Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 234.2084
Cell Significance Index: -36.4300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 139.4478
Cell Significance Index: -35.3700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 91.9777
Cell Significance Index: -37.8900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 85.3698
Cell Significance Index: -40.3100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 84.9954
Cell Significance Index: -34.5300 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 76.2658
Cell Significance Index: -39.2300 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 60.2588
Cell Significance Index: -40.4400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 31.5989
Cell Significance Index: -38.9600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 12.4941
Cell Significance Index: -33.4700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 10.1494
Cell Significance Index: -40.0500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 9.8831
Cell Significance Index: -21.6300 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 9.1064
Cell Significance Index: -27.9700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.3970
Cell Significance Index: 19.0600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.1745
Cell Significance Index: 116.1800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.1097
Cell Significance Index: 29.6300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.0875
Cell Significance Index: 29.6000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.0524
Cell Significance Index: 63.1800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.9981
Cell Significance Index: 108.5700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.9540
Cell Significance Index: 44.4800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.9306
Cell Significance Index: 69.3600 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.9214
Cell Significance Index: 119.0400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8429
Cell Significance Index: 137.0900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.8153
Cell Significance Index: 161.7900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.7984
Cell Significance Index: 160.1500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.7124
Cell Significance Index: 33.4800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.6953
Cell Significance Index: 95.4800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.6882
Cell Significance Index: 14.9100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.6679
Cell Significance Index: 13.9800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.5923
Cell Significance Index: 17.0700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.5551
Cell Significance Index: 35.8200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.5299
Cell Significance Index: 15.1900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5129
Cell Significance Index: 23.2500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.4226
Cell Significance Index: 51.9600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4186
Cell Significance Index: 228.5900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.3990
Cell Significance Index: 20.9500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.3888
Cell Significance Index: 139.4600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.3725
Cell Significance Index: 164.6700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.3269
Cell Significance Index: 38.5500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.2994
Cell Significance Index: 22.9800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2985
Cell Significance Index: 53.8200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2963
Cell Significance Index: 15.3900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.2864
Cell Significance Index: 198.1000 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2841
Cell Significance Index: 36.4200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.2315
Cell Significance Index: 5.9500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2069
Cell Significance Index: 39.3800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.1633
Cell Significance Index: 8.5100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1556
Cell Significance Index: 10.7600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.1302
Cell Significance Index: 9.2100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1248
Cell Significance Index: 21.3100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1205
Cell Significance Index: 4.2400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0984
Cell Significance Index: 2.7500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0485
Cell Significance Index: 91.4000 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.0430
Cell Significance Index: 0.8400 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.0267
Cell Significance Index: 0.4000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0252
Cell Significance Index: 16.0100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0222
Cell Significance Index: 34.2500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0182
Cell Significance Index: 33.6000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0149
Cell Significance Index: 0.2500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0004
Cell Significance Index: -0.5000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0034
Cell Significance Index: -1.5600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0048
Cell Significance Index: -3.6700 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.0184
Cell Significance Index: -0.3200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0345
Cell Significance Index: -25.2900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0402
Cell Significance Index: -5.8500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0448
Cell Significance Index: -33.1500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0490
Cell Significance Index: -5.0100 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0551
Cell Significance Index: -1.4500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0676
Cell Significance Index: -38.1300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0689
Cell Significance Index: -43.0100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1086
Cell Significance Index: -6.8500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1136
Cell Significance Index: -32.7000 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1193
Cell Significance Index: -2.5400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1461
Cell Significance Index: -3.9100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1544
Cell Significance Index: -4.9500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1565
Cell Significance Index: -5.4400 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.1620
Cell Significance Index: -2.4600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1806
Cell Significance Index: -5.3100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1896
Cell Significance Index: -10.6400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2099
Cell Significance Index: -44.2100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2222
Cell Significance Index: -25.8900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2455
Cell Significance Index: -28.1300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2985
Cell Significance Index: -20.0700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.3103
Cell Significance Index: -19.0800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3403
Cell Significance Index: -35.4300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.3805
Cell Significance Index: -9.7200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.4264
Cell Significance Index: -18.8600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4409
Cell Significance Index: -34.9200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4989
Cell Significance Index: -30.5900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.5633
Cell Significance Index: -21.3300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.5765
Cell Significance Index: -9.8800 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.5810
Cell Significance Index: -5.3500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.5912
Cell Significance Index: -15.8200 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.6288
Cell Significance Index: -13.4400 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.6503
Cell Significance Index: -7.0700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.6717
Cell Significance Index: -16.7900 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.7164
Cell Significance Index: -36.2000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.7282
Cell Significance Index: -8.6800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.7502
Cell Significance Index: -11.0800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.8040
Cell Significance Index: -14.8600 - Cell Name: peg cell (CL4033014)
Fold Change: -0.8237
Cell Significance Index: -19.0300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2993981762
Symbol: STX5_HUMAN
Name: Syntaxin-5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9188044
Title: Cloning and identification of human syntaxin 5 as a synaptobrevin/VAMP binding protein.
PubMed ID: 9188044
DOI: 10.1007/bf02736780
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19536132
Title: Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing.
PubMed ID: 19536132
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23701949
Title: Stx5 is a novel interactor of VLDL-R to affect its intracellular trafficking and processing.
PubMed ID: 23701949
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 27795424
Title: Potent Inhibition of Human Cytomegalovirus by Modulation of Cellular SNARE Syntaxin 5.
PubMed ID: 27795424
DOI: 10.1128/jvi.01637-16
PubMed ID: 34779586
Title: BET1 variants establish impaired vesicular transport as a cause for muscular dystrophy with epilepsy.
PubMed ID: 34779586
PubMed ID: 18843296
Title: Structural basis of cargo membrane protein discrimination by the human COPII coat machinery.
PubMed ID: 18843296
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 29463886
Title: A set of regulatory genes co-expressed in embryonic human brain is implicated in disrupted speech development.
PubMed ID: 29463886
PubMed ID: 34711829
Title: Congenital disorder of glycosylation caused by starting site-specific variant in syntaxin-5.
PubMed ID: 34711829
Sequence Information:
- Length: 355
- Mass: 39673
- Checksum: EE8616A226888501
- Sequence:
MIPRKRYGSK NTDQGVYLGL SKTQVLSPAT AGSSSSDIAP LPPPVTLVPP PPDTMSCRDR TQEFLSACKS LQTRQNGIQT NKPALRAVRQ RSEFTLMAKR IGKDLSNTFA KLEKLTILAK RKSLFDDKAV EIEELTYIIK QDINSLNKQI AQLQDFVRAK GSQSGRHLQT HSNTIVVSLQ SKLASMSNDF KSVLEVRTEN LKQQRSRREQ FSRAPVSALP LAPNHLGGGA VVLGAESHAS KDVAIDMMDS RTSQQLQLID EQDSYIQSRA DTMQNIESTI VELGSIFQQL AHMVKEQEET IQRIDENVLG AQLDVEAAHS EILKYFQSVT SNRWLMVKIF LILIVFFIIF VVFLA
Genular Protein ID: 2876114290
Symbol: B4DKR0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
Sequence Information:
- Length: 259
- Mass: 29234
- Checksum: A68A11B6122D7950
- Sequence:
MAKRIGKDLS NTFAKLEKLT ILAKRKSLFD DKAVEIEELT YIIKQDINSL NKQIAQLQDF VRAKGSQSGR HLQTHSNTIV VSLQSKLASM SNDFKSVLEV RTENLKQQRS RREQFSRAPV SALPLAPNHL GGGAVVLGAE SHASKDVAID MMDSRTSQQL QLIDEQDSYI QSRADTMQNI ESTIVELGSI FQQLAHMVKE QEETIQRIDE NVLGAQLDVE AAHSEILKYF QSVTSNRWLM VKIFLILIVF FIIFVVFLA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.