Details for: VIPR1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 66.7973
Cell Significance Index: -10.3900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 41.1602
Cell Significance Index: -10.4400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 22.8550
Cell Significance Index: -9.2900 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 15.8564
Cell Significance Index: -10.6400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 8.4188
Cell Significance Index: -10.3800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 3.1778
Cell Significance Index: 604.7600 - Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 3.0060
Cell Significance Index: 21.8000 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 2.2756
Cell Significance Index: 20.9600 - Cell Name: epidermal cell (CL0000362)
Fold Change: 2.1690
Cell Significance Index: 4.8900 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.3775
Cell Significance Index: 20.6400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.2374
Cell Significance Index: 134.6000 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.1992
Cell Significance Index: 240.5700 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 1.1827
Cell Significance Index: 10.2300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.1534
Cell Significance Index: 52.2800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.0418
Cell Significance Index: 30.0200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.9054
Cell Significance Index: 19.6200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.8968
Cell Significance Index: 88.7100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.8793
Cell Significance Index: 158.5100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.8543
Cell Significance Index: 44.3800 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 0.7788
Cell Significance Index: 8.4400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.7266
Cell Significance Index: 50.2500 - Cell Name: pulmonary capillary endothelial cell (CL4028001)
Fold Change: 0.6098
Cell Significance Index: 8.3500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.5508
Cell Significance Index: 28.6900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.5107
Cell Significance Index: 19.3400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.4309
Cell Significance Index: 52.9800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.4197
Cell Significance Index: 11.7300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.3888
Cell Significance Index: 5.3100 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: 0.3008
Cell Significance Index: 4.0100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.2831
Cell Significance Index: 12.5200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2626
Cell Significance Index: 237.1400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.2384
Cell Significance Index: 16.0300 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 0.2072
Cell Significance Index: 2.0900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1937
Cell Significance Index: 9.0300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1682
Cell Significance Index: 74.3600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.1620
Cell Significance Index: 3.4500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1618
Cell Significance Index: 5.6900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1384
Cell Significance Index: 3.4600 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 0.1179
Cell Significance Index: 0.9900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.1029
Cell Significance Index: 11.9900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0968
Cell Significance Index: 3.1000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0962
Cell Significance Index: 2.6200 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: 0.0894
Cell Significance Index: 0.9800 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 0.0712
Cell Significance Index: 0.9500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0563
Cell Significance Index: 11.1700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0467
Cell Significance Index: 0.8000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0465
Cell Significance Index: 3.2900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0448
Cell Significance Index: 16.0900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0413
Cell Significance Index: 1.9400 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.0285
Cell Significance Index: 0.3000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.0156
Cell Significance Index: 0.5100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.0148
Cell Significance Index: 0.4700 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0130
Cell Significance Index: 8.9700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0067
Cell Significance Index: 0.5000 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0034
Cell Significance Index: 0.4400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0027
Cell Significance Index: 0.1700 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0021
Cell Significance Index: -1.1500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0031
Cell Significance Index: -4.2100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0037
Cell Significance Index: -6.9000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0062
Cell Significance Index: -11.4100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0068
Cell Significance Index: -10.4000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0104
Cell Significance Index: -7.8600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0140
Cell Significance Index: -10.3900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0142
Cell Significance Index: -10.4200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0147
Cell Significance Index: -9.3300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0185
Cell Significance Index: -11.5300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0199
Cell Significance Index: -11.2500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0229
Cell Significance Index: -10.4200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0299
Cell Significance Index: -8.6100 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0311
Cell Significance Index: -3.9900 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.0420
Cell Significance Index: -0.4400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0494
Cell Significance Index: -1.2700 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: -0.0502
Cell Significance Index: -0.3100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0542
Cell Significance Index: -11.4200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0553
Cell Significance Index: -8.0400 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0601
Cell Significance Index: -1.5000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0637
Cell Significance Index: -10.8800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0696
Cell Significance Index: -7.1100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0770
Cell Significance Index: -8.8200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0776
Cell Significance Index: -10.6600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0934
Cell Significance Index: -11.0100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1000
Cell Significance Index: -7.6800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1007
Cell Significance Index: -10.4900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1123
Cell Significance Index: -7.2500 - Cell Name: taste receptor cell (CL0000209)
Fold Change: -0.1144
Cell Significance Index: -1.3300 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: -0.1171
Cell Significance Index: -0.7600 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.1181
Cell Significance Index: -0.7700 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: -0.1241
Cell Significance Index: -1.2800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1411
Cell Significance Index: -8.6700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1487
Cell Significance Index: -5.2100 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -0.1502
Cell Significance Index: -1.6600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1671
Cell Significance Index: -10.2500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1686
Cell Significance Index: -4.8100 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.1812
Cell Significance Index: -2.5800 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: -0.1835
Cell Significance Index: -1.8400 - Cell Name: enterocyte (CL0000584)
Fold Change: -0.1886
Cell Significance Index: -1.1700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1898
Cell Significance Index: -10.6500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1926
Cell Significance Index: -10.1100 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2151
Cell Significance Index: -3.0800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.2168
Cell Significance Index: -5.8000 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.2391
Cell Significance Index: -4.4200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 774757882
Symbol: VIPR1_HUMAN
Name: Vasoactive intestinal polypeptide receptor 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8390245
Title: Cloning and functional expression of a human neuroendocrine vasoactive intestinal peptide receptor.
PubMed ID: 8390245
PubMed ID: 8179610
Title: Human intestinal VIP receptor: cloning and functional expression of two cDNA encoding proteins with different N-terminal domains.
PubMed ID: 8179610
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7917790
Title: Molecular cloning and functional characterization of a human liver vasoactive intestinal peptide receptor.
PubMed ID: 7917790
PubMed ID: 7818527
Title: Highly conserved aspartate 68, tryptophan 73 and glycine 109 in the N-terminal extracellular domain of the human VIP receptor are essential for its ability to bind VIP.
PubMed ID: 7818527
PubMed ID: 8926282
Title: Predominant expression of type II vasoactive intestinal peptide receptors by human T lymphoblastoma cells: transduction of both Ca2+ and cyclic AMP signals.
PubMed ID: 8926282
DOI: 10.1007/bf01540969
PubMed ID: 9928020
Title: Importance of conserved cysteines in the extracellular loops of human PACAP/VIP1 receptor for ligand binding and stimulation of cAMP production.
PubMed ID: 9928020
PubMed ID: 14734527
Title: Dual, HLA-B27 subtype-dependent conformation of a self-peptide.
PubMed ID: 14734527
DOI: 10.1084/jem.20031690
PubMed ID: 18650441
Title: Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes.
PubMed ID: 18650441
Sequence Information:
- Length: 457
- Mass: 51547
- Checksum: DAA40CF5BEC47D7D
- Sequence:
MRPPSPLPAR WLCVLAGALA WALGPAGGQA ARLQEECDYV QMIEVQHKQC LEEAQLENET IGCSKMWDNL TCWPATPRGQ VVVLACPLIF KLFSSIQGRN VSRSCTDEGW THLEPGPYPI ACGLDDKAAS LDEQQTMFYG SVKTGYTIGY GLSLATLLVA TAILSLFRKL HCTRNYIHMH LFISFILRAA AVFIKDLALF DSGESDQCSE GSVGCKAAMV FFQYCVMANF FWLLVEGLYL YTLLAVSFFS ERKYFWGYIL IGWGVPSTFT MVWTIARIHF EDYGCWDTIN SSLWWIIKGP ILTSILVNFI LFICIIRILL QKLRPPDIRK SDSSPYSRLA RSTLLLIPLF GVHYIMFAFF PDNFKPEVKM VFELVVGSFQ GFVVAILYCF LNGEVQAELR RKWRRWHLQG VLGWNPKYRH PSGGSNGATC STQVSMLTRV SPGARRSSSF QAEVSLV
Genular Protein ID: 1210994378
Symbol: B4DNY6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 430
- Mass: 48881
- Checksum: 8C11AC117BBB8E5E
- Sequence:
MRAGRLQEEC DYVQMIEVQH KQCLEEAQLE NETIGCSKMW DNLTCWPATP RGQVVVLACP LIFKLFSSIQ GRNVSRSCTD EGWTHLEPGP YPIACGLDDK AASLDEQQTM FYGSVKTGYT IGYGLSLATL LVATAILSLF RKLHCTRNYI HMHLFISFIL RAAAVFIKDL ALFDSGESDQ CSEGSVGCKA AMVFFQYCVM ANFFWLLVEG LYLYTLLAVS FFSERKYFWG YILIGWGVPS TFTMVWTIAR IHFEDYGCWD TINSSLWWII KGPILTSILV NFILFICIIR ILLQKLRPPD IRKSDSSPYS RLARSTLLLI PLFGVHYIMF AFFPDNFKPE VKMVFELVVG SFQGFVVAIL YCFLNGEVQA ELRRKWRRWH LQGVLGWNPK YRHPSGGSNG ATCSTQVSML TRVSPGARRS SSFQAEVSLV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.