Details for: SNAPC4

Gene ID: 6621

Symbol: SNAPC4

Ensembl ID: ENSG00000165684

Description: small nuclear RNA activating complex polypeptide 4

Associated with

  • Gene expression (transcription)
    (R-HSA-74160)
  • Rna polymerase iii abortive and retractive initiation
    (R-HSA-749476)
  • Rna polymerase iii transcription
    (R-HSA-74158)
  • Rna polymerase iii transcription initiation
    (R-HSA-76046)
  • Rna polymerase iii transcription initiation from type 3 promoter
    (R-HSA-76071)
  • Rna polymerase ii transcribes snrna genes
    (R-HSA-6807505)
  • Rna polymerase ii transcription
    (R-HSA-73857)
  • Dna binding
    (GO:0003677)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Protein binding
    (GO:0005515)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii general transcription initiation factor activity
    (GO:0016251)
  • Rna polymerase iii general transcription initiation factor activity
    (GO:0000995)
  • Rna polymerase iii type 3 promoter sequence-specific dna binding
    (GO:0001006)
  • Snrna-activating protein complex
    (GO:0019185)
  • Snrna transcription by rna polymerase ii
    (GO:0042795)
  • Snrna transcription by rna polymerase iii
    (GO:0042796)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 73.2906
    Cell Significance Index: -11.4000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 44.1368
    Cell Significance Index: -11.2000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 28.0861
    Cell Significance Index: -11.5700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 25.7226
    Cell Significance Index: -10.4500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 10.7673
    Cell Significance Index: -10.2800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 9.5299
    Cell Significance Index: -11.7500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.5131
    Cell Significance Index: -12.0900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.0081
    Cell Significance Index: -11.8700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.7500
    Cell Significance Index: 333.0300
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 1.7210
    Cell Significance Index: 28.3600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.1286
    Cell Significance Index: -2.4700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.8827
    Cell Significance Index: 87.3200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7866
    Cell Significance Index: 157.8000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6543
    Cell Significance Index: 590.8200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5401
    Cell Significance Index: 58.7500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5367
    Cell Significance Index: 32.2200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5360
    Cell Significance Index: 106.3800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4863
    Cell Significance Index: 79.1000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.3826
    Cell Significance Index: 5.2200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.3731
    Cell Significance Index: 14.1300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3334
    Cell Significance Index: 9.6100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.3319
    Cell Significance Index: 14.6800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2829
    Cell Significance Index: 101.4700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2693
    Cell Significance Index: 18.6200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2558
    Cell Significance Index: 7.1500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.2537
    Cell Significance Index: 29.5700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1701
    Cell Significance Index: 92.8900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1686
    Cell Significance Index: 7.6400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1652
    Cell Significance Index: 114.2900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1617
    Cell Significance Index: 10.8700
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.1610
    Cell Significance Index: 2.2600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1579
    Cell Significance Index: 8.2000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1485
    Cell Significance Index: 9.3600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1325
    Cell Significance Index: 2.8700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1193
    Cell Significance Index: 7.3300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1151
    Cell Significance Index: 20.7500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1113
    Cell Significance Index: 8.5400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1060
    Cell Significance Index: 2.6500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1051
    Cell Significance Index: 2.8200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0722
    Cell Significance Index: 1.5800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0634
    Cell Significance Index: 7.7900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0501
    Cell Significance Index: 1.7600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0466
    Cell Significance Index: 20.5900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0446
    Cell Significance Index: 2.0800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0440
    Cell Significance Index: 6.0400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0339
    Cell Significance Index: 4.0000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0262
    Cell Significance Index: 1.6900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0207
    Cell Significance Index: 1.1600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.0184
    Cell Significance Index: 1.1300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0118
    Cell Significance Index: 22.2900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0089
    Cell Significance Index: 0.4200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0078
    Cell Significance Index: 11.9600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0075
    Cell Significance Index: 0.1600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0069
    Cell Significance Index: 12.7200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0005
    Cell Significance Index: 0.6700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0019
    Cell Significance Index: -0.3300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0037
    Cell Significance Index: -2.3400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0065
    Cell Significance Index: -2.9500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0103
    Cell Significance Index: -0.2800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0104
    Cell Significance Index: -7.5900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0113
    Cell Significance Index: -8.3700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0123
    Cell Significance Index: -1.5800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0138
    Cell Significance Index: -10.4300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0180
    Cell Significance Index: -10.1300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0196
    Cell Significance Index: -2.8500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0206
    Cell Significance Index: -0.5500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0214
    Cell Significance Index: -13.3600
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.0237
    Cell Significance Index: -0.3400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0309
    Cell Significance Index: -0.7400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0310
    Cell Significance Index: -4.0100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0319
    Cell Significance Index: -3.6500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0338
    Cell Significance Index: -9.7200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0369
    Cell Significance Index: -0.7200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0446
    Cell Significance Index: -4.5600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0481
    Cell Significance Index: -0.8300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0493
    Cell Significance Index: -3.4900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0592
    Cell Significance Index: -4.4200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0605
    Cell Significance Index: -12.7400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0883
    Cell Significance Index: -2.5200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0985
    Cell Significance Index: -5.1300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1017
    Cell Significance Index: -10.5900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1058
    Cell Significance Index: -2.8300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1153
    Cell Significance Index: -6.0600
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1176
    Cell Significance Index: -1.2200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1394
    Cell Significance Index: -11.0400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1640
    Cell Significance Index: -3.4800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1760
    Cell Significance Index: -2.9500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1774
    Cell Significance Index: -5.6500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1778
    Cell Significance Index: -6.1800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1870
    Cell Significance Index: -5.9900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.1878
    Cell Significance Index: -2.7700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1995
    Cell Significance Index: -3.3600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2011
    Cell Significance Index: -6.5900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2074
    Cell Significance Index: -2.9700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2140
    Cell Significance Index: -5.5000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2213
    Cell Significance Index: -5.8200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2328
    Cell Significance Index: -5.0300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.2354
    Cell Significance Index: -2.9200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2355
    Cell Significance Index: -8.2500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2377
    Cell Significance Index: -12.0100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** SNAPC4 exhibits several key characteristics that highlight its importance in RNA processing and gene regulation: 1. **Tissue-specific expression**: SNAPC4 is predominantly expressed in neurons and epithelial cells, suggesting its involvement in specific cellular processes. 2. **SnRNP complex subunit**: SNAPC4 is a subunit of the snRNP complex, which is essential for the assembly and activation of snRNAs. 3. **RNA polymerase II interaction**: SNAPC4 interacts with RNA polymerase II, a key enzyme responsible for transcription, indicating its role in regulating gene expression. 4. **Diverse cellular contexts**: SNAPC4 is expressed in various cell types, including L5 extratelencephalic projecting glutamatergic cortical neurons, choroid plexus epithelial cells, and intestinal epithelial cells, highlighting its broad functional significance. **Pathways and Functions** SNAPC4 is involved in several key pathways and functions, including: 1. **Gene expression regulation**: SNAPC4 collaborates with RNA polymerase II to regulate gene expression, particularly in neurons and epithelial cells. 2. **SnRNA processing**: SNAPC4 is essential for the assembly and activation of snRNAs, which are critical for various RNA processing events, including splicing and transcription. 3. **Transcription initiation**: SNAPC4 interacts with RNA polymerase III, facilitating the initiation of transcription from type 3 promoters. 4. **Nucleus organization**: SNAPC4 contributes to the organization of the nucleus, influencing the localization and function of snRNPs. **Clinical Significance** The dysregulation of SNAPC4 has significant implications for various diseases, including: 1. **Neurological disorders**: Alterations in SNAPC4 expression or function may contribute to neurological disorders, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). 2. **Cancer**: Dysregulation of SNAPC4 has been linked to certain types of cancer, including colon cancer, where it may contribute to tumorigenesis and cancer progression. 3. **Epithelial disorders**: SNAPC4 expression and function may be compromised in epithelial disorders, such as inflammatory bowel disease (IBD) and certain types of cancer. 4. **Neurodevelopmental disorders**: Alterations in SNAPC4 expression or function may contribute to neurodevelopmental disorders, such as autism spectrum disorder (ASD). In conclusion, SNAPC4 is a critical component of the snRNP complex, playing a vital role in regulating gene expression and maintaining cellular homeostasis. Its dysregulation has significant implications for various diseases, highlighting the need for further research into the molecular mechanisms underlying SNAPC4 function and its clinical significance.

Genular Protein ID: 1212419845

Symbol: SNPC4_HUMAN

Name: snRNA-activating protein complex subunit 4

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9418884

Title: The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1.

PubMed ID: 9418884

DOI: 10.1128/mcb.18.1.368

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 11056176

Title: A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc.

PubMed ID: 11056176

DOI: 10.1074/jbc.m009301200

PubMed ID: 12621023

Title: The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition.

PubMed ID: 12621023

DOI: 10.1074/jbc.m204247200

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 36965478

Title: Bi-allelic SNAPC4 variants dysregulate global alternative splicing and lead to neuroregression and progressive spastic paraparesis.

PubMed ID: 36965478

DOI: 10.1016/j.ajhg.2023.03.001

Sequence Information:

  • Length: 1469
  • Mass: 159433
  • Checksum: 78CBCFB1887E106C
  • Sequence:
  • MDVDAEREKI TQEIKELERI LDPGSSGSHV EISESSLESD SEADSLPSED LDPADPPISE 
    EERWGEASND EDDPKDKTLP EDPETCLQLN MVYQEVIQEK LAEANLLLAQ NREQQEELMR 
    DLAGSKGTKV KDGKSLPPST YMGHFMKPYF KDKVTGVGPP ANEDTREKAA QGIKAFEELL 
    VTKWKNWEKA LLRKSVVSDR LQRLLQPKLL KLEYLHQKQS KVSSELERQA LEKQGREAEK 
    EIQDINQLPE EALLGNRLDS HDWEKISNIN FEGSRSAEEI RKFWQNSEHP SINKQEWSRE 
    EEERLQAIAA AHGHLEWQKI AEELGTSRSA FQCLQKFQQH NKALKRKEWT EEEDRMLTQL 
    VQEMRVGSHI PYRRIVYYME GRDSMQLIYR WTKSLDPGLK KGYWAPEEDA KLLQAVAKYG 
    EQDWFKIREE VPGRSDAQCR DRYLRRLHFS LKKGRWNLKE EEQLIELIEK YGVGHWAKIA 
    SELPHRSGSQ CLSKWKIMMG KKQGLRRRRR RARHSVRWSS TSSSGSSSGS SGGSSSSSSS 
    SSEEDEPEQA QAGEGDRALL SPQYMVPDMD LWVPARQSTS QPWRGGAGAW LGGPAASLSP 
    PKGSSASQGG SKEASTTAAA PGEETSPVQV PARAHGPVPR SAQASHSADT RPAGAEKQAL 
    EGGRRLLTVP VETVLRVLRA NTAARSCTQK EQLRQPPLPT SSPGVSSGDS VARSHVQWLR 
    HRATQSGQRR WRHALHRRLL NRRLLLAVTP WVGDVVVPCT QASQRPAVVQ TQADGLREQL 
    QQARLASTPV FTLFTQLFHI DTAGCLEVVR ERKALPPRLP QAGARDPPVH LLQASSSAQS 
    TPGHLFPNVP AQEASKSASH KGSRRLASSR VERTLPQASL LASTGPRPKP KTVSELLQEK 
    RLQEARAREA TRGPVVLPSQ LLVSSSVILQ PPLPHTPHGR PAPGPTVLNV PLSGPGAPAA 
    AKPGTSGSWQ EAGTSAKDKR LSTMQALPLA PVFSEAEGTA PAASQAPALG PGQISVSCPE 
    SGLGQSQAPA ASRKQGLPEA PPFLPAAPSP TPLPVQPLSL THIGGPHVAT SVPLPVTWVL 
    TAQGLLPVPV PAVVSLPRPA GTPGPAGLLA TLLPPLTETR AAQGPRAPAL SSSWQPPANM 
    NREPEPSCRT DTPAPPTHAL SQSPAEADGS VAFVPGEAQV AREIPEPRTS SHADPPEAEP 
    PWSGRLPAFG GVIPATEPRG TPGSPSGTQE PRGPLGLEKL PLRQPGPEKG ALDLEKPPLP 
    QPGPEKGALD LGLLSQEGEA ATQQWLGGQR GVRVPLLGSR LPYQPPALCS LRALSGLLLH 
    KKALEHKATS LVVGGEAERP AGALQASLGL VRGQLQDNPA YLLLRARFLA AFTLPALLAT 
    LAPQGVRTTL SVPSRVGSES EDEDLLSELE LADRDGQPGC TTATCPIQGA PDSGKCSASS 
    CLDTSNDPDD LDVLRTRHAR HTRKRRRLV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.