Details for: TLR5

Gene ID: 7100

Symbol: TLR5

Ensembl ID: ENSG00000187554

Description: toll like receptor 5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 52.7178
    Cell Significance Index: -8.2000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 32.3683
    Cell Significance Index: -8.2100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 17.7597
    Cell Significance Index: -7.2200
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 8.1230
    Cell Significance Index: 117.9400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 6.6507
    Cell Significance Index: -8.2000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.0125
    Cell Significance Index: -8.0700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.0806
    Cell Significance Index: -8.2100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0869
    Cell Significance Index: 206.8400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7713
    Cell Significance Index: 76.3000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.6721
    Cell Significance Index: 9.1700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6467
    Cell Significance Index: 583.9400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.5541
    Cell Significance Index: 11.8000
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.5384
    Cell Significance Index: 6.6600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3981
    Cell Significance Index: 64.7600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.3906
    Cell Significance Index: 7.2200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3722
    Cell Significance Index: 40.4800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3313
    Cell Significance Index: 17.2100
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.2487
    Cell Significance Index: 2.5700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2399
    Cell Significance Index: 14.4000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2162
    Cell Significance Index: 10.0800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2043
    Cell Significance Index: 14.1300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1492
    Cell Significance Index: 4.1700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1488
    Cell Significance Index: 53.3900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1019
    Cell Significance Index: 11.8700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0949
    Cell Significance Index: 51.8300
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.0945
    Cell Significance Index: 1.5000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0742
    Cell Significance Index: 32.8200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0686
    Cell Significance Index: 12.3600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0545
    Cell Significance Index: 2.5600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0526
    Cell Significance Index: 2.6600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0499
    Cell Significance Index: 1.0800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.0280
    Cell Significance Index: 0.2600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0268
    Cell Significance Index: 0.6700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0191
    Cell Significance Index: 0.5500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0159
    Cell Significance Index: 0.5600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0126
    Cell Significance Index: 1.5500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0093
    Cell Significance Index: 17.4400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0090
    Cell Significance Index: 0.2500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0089
    Cell Significance Index: 6.5200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0077
    Cell Significance Index: 0.3500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0012
    Cell Significance Index: 0.9000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0014
    Cell Significance Index: -2.6700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0029
    Cell Significance Index: -2.0200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0050
    Cell Significance Index: -7.7700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0074
    Cell Significance Index: -10.0000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0104
    Cell Significance Index: -2.0900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0105
    Cell Significance Index: -6.7000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0108
    Cell Significance Index: -1.4800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0113
    Cell Significance Index: -8.3800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0115
    Cell Significance Index: -3.3200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0130
    Cell Significance Index: -5.9200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0133
    Cell Significance Index: -2.6500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0135
    Cell Significance Index: -1.3800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0138
    Cell Significance Index: -7.8100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0143
    Cell Significance Index: -8.9000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0166
    Cell Significance Index: -2.1300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0189
    Cell Significance Index: -2.1700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0235
    Cell Significance Index: -3.0400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0267
    Cell Significance Index: -1.3900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0292
    Cell Significance Index: -0.5700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0345
    Cell Significance Index: -0.5200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0386
    Cell Significance Index: -6.5900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0438
    Cell Significance Index: -1.1700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0448
    Cell Significance Index: -9.4400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0466
    Cell Significance Index: -6.7700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0657
    Cell Significance Index: -4.9000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0691
    Cell Significance Index: -8.1500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0724
    Cell Significance Index: -4.4400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0774
    Cell Significance Index: -2.4800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0778
    Cell Significance Index: -8.1000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0795
    Cell Significance Index: -1.6500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0813
    Cell Significance Index: -2.1800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0843
    Cell Significance Index: -6.6800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0852
    Cell Significance Index: -2.2400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0889
    Cell Significance Index: -6.2900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0979
    Cell Significance Index: -7.5100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1040
    Cell Significance Index: -5.8400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1046
    Cell Significance Index: -7.0300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1105
    Cell Significance Index: -6.7900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1220
    Cell Significance Index: -7.8700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1385
    Cell Significance Index: -8.7300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1453
    Cell Significance Index: -7.6300
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1508
    Cell Significance Index: -1.2300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1519
    Cell Significance Index: -3.5100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1524
    Cell Significance Index: -6.7400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1576
    Cell Significance Index: -5.5200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1654
    Cell Significance Index: -6.0700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1735
    Cell Significance Index: -6.5700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1976
    Cell Significance Index: -2.8300
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.2031
    Cell Significance Index: -1.8300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2043
    Cell Significance Index: -6.6900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2047
    Cell Significance Index: -6.0300
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2111
    Cell Significance Index: -9.1800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2173
    Cell Significance Index: -7.5500
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.2176
    Cell Significance Index: -2.5300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2215
    Cell Significance Index: -6.3500
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.2227
    Cell Significance Index: -3.1700
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.2381
    Cell Significance Index: -4.6600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2389
    Cell Significance Index: -7.6100
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.2402
    Cell Significance Index: -6.0000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Recognition of bacterial flagellin**: TLR5 recognizes flagellin, a protein component of bacterial flagella, triggering a signaling cascade that leads to the activation of downstream immune response pathways. 2. **Mechanotransduction**: TLR5 is also capable of detecting mechanical stimuli, such as shear stress, and transducing signals into cellular responses. 3. **Cellular localization**: TLR5 is expressed on various cell types, including innate lymphoid cells, epithelial cells, and immune cells, highlighting its role in multiple tissues and cell types. 4. **Signal transduction**: TLR5 activates a signaling cascade involving MyD88, TRAF6, and NF-κB, leading to the production of pro-inflammatory cytokines and the activation of immune cells. **Pathways and Functions:** 1. **Innate immune response**: TLR5 plays a critical role in the recognition of bacterial pathogens and the activation of an innate immune response, including the production of pro-inflammatory cytokines and the activation of immune cells. 2. **Mechanotransduction**: TLR5 is involved in the detection of mechanical stimuli, such as shear stress, and transducing signals into cellular responses, including the regulation of cell growth and differentiation. 3. **Cell signaling**: TLR5 is a key player in cell signaling pathways, including the regulation of inflammatory responses, cell proliferation, and differentiation. 4. **Interleukin-8 production**: TLR5 activation leads to the production of interleukin-8 (IL-8), a pro-inflammatory cytokine involved in the recruitment of immune cells to sites of infection. **Clinical Significance:** 1. **Infectious diseases**: Dysregulation of TLR5 has been implicated in various infectious diseases, including tuberculosis, Salmonella infections, and bacterial meningitis. 2. **Autoimmune diseases**: TLR5 has been linked to autoimmune diseases, such as rheumatoid arthritis and lupus, where its dysregulation leads to an exaggerated immune response. 3. **Cancer**: TLR5 has been implicated in cancer progression, where its activation leads to the promotion of tumor growth and metastasis. 4. **Neurological disorders**: TLR5 has been linked to neurological disorders, such as multiple sclerosis and Alzheimer's disease, where its dysregulation leads to an exaggerated immune response and inflammation. In conclusion, TLR5 is a critical component of the innate immune system, playing a pivotal role in the recognition of bacterial pathogens and the regulation of inflammatory responses. Its dysregulation has been implicated in various diseases, highlighting the importance of TLR5 in maintaining immune homeostasis. Further research is needed to elucidate the mechanisms underlying TLR5 function and its role in disease.

Genular Protein ID: 2898685059

Symbol: TLR5_HUMAN

Name: Toll-like receptor 5

UniProtKB Accession Codes:

O60602 B1AZ05 B3Y633 B9VJ63 D1CS80 D3DTB8 O15456 Q32MI2 Q32MI3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEMBL 1 DNASU 1 DisGeNET 1 EMBL 18 EMDB 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 11 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 6 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIRSF 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 4 RefSeq 9 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9596645

Title: Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans.

PubMed ID: 9596645

PubMed ID: 18810425

Title: Natural selection in the TLR-related genes in the course of primate evolution.

PubMed ID: 18810425

DOI: 10.1007/s00251-008-0332-0

PubMed ID: 19179655

Title: A history of recurrent positive selection at the toll-like receptor 5 in primates.

PubMed ID: 19179655

DOI: 10.1093/molbev/msp018

PubMed ID: 19924287

Title: The heterogeneous allelic repertoire of human Toll-Like receptor (TLR) genes.

PubMed ID: 19924287

DOI: 10.1371/journal.pone.0007803

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9435236

Title: A family of human receptors structurally related to Drosophila Toll.

PubMed ID: 9435236

DOI: 10.1073/pnas.95.2.588

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 11489966

Title: Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression.

PubMed ID: 11489966

DOI: 10.4049/jimmunol.167.4.1882

PubMed ID: 11323673

Title: The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5.

PubMed ID: 11323673

DOI: 10.1038/35074106

PubMed ID: 16027372

Title: A stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus.

PubMed ID: 16027372

DOI: 10.1073/pnas.0501165102

PubMed ID: 17157808

Title: A phosphorylation site in the Toll-like receptor 5 TIR domain is required for inflammatory signalling in response to flagellin.

PubMed ID: 17157808

DOI: 10.1016/j.bbrc.2006.11.132

PubMed ID: 17442957

Title: Protein kinase D interaction with TLR5 is required for inflammatory signaling in response to bacterial flagellin.

PubMed ID: 17442957

DOI: 10.4049/jimmunol.178.9.5735

PubMed ID: 18490781

Title: Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease.

PubMed ID: 18490781

DOI: 10.4049/jimmunol.180.11.7764

PubMed ID: 20855887

Title: TRIF mediates Toll-like receptor 5-induced signaling in intestinal epithelial cells.

PubMed ID: 20855887

DOI: 10.1074/jbc.m110.158394

PubMed ID: 23447684

Title: Impaired TLR5 functionality is associated with survival in melioidosis.

PubMed ID: 23447684

DOI: 10.4049/jimmunol.1202974

PubMed ID: 24778236

Title: UNC93B1 is essential for the plasma membrane localization and signaling of Toll-like receptor 5.

PubMed ID: 24778236

DOI: 10.1073/pnas.1322838111

PubMed ID: 29934223

Title: Enterohemorrhagic Escherichia coli O157 outer membrane vesicles induce interleukin 8 production in human intestinal epithelial cells by signaling via Toll-like receptors TLR4 and TLR5 and activation of the nuclear factor NF-kappaB.

PubMed ID: 29934223

DOI: 10.1016/j.ijmm.2018.06.004

PubMed ID: 22173220

Title: Toll-like receptor 5 forms asymmetric dimers in the absence of flagellin.

PubMed ID: 22173220

DOI: 10.1016/j.jsb.2011.12.002

PubMed ID: 14623910

Title: A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease.

PubMed ID: 14623910

DOI: 10.1084/jem.20031220

Sequence Information:

  • Length: 858
  • Mass: 97800
  • Checksum: 9EE0AB6EE1E470B1
  • Sequence:
    • MGDHLDLLLG VVLMAGPVFG IPSCSFDGRI AFYRFCNLTQ VPQVLNTTER LLLSFNYIRT 
VTASSFPFLE QLQLLELGSQ YTPLTIDKEA FRNLPNLRIL DLGSSKIYFL HPDAFQGLFH 
LFELRLYFCG LSDAVLKDGY FRNLKALTRL DLSKNQIRSL YLHPSFGKLN SLKSIDFSSN 
QIFLVCEHEL EPLQGKTLSF FSLAANSLYS RVSVDWGKCM NPFRNMVLEI LDVSGNGWTV 
DITGNFSNAI SKSQAFSLIL AHHIMGAGFG FHNIKDPDQN TFAGLARSSV RHLDLSHGFV 
FSLNSRVFET LKDLKVLNLA YNKINKIADE AFYGLDNLQV LNLSYNLLGE LYSSNFYGLP 
KVAYIDLQKN HIAIIQDQTF KFLEKLQTLD LRDNALTTIH FIPSIPDIFL SGNKLVTLPK 
INLTANLIHL SENRLENLDI LYFLLRVPHL QILILNQNRF SSCSGDQTPS ENPSLEQLFL 
GENMLQLAWE TELCWDVFEG LSHLQVLYLN HNYLNSLPPG VFSHLTALRG LSLNSNRLTV 
LSHNDLPANL EILDISRNQL LAPNPDVFVS LSVLDITHNK FICECELSTF INWLNHTNVT 
IAGPPADIYC VYPDSFSGVS LFSLSTEGCD EEEVLKSLKF SLFIVCTVTL TLFLMTILTV 
TKFRGFCFIC YKTAQRLVFK DHPQGTEPDM YKYDAYLCFS SKDFTWVQNA LLKHLDTQYS 
DQNRFNLCFE ERDFVPGENR IANIQDAIWN SRKIVCLVSR HFLRDGWCLE AFSYAQGRCL 
SDLNSALIMV VVGSLSQYQL MKHQSIRGFV QKQQYLRWPE DLQDVGWFLH KLSQQILKKE 
KEKKKDNNIP LQTVATIS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.