Details for: SNAPC4
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 73.2906
Cell Significance Index: -11.4000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 44.1368
Cell Significance Index: -11.2000 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 28.0861
Cell Significance Index: -11.5700 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 25.7226
Cell Significance Index: -10.4500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 10.7673
Cell Significance Index: -10.2800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 9.5299
Cell Significance Index: -11.7500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 4.5131
Cell Significance Index: -12.0900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 3.0081
Cell Significance Index: -11.8700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.7500
Cell Significance Index: 333.0300 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 1.7210
Cell Significance Index: 28.3600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 1.1286
Cell Significance Index: -2.4700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.8827
Cell Significance Index: 87.3200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.7866
Cell Significance Index: 157.8000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6543
Cell Significance Index: 590.8200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.5401
Cell Significance Index: 58.7500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5367
Cell Significance Index: 32.2200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.5360
Cell Significance Index: 106.3800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4863
Cell Significance Index: 79.1000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.3826
Cell Significance Index: 5.2200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.3731
Cell Significance Index: 14.1300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.3334
Cell Significance Index: 9.6100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.3319
Cell Significance Index: 14.6800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2829
Cell Significance Index: 101.4700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2693
Cell Significance Index: 18.6200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.2558
Cell Significance Index: 7.1500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.2537
Cell Significance Index: 29.5700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1701
Cell Significance Index: 92.8900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1686
Cell Significance Index: 7.6400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1652
Cell Significance Index: 114.2900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.1617
Cell Significance Index: 10.8700 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.1610
Cell Significance Index: 2.2600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1579
Cell Significance Index: 8.2000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.1485
Cell Significance Index: 9.3600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1325
Cell Significance Index: 2.8700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1193
Cell Significance Index: 7.3300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1151
Cell Significance Index: 20.7500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1113
Cell Significance Index: 8.5400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1060
Cell Significance Index: 2.6500 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.1051
Cell Significance Index: 2.8200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.0722
Cell Significance Index: 1.5800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0634
Cell Significance Index: 7.7900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0501
Cell Significance Index: 1.7600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0466
Cell Significance Index: 20.5900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0446
Cell Significance Index: 2.0800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0440
Cell Significance Index: 6.0400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.0339
Cell Significance Index: 4.0000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0262
Cell Significance Index: 1.6900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0207
Cell Significance Index: 1.1600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.0184
Cell Significance Index: 1.1300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0118
Cell Significance Index: 22.2900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0089
Cell Significance Index: 0.4200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0078
Cell Significance Index: 11.9600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0075
Cell Significance Index: 0.1600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0069
Cell Significance Index: 12.7200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0005
Cell Significance Index: 0.6700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0019
Cell Significance Index: -0.3300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0037
Cell Significance Index: -2.3400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0065
Cell Significance Index: -2.9500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0103
Cell Significance Index: -0.2800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0104
Cell Significance Index: -7.5900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0113
Cell Significance Index: -8.3700 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0123
Cell Significance Index: -1.5800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0138
Cell Significance Index: -10.4300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0180
Cell Significance Index: -10.1300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0196
Cell Significance Index: -2.8500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0206
Cell Significance Index: -0.5500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0214
Cell Significance Index: -13.3600 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.0237
Cell Significance Index: -0.3400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0309
Cell Significance Index: -0.7400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0310
Cell Significance Index: -4.0100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0319
Cell Significance Index: -3.6500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0338
Cell Significance Index: -9.7200 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0369
Cell Significance Index: -0.7200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0446
Cell Significance Index: -4.5600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0481
Cell Significance Index: -0.8300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0493
Cell Significance Index: -3.4900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0592
Cell Significance Index: -4.4200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0605
Cell Significance Index: -12.7400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0883
Cell Significance Index: -2.5200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0985
Cell Significance Index: -5.1300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1017
Cell Significance Index: -10.5900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1058
Cell Significance Index: -2.8300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1153
Cell Significance Index: -6.0600 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.1176
Cell Significance Index: -1.2200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1394
Cell Significance Index: -11.0400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1640
Cell Significance Index: -3.4800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1760
Cell Significance Index: -2.9500 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1774
Cell Significance Index: -5.6500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1778
Cell Significance Index: -6.1800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1870
Cell Significance Index: -5.9900 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.1878
Cell Significance Index: -2.7700 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.1995
Cell Significance Index: -3.3600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2011
Cell Significance Index: -6.5900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2074
Cell Significance Index: -2.9700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2140
Cell Significance Index: -5.5000 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2213
Cell Significance Index: -5.8200 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.2328
Cell Significance Index: -5.0300 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.2354
Cell Significance Index: -2.9200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2355
Cell Significance Index: -8.2500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2377
Cell Significance Index: -12.0100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1212419845
Symbol: SNPC4_HUMAN
Name: snRNA-activating protein complex subunit 4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9418884
Title: The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1.
PubMed ID: 9418884
DOI: 10.1128/mcb.18.1.368
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 11056176
Title: A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc.
PubMed ID: 11056176
PubMed ID: 12621023
Title: The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition.
PubMed ID: 12621023
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 36965478
Title: Bi-allelic SNAPC4 variants dysregulate global alternative splicing and lead to neuroregression and progressive spastic paraparesis.
PubMed ID: 36965478
Sequence Information:
- Length: 1469
- Mass: 159433
- Checksum: 78CBCFB1887E106C
- Sequence:
MDVDAEREKI TQEIKELERI LDPGSSGSHV EISESSLESD SEADSLPSED LDPADPPISE EERWGEASND EDDPKDKTLP EDPETCLQLN MVYQEVIQEK LAEANLLLAQ NREQQEELMR DLAGSKGTKV KDGKSLPPST YMGHFMKPYF KDKVTGVGPP ANEDTREKAA QGIKAFEELL VTKWKNWEKA LLRKSVVSDR LQRLLQPKLL KLEYLHQKQS KVSSELERQA LEKQGREAEK EIQDINQLPE EALLGNRLDS HDWEKISNIN FEGSRSAEEI RKFWQNSEHP SINKQEWSRE EEERLQAIAA AHGHLEWQKI AEELGTSRSA FQCLQKFQQH NKALKRKEWT EEEDRMLTQL VQEMRVGSHI PYRRIVYYME GRDSMQLIYR WTKSLDPGLK KGYWAPEEDA KLLQAVAKYG EQDWFKIREE VPGRSDAQCR DRYLRRLHFS LKKGRWNLKE EEQLIELIEK YGVGHWAKIA SELPHRSGSQ CLSKWKIMMG KKQGLRRRRR RARHSVRWSS TSSSGSSSGS SGGSSSSSSS SSEEDEPEQA QAGEGDRALL SPQYMVPDMD LWVPARQSTS QPWRGGAGAW LGGPAASLSP PKGSSASQGG SKEASTTAAA PGEETSPVQV PARAHGPVPR SAQASHSADT RPAGAEKQAL EGGRRLLTVP VETVLRVLRA NTAARSCTQK EQLRQPPLPT SSPGVSSGDS VARSHVQWLR HRATQSGQRR WRHALHRRLL NRRLLLAVTP WVGDVVVPCT QASQRPAVVQ TQADGLREQL QQARLASTPV FTLFTQLFHI DTAGCLEVVR ERKALPPRLP QAGARDPPVH LLQASSSAQS TPGHLFPNVP AQEASKSASH KGSRRLASSR VERTLPQASL LASTGPRPKP KTVSELLQEK RLQEARAREA TRGPVVLPSQ LLVSSSVILQ PPLPHTPHGR PAPGPTVLNV PLSGPGAPAA AKPGTSGSWQ EAGTSAKDKR LSTMQALPLA PVFSEAEGTA PAASQAPALG PGQISVSCPE SGLGQSQAPA ASRKQGLPEA PPFLPAAPSP TPLPVQPLSL THIGGPHVAT SVPLPVTWVL TAQGLLPVPV PAVVSLPRPA GTPGPAGLLA TLLPPLTETR AAQGPRAPAL SSSWQPPANM NREPEPSCRT DTPAPPTHAL SQSPAEADGS VAFVPGEAQV AREIPEPRTS SHADPPEAEP PWSGRLPAFG GVIPATEPRG TPGSPSGTQE PRGPLGLEKL PLRQPGPEKG ALDLEKPPLP QPGPEKGALD LGLLSQEGEA ATQQWLGGQR GVRVPLLGSR LPYQPPALCS LRALSGLLLH KKALEHKATS LVVGGEAERP AGALQASLGL VRGQLQDNPA YLLLRARFLA AFTLPALLAT LAPQGVRTTL SVPSRVGSES EDEDLLSELE LADRDGQPGC TTATCPIQGA PDSGKCSASS CLDTSNDPDD LDVLRTRHAR HTRKRRRLV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.