Details for: UGT2B7

Gene ID: 7364

Symbol: UGT2B7

Ensembl ID: ENSG00000171234

Description: UDP glucuronosyltransferase family 2 member B7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 14.2022
    Cell Significance Index: -9.5300
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 6.9972
    Cell Significance Index: 174.4900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 4.7590
    Cell Significance Index: 109.9500
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 3.9238
    Cell Significance Index: 33.3500
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 3.3942
    Cell Significance Index: 31.5000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 3.0789
    Cell Significance Index: 585.9400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.8262
    Cell Significance Index: 195.4500
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 1.8082
    Cell Significance Index: 4.7700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.5307
    Cell Significance Index: -3.3500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.3421
    Cell Significance Index: 1211.8000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.3292
    Cell Significance Index: 79.8000
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.2149
    Cell Significance Index: 9.7000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.1083
    Cell Significance Index: 605.2900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.1000
    Cell Significance Index: 119.6500
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.0061
    Cell Significance Index: 24.3700
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.9200
    Cell Significance Index: 15.1600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8221
    Cell Significance Index: 133.7100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.8191
    Cell Significance Index: 12.0900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.8047
    Cell Significance Index: 23.1900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.7491
    Cell Significance Index: 11.5900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.6756
    Cell Significance Index: 11.3800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.6676
    Cell Significance Index: 10.0600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5638
    Cell Significance Index: 111.8900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5278
    Cell Significance Index: 52.2100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3766
    Cell Significance Index: 8.1600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: 0.2655
    Cell Significance Index: 21.0300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2294
    Cell Significance Index: 8.0600
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.2214
    Cell Significance Index: 1.2800
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.2148
    Cell Significance Index: 2.9800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.1789
    Cell Significance Index: 2.6800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1680
    Cell Significance Index: 30.2900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1264
    Cell Significance Index: 3.1600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0939
    Cell Significance Index: 1.5800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0819
    Cell Significance Index: 2.1100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0666
    Cell Significance Index: 11.3800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0571
    Cell Significance Index: 107.4300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0542
    Cell Significance Index: 0.7400
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 0.0534
    Cell Significance Index: 0.4500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0459
    Cell Significance Index: 6.3000
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.0452
    Cell Significance Index: 0.5200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0418
    Cell Significance Index: 0.8900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0382
    Cell Significance Index: 1.7300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0272
    Cell Significance Index: 3.3500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0137
    Cell Significance Index: 1.6000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0135
    Cell Significance Index: 9.8700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0013
    Cell Significance Index: 0.1800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0008
    Cell Significance Index: 0.0200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0002
    Cell Significance Index: -0.2600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0016
    Cell Significance Index: -2.9200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0032
    Cell Significance Index: -4.2900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0056
    Cell Significance Index: -0.6500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0057
    Cell Significance Index: -4.2800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0066
    Cell Significance Index: -0.6700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0128
    Cell Significance Index: -8.1300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0128
    Cell Significance Index: -9.4900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0151
    Cell Significance Index: -9.4600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0173
    Cell Significance Index: -9.7800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0174
    Cell Significance Index: -3.4900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0193
    Cell Significance Index: -0.2000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0244
    Cell Significance Index: -11.0800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0254
    Cell Significance Index: -9.1200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0289
    Cell Significance Index: -0.8500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0290
    Cell Significance Index: -8.3400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0364
    Cell Significance Index: -2.2300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0448
    Cell Significance Index: -2.0900
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0474
    Cell Significance Index: -0.3600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0530
    Cell Significance Index: -11.1600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0628
    Cell Significance Index: -3.2600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0706
    Cell Significance Index: -7.3500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0836
    Cell Significance Index: -10.8000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0895
    Cell Significance Index: -2.8700
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.0949
    Cell Significance Index: -1.3300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1329
    Cell Significance Index: -8.9400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1400
    Cell Significance Index: -5.1400
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.1487
    Cell Significance Index: -1.3400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1553
    Cell Significance Index: -11.5800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1568
    Cell Significance Index: -12.0300
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: -0.1659
    Cell Significance Index: -1.3200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1744
    Cell Significance Index: -10.7200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1765
    Cell Significance Index: -8.3000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1792
    Cell Significance Index: -3.7500
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: -0.1872
    Cell Significance Index: -1.4300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.1923
    Cell Significance Index: -1.3000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2083
    Cell Significance Index: -11.6900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2090
    Cell Significance Index: -4.0800
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2153
    Cell Significance Index: -6.8100
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: -0.2230
    Cell Significance Index: -0.8400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2254
    Cell Significance Index: -11.7400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2275
    Cell Significance Index: -7.9700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2443
    Cell Significance Index: -6.6500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2538
    Cell Significance Index: -8.3100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2546
    Cell Significance Index: -8.1100
  • Cell Name: colonocyte (CL1000347)
    Fold Change: -0.2557
    Cell Significance Index: -1.5800
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.2591
    Cell Significance Index: -2.8400
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: -0.2603
    Cell Significance Index: -2.8100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2611
    Cell Significance Index: -11.5500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2947
    Cell Significance Index: -14.9000
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.2999
    Cell Significance Index: -4.4900
  • Cell Name: stromal cell of endometrium (CL0002255)
    Fold Change: -0.3037
    Cell Significance Index: -4.3200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3038
    Cell Significance Index: -11.5100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Expression Pattern**: UGT2B7 is predominantly expressed in retinal cells, including photoreceptor cells, bipolar cells, and Müller cells, suggesting a specialized function in the visual system. 2. **Enzyme Specificity**: UGT2B7 has a high specificity for 3,4-catechol estrogens, indicating its potential role in estrogen metabolism. 3. **Glucuronidation Activity**: UGT2B7 is involved in the glucuronidation of various endogenous and exogenous compounds, including steroids, estrogens, and xenobiotics. 4. **Tissue Distribution**: UGT2B7 is also expressed in epithelial cells of the proximal tubule, suggesting its role in kidney function. **Pathways and Functions** 1. **Androgen Metabolic Process**: UGT2B7 is involved in the glucuronidation of androgens, which is essential for their metabolism and elimination. 2. **Estrogen Metabolic Process**: The enzyme's specificity for 3,4-catechol estrogens suggests its role in estrogen metabolism and regulation. 3. **Biological Oxidations**: UGT2B7 is involved in the glucuronidation of various biological oxidations, including the metabolism of steroids and xenobiotics. 4. **Glucuronidation**: The enzyme is a key player in the glucuronidation process, a phase II conjugation reaction that detoxifies and eliminates compounds. 5. **Drug Adme**: UGT2B7 is involved in the glucuronidation of various drugs, which is essential for their metabolism and elimination. **Clinical Significance** 1. **Visual Impairment**: Alterations in UGT2B7 expression or activity may contribute to visual impairment, including age-related macular degeneration and retinitis pigmentosa. 2. **Cancer**: The enzyme's role in estrogen metabolism suggests its potential involvement in cancer development and progression, particularly in estrogen receptor-positive breast cancer. 3. **Kidney Function**: UGT2B7's expression in epithelial cells of the proximal tubule suggests its role in kidney function and disease, including kidney damage and dysfunction. 4. **Xenobiotic Metabolism**: The enzyme's involvement in the glucuronidation of xenobiotics highlights its importance in detoxification and metabolism. In conclusion, UGT2B7 is a crucial enzyme involved in the phase II conjugation of compounds, with significant implications for visual function, cancer, kidney function, and xenobiotic metabolism. Further research is needed to fully elucidate the enzyme's role and clinical significance.

Genular Protein ID: 2746531993

Symbol: UD2B7_HUMAN

Name: 3,4-catechol estrogen-specific UDPGT

UniProtKB Accession Codes:

P16662 B2R810 Q6GTW0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CAZy 1 CCDS 1 CDD 1 CTD 1 ChEBI 100 ChEMBL 1 ChiTaRS 1 ComplexPortal 3 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 90 EC 1 EMBL 5 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 8 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 3 RefSeq 2 Rhea 42 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2159463

Title: Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells. 3,4-catechol estrogens and estriol as primary substrates.

PubMed ID: 2159463

DOI: 10.1016/s0021-9258(19)39016-7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 10702251

Title: 4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7.

PubMed ID: 10702251

DOI: 10.1074/jbc.275.10.6908

PubMed ID: 15472229

Title: Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium.

PubMed ID: 15472229

DOI: 10.1210/jc.2004-0331

PubMed ID: 15470161

Title: Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism.

PubMed ID: 15470161

DOI: 10.1124/dmd.104.001651

PubMed ID: 18674515

Title: The human UDP-glucuronosyltransferase UGT1A3 is highly selective towards N2 in the tetrazole ring of losartan, candesartan, and zolarsartan.

PubMed ID: 18674515

DOI: 10.1016/j.bcp.2008.07.006

PubMed ID: 18177842

Title: Identification of human UDP-glucuronosyltransferases catalyzing hepatic 1alpha,25-dihydroxyvitamin D3 conjugation.

PubMed ID: 18177842

DOI: 10.1016/j.bcp.2007.11.008

PubMed ID: 18719240

Title: The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

PubMed ID: 18719240

DOI: 10.1124/dmd.108.022731

PubMed ID: 19022937

Title: UDP-glucuronosyltransferases (UGTs) 2B7 and UGT2B17 display converse specificity in testosterone and epitestosterone glucuronidation, whereas UGT2A1 conjugates both androgens similarly.

PubMed ID: 19022937

DOI: 10.1124/dmd.108.024844

PubMed ID: 23288867

Title: Regiospecificity and stereospecificity of human UDP-glucuronosyltransferases in the glucuronidation of estriol, 16-epiestriol, 17-epiestriol, and 13-epiestradiol.

PubMed ID: 23288867

DOI: 10.1124/dmd.112.049072

PubMed ID: 23756265

Title: The Human UDP-glucuronosyltransferase UGT2A1 and UGT2A2 enzymes are highly active in bile acid glucuronidation.

PubMed ID: 23756265

DOI: 10.1124/dmd.113.052613

PubMed ID: 26220143

Title: Glucuronidation of estrone and 16alpha-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7.

PubMed ID: 26220143

DOI: 10.1016/j.jsbmb.2015.07.013

PubMed ID: 17442341

Title: Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7.

PubMed ID: 17442341

DOI: 10.1016/j.jmb.2007.03.066

PubMed ID: 11186130

Title: Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance.

PubMed ID: 11186130

DOI: 10.1097/00008571-200011000-00002

Sequence Information:

  • Length: 529
  • Mass: 60721
  • Checksum: 94B8B31CE929C836
  • Sequence:
    • MSVKWTSVIL LIQLSFCFSS GNCGKVLVWA AEYSHWMNIK TILDELIQRG HEVTVLASSA 
SILFDPNNSS ALKIEIYPTS LTKTELENFI MQQIKRWSDL PKDTFWLYFS QVQEIMSIFG 
DITRKFCKDV VSNKKFMKKV QESRFDVIFA DAIFPCSELL AELFNIPFVY SLSFSPGYTF 
EKHSGGFIFP PSYVPVVMSE LTDQMTFMER VKNMIYVLYF DFWFEIFDMK KWDQFYSEVL 
GRPTTLSETM GKADVWLIRN SWNFQFPYPL LPNVDFVGGL HCKPAKPLPK EMEDFVQSSG 
ENGVVVFSLG SMVSNMTEER ANVIASALAQ IPQKVLWRFD GNKPDTLGLN TRLYKWIPQN 
DLLGHPKTRA FITHGGANGI YEAIYHGIPM VGIPLFADQP DNIAHMKARG AAVRVDFNTM 
SSTDLLNALK RVINDPSYKE NVMKLSRIQH DQPVKPLDRA VFWIEFVMRH KGAKHLRVAA 
HDLTWFQYHS LDVIGFLLVC VATVIFIVTK CCLFCFWKFA RKAKKGKND

Genular Protein ID: 2151899829

Symbol: E9PBP8_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PBP8

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 2 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 369
  • Mass: 42660
  • Checksum: 9ED51CA29595DBC7
  • Sequence:
    • MSVKWTSVIL LIQLSFCFSS GNCGKVLVWA AEYSHWMNIK TILDELIQRG HEVTVLASSA 
SILFDPNNSS ALKIEIYPTS LTKTELENFI MQQIKRWSDL PKDTFWLYFS QVQEIMSIFG 
DITRKFCKDV VSNKKFMKKV QESRFDVIFA DAIFPCSELL AELFNIPFVY SLSFSPGYTF 
EKHSGGFIFP PSYVPVVMSE LTDQMTFMER VKNMIYVLYF DFWFEIFDMK KWDQFYSEVL 
GRPTTLSETM GKADVWLIRN SWNFQFPYPL LPNVDFVGGL HCKPAKPLPK EMEDFVQSSG 
ENGVVVFSLG SMVSNMTEER ANVIASALAQ IPQKVLWRFD GNKPDTLGLN TRLYKWIPQN 
DLLDIKRML

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.