Details for: SUPV3L1

Gene ID: 6832

Symbol: SUPV3L1

Ensembl ID: ENSG00000156502

Description: Suv3 like RNA helicase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 129.9943
    Cell Significance Index: -20.2200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 80.2702
    Cell Significance Index: -20.3600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 49.1398
    Cell Significance Index: -23.2000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 17.9650
    Cell Significance Index: -22.1500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.5256
    Cell Significance Index: -20.1600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.0753
    Cell Significance Index: -18.6600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.7627
    Cell Significance Index: -22.7400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.1619
    Cell Significance Index: -6.9200
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 2.9274
    Cell Significance Index: 48.2400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.1160
    Cell Significance Index: 223.8700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8312
    Cell Significance Index: 90.4100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7761
    Cell Significance Index: 46.5900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7494
    Cell Significance Index: 121.8900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6708
    Cell Significance Index: 66.3600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5879
    Cell Significance Index: 116.6700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5726
    Cell Significance Index: 205.3900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.5256
    Cell Significance Index: 61.2500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5061
    Cell Significance Index: 22.9400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.3973
    Cell Significance Index: 30.4900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3814
    Cell Significance Index: 10.6600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3496
    Cell Significance Index: 315.6400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3189
    Cell Significance Index: 220.5800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.3177
    Cell Significance Index: 12.0300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.3044
    Cell Significance Index: 7.8300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2950
    Cell Significance Index: 13.0500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2678
    Cell Significance Index: 48.2800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2552
    Cell Significance Index: 14.3200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2272
    Cell Significance Index: 15.7100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2231
    Cell Significance Index: 30.6400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2151
    Cell Significance Index: 4.6600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1988
    Cell Significance Index: 12.5300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1924
    Cell Significance Index: 85.0500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1742
    Cell Significance Index: 33.1600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.1723
    Cell Significance Index: 4.6000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1709
    Cell Significance Index: 8.8800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1565
    Cell Significance Index: 18.4600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1363
    Cell Significance Index: 8.3800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1207
    Cell Significance Index: 7.7900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1197
    Cell Significance Index: 15.4700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1187
    Cell Significance Index: 64.8300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1183
    Cell Significance Index: 3.1700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1170
    Cell Significance Index: 5.5000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1106
    Cell Significance Index: 13.6000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1069
    Cell Significance Index: 7.1900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1003
    Cell Significance Index: 2.7300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0930
    Cell Significance Index: 6.5800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0865
    Cell Significance Index: 54.9200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0753
    Cell Significance Index: 2.1700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0686
    Cell Significance Index: 3.2000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0661
    Cell Significance Index: 124.4700
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.0635
    Cell Significance Index: 0.9100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0209
    Cell Significance Index: 38.5900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0181
    Cell Significance Index: 27.8000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0117
    Cell Significance Index: 5.2900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0072
    Cell Significance Index: 9.7500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0004
    Cell Significance Index: 0.0500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0011
    Cell Significance Index: -0.0400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0108
    Cell Significance Index: -1.5700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0126
    Cell Significance Index: -9.2400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0191
    Cell Significance Index: -1.4200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0194
    Cell Significance Index: -3.3100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0234
    Cell Significance Index: -17.3300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0234
    Cell Significance Index: -17.7100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0349
    Cell Significance Index: -19.7100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0390
    Cell Significance Index: -0.8300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0406
    Cell Significance Index: -25.3500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0504
    Cell Significance Index: -5.1500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0510
    Cell Significance Index: -1.6400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0549
    Cell Significance Index: -0.9400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0659
    Cell Significance Index: -18.9600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0676
    Cell Significance Index: -3.5500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0719
    Cell Significance Index: -2.0600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0844
    Cell Significance Index: -9.6800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1030
    Cell Significance Index: -3.5800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1055
    Cell Significance Index: -1.7700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1163
    Cell Significance Index: -24.5000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1185
    Cell Significance Index: -3.1200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1269
    Cell Significance Index: -3.6200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1481
    Cell Significance Index: -2.0200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1645
    Cell Significance Index: -4.8300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1754
    Cell Significance Index: -2.5900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1799
    Cell Significance Index: -18.7300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1843
    Cell Significance Index: -4.4200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2165
    Cell Significance Index: -4.7400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2313
    Cell Significance Index: -4.9500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2462
    Cell Significance Index: -19.5000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2505
    Cell Significance Index: -4.8900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2510
    Cell Significance Index: -15.3900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2852
    Cell Significance Index: -5.9700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2862
    Cell Significance Index: -7.6600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.2935
    Cell Significance Index: -7.1600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3451
    Cell Significance Index: -7.3300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3483
    Cell Significance Index: -17.6000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3667
    Cell Significance Index: -11.6800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.3725
    Cell Significance Index: -4.6200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3817
    Cell Significance Index: -9.7500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3986
    Cell Significance Index: -13.0500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.4149
    Cell Significance Index: -8.3300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4168
    Cell Significance Index: -4.3200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4178
    Cell Significance Index: -4.9800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SUPV3L1 is an ATP-dependent RNA helicase that possesses helicase activity, enabling it to unwind double-stranded RNAs (dsRNAs) and regulate RNA metabolism. Its mitochondrial localization suggests a specialized role in processing and degrading mRNAs within the mitochondria. SUPV3L1 has been shown to interact with various proteins, including other RNA helicases, ATPases, and mitochondrial proteins, further emphasizing its complex molecular interactions. **Pathways and Functions:** SUPV3L1 is involved in several key pathways, including: 1. **Mitochondrial RNA processing**: SUPV3L1 regulates the processing and degradation of mitochondrial mRNAs, ensuring proper mitochondrial function and biogenesis. 2. **RNA degradation**: SUPV3L1 participates in the degradation of dsRNAs, which is essential for maintaining genome stability and preventing the accumulation of toxic RNA species. 3. **Cell growth and proliferation**: SUPV3L1's regulation of mitochondrial RNA metabolism can influence cellular growth and proliferation, particularly in neurons and epithelial cells. 4. **Apoptosis regulation**: SUPV3L1's activity can modulate the apoptotic process, suggesting a role in regulating programmed cell death. 5. **Metabolism of RNAs**: SUPV3L1's involvement in RNA metabolism highlights its potential role in regulating various cellular processes, including translation, splicing, and degradation of RNAs. **Clinical Significance:** Dysregulation of SUPV3L1 has been implicated in various diseases, including: 1. **Neurodegenerative disorders**: Alterations in SUPV3L1 expression have been linked to neurodegenerative diseases, such as Alzheimer's and Parkinson's, where mitochondrial dysfunction is a hallmark. 2. **Cancer**: SUPV3L1's role in regulating mitochondrial RNA metabolism may contribute to cancer development and progression. 3. **Neurodevelopmental disorders**: SUPV3L1's expression in neurons suggests a potential role in neurodevelopmental disorders, such as autism and schizophrenia. In conclusion, SUPV3L1 is a critical component of mitochondrial RNA processing and degradation, playing a significant role in regulating cellular growth, survival, and apoptosis. Further research on SUPV3L1's molecular mechanisms and clinical significance will provide insights into its potential therapeutic applications and the development of novel treatments for diseases associated with mitochondrial dysfunction.

Genular Protein ID: 3966962860

Symbol: SUV3_HUMAN

Name: ATP-dependent RNA helicase SUPV3L1, mitochondrial

UniProtKB Accession Codes:

Q8IYB8 A8K301 O43630

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 8 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 5 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 29 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 Rhea 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10453991

Title: A human putative Suv3-like RNA helicase is conserved between Rhodobacter and all eukaryotes.

PubMed ID: 10453991

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12466530

Title: Localisation of the human hSuv3p helicase in the mitochondrial matrix and its preferential unwinding of dsDNA.

PubMed ID: 12466530

DOI: 10.1093/nar/gkf647

PubMed ID: 12694177

Title: Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses.

PubMed ID: 12694177

DOI: 10.1046/j.1432-1033.2003.03540.x

PubMed ID: 14561097

Title: Potent inhibition of NTPase/helicase of the West Nile Virus by ring-expanded ('fat') nucleoside analogues.

PubMed ID: 14561097

DOI: 10.1021/jm030277k

PubMed ID: 15096047

Title: Purified human SUV3p exhibits multiple-substrate unwinding activity upon conformational change.

PubMed ID: 15096047

DOI: 10.1021/bi0356449

PubMed ID: 16176273

Title: Human ATP-dependent RNA/DNA helicase hSuv3p interacts with the cofactor of survivin HBXIP.

PubMed ID: 16176273

DOI: 10.1111/j.1742-4658.2005.04910.x

PubMed ID: 17352692

Title: Down-regulation of human RNA/DNA helicase SUV3 induces apoptosis by a caspase- and AIF-dependent pathway.

PubMed ID: 17352692

DOI: 10.1042/bc20060108

PubMed ID: 17961633

Title: Interaction of human SUV3 RNA/DNA helicase with BLM helicase; loss of the SUV3 gene results in mouse embryonic lethality.

PubMed ID: 17961633

DOI: 10.1016/j.mad.2007.09.001

PubMed ID: 18063578

Title: The layered structure of human mitochondrial DNA nucleoids.

PubMed ID: 18063578

DOI: 10.1074/jbc.m708444200

PubMed ID: 18678873

Title: Role of SUV3 helicase in maintaining mitochondrial homeostasis in human cells.

PubMed ID: 18678873

DOI: 10.1074/jbc.m802991200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19509288

Title: Human mitochondrial SUV3 and polynucleotide phosphorylase form a 330-kDa heteropentamer to cooperatively degrade double-stranded RNA with a 3'-to-5' directionality.

PubMed ID: 19509288

DOI: 10.1074/jbc.m109.009605

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 19864255

Title: Human mitochondrial RNA turnover caught in flagranti: involvement of hSuv3p helicase in RNA surveillance.

PubMed ID: 19864255

DOI: 10.1093/nar/gkp903

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29967381

Title: Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria.

PubMed ID: 29967381

DOI: 10.1038/s41467-018-05007-9

Sequence Information:

  • Length: 786
  • Mass: 87991
  • Checksum: FD3BC8EC64C23E42
  • Sequence:
    • MSFSRALLWA RLPAGRQAGH RAAICSALRP HFGPFPGVLG QVSVLATASS SASGGSKIPN 
TSLFVPLTVK PQGPSADGDV GAELTRPLDK NEVKKVLDKF YKRKEIQKLG ADYGLDARLF 
HQAFISFRNY IMQSHSLDVD IHIVLNDICF GAAHADDLFP FFLRHAKQIF PVLDCKDDLR 
KISDLRIPPN WYPDARAMQR KIIFHSGPTN SGKTYHAIQK YFSAKSGVYC GPLKLLAHEI 
FEKSNAAGVP CDLVTGEERV TVQPNGKQAS HVSCTVEMCS VTTPYEVAVI DEIQMIRDPA 
RGWAWTRALL GLCAEEVHLC GEPAAIDLVM ELMYTTGEEV EVRDYKRLTP ISVLDHALES 
LDNLRPGDCI VCFSKNDIYS VSRQIEIRGL ESAVIYGSLP PGTKLAQAKK FNDPNDPCKI 
LVATDAIGMG LNLSIRRIIF YSLIKPSINE KGERELEPIT TSQALQIAGR AGRFSSRFKE 
GEVTTMNHED LSLLKEILKR PVDPIRAAGL HPTAEQIEMF AYHLPDATLS NLIDIFVDFS 
QVDGQYFVCN MDDFKFSAEL IQHIPLSLRV RYVFCTAPIN KKQPFVCSSL LQFARQYSRN 
EPLTFAWLRR YIKWPLLPPK NIKDLMDLEA VHDVLDLYLW LSYRFMDMFP DASLIRDLQK 
ELDGIIQDGV HNITKLIKMS ETHKLLNLEG FPSGSQSRLS GTLKSQARRT RGTKALGSKA 
TEPPSPDAGE LSLASRLVQQ GLLTPDMLKQ LEKEWMTQQT EHNKEKTESG THPKGTRRKK 
KEPDSD

Genular Protein ID: 1712868902

Symbol: B7Z611_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z611

Database IDs:

ARBA 15 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 7 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 7 Gene3D 4 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 5 RefSeq 1 Rhea 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 631
  • Mass: 71103
  • Checksum: 6B88E8213DA64101
  • Sequence:
    • MQSHSLDVDI HIVLNDICFG AAHADDLFPF FLRHAKQIFP VLDCKDDLRK ISDLRIPPNW 
YPDARAMQRK IIFHSGPTNS GKTYHAIQKY FSAKSGVYCG PPKLLAHEIF EKSNAAGVPC 
DLVTGEERVT VQPNGKQASH VSCTVEMCSV TTPYEVAVID EIQMIRDPAR GWAWTRALLG 
LCAEEVHLCG EPAAIDLVME LMYTTGEEVE VRDYKRLTPI SVLDHALESL DNLRPGDCIV 
CFSKNDIYSV SRQIEIRGLE SAVIYGSLPP GTKLAQAKKF NDPNDPCKIL VATDAIGMGL 
NLSIRRIIFY SLIKPSINEK GERELEPITT SQALQIAGRA GRFSSRFKEG EVTTMNHEDL 
SLLKEILKRP VDPIRAAGLH PTAEQIEMFA YHLPDATLSN LIDIFVDFSQ VDGQYFVCNM 
DDFKFSAELI QHIPLSLRVR YVFCTAPINK KQPFVCSSLL QFARQYSRNE PLTFAWLRRY 
IKWPLLPPKN IKDLMDLEAV HDVLDLYLWL SYRFMDMFPD ASLIRDLQKE LDGIIQDGVH 
NITKLIKMSE THKLLNLEGF PSGSQSRLSG TLKSQARRTR GTKALGSKAT EPPSPDAGEL 
SLASRLVQQG LLTPDMLKQL EKEWMTQQTE H

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.