Details for: TFRC

Gene ID: 7037

Gene Type:  Protein-coding  - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.

Symbol: TFRC

Ensembl ID: ENSG00000072274

Description: transferrin receptor

Selected Context(s):  Overall

Cell Significance Landscape

Contexts:

Associated with

Significant Cells

Cell Significance Index (CSI) scores for the chosen context(s)

  • elicited macrophage CL0000861
    CSI 56.55
    rCSI 51.92%
    PRS 55.77
  • alveolar macrophage CL0000583
    CSI 32.72
    rCSI 53.9%
    PRS 53.57
  • placental villous trophoblast CL2000060
    CSI 31.69
    rCSI 48.97%
    PRS 45.74
  • cerebral cortex endothelial cell CL1001602
    CSI 27.63
    rCSI 47.79%
    PRS 38.73
  • intestinal crypt stem cell of small intestine CL0009017
    CSI 19.01
    rCSI 51.23%
    PRS 56.73
  • central memory CD4-positive, alpha-beta T cell CL0000904
    CSI 16.21
    rCSI 9.57%
    PRS 63.8
  • lung macrophage CL1001603
    CSI 14.66
    rCSI 32.75%
    PRS 54.69
  • transit amplifying cell of small intestine CL0009012
    CSI 13.48
    rCSI 59.16%
    PRS 66.37
  • erythroblast CL0000765
    CSI 12.58
    rCSI 33.39%
    PRS 61.23
  • goblet cell CL0000160
    CSI 12.24
    rCSI 11.56%
    PRS 48.76
  • respiratory hillock cell CL4030023
    CSI 12.08
    rCSI 21.55%
    PRS 63.08
  • fallopian tube secretory epithelial cell CL4030006
    CSI 11.41
    rCSI 10.98%
    PRS 48.37
  • stromal cell of ovary CL0002132
    CSI 10.68
    rCSI 29.36%
    PRS 63.41
  • enterocyte of epithelium of large intestine CL0002071
    CSI 10.44
    rCSI 54.84%
    PRS 61.87
  • alternatively activated macrophage CL0000890
    CSI 10.28
    rCSI 12.92%
    PRS 61.48
  • lung interstitial macrophage CL4033043
    CSI 9.46
    rCSI 21.24%
    PRS 67.53
  • pancreatic ductal cell CL0002079
    CSI 9.21
    rCSI 17.91%
    PRS 50.15
  • transit amplifying cell of colon CL0009011
    CSI 9.09
    rCSI 10.67%
    PRS 51.35
  • intermediate monocyte CL0002393
    CSI 8.59
    rCSI 12.97%
    PRS 50.34
  • retinal ganglion cell CL0000740
    CSI 8.58
    rCSI 18.96%
    PRS 35.96
  • colon epithelial cell CL0011108
    CSI 8.32
    rCSI 8.71%
    PRS 45.01
  • glandular epithelial cell CL0000150
    CSI 7.94
    rCSI 20.91%
    PRS 70.13
  • macrophage CL0000235
    CSI 7.78
    rCSI 14.15%
    PRS 74.03
  • kidney interstitial alternatively activated macrophage CL1000695
    CSI 7.66
    rCSI 19.96%
    PRS 47.29
  • megakaryocyte-erythroid progenitor cell CL0000050
    CSI 7.16
    rCSI 6.46%
    PRS 44.65
  • syncytiotrophoblast cell CL0000525
    CSI 7.15
    rCSI 20.6%
    PRS 65.09
  • transit amplifying cell CL0009010
    CSI 6.48
    rCSI 9.92%
    PRS 63.85
  • kidney loop of Henle thin ascending limb epithelial cell CL1001107
    CSI 6.24
    rCSI 16.12%
    PRS 44.06
  • hematopoietic precursor cell CL0008001
    CSI 6.2
    rCSI 6.38%
    PRS 66.08
  • regular atrial cardiac myocyte CL0002129
    CSI 5.98
    rCSI 19.26%
    PRS 47.12
  • CD14-positive, CD16-positive monocyte CL0002397
    CSI 5.94
    rCSI 7.78%
    PRS 61.33
  • epithelial cell of lower respiratory tract CL0002632
    CSI 5.8
    rCSI 4.5%
    PRS 48.65
  • peripheral nervous system neuron CL2000032
    CSI 5.73
    rCSI 7.81%
    PRS 41.08
  • melanocyte CL0000148
    CSI 5.69
    rCSI 4.22%
    PRS 41.48
  • dendritic cell, human CL0001056
    CSI 5.53
    rCSI 8.49%
    PRS 55.33
  • primitive red blood cell CL0002355
    CSI 5.52
    rCSI 29.79%
    PRS 62.39
  • BEST4+ enteroycte CL4030026
    CSI 5.48
    rCSI 6.82%
    PRS 50.6
  • colon macrophage CL0009038
    CSI 5.45
    rCSI 25.18%
    PRS 69.93
  • respiratory suprabasal cell CL4033048
    CSI 5.33
    rCSI 6.83%
    PRS 52.76
  • keratinocyte CL0000312
    CSI 5.31
    rCSI 4.45%
    PRS 52.86
  • renal beta-intercalated cell CL0002201
    CSI 5.2
    rCSI 12.4%
    PRS 49.9
  • erythroid progenitor cell CL0000038
    CSI 5.18
    rCSI 29.67%
    PRS 58.66
  • erythrocyte CL0000232
    CSI 5.17
    rCSI 11.74%
    PRS 53.14
  • eosinophil CL0000771
    CSI 5.14
    rCSI 33.74%
    PRS 78.19
  • plasmacytoid dendritic cell, human CL0001058
    CSI 5.11
    rCSI 3.57%
    PRS 49.95
  • ciliated epithelial cell CL0000067
    CSI 5.04
    rCSI 4.43%
    PRS 37.04
  • epicardial adipocyte CL1000309
    CSI 4.97
    rCSI 16.19%
    PRS 49.93
  • mucosal invariant T cell CL0000940
    CSI 4.93
    rCSI 3.98%
    PRS 58.48
  • immature B cell CL0000816
    CSI 4.92
    rCSI 3.65%
    PRS 61.3
  • alpha-beta T cell CL0000789
    CSI 4.82
    rCSI 5.64%
    PRS 63.74
  • metallothionein-positive alveolar macrophage CL4033042
    CSI 4.74
    rCSI 51.52%
    PRS 76.34
  • multi-ciliated epithelial cell CL0005012
    CSI 4.63
    rCSI 4.62%
    PRS 42.1
  • Mueller cell CL0000636
    CSI 4.55
    rCSI 10.37%
    PRS 41.28
  • paneth cell of epithelium of small intestine CL1000343
    CSI 4.51
    rCSI 12.63%
    PRS 62.19
  • pancreatic D cell CL0000173
    CSI 4.38
    rCSI 4.31%
    PRS 50.58
  • Kupffer cell CL0000091
    CSI 4.21
    rCSI 9.62%
    PRS 47.4
  • activated CD8-positive, alpha-beta T cell, human CL0001049
    CSI 4.14
    rCSI 7.08%
    PRS 68.34
  • myeloid leukocyte CL0000766
    CSI 4.12
    rCSI 3.81%
    PRS 48.75
  • intestine goblet cell CL0019031
    CSI 4.1
    rCSI 3.64%
    PRS 46.85
  • periportal region hepatocyte CL0019026
    CSI 4.09
    rCSI 15.9%
    PRS 56.21
  • common myeloid progenitor CL0000049
    CSI 3.99
    rCSI 3.23%
    PRS 48.75
  • microcirculation associated smooth muscle cell CL0008035
    CSI 3.94
    rCSI 11.39%
    PRS 50.22
  • vascular associated smooth muscle cell CL0000359
    CSI 3.92
    rCSI 12.7%
    PRS 50.46
  • myofibroblast cell CL0000186
    CSI 3.87
    rCSI 5.36%
    PRS 52.3
  • lymphoid lineage restricted progenitor cell CL0000838
    CSI 3.62
    rCSI 14.1%
    PRS 68.57
  • pro-B cell CL0000826
    CSI 3.58
    rCSI 2.97%
    PRS 49.23
  • pulmonary capillary endothelial cell CL4028001
    CSI 3.58
    rCSI 6.83%
    PRS 64.93
  • stem cell CL0000034
    CSI 3.47
    rCSI 3.34%
    PRS 38.7
  • ON parasol ganglion cell CL4033052
    CSI 3.45
    rCSI 48.98%
    PRS 40.13
  • mature T cell CL0002419
    CSI 3.42
    rCSI 2.66%
    PRS 65.56
  • unswitched memory B cell CL0000970
    CSI 3.41
    rCSI 2.87%
    PRS 65.17
  • pvalb GABAergic cortical interneuron CL4023018
    CSI 3.36
    rCSI 4.18%
    PRS 30.31
  • CD4-positive, alpha-beta memory T cell CL0000897
    CSI 3.23
    rCSI 2.32%
    PRS 61.33
  • epithelial cell CL0000066
    CSI 3.21
    rCSI 4.93%
    PRS 48.76
  • hepatic stellate cell CL0000632
    CSI 3.19
    rCSI 11.96%
    PRS 40.93
  • sst GABAergic cortical interneuron CL4023017
    CSI 3.13
    rCSI 4.03%
    PRS 32.88
  • IgA plasma cell CL0000987
    CSI 3.11
    rCSI 3.19%
    PRS 65.74
  • early lymphoid progenitor CL0000936
    CSI 3.06
    rCSI 2.68%
    PRS 53.15
  • L5 extratelencephalic projecting glutamatergic cortical neuron CL4023041
    CSI 3.04
    rCSI 10.93%
    PRS 30.77
  • neural crest cell CL0011012
    CSI 3.04
    rCSI 2.4%
    PRS 35.68
  • ON midget ganglion cell CL4033046
    CSI 3.01
    rCSI 61.36%
    PRS 40.29
  • chandelier pvalb GABAergic cortical interneuron CL4023036
    CSI 3
    rCSI 9.39%
    PRS 35.58
  • vascular leptomeningeal cell CL4023051
    CSI 2.99
    rCSI 5.24%
    PRS 40.38
  • inflammatory macrophage CL0000863
    CSI 2.94
    rCSI 5.03%
    PRS 74.18
  • monocyte CL0000576
    CSI 2.94
    rCSI 5.31%
    PRS 68.33
  • OFF midget ganglion cell CL4033047
    CSI 2.94
    rCSI 59.79%
    PRS 41.53
  • regular ventricular cardiac myocyte CL0002131
    CSI 2.93
    rCSI 18.27%
    PRS 40.44
  • midzonal region hepatocyte CL0019028
    CSI 2.91
    rCSI 6.83%
    PRS 56.09
  • interneuron CL0000099
    CSI 2.82
    rCSI 5.66%
    PRS 37.79
  • pulmonary ionocyte CL0017000
    CSI 2.81
    rCSI 3.42%
    PRS 55.73
  • conjunctival epithelial cell CL1000432
    CSI 2.76
    rCSI 4.22%
    PRS 48.57
  • astrocyte of the cerebral cortex CL0002605
    CSI 2.75
    rCSI 6.16%
    PRS 32.7
  • CD14-positive monocyte CL0001054
    CSI 2.7
    rCSI 3.36%
    PRS 59.33
  • precursor B cell CL0000817
    CSI 2.69
    rCSI 2.36%
    PRS 57.89
  • T-helper 17 cell CL0000899
    CSI 2.69
    rCSI 2.13%
    PRS 70.11
  • endothelial cell of vascular tree CL0002139
    CSI 2.67
    rCSI 14.61%
    PRS 49.87
  • group 3 innate lymphoid cell CL0001071
    CSI 2.62
    rCSI 1.96%
    PRS 51.76
  • Langerhans cell CL0000453
    CSI 2.59
    rCSI 3.95%
    PRS 65.04
  • kidney distal convoluted tubule epithelial cell CL1000849
    CSI 2.56
    rCSI 27.09%
    PRS 48.43
  • intestinal crypt stem cell of colon CL0009043
    CSI 2.52
    rCSI 18.95%
    PRS 67.5
  • megakaryocyte CL0000556
    CSI 0.2
    rCSI 0.9%
    PRS 63.2%
  • central nervous system neuron CL2000029
    CSI 0.2
    rCSI 1.8%
    PRS 35.9%
  • direct pathway medium spiny neuron CL4023026
    CSI 0.3
    rCSI 6.3%
    PRS 31.4%
  • indirect pathway medium spiny neuron CL4023029
    CSI 0.3
    rCSI 7.2%
    PRS 32.3%
  • respiratory goblet cell CL0002370
    CSI 0.5
    rCSI 4.9%
    PRS 67.4%
  • L6b glutamatergic cortical neuron CL4023038
    CSI 0.5
    rCSI 1.7%
    PRS 33.2%
  • bronchial goblet cell CL1000312
    CSI 0.6
    rCSI 2.2%
    PRS 68.4%
  • deuterosomal cell CL4033044
    CSI 0.6
    rCSI 1.9%
    PRS 56.7%
  • myelocyte CL0002193
    CSI 0.6
    rCSI 4.1%
    PRS 79.5%
  • type L enteroendocrine cell CL0002279
    CSI 0.6
    rCSI 1.2%
    PRS 66.9%
  • type EC enteroendocrine cell CL0000577
    CSI 0.7
    rCSI 2.4%
    PRS 60.1%
  • megakaryocyte progenitor cell CL0000553
    CSI 0.7
    rCSI 12.3%
    PRS 81.0%
  • type B pancreatic cell CL0000169
    CSI 0.7
    rCSI 1.5%
    PRS 45.5%
  • neural progenitor cell CL0011020
    CSI 0.7
    rCSI 3.1%
    PRS 41.1%
  • amacrine cell CL0000561
    CSI 0.7
    rCSI 2.1%
    PRS 39.2%
  • memory T cell CL0000813
    CSI 0.7
    rCSI 1.4%
    PRS 77.3%
  • lung resident memory CD4-positive, alpha-beta T cell CL4033038
    CSI 0.7
    rCSI 7.3%
    PRS 84.6%
  • kidney connecting tubule epithelial cell CL1000768
    CSI 0.8
    rCSI 2.0%
    PRS 38.3%
  • retinal bipolar neuron CL0000748
    CSI 0.9
    rCSI 1.6%
    PRS 37.6%
  • colon goblet cell CL0009039
    CSI 0.9
    rCSI 2.2%
    PRS 59.8%
  • helper T cell CL0000912
    CSI 0.9
    rCSI 1.3%
    PRS 56.0%
  • retina horizontal cell CL0000745
    CSI 1.0
    rCSI 1.5%
    PRS 44.6%
  • stromal cell CL0000499
    CSI 1.0
    rCSI 2.7%
    PRS 47.3%
  • myeloid dendritic cell CL0000782
    CSI 1.0
    rCSI 1.4%
    PRS 64.4%
  • sncg GABAergic cortical interneuron CL4023015
    CSI 1.0
    rCSI 1.6%
    PRS 34.1%
  • L2/3-6 intratelencephalic projecting glutamatergic neuron CL4023040
    CSI 1.1
    rCSI 2.6%
    PRS 31.0%
  • caudal ganglionic eminence derived cortical interneuron CL4023064
    CSI 1.1
    rCSI 2.0%
    PRS 30.9%
  • lamp5 GABAergic cortical interneuron CL4023011
    CSI 1.1
    rCSI 1.9%
    PRS 31.9%
  • pancreatic acinar cell CL0002064
    CSI 1.2
    rCSI 1.6%
    PRS 53.1%
  • retinal blood vessel endothelial cell CL0002585
    CSI 1.2
    rCSI 1.9%
    PRS 52.1%
  • squamous epithelial cell CL0000076
    CSI 1.2
    rCSI 2.9%
    PRS 53.5%
  • brush cell CL0002204
    CSI 1.2
    rCSI 2.5%
    PRS 71.7%
  • intestinal tuft cell CL0019032
    CSI 1.3
    rCSI 2.0%
    PRS 52.8%
  • paneth cell CL0000510
    CSI 1.3
    rCSI 1.9%
    PRS 65.5%
  • OFF-bipolar cell CL0000750
    CSI 1.3
    rCSI 1.8%
    PRS 57.4%
  • pancreatic stellate cell CL0002410
    CSI 1.3
    rCSI 7.7%
    PRS 58.6%
  • mucous neck cell CL0000651
    CSI 1.3
    rCSI 1.9%
    PRS 61.3%
  • granulocyte CL0000094
    CSI 1.3
    rCSI 2.1%
    PRS 57.2%
  • centrilobular region hepatocyte CL0019029
    CSI 1.4
    rCSI 3.6%
    PRS 55.6%
  • common lymphoid progenitor CL0000051
    CSI 1.4
    rCSI 1.8%
    PRS 70.6%
  • small intestine goblet cell CL1000495
    CSI 1.4
    rCSI 3.0%
    PRS 57.7%
  • foveolar cell of stomach CL0002179
    CSI 1.4
    rCSI 3.0%
    PRS 62.5%
  • hepatocyte CL0000182
    CSI 1.4
    rCSI 2.6%
    PRS 46.5%
  • colonocyte CL1000347
    CSI 1.5
    rCSI 2.1%
    PRS 54.5%
  • extravillous trophoblast CL0008036
    CSI 1.5
    rCSI 1.8%
    PRS 43.8%
  • basophil mast progenitor cell CL0002028
    CSI 1.5
    rCSI 7.9%
    PRS 83.5%
  • enterocyte CL0000584
    CSI 1.5
    rCSI 2.5%
    PRS 55.7%
  • enteroendocrine cell of small intestine CL0009006
    CSI 1.5
    rCSI 3.4%
    PRS 62.8%
  • glial cell CL0000125
    CSI 1.5
    rCSI 5.9%
    PRS 41.0%
  • kidney loop of Henle thin descending limb epithelial cell CL1001111
    CSI 1.6
    rCSI 2.2%
    PRS 44.8%
  • myeloid lineage restricted progenitor cell CL0000839
    CSI 1.6
    rCSI 8.2%
    PRS 71.7%
  • granulocyte monocyte progenitor cell CL0000557
    CSI 1.6
    rCSI 1.4%
    PRS 52.0%
  • retinal pigment epithelial cell CL0002586
    CSI 1.6
    rCSI 3.2%
    PRS 47.0%
  • lung endothelial cell CL1001567
    CSI 1.6
    rCSI 3.8%
    PRS 71.9%
  • Hofbauer cell CL3000001
    CSI 1.6
    rCSI 3.1%
    PRS 58.5%
  • M cell of gut CL0000682
    CSI 1.7
    rCSI 1.8%
    PRS 62.2%
  • ionocyte CL0005006
    CSI 1.7
    rCSI 1.8%
    PRS 46.1%
  • VIP GABAergic cortical interneuron CL4023016
    CSI 1.7
    rCSI 2.0%
    PRS 31.8%
  • bronchus fibroblast of lung CL2000093
    CSI 1.7
    rCSI 1.4%
    PRS 48.6%
  • retinal cone cell CL0000573
    CSI 1.7
    rCSI 2.7%
    PRS 38.6%
  • effector CD4-positive, alpha-beta T cell CL0001044
    CSI 1.7
    rCSI 4.9%
    PRS 66.2%
  • CD14-low, CD16-positive monocyte CL0002396
    CSI 1.7
    rCSI 1.3%
    PRS 47.0%
  • intestinal epithelial cell CL0002563
    CSI 1.8
    rCSI 1.9%
    PRS 47.2%
  • promonocyte CL0000559
    CSI 1.8
    rCSI 3.1%
    PRS 57.4%
  • ON-bipolar cell CL0000749
    CSI 1.8
    rCSI 2.7%
    PRS 50.2%
  • lung ciliated cell CL1000271
    CSI 1.9
    rCSI 2.1%
    PRS 38.2%
  • respiratory basal cell CL0002633
    CSI 1.9
    rCSI 2.0%
    PRS 53.9%
  • corneal epithelial cell CL0000575
    CSI 1.9
    rCSI 5.4%
    PRS 64.2%
  • chondrocyte CL0000138
    CSI 1.9
    rCSI 3.0%
    PRS 40.9%
  • central memory CD8-positive, alpha-beta T cell CL0000907
    CSI 1.9
    rCSI 1.3%
    PRS 59.0%
  • basal cell of prostate epithelium CL0002341
    CSI 2.0
    rCSI 5.7%
    PRS 64.9%
  • near-projecting glutamatergic cortical neuron CL4023012
    CSI 2.0
    rCSI 7.6%
    PRS 32.9%
  • epithelial cell of lung CL0000082
    CSI 2.0
    rCSI 1.7%
    PRS 46.6%
  • choroid plexus epithelial cell CL0000706
    CSI 2.1
    rCSI 3.4%
    PRS 38.5%
  • hematopoietic multipotent progenitor cell CL0000837
    CSI 2.1
    rCSI 4.9%
    PRS 66.4%
  • CD1c-positive myeloid dendritic cell CL0002399
    CSI 2.1
    rCSI 2.6%
    PRS 56.0%
  • basal cell CL0000646
    CSI 2.1
    rCSI 2.9%
    PRS 49.3%
  • erythroid lineage cell CL0000764
    CSI 2.2
    rCSI 13.8%
    PRS 69.0%
  • rod bipolar cell CL0000751
    CSI 2.2
    rCSI 3.9%
    PRS 41.4%
  • fibroblast of lung CL0002553
    CSI 2.2
    rCSI 2.0%
    PRS 47.7%
  • perivascular cell CL4033054
    CSI 2.2
    rCSI 3.0%
    PRS 53.1%
  • lung secretory cell CL1000272
    CSI 2.2
    rCSI 5.5%
    PRS 45.9%
  • cerebellar granule cell CL0001031
    CSI 2.3
    rCSI 3.3%
    PRS 43.3%
  • enterocyte of epithelium of small intestine CL1000334
    CSI 2.3
    rCSI 35.4%
    PRS 72.1%
  • mononuclear phagocyte CL0000113
    CSI 2.3
    rCSI 5.0%
    PRS 52.1%
  • corticothalamic-projecting glutamatergic cortical neuron CL4023013
    CSI 2.3
    rCSI 13.8%
    PRS 33.3%
  • promyelocyte CL0000836
    CSI 2.4
    rCSI 3.4%
    PRS 57.9%
  • pancreatic A cell CL0000171
    CSI 2.4
    rCSI 2.5%
    PRS 51.1%
  • enteroendocrine cell CL0000164
    CSI 2.4
    rCSI 3.3%
    PRS 50.5%
  • secretory cell CL0000151
    CSI 2.4
    rCSI 2.5%
    PRS 48.5%
  • renal alpha-intercalated cell CL0005011
    CSI 2.4
    rCSI 3.3%
    PRS 56.6%
  • mature B cell CL0000785
    CSI 2.5
    rCSI 2.1%
    PRS 57.7%
  • tuft cell of colon CL0009041
    CSI 2.5
    rCSI 5.8%
    PRS 65.0%
  • CD4-positive helper T cell CL0000492
    CSI 2.5
    rCSI 1.9%
    PRS 60.8%
  • intestinal crypt stem cell of colon CL0009043
    CSI 2.5
    rCSI 19.0%
    PRS 67.5%
  • kidney distal convoluted tubule epithelial cell CL1000849
    CSI 2.6
    rCSI 27.1%
    PRS 48.4%
  • Langerhans cell CL0000453
    CSI 2.6
    rCSI 4.0%
    PRS 65.0%
  • group 3 innate lymphoid cell CL0001071
    CSI 2.6
    rCSI 2.0%
    PRS 51.8%
  • endothelial cell of vascular tree CL0002139
    CSI 2.7
    rCSI 14.6%
    PRS 49.9%
  • T-helper 17 cell CL0000899
    CSI 2.7
    rCSI 2.1%
    PRS 70.1%

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration

Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.

Comma-separated if multiple.
Comma-separated if multiple.

Legend:
  • Query Gene
  • Node Color (Target Cell CSI, relative to current network):
    • Very High
    • High
    • Medium
    • Low
    • Very Low
    • CSI N/A
  • Node Size: Proportional to Target Cell CSI magnitude
  • STRING PPI Edge
  • Shared Pathway Edge (ONTOLOGY)

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Other Information

This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.

## Summary [TFRC](/details-gene/7037), also known as Transferrin Receptor Protein 1, is a protein-coding gene located on chromosome 3q29. It encodes a cell surface receptor that is fundamental for cellular iron uptake via receptor-mediated endocytosis of iron-loaded transferrin ([Link](https://pubmed.ncbi.nlm.nih.gov/6090955/)). This process is critical for numerous physiological functions, particularly cell growth, proliferation, and metabolism. **Overall**, [TFRC](/details-gene/7037) shows the highest significance in cell types with high metabolic and proliferative demands, such as [elicited macrophage](/details-cell/CL0000861)s and [alveolar macrophage](/details-cell/CL0000583)s, as well as in highly active tissues like the placenta ([placental villous trophoblast](/details-cell/CL2000060)) and the brain endothelium ([cerebral cortex endothelial cell](/details-cell/CL1001602)). Its association with human health is noted in its OMIM entry ([190010](https://omim.org/entry/190010)). ## Cellular Roles and Expression Landscape The expression profile of [TFRC](/details-gene/7037) highlights its central role in iron homeostasis across a range of specialized cell types. Its significance is most pronounced in cells of the myeloid lineage, with [elicited macrophage](/details-cell/CL0000861) (CSI: 56.55) and [alveolar macrophage](/details-cell/CL0000583) (CSI: 32.72) being the top contexts. This suggests a critical function in iron recycling and inflammatory responses mediated by these phagocytes. Beyond the immune system, [TFRC](/details-gene/7037) is a key marker for highly proliferative epithelial tissues. It is significantly expressed in [intestinal crypt stem cell of small intestine](/details-cell/CL0009017) (CSI: 19.01) and [transit amplifying cell of small intestine](/details-cell/CL0009012) (CSI: 13.48), consistent with the high iron requirement for rapid cell division and tissue renewal in the gut. Similarly, its high significance in [erythroblast](/details-cell/CL0000765)s (CSI: 12.58) directly reflects the intense demand for iron during hemoglobin synthesis and erythropoiesis. Furthermore, [TFRC](/details-gene/7037) plays a role in specialized barrier and transport tissues. Its high expression in [placental villous trophoblast](/details-cell/CL2000060) (CSI: 31.69) underscores its importance in maternal-fetal iron transfer. The high CSI value in [cerebral cortex endothelial cell](/details-cell/CL1001602) (CSI: 27.63) is consistent with its function in transporting iron across the blood-brain barrier. The gene's expression in lymphoid cells, such as [central memory CD4-positive, alpha-beta T cell](/details-cell/CL0000904), aligns with its role in supporting the metabolic demands of lymphocyte activation and proliferation. ## Pathways and Molecular Function Functionally, [TFRC](/details-gene/7037) is principally involved in metal ion transport and cellular metabolism. Gene Ontology annotations confirm its molecular function as '[Transferrin receptor activity](/details-go/GO:0004998)' and its central biological process as '[Iron ion transport](/details-go/GO:0006826)' and '[Intracellular iron ion homeostasis](/details-go/GO:0006879)'. The primary mechanism of action is detailed in Reactome pathways such as '[Iron uptake and transport](/details-pathway/R-HSA-917937)' and '[Transferrin endocytosis and recycling](/details-pathway/R-HSA-917977)', which occur via '[Clathrin-mediated endocytosis](/details-pathway/R-HSA-8856828)'. Consistent with its expression in immune cells, [TFRC](/details-gene/7037) is linked to processes like '[Positive regulation of t cell proliferation](/details-go/GO:0042102)' and '[Positive regulation of b cell proliferation](/details-go/GO:0030890)', highlighting that iron availability is a rate-limiting factor for adaptive immune responses. The gene is also annotated in '[Response to hypoxia](/details-go/GO:0001666)', as its expression is known to be upregulated by hypoxia-inducible factors to increase cellular iron supply under low-oxygen conditions. Cellular component annotations place the protein at the '[Cell surface](/details-go/GO:0009986)', '[Plasma membrane](/details-go/GO:0005886)', and within endocytic machinery like '[Clathrin-coated pit](/details-go/GO:0005905)s' and '[Recycling endosome](/details-go/GO:0055037)s', reflecting its dynamic trafficking during iron uptake. ## Research Directions The high expression of [TFRC](/details-gene/7037) on rapidly dividing cells and specialized barrier tissues presents several compelling avenues for future research and therapeutic development. Its role as a gatekeeper for cellular iron makes it a critical node in both normal physiology and pathology, particularly in cancer and neurobiology. Based on the available data, two testable hypotheses are: 1. **Hypothesis 1:** Given its high expression in [cerebral cortex endothelial cell](/details-cell/CL1001602)s and its annotated role in '[Transport across blood-brain barrier](/details-go/GO:0150104)', the [TFRC](/details-gene/7037) receptor could be exploited as a "Trojan horse" to deliver therapeutic agents into the central nervous system. 2. **Hypothesis 2:** The high significance of [TFRC](/details-gene/7037) in highly proliferative cells like [intestinal crypt stem cell of small intestine](/details-cell/CL0009017) suggests that colorectal cancers originating from this compartment may exhibit a strong dependency on [TFRC](/details-gene/7037)-mediated iron uptake for survival and growth, making it a key metabolic vulnerability. A proposed experimental approach to test Hypothesis 2 would involve the use of patient-derived colorectal cancer organoids. In this system, one could utilize CRISPR-Cas9 to knock out [TFRC](/details-gene/7037) and subsequently assess the impact on organoid viability, growth rate, and cell cycle progression through 3D imaging and flow cytometry. Comparing these effects under varying levels of extracellular iron availability would further clarify the specific dependency on receptor-mediated uptake versus other iron sources. **Therapeutic Potential:** [TFRC](/details-gene/7037) represents a highly attractive therapeutic target, primarily for cancer. Because it is a cell surface protein that is significantly upregulated on many types of malignant cells to meet their high demand for iron, it is a prime candidate for targeted therapies. The therapeutic strategy would focus on **inhibition** or exploitation. It is an ideal target for antibody-drug conjugates (ADCs) that bind to [TFRC](/details-gene/7037) and deliver a cytotoxic payload specifically to cancer cells, or for monoclonal antibodies that block transferrin binding, thereby starving the cells of iron. Its expression on key immune cells also suggests that targeting [TFRC](/details-gene/7037) could modulate immune responses, although this requires further investigation.

Genular Protein ID: 3134889831

Symbol: TFR1_HUMAN

Name: Transferrin receptor protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 6090955

Title: Primary structure of human transferrin receptor deduced from the mRNA sequence.

PubMed ID: 6090955

DOI: 10.1038/311675b0

PubMed ID: 6094009

Title: The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence.

PubMed ID: 6094009

DOI: 10.1016/0092-8674(84)90004-7

PubMed ID: 9358047

Title: Exon/intron structure of the human transferrin receptor gene.

PubMed ID: 9358047

DOI: 10.1016/s0378-1119(97)00356-9

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2229063

Title: Serum transferrin receptor is a truncated form of tissue receptor.

PubMed ID: 2229063

DOI: 10.1016/s0021-9258(17)30627-0

PubMed ID: 1871153

Title: Characterization of transferrin receptor released by K562 erythroleukemia cells.

PubMed ID: 1871153

DOI: 10.3181/00379727-197-43276

PubMed ID: 7864799

Title: Identification of a novel form of the alpha 3 integrin subunit: covalent association with transferrin receptor.

PubMed ID: 7864799

DOI: 10.1042/bj3060129

PubMed ID: 1380674

Title: Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size.

PubMed ID: 1380674

DOI: 10.1038/358764a0

PubMed ID: 3568132

Title: Endocytosis of the transferrin receptor requires the cytoplasmic domain but not its phosphorylation site.

PubMed ID: 3568132

DOI: 10.1016/0092-8674(87)90295-9

PubMed ID: 3582362

Title: Identification of the intermolecular disulfide bonds of the human transferrin receptor and its lipid-attachment site.

PubMed ID: 3582362

DOI: 10.1002/j.1460-2075.1987.tb04758.x

PubMed ID: 2507316

Title: Intermolecular disulfide bonds are not required for the expression of the dimeric state and functional activity of the transferrin receptor.

PubMed ID: 2507316

DOI: 10.1002/j.1460-2075.1989.tb08347.x

PubMed ID: 2327986

Title: A point mutation in the cytoplasmic domain of the transferrin receptor inhibits endocytosis.

PubMed ID: 2327986

DOI: 10.1042/bj2670031

PubMed ID: 2298808

Title: Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization.

PubMed ID: 2298808

DOI: 10.1083/jcb.110.2.283

PubMed ID: 1421756

Title: Presence of O-linked oligosaccharide on a threonine residue in the human transferrin receptor.

PubMed ID: 1421756

DOI: 10.1093/glycob/2.4.345

PubMed ID: 1421757

Title: Identification of the O-linked glycosylation site of the human transferrin receptor.

PubMed ID: 1421757

DOI: 10.1093/glycob/2.4.355

PubMed ID: 8408022

Title: YTRF is the conserved internalization signal of the transferrin receptor, and a second YTRF signal at position 31-34 enhances endocytosis.

PubMed ID: 8408022

DOI: 10.1016/s0021-9258(20)80596-1

PubMed ID: 7780197

Title: The critical glycosylation site of human transferrin receptor contains a high-mannose oligosaccharide.

PubMed ID: 7780197

DOI: 10.1093/glycob/5.2.227

PubMed ID: 8631371

Title: Functional analysis of human/chicken transferrin receptor chimeras indicates that the carboxy-terminal region is important for ligand binding.

PubMed ID: 8631371

DOI: 10.1111/j.1432-1033.1996.0009u.x

PubMed ID: 10377239

Title: A conserved RGD (Arg-Gly-Asp) motif in the transferrin receptor is required for binding to transferrin.

PubMed ID: 10377239

DOI: 10.1042/bj3410011

PubMed ID: 11800564

Title: Mutational analysis of the transferrin receptor reveals overlapping HFE and transferrin binding sites.

PubMed ID: 11800564

DOI: 10.1006/jmbi.2001.5048

PubMed ID: 16325581

Title: TTP specifically regulates the internalization of the transferrin receptor.

PubMed ID: 16325581

DOI: 10.1016/j.cell.2005.10.021

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17081065

Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

PubMed ID: 17081065

DOI: 10.1021/pr060363j

PubMed ID: 17287727

Title: Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses.

PubMed ID: 17287727

DOI: 10.1038/nature05539

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18268337

Title: Receptor determinants of zoonotic transmission of New World hemorrhagic fever arenaviruses.

PubMed ID: 18268337

DOI: 10.1073/pnas.0709254105

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26214738

Title: Regulation of mitochondrial morphology and function by stearoylation of TFR1.

PubMed ID: 26214738

DOI: 10.1038/nature14601

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 9782058

Title: Structural model of phospholipid-reconstituted human transferrin receptor derived by electron microscopy.

PubMed ID: 9782058

DOI: 10.1016/s0969-2126(98)00124-5

PubMed ID: 10531064

Title: Crystal structure of the ectodomain of human transferrin receptor.

PubMed ID: 10531064

DOI: 10.1126/science.286.5440.779

PubMed ID: 11702220

Title: Identification of 96 single nucleotide polymorphisms in eight genes involved in iron metabolism: efficiency of bioinformatic extraction compared with a systematic sequencing approach.

PubMed ID: 11702220

DOI: 10.1007/s004390100599

PubMed ID: 26642240

Title: A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.

PubMed ID: 26642240

DOI: 10.1038/ng.3465

Sequence Information:

  • Length: 760
  • Mass: 84871
  • Checksum: C886F14000D90154
  • Sequence:
  • MMDQARSAFS NLFGGEPLSY TRFSLARQVD GDNSHVEMKL AVDEEENADN NTKANVTKPK 
    RCSGSICYGT IAVIVFFLIG FMIGYLGYCK GVEPKTECER LAGTESPVRE EPGEDFPAAR 
    RLYWDDLKRK LSEKLDSTDF TGTIKLLNEN SYVPREAGSQ KDENLALYVE NQFREFKLSK 
    VWRDQHFVKI QVKDSAQNSV IIVDKNGRLV YLVENPGGYV AYSKAATVTG KLVHANFGTK 
    KDFEDLYTPV NGSIVIVRAG KITFAEKVAN AESLNAIGVL IYMDQTKFPI VNAELSFFGH 
    AHLGTGDPYT PGFPSFNHTQ FPPSRSSGLP NIPVQTISRA AAEKLFGNME GDCPSDWKTD 
    STCRMVTSES KNVKLTVSNV LKEIKILNIF GVIKGFVEPD HYVVVGAQRD AWGPGAAKSG 
    VGTALLLKLA QMFSDMVLKD GFQPSRSIIF ASWSAGDFGS VGATEWLEGY LSSLHLKAFT 
    YINLDKAVLG TSNFKVSASP LLYTLIEKTM QNVKHPVTGQ FLYQDSNWAS KVEKLTLDNA 
    AFPFLAYSGI PAVSFCFCED TDYPYLGTTM DTYKELIERI PELNKVARAA AEVAGQFVIK 
    LTHDVELNLD YERYNSQLLS FVRDLNQYRA DIKEMGLSLQ WLYSARGDFF RATSRLTTDF 
    GNAEKTDRFV MKKLNDRVMR VEYHFLSPYV SPKESPFRHV FWGSGSHTLP ALLENLKLRK 
    QNNGAFNETL FRNQLALATW TIQGAANALS GDVWDIDNEF

Genular Protein ID: 937746282

Symbol: A0A8V8TM46_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 478
  • Mass: 53436
  • Checksum: 223C6210920B6596
  • Sequence:
  • MDQTKFPIVN AELSFFGHAH LGTGDPYTPG FPSFNHTQFP PSRSSGLPNI PVQTISRAAA 
    EKLFGNMEGD CPSDWKTDST CRMVTSESKN VKLTVSNVLK EIKILNIFGV IKGFVEPDHY 
    VVVGAQRDAW GPGAAKSGVG TALLLKLAQM FSDMVLKDGF QPSRSIIFAS WSAGDFGSVG 
    ATEWLEGYLS SLHLKAFTYI NLDKAVLGTS NFKVSASPLL YTLIEKTMQN VKHPVTGQFL 
    YQDSNWASKV EKLTLDNAAF PFLAYSGIPA VSFCFCEDTD YPYLGTTMDT YKELIERIPE 
    LNKVARAAAE VAGQFVIKLT HDVELNLDYE RYNSQLLSFV RDLNQYRADI KEMGLSLQWL 
    YSARGDFFRA TSRLTTDFGN AEKTDRFVMK KLNDRVMRVE YHFLSPYVSP KESPFRHVFW 
    GSGSHTLPAL LENLKLRKQN NGAFNETLFR NQLALATWTI QGAANALSGD VWDIDNEF

Genular Protein ID: 1748059015

Symbol: A8K6Q8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 760
  • Mass: 84873
  • Checksum: 3DAEE97671E394D4
  • Sequence:
  • MMDQARSAFS NLFGGEPLSY TRFSLARQVD GDNSHVEMKL AVDEEENADN NTKANVTKPK 
    RCSGSICYGT IAVIVFFLIG FMIGYLGYCK GVEPKTECER LAGTESPVRE EPGEDFPAAR 
    RLYWDDLKRK LSEKLDSTDF TSTIKLLNEN SYVPREAGSQ KDENLALYVE NQFREFKLSK 
    VWRDQHFVKI QVKDSAQNSV IIVDKNGRLV YLVENPGGYV AYSKAATATG KLVHANFGTK 
    KDFEDLYTPV NGSIVIVRAG KITFAEKVAN AESLNAIGVL IYMDQTKFPI VNAELSFFGH 
    AHLGTGDPYT PGFPSFNHTQ FPPSRSSGLP NIPVQTISRA AAEKLFGNME GDCPSDWKTD 
    STCRMVTSES KNVKLTVSNV LKEIKILNIF GVIKGFVEPD HYVVVGAQRD AWGPGAAKSG 
    VGTALLLKLA QMFSDMVLKD GFQPSRSIIF ASWSAGDFGS VGATEWLEGY LSSLHLKAFT 
    YINLDKAVLG TSNFKVSASP LLYTLIEKTM QNVKHPVTGQ FLYQDSNWAS KVEKLTLDNA 
    AFPFLAYSGI PAVSFCFCED TDYPYLGTTM DTYKELIERI PELNKVARAA AEVAGQFVIK 
    LTHDVELNLD YERYNSQLLS FVRDLNQYRA DIKEMGLSLQ WLYSARGDFF RATSRLTTDF 
    GNAEKTDRFV MKKLNDRVMR VEYHFLSPYV SPKESPFRHV FWGSGSHTLP ALLENLKLRK 
    QNNGAFNETL FRNQLALATW TIQGAANALS GDVWDIDNEF

Genular Protein ID: 662021783

Symbol: B7Z2I6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 478
  • Mass: 53484
  • Checksum: D23C6217E3CC79EB
  • Sequence:
  • MDQTKFPIVN AELSFFGHAH LGTGDPYTPG FPSFNHTQFP PSRSSGLPNI PVQTISRAAA 
    EKLFGNMEGD CPSDWKTDST CRMVTSESKN VKLTVSNVLK EIKILNIFGV IKGFVEPDHY 
    VVVGAQRDAW GPGAAKSGVG TALLLKLAQM FSDMVLKDGF QPSRSIIFAS WSAGDFGSVG 
    ATEWLEGYLS SLHLKAFTYI NLDKAVLGTS NFKVSASPLL YTLIEKTMQN VKHPFTGQFL 
    YQDSNWASKV EKLTLDNAAF PFLAYSGIPA VSFCFCEDTD YPYLGTTMDT YKELIERIPE 
    LNKVARAAAE VAGQFVIKLT HDVELNLDYE RYNSQLLSFV RDLNQYRADI KEMGLSLQWL 
    YSARGDFFRA TSRLTTDFGN AEKTDRFVMK KLNDRVMRVE YHFLSPYVSP KESPFRHVFW 
    GSGSHTLPAL LENLKLRKQN NGAFNETLFR NQLALATWTI QGAANALSGD VWDIDNEF

Genular Protein ID: 1454524531

Symbol: G3V0E5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 679
  • Mass: 75964
  • Checksum: 00830FDA9668C11B
  • Sequence:
  • MIGYLGYCKG VEPKTECERL AGTESPVREE PGEDFPAARR LYWDDLKRKL SEKLDSTDFT 
    GTIKLLNENS YVPREAGSQK DENLALYVEN QFREFKLSKV WRDQHFVKIQ VKDSAQNSVI 
    IVDKNGRLVY LVENPGGYVA YSKAATVTGK LVHANFGTKK DFEDLYTPVN GSIVIVRAGK 
    ITFAEKVANA ESLNAIGVLI YMDQTKFPIV NAELSFFGHA HLGTGDPYTP GFPSFNHTQF 
    PPSRSSGLPN IPVQTISRAA AEKLFGNMEG DCPSDWKTDS TCRMVTSESK NVKLTVSNVL 
    KEIKILNIFG VIKGFVEPDH YVVVGAQRDA WGPGAAKSGV GTALLLKLAQ MFSDMVLKDG 
    FQPSRSIIFA SWSAGDFGSV GATEWLEGYL SSLHLKAFTY INLDKAVLGT SNFKVSASPL 
    LYTLIEKTMQ NVKHPVTGQF LYQDSNWASK VEKLTLDNAA FPFLAYSGIP AVSFCFCEDT 
    DYPYLGTTMD TYKELIERIP ELNKVARAAA EVAGQFVIKL THDVELNLDY ERYNSQLLSF 
    VRDLNQYRAD IKEMGLSLQW LYSARGDFFR ATSRLTTDFG NAEKTDRFVM KKLNDRVMRV 
    EYHFLSPYVS PKESPFRHVF WGSGSHTLPA LLENLKLRKQ NNGAFNETLF RNQLALATWT 
    IQGAANALSG DVWDIDNEF

Genular Protein ID: 604985350

Symbol: Q7Z3E0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 13
  • Mass: 1468
  • Checksum: 8FE0E6255E80CDC5
  • Sequence:
  • MDQARSAFSN LDL