Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 105.6284
Cell Significance Index: -16.4300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 58.1131
Cell Significance Index: -14.7400 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 33.5294
Cell Significance Index: -15.8300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 30.3502
Cell Significance Index: -12.3300 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 29.6859
Cell Significance Index: -15.2700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 13.3338
Cell Significance Index: -16.4400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 5.7711
Cell Significance Index: -15.4600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.1713
Cell Significance Index: -16.4600 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 3.3890
Cell Significance Index: 82.6900 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 2.9358
Cell Significance Index: 47.3700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 1.8734
Cell Significance Index: -4.1000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.1493
Cell Significance Index: 15.6800 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 1.0786
Cell Significance Index: 9.0600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.8175
Cell Significance Index: 17.9000 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.8006
Cell Significance Index: 9.9300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.7544
Cell Significance Index: 151.3400 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 0.6724
Cell Significance Index: 7.0200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6561
Cell Significance Index: 592.3700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.6329
Cell Significance Index: 33.2300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.5195
Cell Significance Index: 14.1400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.4560
Cell Significance Index: 23.6900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.4454
Cell Significance Index: 51.9100 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.3739
Cell Significance Index: 4.0700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3711
Cell Significance Index: 60.3500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.3675
Cell Significance Index: 22.5900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.3286
Cell Significance Index: 117.8700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.3092
Cell Significance Index: 19.4900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.3048
Cell Significance Index: 22.7200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2970
Cell Significance Index: 32.3100 - Cell Name: suprabasal keratinocyte (CL4033013)
Fold Change: 0.2500
Cell Significance Index: 4.0200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.2428
Cell Significance Index: 6.2400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.2123
Cell Significance Index: 146.8000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1911
Cell Significance Index: 8.9100 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.1899
Cell Significance Index: 1.1800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1668
Cell Significance Index: 31.7500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1559
Cell Significance Index: 15.4200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1559
Cell Significance Index: 10.7800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.1414
Cell Significance Index: 3.3900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1246
Cell Significance Index: 22.4700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1236
Cell Significance Index: 15.8400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.1006
Cell Significance Index: 4.4500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.0906
Cell Significance Index: 5.4400 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0805
Cell Significance Index: 10.4000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.0750
Cell Significance Index: 2.1400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0658
Cell Significance Index: 8.0900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.0629
Cell Significance Index: 2.3800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0530
Cell Significance Index: 23.4300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0525
Cell Significance Index: 28.6800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0258
Cell Significance Index: 0.6900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0250
Cell Significance Index: 3.4400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0226
Cell Significance Index: 1.0600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0181
Cell Significance Index: 0.3100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0031
Cell Significance Index: 0.6200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0021
Cell Significance Index: 0.0600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0004
Cell Significance Index: -0.0300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0037
Cell Significance Index: -0.1300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0062
Cell Significance Index: -0.7300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0065
Cell Significance Index: -0.1400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0068
Cell Significance Index: -12.7900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0088
Cell Significance Index: -16.2000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0098
Cell Significance Index: -15.1200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0098
Cell Significance Index: -0.6900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0144
Cell Significance Index: -19.5500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0164
Cell Significance Index: -12.0300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0171
Cell Significance Index: -12.9400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0182
Cell Significance Index: -13.5100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0191
Cell Significance Index: -12.1300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0248
Cell Significance Index: -11.2500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0282
Cell Significance Index: -15.8900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0283
Cell Significance Index: -0.7900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0305
Cell Significance Index: -19.0400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0315
Cell Significance Index: -1.4300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0446
Cell Significance Index: -12.8400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0586
Cell Significance Index: -6.7200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0706
Cell Significance Index: -5.4200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0783
Cell Significance Index: -8.0000 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.0809
Cell Significance Index: -0.6600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0837
Cell Significance Index: -12.1700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0898
Cell Significance Index: -18.9100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0902
Cell Significance Index: -1.5100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0905
Cell Significance Index: -15.4600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1135
Cell Significance Index: -6.3700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1528
Cell Significance Index: -7.9600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1561
Cell Significance Index: -16.2500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1603
Cell Significance Index: -9.8300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1649
Cell Significance Index: -10.6400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1728
Cell Significance Index: -3.6800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1785
Cell Significance Index: -14.1400 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.1900
Cell Significance Index: -2.2700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1951
Cell Significance Index: -4.1400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1969
Cell Significance Index: -6.2700 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2049
Cell Significance Index: -2.9400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2190
Cell Significance Index: -7.1700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2198
Cell Significance Index: -7.0400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.2553
Cell Significance Index: -2.9000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.2632
Cell Significance Index: -7.0400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.2804
Cell Significance Index: -7.0100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.2883
Cell Significance Index: -5.7000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2925
Cell Significance Index: -10.2500 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.3015
Cell Significance Index: -3.7600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3263583975
Symbol: RTN2_HUMAN
Name: Reticulon-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9693037
Title: cDNA cloning, genomic organization, and expression of the human RTN2 gene, a member of a gene family encoding reticulons.
PubMed ID: 9693037
PubMed ID: 9530622
Title: Molecular cloning of a novel mouse gene with predominant muscle and neural expression.
PubMed ID: 9530622
PubMed ID: 12832288
Title: A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family.
PubMed ID: 12832288
PubMed ID: 15286784
Title: Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation.
PubMed ID: 15286784
DOI: 10.1038/nm1088
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22232211
Title: Mutations in the ER-shaping protein reticulon 2 cause the axon-degenerative disorder hereditary spastic paraplegia type 12.
PubMed ID: 22232211
DOI: 10.1172/jci60560
PubMed ID: 25612671
Title: Identification and characterization of TMEM33 as a reticulon-binding protein.
PubMed ID: 25612671
Sequence Information:
- Length: 545
- Mass: 59264
- Checksum: 971FD2F909E1E9E6
- Sequence:
MGQVLPVFAH CKEAPSTASS TPDSTEGGND DSDFRELHTA REFSEEDEEE TTSQDWGTPR ELTFSYIAFD GVVGSGGRRD STARRPRPQG RSVSEPRDQH PQPSLGDSLE SIPSLSQSPE PGRRGDPDTA PPSERPLEDL RLRLDHLGWV ARGTGSGEDS STSSSTPLED EEPQEPNRLE TGEAGEELDL RLRLAQPSSP EVLTPQLSPG SGTPQAGTPS PSRSRDSNSG PEEPLLEEEE KQWGPLEREP VRGQCLDSTD QLEFTVEPRL LGTAMEWLKT SLLLAVYKTV PILELSPPLW TAIGWVQRGP TPPTPVLRVL LKWAKSPRSS GVPSLSLGAD MGSKVADLLY WKDTRTSGVV FTGLMVSLLC LLHFSIVSVA AHLALLLLCG TISLRVYRKV LQAVHRGDGA NPFQAYLDVD LTLTREQTER LSHQITSRVV SAATQLRHFF LVEDLVDSLK LALLFYILTF VGAIFNGLTL LILGVIGLFT IPLLYRQHQA QIDQYVGLVT NQLSHIKAKI RAKIPGTGAL ASAAAAVSGS KAKAE
Genular Protein ID: 4265172808
Symbol: A8K7F2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 472
- Mass: 51296
- Checksum: 4CD598862AD643D4
- Sequence:
MGQVLPVFAH CKEAPSTASS TPDSTEGGND DSDFRELHTA REFSEEDEEE TTSQDWGTPR ELTFSYIAFD GVVGSGGRRD STARRPRPQG RSVSEPRDQH PQPSLGDSLE SIPSLSQSPE PGRRGDPDTA PPSERPLEDL RLRLDHLGWV ARGTGSGEDS STSSSTPLED EEPQEPNRLE TGEAGEELDL RLRLAQPSSP EVLTPQLSPG SGTPQAGTPS PSRSRDSNSG PEEPLLEEEE KQWGPLEREP VRGQCLDSTD QLEFTVEPRL LVADLLYWKD TRTSGVVFTG LMVSLLCLLH FSIVSVAAHL ALLLLCGTIS LRVCRKVLQA VHRGDGANPF QAYLDVDLTL TREQTGRLSH QITSRVVSAA TQLRHFFLVE DLVDSLKLAL LFYILTFVGA IFNGLTLLIL GVIGLFTIPL LYRQHQAQID QYVGLVTNQL SHIKAKIRAK IPGTGALASA AAAVSGSKAK AE
Genular Protein ID: 546638114
Symbol: Q6GMT0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 545
- Mass: 59324
- Checksum: 971FD2F909F1E8E6
- Sequence:
MGQVLPVFAH CKEAPSTASS TPDSTEGGND DSDFRELHTA REFSEEDEEE TTSQDWGTPR ELTFSYIAFD GVVGSGGRRD STARRPRPQG RSVSEPRDQH PQPSLGDSLE SIPSLSQSPE PGRRGDPDTA PPSERPLEDL RLRLDHLGWV ARGTGSGEDS STSSSTPLED EEPQEPNRLE TGEAGEELDL RLRLAQPSSP EVLTPQLSPG SGTPQAGTPS PSRSRDSNSG PEEPLLEEEE KQWGPLEREP VRGQCLDSTD QLEFTVEPRL LGTAMEWLKT SLLLAVYKTV PILELSPPLW TAIGWVQRGP TPPTPVLRVL LKWAKSPRSS GVPSLSLGAD MGSKVADLLY WKDTRTSGVV FTGLMVSLLC LLHFSIVSVA AHLALLLLCG TISLRVYRKV LQAVHRGDGA NPFQAYLDVD LTLTREQTER LSHQITSRVV SAATQLRHFF LVEDLVDSLK LALLFYILTF VGAIFNGLTL LILGVIGLFT IPLLYRQHQA QIDQYVGLVT NQLSHIKAKI RAKIPGTGAL AFAAAAVSGS KAKAE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.