Details for: TAPBP

Gene ID: 6892

Symbol: TAPBP

Ensembl ID: ENSG00000231925

Description: TAP binding protein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 338.0367
    Cell Significance Index: -52.5800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 168.8986
    Cell Significance Index: -42.8400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 154.6681
    Cell Significance Index: -62.8400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 145.8096
    Cell Significance Index: -68.8400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 135.2099
    Cell Significance Index: -69.5500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 102.8282
    Cell Significance Index: -69.0000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 66.0492
    Cell Significance Index: -63.0600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 44.9408
    Cell Significance Index: -55.4100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 18.1066
    Cell Significance Index: -48.5100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 14.4068
    Cell Significance Index: -56.8500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.7859
    Cell Significance Index: -36.2000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.6011
    Cell Significance Index: -25.3900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 3.4199
    Cell Significance Index: 556.2100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.7409
    Cell Significance Index: 50.6600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.9768
    Cell Significance Index: 127.5300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.7015
    Cell Significance Index: 19.3300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.6945
    Cell Significance Index: 184.3100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.6859
    Cell Significance Index: 207.3000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.6459
    Cell Significance Index: 44.8000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.5575
    Cell Significance Index: 73.2000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.4873
    Cell Significance Index: 268.1100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.4623
    Cell Significance Index: 68.1800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.4077
    Cell Significance Index: 39.3400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.3741
    Cell Significance Index: 40.3600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.2310
    Cell Significance Index: 1111.4800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.1289
    Cell Significance Index: 133.1400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.0400
    Cell Significance Index: 567.9800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.0239
    Cell Significance Index: 53.1900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.9973
    Cell Significance Index: 24.9300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.9895
    Cell Significance Index: 97.8800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.9638
    Cell Significance Index: 193.3300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.9475
    Cell Significance Index: 418.9200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.9235
    Cell Significance Index: 68.8300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.8410
    Cell Significance Index: 107.8100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.8281
    Cell Significance Index: 157.5900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.8177
    Cell Significance Index: 105.6400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7849
    Cell Significance Index: 107.7900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7035
    Cell Significance Index: 20.2700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.6560
    Cell Significance Index: 15.1600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5954
    Cell Significance Index: 118.1600
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.5748
    Cell Significance Index: 8.7300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.4805
    Cell Significance Index: 33.9900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.3738
    Cell Significance Index: 18.8900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1995
    Cell Significance Index: 34.0600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1311
    Cell Significance Index: 6.8300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1228
    Cell Significance Index: 84.9400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1180
    Cell Significance Index: 5.3500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1044
    Cell Significance Index: 37.4300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0366
    Cell Significance Index: 27.7000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0234
    Cell Significance Index: 44.1100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0011
    Cell Significance Index: -1.9600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0094
    Cell Significance Index: -14.4100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.0280
    Cell Significance Index: -0.5000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0326
    Cell Significance Index: -3.3300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0342
    Cell Significance Index: -25.3600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0473
    Cell Significance Index: -29.5500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0488
    Cell Significance Index: -66.4200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0549
    Cell Significance Index: -40.2300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0573
    Cell Significance Index: -36.3800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0573
    Cell Significance Index: -1.5300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0663
    Cell Significance Index: -37.4200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0975
    Cell Significance Index: -44.2400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1559
    Cell Significance Index: -17.8600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1581
    Cell Significance Index: -33.3000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1730
    Cell Significance Index: -4.9600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1847
    Cell Significance Index: -21.5200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1921
    Cell Significance Index: -27.9300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1989
    Cell Significance Index: -6.9900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2171
    Cell Significance Index: -62.4700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2416
    Cell Significance Index: -5.1500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3396
    Cell Significance Index: -17.8300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3489
    Cell Significance Index: -21.9900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.3671
    Cell Significance Index: -5.5000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3792
    Cell Significance Index: -29.1000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3951
    Cell Significance Index: -10.3900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.4029
    Cell Significance Index: -3.7100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.4205
    Cell Significance Index: -29.0800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4265
    Cell Significance Index: -48.6900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4324
    Cell Significance Index: -5.9000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.4512
    Cell Significance Index: -27.0900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.4603
    Cell Significance Index: -11.7600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.4671
    Cell Significance Index: -10.1200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4814
    Cell Significance Index: -15.4200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5337
    Cell Significance Index: -55.5700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.6089
    Cell Significance Index: -34.1700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.6845
    Cell Significance Index: -13.3600
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.6960
    Cell Significance Index: -28.5200
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.6986
    Cell Significance Index: -7.2300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.7200
    Cell Significance Index: -12.0500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7324
    Cell Significance Index: -32.4000
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.7638
    Cell Significance Index: -4.9800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8434
    Cell Significance Index: -66.8000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.9132
    Cell Significance Index: -34.5800
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.9445
    Cell Significance Index: -13.4200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9677
    Cell Significance Index: -59.3300
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.9832
    Cell Significance Index: -16.9500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.0545
    Cell Significance Index: -27.1100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.1193
    Cell Significance Index: -39.2100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.1402
    Cell Significance Index: -19.5400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.2004
    Cell Significance Index: -38.2300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Molecular Chaperone Function:** TAPBP acts as a molecular chaperone, facilitating the proper folding and assembly of MHC I molecules. 2. **Peptide Loading:** TAPBP is essential for the loading of endogenously synthesized peptides onto MHC I molecules. 3. **Endoplasmic Reticulum (ER) Association:** TAPBP is primarily localized to the ER, where it interacts with other ER-resident proteins to facilitate antigen processing. 4. **Cellular Expression:** TAPBP is expressed in various immune cells, including monocytes, dendritic cells, and T cells. 5. **Regulatory Role:** TAPBP modulates the stability and function of MHC I molecules, influencing the efficiency of antigen presentation. **Pathways and Functions:** 1. **Antigen Presentation:** TAPBP is integral to the MHC I-mediated antigen presentation pathway, ensuring the proper loading of peptides onto MHC I molecules. 2. **Endoplasmic Reticulum-Golgi Intermediate Compartment (ER-GiC) Pathway:** TAPBP interacts with other ER-GiC proteins to facilitate the transport of MHC I molecules to the Golgi apparatus. 3. **Tap1 and Tap2 Binding:** TAPBP interacts with Tap1 and Tap2, which are essential for the assembly and loading of peptides onto MHC I molecules. 4. **Peptide Antigen Assembly:** TAPBP facilitates the assembly of peptides onto MHC I molecules, ensuring optimal antigen presentation. 5. **Regulation of Gene Expression and Protein Complex Stability:** TAPBP modulates the expression of MHC I genes and regulates the stability of MHC I protein complexes. **Clinical Significance:** 1. **Immunotherapy and Vaccine Development:** Understanding the mechanisms of TAPBP-mediated antigen presentation can inform the design of novel immunotherapies and vaccines targeting CD8+ T cells. 2. **Cancer Immunotherapy:** TAPBP's role in antigen presentation makes it an attractive target for cancer immunotherapies, such as checkpoint inhibitors. 3. **Autoimmune Diseases:** Dysregulation of TAPBP-mediated antigen presentation may contribute to autoimmune diseases, such as multiple sclerosis and type 1 diabetes. 4. **Infectious Diseases:** TAPBP's function in antigen presentation may influence the efficacy of vaccines against infectious diseases, such as HIV and influenza. In conclusion, TAPBP is a critical component of the MHC I antigen presentation pathway, playing a pivotal role in the efficient presentation of antigens to CD8+ T cells. Further research on TAPBP's mechanisms and clinical implications will provide valuable insights into the development of novel immunotherapies and vaccines.

Genular Protein ID: 964628426

Symbol: TPSN_HUMAN

Name: NGS-17

UniProtKB Accession Codes:

O15533 A2AB91 A2ABC0 B0V003 B0V0A6 B2ZUA4 E9PGM2 O15210 O15272 Q5STJ8 Q5STK6 Q5STQ5 Q5STQ6 Q66K65 Q96KK7 Q9HAN8 Q9UEE0 Q9UEE4 Q9UIZ6 Q9Y6K2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CPTC 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DNASU 1 DisGeNET 1 EMBL 18 EMDB 2 Ensembl 13 EvolutionaryTrace 1 ExpressionAtlas 1 GO 25 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 2 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9238042

Title: Cloning and functional characterization of a subunit of the transporter associated with antigen processing.

PubMed ID: 9238042

DOI: 10.1073/pnas.94.16.8708

PubMed ID: 9271576

Title: A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes.

PubMed ID: 9271576

DOI: 10.1126/science.277.5330.1306

PubMed ID: 9521053

Title: Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC.

PubMed ID: 9521053

DOI: 10.1002/(sici)1521-4141(199802)28:02<459::aid-immu459>3.0.co;2-z

PubMed ID: 9545376

Title: TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC.

PubMed ID: 9545376

DOI: 10.1006/jmbi.1998.1637

PubMed ID: 9802609

Title: Polymorphism of TAPASIN and its linkage disequilibria with HLA class II genes in the Japanese population.

PubMed ID: 9802609

DOI: 10.1111/j.1399-0039.1998.tb03044.x

PubMed ID: 10088603

Title: Granulocyte-macrophage colony-stimulating factor modulates tapasin expression in human neutrophils.

PubMed ID: 10088603

DOI: 10.1002/jlb.65.2.205

PubMed ID: 14668790

Title: Generation of a functional, soluble tapasin protein from an alternatively spliced mRNA.

PubMed ID: 14668790

DOI: 10.1038/sj.gene.6364043

PubMed ID: 20600451

Title: Identification of an alternate splice form of tapasin in human melanoma.

PubMed ID: 20600451

DOI: 10.1016/j.humimm.2010.05.019

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10382748

Title: The N-terminal region of tapasin is required to stabilize the MHC class I loading complex.

PubMed ID: 10382748

DOI: 10.1002/(sici)1521-4141(199906)29:06<1858::aid-immu1858>3.0.co;2-c

PubMed ID: 10636848

Title: Tapasin is required for efficient peptide binding to transporter associated with antigen processing.

PubMed ID: 10636848

DOI: 10.1074/jbc.275.3.1581

PubMed ID: 12582157

Title: An essential function of tapasin in quality control of HLA-G molecules.

PubMed ID: 12582157

DOI: 10.1074/jbc.m212882200

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21263072

Title: Distinct functions for the glycans of tapasin and heavy chains in the assembly of MHC class I molecules.

PubMed ID: 21263072

DOI: 10.4049/jimmunol.1002959

PubMed ID: 22638925

Title: Direct evidence that the N-terminal extensions of the TAP complex act as autonomous interaction scaffolds for the assembly of the MHC I peptide-loading complex.

PubMed ID: 22638925

DOI: 10.1007/s00018-012-1005-6

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 26611325

Title: Assembly of the MHC I peptide-loading complex determined by a conserved ionic lock-switch.

PubMed ID: 26611325

DOI: 10.1038/srep17341

PubMed ID: 19119025

Title: Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer.

PubMed ID: 19119025

DOI: 10.1016/j.immuni.2008.10.018

PubMed ID: 12149238

Title: A subject with a novel type I bare lymphocyte syndrome has tapasin deficiency due to deletion of 4 exons by Alu-mediated recombination.

PubMed ID: 12149238

DOI: 10.1182/blood-2001-12-0252

Sequence Information:

  • Length: 448
  • Mass: 47571
  • Checksum: 9F7BF490BA148B08
  • Sequence:
    • MKSLSLLLAV ALGLATAVSA GPAVIECWFV EDASGKGLAK RPGALLLRQG PGEPPPRPDL 
DPELYLSVHD PAGALQAAFR RYPRGAPAPH CEMSRFVPLP ASAKWASGLT PAQNCPRALD 
GAWLMVSISS PVLSLSSLLR PQPEPQQEPV LITMATVVLT VLTHTPAPRV RLGQDALLDL 
SFAYMPPTSE AASSLAPGPP PFGLEWRRQH LGKGHLLLAA TPGLNGQMPA AQEGAVAFAA 
WDDDEPWGPW TGNGTFWLPT VQPFQEGTYL ATIHLPYLQG QVTLELAVYK PPKVSLMPAT 
LARAAPGEAP PELLCLVSHF YPSGGLEVEW ELRGGPGGRS QKAEGQRWLS ALRHHSDGSV 
SLSGHLQPPP VTTEQHGARY ACRIHHPSLP ASGRSAEVTL EVAGLSGPSL EDSVGLFLSA 
FLLLGLFKAL GWAAVYLSTC KDSKKKAE

Genular Protein ID: 1115298187

Symbol: A0A0A0MT98_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MT98

Database IDs:

ARBA 7 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 3 ExpressionAtlas 1 GO 1 Gene3D 1 HGNC 1 HOGENOM 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 Proteomes 3 ProteomicsDB 1 RefSeq 1 SAM 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 361
  • Mass: 38310
  • Checksum: 0C720A29CCAD4E48
  • Sequence:
    • MKSLSLLLAV ALGLATAVSA GPAVIECWFV EDASGKGLAK RPGALLLRQG PGEPPPRPDL 
DPELYLSVHV VLTVLTHTPA PRVRLGQDAL LDLSFAYMPP TSEAASSLAP GPPPFGLEWR 
RQHLGKGHLL LAATPGLNGQ MPAAQEGAVA FAAWDDDEPW GPWTGNGTFW LPTVQPFQEG 
TYLATIHLPY LQGQVTLELA VYKPPKVSLM PATLARAAPG EAPPELLCLV SHFYPSGGLE 
VEWELRGGPG GRSQKAEGQR WLSALRHHSD GSVSLSGHLQ PPPVTTEQHG ARYACRIHHP 
SLPASGRSAE VTLEVAGLSG PSLEDSVGLF LSAFLLLGLF KALGWAAVYL STCKDSKKKA 
E

Genular Protein ID: 2244590982

Symbol: A0A0A0MSV9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MSV9

Database IDs:

ARBA 7 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 3 ExpressionAtlas 1 GO 2 Gene3D 1 HGNC 1 InterPro 6 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 1 Proteomes 3 ProteomicsDB 1 RefSeq 1 SAM 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 504
  • Mass: 53888
  • Checksum: 7D50630643B69732
  • Sequence:
    • MKSLSLLLAV ALGLATAVSA GPAVIECWFV EDASGKGLAK RPGALLLRQG PGEPPPRPDL 
DPELYLSVHD PAGALQAAFR RYPRGAPAPH CEMSRFVPLP ASAKWASGLT PAQNCPRALD 
GAWLMVSISS PVLSLSSLLR PQPEPQQEPV LITMATVVLT VLTHTPAPRV RLGQDALLDL 
SFAYMPPTSE AASSLAPGPP PFGLEWRRQH LGKGHLLLAA TPGLNGQMPA AQEGAVAFAA 
WDDDEPWGPW TGNGTFWLPT VQPFQEGTYL ATIHLPYLQG QVTLELAVYK PPKVSLMPAT 
LARAAPGEAP PELLCLVSHF YPSGGLEVEW ELRGGPGGRS QKAEGQRWLS ALRHHSDGSV 
SLSGHLQPPP VTTEQHGARY ACRIHHPSLP ASGRSAEVTL EVAGLSGPSL EDSVGLFLSA 
FLLLGLFKAL GWAAVYLSTC KDSKKVQCST SLYLSLVTLS PHPISKPMEG GCWCGRQNLG 
LEFTLIWVKT WHYILTVGLF EHAT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.