Details for: SMTN

Gene ID: 6525

Symbol: SMTN

Ensembl ID: ENSG00000183963

Description: smoothelin

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 124.7869
    Cell Significance Index: -19.4100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 78.6143
    Cell Significance Index: -19.9400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 42.5839
    Cell Significance Index: -17.3000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 38.5281
    Cell Significance Index: -18.1900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 18.0991
    Cell Significance Index: -17.2800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 16.1725
    Cell Significance Index: -19.9400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.4360
    Cell Significance Index: -19.9200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.5287
    Cell Significance Index: -12.1000
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 5.2765
    Cell Significance Index: 27.7700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.0633
    Cell Significance Index: -19.9800
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: 1.4825
    Cell Significance Index: 6.8500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2133
    Cell Significance Index: 131.9800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1960
    Cell Significance Index: 194.5300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.9286
    Cell Significance Index: 26.6200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.8771
    Cell Significance Index: 15.5000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.8598
    Cell Significance Index: 51.6200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.8047
    Cell Significance Index: 23.1900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6568
    Cell Significance Index: 45.4200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.6240
    Cell Significance Index: 32.5100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5869
    Cell Significance Index: 45.0400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.5705
    Cell Significance Index: 42.5200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.5320
    Cell Significance Index: 68.7300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.4357
    Cell Significance Index: 197.7600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4300
    Cell Significance Index: 19.4900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3702
    Cell Significance Index: 50.8400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3303
    Cell Significance Index: 32.6700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.2990
    Cell Significance Index: 4.3000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2891
    Cell Significance Index: 37.0700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2755
    Cell Significance Index: 12.9500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2308
    Cell Significance Index: 8.1100
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.2261
    Cell Significance Index: 1.7900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2238
    Cell Significance Index: 44.4100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2086
    Cell Significance Index: 5.8300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1724
    Cell Significance Index: 3.7400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1603
    Cell Significance Index: 30.5000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1540
    Cell Significance Index: 3.2800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.1068
    Cell Significance Index: 11.1200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.1059
    Cell Significance Index: 0.6400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0941
    Cell Significance Index: 1.9700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0853
    Cell Significance Index: 1.2600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0792
    Cell Significance Index: 4.9900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0785
    Cell Significance Index: 4.0800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0783
    Cell Significance Index: 34.6300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0689
    Cell Significance Index: 1.4300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0555
    Cell Significance Index: 9.4900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0541
    Cell Significance Index: 0.9100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0415
    Cell Significance Index: 78.1000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0359
    Cell Significance Index: 19.6300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0349
    Cell Significance Index: 6.2900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0195
    Cell Significance Index: 2.3000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0072
    Cell Significance Index: 0.8900
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0016
    Cell Significance Index: -0.0400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0067
    Cell Significance Index: -4.2300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0087
    Cell Significance Index: -15.9800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0106
    Cell Significance Index: -16.3400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0137
    Cell Significance Index: -9.4800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0144
    Cell Significance Index: -5.1800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0144
    Cell Significance Index: -19.5700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0166
    Cell Significance Index: -12.1600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0176
    Cell Significance Index: -0.2100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0232
    Cell Significance Index: -17.5900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0259
    Cell Significance Index: -19.1800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0330
    Cell Significance Index: -20.5800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0342
    Cell Significance Index: -19.2700
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: -0.0347
    Cell Significance Index: -0.3300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0579
    Cell Significance Index: -2.7000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0590
    Cell Significance Index: -11.8300
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.0607
    Cell Significance Index: -0.5100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0632
    Cell Significance Index: -18.1900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0722
    Cell Significance Index: -10.4900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0744
    Cell Significance Index: -7.6000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0766
    Cell Significance Index: -8.9300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0810
    Cell Significance Index: -5.7300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0970
    Cell Significance Index: -20.4300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1014
    Cell Significance Index: -2.2200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1036
    Cell Significance Index: -2.5900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1095
    Cell Significance Index: -12.5500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1286
    Cell Significance Index: -4.1200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1434
    Cell Significance Index: -3.8300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1721
    Cell Significance Index: -8.7000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2136
    Cell Significance Index: -5.4900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2154
    Cell Significance Index: -2.2300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2200
    Cell Significance Index: -17.4300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2579
    Cell Significance Index: -13.5400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2590
    Cell Significance Index: -16.7100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2645
    Cell Significance Index: -16.2600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2659
    Cell Significance Index: -17.8800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2712
    Cell Significance Index: -16.6300
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.2747
    Cell Significance Index: -4.2500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2778
    Cell Significance Index: -15.5900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2924
    Cell Significance Index: -7.9600
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.3120
    Cell Significance Index: -1.9200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3206
    Cell Significance Index: -11.1400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3300
    Cell Significance Index: -6.4400
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.3477
    Cell Significance Index: -5.2400
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.3840
    Cell Significance Index: -5.3700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3874
    Cell Significance Index: -5.2900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4157
    Cell Significance Index: -10.9300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4176
    Cell Significance Index: -12.3000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.4195
    Cell Significance Index: -4.5600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key characteristics** The smoothelin protein is a cytoskeletal protein that belongs to the intermediate filament family. It is composed of two alpha-helical coiled-coil domains that are linked by a short linker region. The smoothelin protein plays a critical role in maintaining the structural integrity of smooth muscle cells, particularly in the context of muscle contraction and relaxation. It interacts with actin filaments, which are essential components of the cytoskeleton, and modulates their dynamics to regulate muscle contraction. Additionally, smoothelin has been shown to interact with other proteins, such as myosin and tropomyosin, to regulate muscle contraction and relaxation. **Pathways and functions** The smoothelin protein is involved in various cellular processes, including: 1. **Muscle contraction and relaxation**: Smoothelin plays a critical role in regulating muscle contraction and relaxation by modulating the dynamics of actin filaments. 2. **Cytoskeleton organization**: Smoothelin interacts with actin filaments and other cytoskeletal proteins to maintain the structural integrity of smooth muscle cells. 3. **Muscle organ development**: Smoothelin is expressed in developing muscle tissues, suggesting its role in muscle organogenesis. 4. **Smooth muscle contraction**: Smoothelin regulates smooth muscle contraction by modulating the interaction between actin filaments and myosin. **Clinical significance** Dysregulation of the SMTN gene has been implicated in various diseases, including: 1. **Muscle disorders**: Mutations in the SMTN gene have been associated with muscle disorders, such as smooth muscle cell hypertrophy and fibrosis. 2. **Cardiovascular disease**: Smoothelin has been shown to play a role in regulating smooth muscle cell contraction and relaxation, which is essential for maintaining cardiovascular homeostasis. Dysregulation of the SMTN gene may contribute to cardiovascular disease. 3. **Neurological disorders**: Smoothelin has been expressed in the central nervous system, and its dysregulation may contribute to neurological disorders, such as neuropathic pain and muscle spasms. In conclusion, the SMTN gene and its product, smoothelin, play a critical role in maintaining the structural integrity and function of smooth muscle cells. Dysregulation of the SMTN gene has been implicated in various diseases, highlighting the importance of this gene in human health and disease. Further research is needed to fully elucidate the mechanisms by which smoothelin regulates muscle contraction and relaxation, as well as its role in various diseases.

Genular Protein ID: 959975037

Symbol: SMTN_HUMAN

Name: Smoothelin

UniProtKB Accession Codes:

P53814 O00569 O95769 O95937 Q8N4H8 Q8WWW1 Q8WWW2 Q9P1S8 Q9UIT1 Q9UIT2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 39 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 5 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8707825

Title: Smoothelin, a novel cytoskeletal protein specific for smooth muscle cells.

PubMed ID: 8707825

DOI: 10.1083/jcb.134.2.401

PubMed ID: 10023782

Title: A novel isoform of the smooth muscle cell differentiation marker smoothelin.

PubMed ID: 10023782

DOI: 10.1007/s001090050352

PubMed ID: 11316948

Title: Identification and characterization of novel smoothelin isoforms in vascular smooth muscle.

PubMed ID: 11316948

DOI: 10.1159/000051039

PubMed ID: 12176134

Title: Expression of the smoothelin gene is mediated by alternative promoters.

PubMed ID: 12176134

DOI: 10.1016/s0008-6363(02)00491-1

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 917
  • Mass: 99059
  • Checksum: EC508A8239AA6B36
  • Sequence:
    • MADEALAGLD EGALRKLLEV TADLAERRRI RSAIRELQRQ ELEREEEALA SKRFRAERQD 
NKENWLHSQQ REAEQRAALA RLAGQLESMN DVEELTALLR SAGEYEERKL IRAAIRRVRA 
QEIEAATLAG RLYSGRPNSG SREDSKGLAA HRLEQCEVPE REEQEQQAEV SKPTPTPEGT 
SQDVTTVTLL LRAPPGSTSS SPASPSSSPT PASPEPPLEP AEAQCLTAEV PGSPEPPPSP 
PKTTSPEPQE SPTLPSTEGQ VVNKLLSGPK ETPAAQSPTR GPSDTKRADV AGPRPCQRSL 
SVLSPRQPAQ NRESTPLASG PSSFQRAGSV RDRVHKFTSD SPMAARLQDG TPQAALSPLT 
PARLLGPSLT STTPASSSSG SSSRGPSDTS SRFSKEQRGV AQPLAQLRSC PQEEGPRGRG 
LAARPLENRA GGPVARSEEP GAPLPVAVGT AEPGGSMKTT FTIEIKDGRG QASTGRVLLP 
TGNQRAELTL GLRAPPTLLS TSSGGKSTIT RVNSPGTLAR LGSVTHVTSF SHAPPSSRGG 
CSIKMEAEPA EPLAAAVEAA NGAEQTRVNK APEGRSPLSA EELMTIEDEG VLDKMLDQST 
DFEERKLIRA ALRELRQRKR DQRDKERERR LQEARGRPGE GRGNTATETT TRHSQRAADG 
SAVSTVTKTE RLVHSNDGTR TARTTTVESS FVRRSENGSG STMMQTKTFS SSSSSKKMGS 
IFDREDQASP RAGSLAALEK RQAEKKKELM KAQSLPKTSA SQARKAMIEK LEKEGAAGSP 
GGPRAAVQRS TSFGVPNANS IKQMLLDWCR AKTRGYEHVD IQNFSSSWSD GMAFCALVHN 
FFPEAFDYGQ LSPQNRRQNF EVAFSSAEML VDCVPLVEVD DMMIMGKKPD PKCVFTYVQS 
LYNHLRRHEL RLRGKNV

Genular Protein ID: 3394760650

Symbol: A0A087WVP4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WVP4

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18477386

Title: Finishing the finished human chromosome 22 sequence.

PubMed ID: 18477386

DOI: 10.1186/gb-2008-9-5-r78

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 971
  • Mass: 104846
  • Checksum: 81ED06689FC916DC
  • Sequence:
    • MGGMGTPGDL HAACPSTTRR DALCLGPEFE FDLRHSAGCP GDLGFFPLDP DTEAGGSGCL 
PTWLPLRRLA RGRLEVTADL AERRRIRSAI RELQRQELER EEEALASKRF RAERQDNKEN 
WLHSQQREAE QRAALARLAG QLESMNDVEE LTALLRSAGE YEERKLIRAA IRRVRAQEIE 
AATLAGRLYS GRPNSGSRED SKGLAAHRLE QCEVPEREEQ EQQAEVSKPT PTPEGTSQDV 
TTVTLLLRAP PGSTSSSPAS PSSSPTPASP EPPLEPAEAQ CLTAEVPGSP EPPPSPPKTT 
SPEPQESPTL PSTEGQVVNK LLSGPKETPA AQSPTRGPSD TKRADVAGPR PCQRSLSVLS 
PRQPAQNRES TPLASGPSSF QRAGSVRDRV HKFTSDSPMA ARLQDGTPQA ALSPLTPARL 
LGPSLTSTTP ASSSSGSSSR GPSDTSSRFS KEQRGVAQPL AQLRSCPQEE GPRGRGLAAR 
PLENRAGGPV ARSEEPGAPL PVAVGTAEPG GSMKTTFTIE IKDGRGQAST GRVLLPTGNQ 
RAELTLGLRA PPTLLSTSSG GKSTITRVNS PGTLARLGSV THVTSFSHAP PSSRGGCSIK 
MEAEPAEPLA AAVEAANGAE QTRVNKAPEG RSPLSAEELM TIEDEGVLDK MLDQSTDFEE 
RKLIRAALRE LRQRKRDQRD KERERRLQEA RGRPGEGRGN TATETTTRHS QRAADGSAVS 
TVTKTERLVH SNDGTRTART TTVESSFVRR SENGSGSTMM QTKTFSSSSS SKKMGSIFDR 
EDQASPRAGS LAALEKRQAE KKKELMKAQS LPKTSASQAR KAMIEKLEKE GAAGSPGGPR 
AAVQRSTSFG VPNANSIKQM LLDWCRAKTR GYEHVDIQNF SSSWSDGMAF CALVHNFFPE 
AFDYGQLSPQ NRRQNFEVAF SSAETHADCP QLLDTEDMVR LREPDWKCVY TYIQEFYRCL 
VQKGLVKTKK S

Genular Protein ID: 445698046

Symbol: B4DI56_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DI56

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 971
  • Mass: 104900
  • Checksum: 8543D447D9505D48
  • Sequence:
    • MGGMGTPGDL HAACPSTTRR DALCLGPEFE FDLRHSAGCP GDLGFFPLDP DTEAGGSGCL 
PTWLPLRRLA RGRLEVTADL AERRRIRSAI RELQRQELER EEEALASKRF RAERQDNKEN 
WLHSQQREAE QRAALARLAG QLESMNDVEE LTALLRSAGE YEERKLIRAA IRRVRAQEIE 
AATLAGRLYS GRPNSGSRED SKGLAAHRLE QCEVPEREEQ EQQAEVSKPT PTPEGTSQDV 
TTVTLLLRAP PGSTSSSPAS PSSSPTPASP EPPLEPAEAQ CLTAEVPGSP EPPPSPPKTT 
SPEPQESPTL PSTEGQVVNK LLSGPKETPA AQSPTRGPSD TKRADVAGPR PCQRSLSVLS 
PRQPAQNRES TPLASGPSSF QRAGSVRDRV HKFTSDSPMA ARLQDGTPQA ALSPLTPARL 
LGPSLTSTTP ASSSSGSSSR GPSDTSSRFS KEQRGVAQPL AQLRSCPQEE GPRGRGLAAR 
PLENRAGGPV ARSEEPGAPL PVAVGTAEPG GSMKTTFTIE IKDGRGQAST GRVLLPTGNQ 
RAELTLGLRA PPTLLSTSSG GKSTITRVNS PGTLARLGSV THVTSFSHAP PSSRGGCSIK 
MEPEPAEPLA AAVEVANGAE QTRVNKAPEG RSPLSAEELM TIEDEGVLDK MLDQSTDFEE 
RKLIRAALRE LRQRKRDQRD KERERRLQEA RGRPGEGRGN TATETTTRHS QRAADGSAVS 
TVTKTERLVH SNDGTRTART TTVESSFVRR SENGSGSTMM QTKTFSSSSS SKKMGSIFDR 
EDQASPRAGS LAALEKRQAE KKKELMKAQS LPKTSASQAR KAMIEKLEKE GAAGSPGGPR 
AAVQRSTSFG VPNANSIKQM LLDWCRAKTR GYEHVDIQNF SSSWSDGMAF CALVHNFFPE 
AFDYGQLSPQ NRRQNFEVAF SSAETHADCP QLLDTEDMVR LREPDWKCVY TYIQEFYRCL 
VQKGLVKTKK S

Genular Protein ID: 2808287628

Symbol: A0A087X1R1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087X1R1

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 Gene3D 1 GeneTree 1 HGNC 1 IntAct 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 2 SAM 2 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18477386

Title: Finishing the finished human chromosome 22 sequence.

PubMed ID: 18477386

DOI: 10.1186/gb-2008-9-5-r78

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 1002
  • Mass: 108016
  • Checksum: E1F5191BD11770A8
  • Sequence:
    • MRVHPRPHSR LAAKLAGLEP ETPYPGFEFS ELVTGATGTG DLTRKEPTEL GASEMADEAL 
AGLDEGALRK LLEVTADLAE RRRIRSAIRE LQRQELEREE EALASKRFRA ERQDNKENWL 
HSQQREAEQR AALARLAGQL ESMNDVEELT ALLRSAGEYE ERKLIRAAIR RVRAQEIEAA 
TLAGRLYSGR PNSGSREDSK GLAAHRLEQC EVPEREEQEQ QAEVSKPTPT PEGTSQDVTT 
VTLLLRAPPG STSSSPASPS SSPTPASPEP PLEPAEAQCL TAEVPGSPEP PPSPPKTTSP 
EPQESPTLPS TEGQVVNKLL SGPKETPAAQ SPTRGPSDTK RADVAGPRPC QRSLSVLSPR 
QPAQNRESTP LASGPSSFQR AGSVRDRVHK FTSDSPMAAR LQDGTPQAAL SPLTPARLLG 
PSLTSTTPAS SSSGSSSRGP SDTSSRFSKE QRGVAQPLAQ LRSCPQEEGP RGRGLAARPL 
ENRAGGPVAR SEEPGAPLPV AVGTAEPGGS MKTTFTIEIK DGRGQASTGR VLLPTGNQRA 
ELTLGLRAPP TLLSTSSGGK STITRVNSPG TLARLGSVTH VTSFSHAPPS SRGGCSIKAA 
EDAGTPVAHP PAFSTRRRSS TGTTRSTSLM EAEPAEPLAA AVEAANGAEQ TRVNKAPEGR 
SPLSAEELMT IEDEGVLDKM LDQSTDFEER KLIRAALREL RQRKRDQRDK ERERRLQEAR 
GRPGEGRGNT ATETTTRHSQ RAADGSAVST VTKTERLVHS NDGTRTARTT TVESSFVRRS 
ENGSGSTMMQ TKTFSSSSSS KKMGSIFDRE DQASPRAGSL AALEKRQAEK KKELMKAQSL 
PKTSASQARK AMIEKLEKEG AAGSPGGPRA AVQRSTSFGV PNANSIKQML LDWCRAKTRG 
YEHVDIQNFS SSWSDGMAFC ALVHNFFPEA FDYGQLSPQN RRQNFEVAFS SAEMLVDCVP 
LVEVDDMMIM GKKPDPKCVF TYVQSLYNHL RRHELRLRGK NV

Genular Protein ID: 531476108

Symbol: B4E229_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E229

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 IntAct 1 InterPro 4 MINT 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2 SUPFAM 1 iPTMnet 1

Sequence Information:

  • Length: 942
  • Mass: 101061
  • Checksum: 6E30BFEA2C334A76
  • Sequence:
    • MRVHPRPHSR LAAKLAGLEP ETPYPGFEFS ELVTGATGTG DLTRKEPTEL GASEMADEAL 
AGLDEGALRK LLEVTADLAE RRRIRSAIRE LQRQELEREE EALASKRFRA ERQDNKENWL 
HSQQREAEQR AALARLAGQL ESMNDVEELT ALLRSAGEYE ERKLIRAAIR RVRAQEIEAA 
TLAGRLYSGR PNSGSREDSK GLAAHRLEQC EVPEREEQEQ QAEVSKPTPT PEGTSQDVTT 
VTLLLRAPPG STSSSPASPS SSPTPASPEP PLEPAEAQCL TAEVPGSPEP PPSPPKTTSP 
EPQESPTLPS TEGQVVNKLL SGPKETPAAQ SPTRGPSDTK RADVAGPRPC QRSLSVLSPR 
QPAQNRESTP LASGPSSFQR AGSVRDRVHK FTSDSPMAAR LQDGTPQAAL SPLTPARLLG 
PSLTSTTPAS SSSGSSSRGP SDTSSRFSKE QRGVAQPLAQ LRSCPQEEGP RGRGLAARPL 
ENRAGGPVAR SEEPGAPLPV AVGTAEPGGS MKTTFTIEIK DGRGQASTGR VLLPTGNQRA 
ELTLGLRAPP TLLSTSSGGK STITRVNSPG TLARLGSVTH VTSFSHAPPS SRGGCSIKAA 
EDAGTPVAHP PAFSTRRRSS TGTTRSTSLM EPEPAEPLAA AVEAANGAEQ TRVNKAPEGR 
SPLSAEELMT IEDEGVLDKM LDQSTDFEER KLIRAALREL RQRKRDQRDK ERERRLQEAR 
GRPGEGRGNT ATETTTRHSQ RAADGSAVST VTKTERLVHS NDGTRTARTT TVESSFVRRS 
ENGSGSTMMQ TKTFSSSSSS KKMGSIFDRE DQASPRAGSL AALEERQAEK KKELMKAQSL 
PKTSASQARK AMIEKLEKEG AAGSPGGPRA AVQRSTSFGV PNANSIKQML LDWCRAKTRG 
YEHVDIQNFS SSWSDGMAFC ALVHNFFPEA FDYGQLSPQN RR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.