Details for: TFE3

Gene ID: 7030

Symbol: TFE3

Ensembl ID: ENSG00000068323

Description: transcription factor binding to IGHM enhancer 3

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 1.88
    Marker Score: 1503
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 1.01
    Marker Score: 4195
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71744
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47969
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30400
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.97
    Marker Score: 683
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2401
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.93
    Marker Score: 480
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.92
    Marker Score: 435
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2712
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5252
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.86
    Marker Score: 4931
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.85
    Marker Score: 307
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.83
    Marker Score: 46676
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 0.78
    Marker Score: 475
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1267
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.77
    Marker Score: 376
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.77
    Marker Score: 12111
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.74
    Marker Score: 296
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.74
    Marker Score: 562.5
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.73
    Marker Score: 24974
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.73
    Marker Score: 651
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.73
    Marker Score: 905
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.73
    Marker Score: 775
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.72
    Marker Score: 373
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.72
    Marker Score: 165
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.72
    Marker Score: 224
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 0.71
    Marker Score: 1388
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.7
    Marker Score: 637
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.68
    Marker Score: 678
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.68
    Marker Score: 2858
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.68
    Marker Score: 449
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 0.67
    Marker Score: 1091.5
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.66
    Marker Score: 170
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.66
    Marker Score: 266
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.65
    Marker Score: 601
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.65
    Marker Score: 699
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.64
    Marker Score: 1605
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.64
    Marker Score: 678
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 0.64
    Marker Score: 366
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.63
    Marker Score: 429
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 0.61
    Marker Score: 3006
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.61
    Marker Score: 196
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.6
    Marker Score: 1418
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6
    Marker Score: 885
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.6
    Marker Score: 1621
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.6
    Marker Score: 147
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.59
    Marker Score: 3569
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.59
    Marker Score: 616
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.59
    Marker Score: 1192
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.58
    Marker Score: 2166
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.58
    Marker Score: 12312
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.58
    Marker Score: 317
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 0.56
    Marker Score: 339
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.55
    Marker Score: 636
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.54
    Marker Score: 837
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.54
    Marker Score: 431
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.53
    Marker Score: 1011
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.51
    Marker Score: 1250
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.51
    Marker Score: 561
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.5
    Marker Score: 294
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.5
    Marker Score: 4280
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 0.5
    Marker Score: 146
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.5
    Marker Score: 274
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.5
    Marker Score: 2141
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 0.49
    Marker Score: 1290
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.49
    Marker Score: 1114
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.48
    Marker Score: 116
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.48
    Marker Score: 230
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.48
    Marker Score: 318
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 0.48
    Marker Score: 108
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 0.48
    Marker Score: 549
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: 0.48
    Marker Score: 165
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.48
    Marker Score: 325
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.47
    Marker Score: 457
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.47
    Marker Score: 284
  • Cell Name: fat cell (CL0000136)
    Fold Change: 0.47
    Marker Score: 264
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.47
    Marker Score: 174
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.47
    Marker Score: 28839
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.47
    Marker Score: 176
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.46
    Marker Score: 4411
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.46
    Marker Score: 1802
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 0.46
    Marker Score: 190
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 0.45
    Marker Score: 2964
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 0.45
    Marker Score: 286.5
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.45
    Marker Score: 157
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.45
    Marker Score: 1866
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 0.44
    Marker Score: 117
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.44
    Marker Score: 181
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.44
    Marker Score: 251
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.44
    Marker Score: 213
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.44
    Marker Score: 705
  • Cell Name: progenitor cell of endocrine pancreas (CL0002351)
    Fold Change: 0.44
    Marker Score: 95
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.44
    Marker Score: 1678
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.43
    Marker Score: 763
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.43
    Marker Score: 874.5
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.43
    Marker Score: 213
  • Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
    Fold Change: 0.43
    Marker Score: 97
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 0.43
    Marker Score: 435
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.43
    Marker Score: 255

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Other Information

**Key Characteristics:** TFE3 is a basic helix-loop-helix (bHLH) transcription factor belonging to the TEA family. It is characterized by its ability to bind to specific DNA sequences, particularly enhancers and promoters, to regulate gene expression. TFE3 is highly expressed in immune cells, such as classical monocytes and CD16-positive monocytes, where it plays a crucial role in regulating immune responses. Additionally, TFE3 is also expressed in non-immune cells, including epithelial cells, where it regulates cellular differentiation and gene expression. **Pathways and Functions:** TFE3 is involved in various signaling pathways, including: 1. **Adaptive Immune Response:** TFE3 regulates the expression of immune genes, including those involved in B cell development and activation, in response to antigen exposure. 2. **Chromatin Remodeling:** TFE3 interacts with chromatin remodeling complexes to regulate gene expression and maintain genome stability. 3. **Cellular Differentiation:** TFE3 regulates the differentiation of immune cells, such as B cells and T cells, and non-immune cells, such as epithelial cells. 4. **Gene Expression:** TFE3 regulates the expression of specific genes involved in immune responses, cellular differentiation, and cellular growth. **Clinical Significance:** TFE3 has been implicated in various diseases, including: 1. **Autoimmune Disorders:** TFE3 has been shown to play a role in the development of autoimmune diseases, such as rheumatoid arthritis and lupus. 2. **Cancer:** TFE3 has been identified as a potential oncogene in certain types of cancer, including lung, breast, and colon cancer. 3. **Neurological Disorders:** TFE3 has been implicated in the pathogenesis of neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, TFE3 is a complex transcription factor that plays a multifaceted role in regulating immune responses, cellular differentiation, and gene expression. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the mechanisms and clinical significance of TFE3. **Future Directions:** 1. **Investigating TFE3's role in disease:** Further studies are needed to elucidate the mechanisms by which TFE3 contributes to disease development and progression. 2. **Developing therapeutic strategies:** Targeting TFE3 or its regulatory pathways may provide novel therapeutic opportunities for treating autoimmune and cancer diseases. 3. **Understanding TFE3's role in cellular differentiation:** Elucidating the mechanisms by which TFE3 regulates cellular differentiation may provide insights into the development of new cell-based therapies.

Genular Protein ID: 485775736

Symbol: TFE3_HUMAN

Name: Class E basic helix-loop-helix protein 33

UniProtKB Accession Codes:

P19532 A8MZL6 Q5JU74 Q92757 Q92758 Q99964

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 23 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 2 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9393982

Title: Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma.

PubMed ID: 9393982

DOI: 10.1038/sj.onc.1201394

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 8986805

Title: Fusion of the transcription factor TFE3 gene to a novel gene, PRCC, in t(X;1)(p11;q21)-positive papillary renal cell carcinomas.

PubMed ID: 8986805

DOI: 10.1073/pnas.93.26.15294

PubMed ID: 8872474

Title: The t(X;1)(p11.2;q21.2) translocation in papillary renal cell carcinoma fuses a novel gene PRCC to the TFE3 transcription factor gene.

PubMed ID: 8872474

DOI: 10.1093/hmg/5.9.1333

PubMed ID: 2338243

Title: TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.

PubMed ID: 2338243

DOI: 10.1101/gad.4.2.167

PubMed ID: 1748288

Title: TFEB has DNA-binding and oligomerization properties of a unique helix-loop-helix/leucine-zipper family.

PubMed ID: 1748288

DOI: 10.1101/gad.5.12a.2342

PubMed ID: 11358836

Title: Fusion of a novel gene, RCC17, to the TFE3 gene in t(X;17)(p11.2;q25.3)-bearing papillary renal cell carcinomas.

PubMed ID: 11358836

PubMed ID: 11244503

Title: The der(17)t(X;17)(p11;q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25.

PubMed ID: 11244503

DOI: 10.1038/sj.onc.1204074

PubMed ID: 15507434

Title: Sumoylation of MITF and its related family members TFE3 and TFEB.

PubMed ID: 15507434

DOI: 10.1074/jbc.m411757200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21209915

Title: Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.

PubMed ID: 21209915

DOI: 10.1371/journal.pone.0015793

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22692423

Title: The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.

PubMed ID: 22692423

DOI: 10.1126/scisignal.2002790

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24448649

Title: The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris.

PubMed ID: 24448649

DOI: 10.1126/scisignal.2004754

PubMed ID: 29146937

Title: TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes.

PubMed ID: 29146937

DOI: 10.1038/s41467-017-01871-z

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 30733432

Title: Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency.

PubMed ID: 30733432

DOI: 10.1038/s41467-018-08020-0

PubMed ID: 31672913

Title: Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.

PubMed ID: 31672913

DOI: 10.1126/science.aax0364

PubMed ID: 36608670

Title: A central role for regulated protein stability in the control of TFE3 and MITF by nutrients.

PubMed ID: 36608670

DOI: 10.1016/j.molcel.2022.12.013

PubMed ID: 37079666

Title: Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1.

PubMed ID: 37079666

DOI: 10.1126/science.abj5559

PubMed ID: 30595499

Title: Lysosomal signaling licenses embryonic stem cell differentiation via inactivation of Tfe3.

PubMed ID: 30595499

DOI: 10.1016/j.stem.2018.11.021

PubMed ID: 31833172

Title: TFE3-associated neurodevelopmental disorder: A distinct recognizable syndrome.

PubMed ID: 31833172

DOI: 10.1002/ajmg.a.61437

PubMed ID: 32409512

Title: De novo mutations in the X-linked TFE3 gene cause intellectual disability with pigmentary mosaicism and storage disorder-like features.

PubMed ID: 32409512

DOI: 10.1136/jmedgenet-2019-106508

Sequence Information:

  • Length: 575
  • Mass: 61521
  • Checksum: EF1F11AB624C6BE1
  • Sequence:
    • MSHAAEPARD GVEASAEGPR AVFVLLEERR PADSAQLLSL NSLLPESGIV ADIELENVLD 
PDSFYELKSQ PLPLRSSLPI SLQATPATPA TLSASSSAGG SRTPAMSSSS SSRVLLRQQL 
MRAQAQEQER RERREQAAAA PFPSPAPASP AISVVGVSAG GHTLSRPPPA QVPREVLKVQ 
THLENPTRYH LQQARRQQVK QYLSTTLGPK LASQALTPPP GPASAQPLPA PEAAHTTGPT 
GSAPNSPMAL LTIGSSSEKE IDDVIDEIIS LESSYNDEML SYLPGGTTGL QLPSTLPVSG 
NLLDVYSSQG VATPAITVSN SCPAELPNIK REISETEAKA LLKERQKKDN HNLIERRRRF 
NINDRIKELG TLIPKSSDPE MRWNKGTILK ASVDYIRKLQ KEQQRSKDLE SRQRSLEQAN 
RSLQLRIQEL ELQAQIHGLP VPPTPGLLSL ATTSASDSLK PEQLDIEEEG RPGAATFHVG 
GGPAQNAPHQ QPPAPPSDAL LDLHFPSDHL GDLGDPFHLG LEDILMEEEE GVVGGLSGGA 
LSPLRAASDP LLSSVSPAVS KASSRRSSFS MEEES

Genular Protein ID: 1695422076

Symbol: B4DIA5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DIA5

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 6 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 470
  • Mass: 50630
  • Checksum: 751F63788383E415
  • Sequence:
    • MSSSSSSRVL LRQQLMRAQA QEQERRERRE QAAAAPFPSP APASPAISVV GVSAGGHTLS 
RPPPAQVPRE VLKVQTHLEN PTRYHLQQAR RQQVKQYLST TLGPKLASQA LTPPPGPASA 
QPLPAPEAAH TTGPTGSAPN SPMALLTIGS SSEKEIDDVI DEIISLESSY NDEMLSYLPG 
GTTGLQLPST LPVSGNLLDV YSSQGVATPA ITVSNSCPAE LPNIKREISE TEAKALLKER 
QKKDNHNLIE RRRRFNINDR IKELGTLIPK SSDPEMRWNK GTILKASVDY IRKLQKEQQR 
SKDLESRQRS LEQANRSLQL RIQELELQAQ IHGLPVPPTP GLLSLATTSA SDSLKPEQLD 
IEEEGRPGAA TFHVGGGPAQ NAPHQQPPAP PSDALLDLHF PSDHLGDLGD PFHLGLEDIL 
MEEEEGVVGG LSGGALSPLR AASDPLLSSV SPAVSKASSR RSSFSMEEES

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.