPTKK HKGGRMDQQP ALPHRREGMT DEEALVPYSK 
PSFPSPGGHS SSGTASSKGS TGPRKTEVLR AGHQRNASDL LDIGYMGSNS QGQFTGEL

Genular Protein ID: 1556530623

Symbol: F8W703_HUMAN

Name: N/A

UniProtKB Accession Codes:

F8W703

Database IDs:

ARBA 3 Antibodypedia 1 Bgee 1 CDD 4 CTD 1 ChiTaRS 1 DisGeNET 1 EMBL 9 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 9 MassIVE 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 4 PeptideAtlas 2 Pfam 3 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 3 SMART 4 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 1443
  • Mass: 157778
  • Checksum: 0ACB7BB7E42D4234
  • Sequence:
    • MSLLMFTQLL LCGFLYVRVD GSRLRQEDFP PRIVEHPSDV IVSKGEPTTL NCKAEGRPTP 
TIEWYKDGER VETDKDDPRS HRMLLPSGSL FFLRIVHGRR SKPDEGSYVC VARNYLGEAV 
SRNASLEVAL LRDDFRQNPT DVVVAAGEPA ILECQPPRGH PEPTIYWKKD KVRIDDKEER 
ISIRGGKLMI SNTRKSDAGM YTCVGTNMVG ERDSDPAELT VFERPTFLRR PINQVVLEEE 
AVEFRCQVQG DPQPTVRWKK DDADLPRGRY DIKDDYTLRI KKTMSTDEGT YMCIAENRVG 
KMEASATLTV RARPVAPPQF VVRPRDQIVA QGRTVTFPCE TKGNPQPAVF WQKEGSQNLL 
FPNQPQQPNS RCSVSPTGDL TITNIQRSDA GYYICQALTV AGSILAKAQL EVTDVLTDRP 
PPIILQGPAN QTLAVDGTAL LKCKATGDPL PVISWLKEGF TFPGRDPRAT IQEQGTLQIK 
NLRISDTGTY TCVATSSSGE TSWSAVLDVT ESGATISKNY DLSDLPGPPS KPQVTDVTKN 
SVTLSWQPGT PGTLPASAYI IEAFSQSVSN SWQTVANHVK TTLYTVRGLR PNTIYLFMVR 
AINPQGLSDP SPMSDPVRTQ DISPPAQGVD HRQVQKELGD VLVRLHNPVV LTPTTVQVTW 
TVDRQPQFIQ GYRVMYRQTS GLQATSSWQN LDAKVPTERS AVLVNLKKGV TYEIKVRPYF 
NEFQGMDSES KTVRTTEEAP SAPPQSVTVL TVGSYNSTSI SVSWDPPPPD HQNGIIQEYK 
IWCLGNETRF HINKTVDAAI RSVIIGGLFP GIQYRVEVAA STSAGVGVKS EPQPIIIGRR 
NEVVITENNN SITEQITDVV KQPAFIAGIG GACWVILMGF SIWLYWRRKK RKGLSNYAVT 
FQRGDGGLMS NGSRPGLLNA GDPSYPWLAD SWPATSLPVN NSNSGPNEIG NFGRGDVLPP 
VPGQGDKTAT MLSDGAIYSS IDFTTKTSYN SSSQITQATP YATTQILHSN SIHELAVDLP 
DPQWKSSIQQ KTDLMGFGYS LPDQNKGNNG GKGGKKKKNK NSSKPQKNNG STWANVPLPP 
PPVQPLPGTE LEHYAVEQQE NGYDSDSWCP PLPVQTYLHQ GLEDELEEDD DRVPTPPVRG 
VASSPAISFG QQSTATLTPS PREEMQPMLQ AHLDELTRAY QFDIAKQTWH IQSNNQPPQP 
PVPPLGYVSG ALISDLETDV ADDDADDEEE ALEIPRPLRA LDQTPGSSMD NLDSSVTGSM 
VNGWGSASDE DRNFSSHRSS VGSSSDGSIF ASGSFAQALV AAADKAGFRL DGTSLTRTGK 
AFTSSQRPRP TSPFSTDSNT SAALSQSQRP RPTKKHKGGR MDQQPALPHR REGMTDEEAL 
VPYSKPSFPS PGGHSSSGTA SSKGSTGPRK TEVLRAGHQR NASDLLDIGY MGSNSQGQFT 
GEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.