Details for: SAA1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: salivary gland glandular cell (CL1001596)
Fold Change: 17.7414
Cell Significance Index: 98.7500 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 11.4005
Cell Significance Index: 168.2700 - Cell Name: colonocyte (CL1000347)
Fold Change: 9.1523
Cell Significance Index: 56.5600 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: 5.9540
Cell Significance Index: 124.1800 - Cell Name: endothelial tip cell (CL0000704)
Fold Change: 5.8439
Cell Significance Index: 25.1300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 5.4340
Cell Significance Index: 253.3600 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 5.4319
Cell Significance Index: 68.4000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 4.5183
Cell Significance Index: 319.5500 - Cell Name: lactocyte (CL0002325)
Fold Change: 3.4315
Cell Significance Index: 443.3200 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 3.2921
Cell Significance Index: 55.4600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.5629
Cell Significance Index: 69.7600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 2.4661
Cell Significance Index: 78.9900 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 2.2483
Cell Significance Index: 19.3200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 1.8764
Cell Significance Index: 46.9100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 1.7161
Cell Significance Index: 80.6600 - Cell Name: liver dendritic cell (CL2000055)
Fold Change: 1.6604
Cell Significance Index: 4.3800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 1.5675
Cell Significance Index: 96.1100 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.5202
Cell Significance Index: 29.6700 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 1.4881
Cell Significance Index: 15.3500 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: 1.1576
Cell Significance Index: 4.3600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.0232
Cell Significance Index: 452.3700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.8853
Cell Significance Index: 483.4600 - Cell Name: epithelial cell of lacrimal sac (CL1000436)
Fold Change: 0.8727
Cell Significance Index: 6.2800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.7536
Cell Significance Index: 21.0600 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: 0.7077
Cell Significance Index: 5.8500 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.6611
Cell Significance Index: 9.0200 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 0.6557
Cell Significance Index: 4.0400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.5149
Cell Significance Index: 26.7500 - Cell Name: basal-myoepithelial cell of mammary gland (CL0002324)
Fold Change: 0.4552
Cell Significance Index: 3.3700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4365
Cell Significance Index: 83.0600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4347
Cell Significance Index: 19.7100 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.3855
Cell Significance Index: 2.2200 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.3472
Cell Significance Index: 3.4300 - Cell Name: epidermal cell (CL0000362)
Fold Change: 0.3282
Cell Significance Index: 0.7400 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.2408
Cell Significance Index: 2.3300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.2363
Cell Significance Index: 17.6100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.2220
Cell Significance Index: 168.0500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2023
Cell Significance Index: 182.6300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.1880
Cell Significance Index: 5.3900 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 0.1553
Cell Significance Index: 6.7500 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.1517
Cell Significance Index: 1.2600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1418
Cell Significance Index: 14.0300 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.1187
Cell Significance Index: 1.5000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.0995
Cell Significance Index: 16.1800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0587
Cell Significance Index: 36.6500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0544
Cell Significance Index: 5.9200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0462
Cell Significance Index: 9.1700 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: 0.0391
Cell Significance Index: 0.1700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0025
Cell Significance Index: 0.1800 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0010
Cell Significance Index: 0.1300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0045
Cell Significance Index: -0.7600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0049
Cell Significance Index: -3.6300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0072
Cell Significance Index: -13.5300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0073
Cell Significance Index: -13.5200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0090
Cell Significance Index: -13.8800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0103
Cell Significance Index: -13.9600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0104
Cell Significance Index: -5.8400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0122
Cell Significance Index: -2.5800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0205
Cell Significance Index: -0.7200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0211
Cell Significance Index: -15.4500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0240
Cell Significance Index: -4.3300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0251
Cell Significance Index: -15.9700 - Cell Name: salivary gland cell (CL0009005)
Fold Change: -0.0314
Cell Significance Index: -0.3900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0323
Cell Significance Index: -0.9300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0329
Cell Significance Index: -14.9200 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: -0.0368
Cell Significance Index: -0.3500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0377
Cell Significance Index: -13.5200 - Cell Name: hepatocyte (CL0000182)
Fold Change: -0.0389
Cell Significance Index: -0.5400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.0393
Cell Significance Index: -2.3600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0528
Cell Significance Index: -6.0500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0535
Cell Significance Index: -15.3900 - Cell Name: erythroblast (CL0000765)
Fold Change: -0.0537
Cell Significance Index: -0.6400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0676
Cell Significance Index: -13.5700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0696
Cell Significance Index: -7.1100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0793
Cell Significance Index: -9.7500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0799
Cell Significance Index: -10.9700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0854
Cell Significance Index: -1.8500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0910
Cell Significance Index: -10.3900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0997
Cell Significance Index: -11.6200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1039
Cell Significance Index: -15.1100 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: -0.1157
Cell Significance Index: -1.6000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1407
Cell Significance Index: -14.6500 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: -0.1669
Cell Significance Index: -1.0300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1805
Cell Significance Index: -13.8500 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.1828
Cell Significance Index: -3.2300 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -0.1934
Cell Significance Index: -2.4900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1996
Cell Significance Index: -12.5800 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.2085
Cell Significance Index: -6.1400 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.2217
Cell Significance Index: -3.4300 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.2324
Cell Significance Index: -8.5300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.2463
Cell Significance Index: -5.1100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2584
Cell Significance Index: -13.4600 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: -0.2874
Cell Significance Index: -2.6400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3000
Cell Significance Index: -16.8400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.3071
Cell Significance Index: -8.2000 - Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
Fold Change: -0.3143
Cell Significance Index: -3.1500 - Cell Name: inflammatory macrophage (CL0000863)
Fold Change: -0.3345
Cell Significance Index: -2.5700 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.3398
Cell Significance Index: -5.1200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3427
Cell Significance Index: -8.8100 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: -0.3521
Cell Significance Index: -1.2300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2658060118
Symbol: SAA1_HUMAN
Name: Serum amyloid A-1 protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3839415
Title: Human serum amyloid A (SAA): biosynthesis and postsynthetic processing of preSAA and structural variants defined by complementary DNA.
PubMed ID: 3839415
DOI: 10.1021/bi00333a018
PubMed ID: 3183061
Title: Human serum amyloid A. Three hepatic mRNAs and the corresponding proteins in one person.
PubMed ID: 3183061
DOI: 10.1172/jci113779
PubMed ID: 1656519
Title: The human acute-phase serum amyloid A gene family: structure, evolution and expression in hepatoma cells.
PubMed ID: 1656519
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1971508
Title: Heterogeneity of human serum amyloid A protein. Five different variants from one individual demonstrated by cDNA sequence analysis.
PubMed ID: 1971508
DOI: 10.1042/bj2680187
PubMed ID: 7115671
Title: Amino acid sequence of amyloid-related apoprotein (apoSAA1) from human high-density lipoprotein.
PubMed ID: 7115671
DOI: 10.1021/bi00257a008
PubMed ID: 1546977
Title: Human serum amyloid A protein. Complete amino acid sequence of a new variant.
PubMed ID: 1546977
DOI: 10.1042/bj2820615
PubMed ID: 6155694
Title: An unusually large (83 amino acid residues) amyloid fibril protein AA from a patient with Waldenstrom's macroglobulinaemia and amyloidosis.
PubMed ID: 6155694
PubMed ID: 5055786
Title: Amino acid sequence of an amyloid fibril protein of unknown origin.
PubMed ID: 5055786
PubMed ID: 5056669
Title: The amino acid sequence of a major nonimmunoglobulin component of some amyloid fibrils.
PubMed ID: 5056669
DOI: 10.1172/jci107098
PubMed ID: 4816450
Title: The complete amino-acid sequence of non-immunoglobulin amyloid fibril protein AS in rheumatoid arthritis.
PubMed ID: 4816450
PubMed ID: 1463770
Title: Identification of two novel amyloid A protein subsets coexisting in an individual patient of AA-amyloidosis.
PubMed ID: 1463770
PubMed ID: 1259755
Title: The complete amino acid sequence of an amyloid fibril protein AA1 of unusual size (64 residues).
PubMed ID: 1259755
PubMed ID: 11946204
Title: The major proteins of human and monkey amyloid substance: common properties including unusual N-terminal amino acid sequences.
PubMed ID: 11946204
PubMed ID: 3442653
Title: Degradation and deposition of amyloid AA fibrils are tissue specific.
PubMed ID: 3442653
DOI: 10.1021/bi00399a035
PubMed ID: 12973732
Title: Identification and validation of a potential lung cancer serum biomarker detected by matrix-assisted laser desorption/ionization-time of flight spectra analysis.
PubMed ID: 12973732
PubMed ID: 8783012
Title: Characterization of human serum amyloid A protein isoforms separated by two-dimensional electrophoresis by liquid chromatography/electrospray ionization tandem mass spectrometry.
PubMed ID: 8783012
PubMed ID: 8670280
Title: A protein AA-variant derived from a novel serum AA protein, SAA1 delta, in an individual from Papua New Guinea.
PubMed ID: 8670280
PubMed ID: 10211414
Title: Revised nomenclature for serum amyloid A (SAA). Nomenclature Committee of the International Society of Amyloidosis. Part 2.
PubMed ID: 10211414
PubMed ID: 12606051
Title: Detection of novel truncated forms of human serum amyloid A protein in human plasma.
PubMed ID: 12606051
PubMed ID: 8512321
Title: A novel polymorphism of human serum amyloid A protein, SAA1 gamma, is characterized by alanines at both residues 52 and 57.
PubMed ID: 8512321
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24706838
Title: Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
PubMed ID: 24706838
Sequence Information:
- Length: 122
- Mass: 13546
- Checksum: 8C43BF06AA47B179
- Sequence:
MKLLTGLVFC SLVLGVSSRS FFSFLGEAFD GARDMWRAYS DMREANYIGS DKYFHARGNY DAAKRGPGGA WAAEVITDAR ENIQRFFGHG AEDSLADQAA NEWGRSGKDP NHFRPAGLPE KY
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.