Details for: ZFX
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 234.4656
Cell Significance Index: -36.4700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 142.7201
Cell Significance Index: -36.2000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 84.5543
Cell Significance Index: -39.9200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 82.4601
Cell Significance Index: -33.5000 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 73.6607
Cell Significance Index: -37.8900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 35.3289
Cell Significance Index: -33.7300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 31.1852
Cell Significance Index: -38.4500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 13.9500
Cell Significance Index: -37.3700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 11.2173
Cell Significance Index: -24.5500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 10.1288
Cell Significance Index: -31.1100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.8668
Cell Significance Index: -38.9400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.8041
Cell Significance Index: 358.0200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.7973
Cell Significance Index: 47.9900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.4121
Cell Significance Index: 1275.0100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.2574
Cell Significance Index: 32.3200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 1.2137
Cell Significance Index: 141.4400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.0431
Cell Significance Index: 209.2400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.0256
Cell Significance Index: 57.5500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.9349
Cell Significance Index: 101.6900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.9347
Cell Significance Index: 71.7300 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.8515
Cell Significance Index: 18.2000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.7178
Cell Significance Index: 20.0600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.7024
Cell Significance Index: 251.9300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.6793
Cell Significance Index: 43.8300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.6228
Cell Significance Index: 85.5300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.5672
Cell Significance Index: 16.2600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.5312
Cell Significance Index: 234.8600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.5087
Cell Significance Index: 6.9400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.4534
Cell Significance Index: 313.5900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4353
Cell Significance Index: 30.1000 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.4248
Cell Significance Index: 8.2900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.4102
Cell Significance Index: 50.4400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3970
Cell Significance Index: 71.5600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.3300
Cell Significance Index: 20.8000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3296
Cell Significance Index: 180.0000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2645
Cell Significance Index: 5.7300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.2487
Cell Significance Index: 11.6900 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2343
Cell Significance Index: 30.0400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.2306
Cell Significance Index: 16.3100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2267
Cell Significance Index: 43.1500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1772
Cell Significance Index: 4.4300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.1390
Cell Significance Index: 6.1500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1333
Cell Significance Index: 6.0400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1117
Cell Significance Index: 5.2100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.1071
Cell Significance Index: 12.6300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.0927
Cell Significance Index: 3.5100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0812
Cell Significance Index: 51.5800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0622
Cell Significance Index: 10.6200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0507
Cell Significance Index: 95.3800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0471
Cell Significance Index: 4.6600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0390
Cell Significance Index: 17.6900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0345
Cell Significance Index: 53.0900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0268
Cell Significance Index: 0.4600 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0248
Cell Significance Index: 0.6700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0241
Cell Significance Index: 1.4800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0207
Cell Significance Index: 1.3900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0182
Cell Significance Index: 0.6400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0163
Cell Significance Index: 30.0900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0125
Cell Significance Index: 17.0100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0149
Cell Significance Index: -11.0300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0189
Cell Significance Index: -11.8000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0231
Cell Significance Index: -16.9700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0314
Cell Significance Index: -4.5700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0370
Cell Significance Index: -28.0000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0456
Cell Significance Index: -0.6700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0522
Cell Significance Index: -2.7100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0540
Cell Significance Index: -30.4400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0620
Cell Significance Index: -8.0100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0740
Cell Significance Index: -3.8600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1167
Cell Significance Index: -24.5800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1173
Cell Significance Index: -33.7500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1224
Cell Significance Index: -12.5100 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.1263
Cell Significance Index: -1.0300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1417
Cell Significance Index: -16.2400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1761
Cell Significance Index: -3.7500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1795
Cell Significance Index: -13.3800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1988
Cell Significance Index: -5.4100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2136
Cell Significance Index: -24.3800 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2411
Cell Significance Index: -6.3400 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.2822
Cell Significance Index: -1.7100 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2885
Cell Significance Index: -14.5800 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.2903
Cell Significance Index: -3.4600 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.3271
Cell Significance Index: -7.9800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3340
Cell Significance Index: -34.7800 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.3416
Cell Significance Index: -5.7600 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.3833
Cell Significance Index: -3.2200 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.3934
Cell Significance Index: -5.6500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4136
Cell Significance Index: -32.7600 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.4242
Cell Significance Index: -8.8000 - Cell Name: peg cell (CL4033014)
Fold Change: -0.4242
Cell Significance Index: -9.8000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4259
Cell Significance Index: -22.3600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.4399
Cell Significance Index: -14.0900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.5509
Cell Significance Index: -19.1500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.5795
Cell Significance Index: -35.5300 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.6188
Cell Significance Index: -14.8400 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.6602
Cell Significance Index: -9.7500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.6793
Cell Significance Index: -18.1700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.7075
Cell Significance Index: -11.8400 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.7186
Cell Significance Index: -10.3400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.7664
Cell Significance Index: -24.4100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2119579092
Symbol: ZFX_HUMAN
Name: Zinc finger X-chromosomal protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2512506
Title: Putative transcription activator with alternative isoforms encoded by human ZFX gene.
PubMed ID: 2512506
DOI: 10.1038/342708a0
PubMed ID: 2308929
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2500252
Title: ZFX has a gene structure similar to ZFY, the putative human sex determinant, and escapes X inactivation.
PubMed ID: 2500252
PubMed ID: 2041734
Title: Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY.
PubMed ID: 2041734
PubMed ID: 38325380
Title: Variants in ZFX are associated with an X-linked neurodevelopmental disorder with recurrent facial gestalt.
PubMed ID: 38325380
Sequence Information:
- Length: 805
- Mass: 90522
- Checksum: B074079D1762A0AD
- Sequence:
MDEDGLELQQ EPNSFFDATG ADGTHMDGDQ IVVEVQETVF VSDVVDSDIT VHNFVPDDPD SVVIQDVIED VVIEDVQCPD IMEEADVSET VIIPEQVLDS DVTEEVSLAH CTVPDDVLAS DITSASMSMP EHVLTGDSIH VSDVGHVGHV GHVEHVVHDS VVEAEIVTDP LTTDVVSEEV LVADCASEAV IDANGIPVDQ QDDDKGNCED YLMISLDDAG KIEHDGSSGM TMDTESEIDP CKVDGTCPEV IKVYIFKADP GEDDLGGTVD IVESEPENDH GVELLDQNSS IRVPREKMVY MTVNDSQPED EDLNVAEIAD EVYMEVIVGE EDAAAAAAAA AVHEQQMDDN EIKTFMPIAW AAAYGNNSDG IENRNGTASA LLHIDESAGL GRLAKQKPKK RRRPDSRQYQ TAIIIGPDGH PLTVYPCMIC GKKFKSRGFL KRHMKNHPEH LAKKKYRCTD CDYTTNKKIS LHNHLESHKL TSKAEKAIEC DECGKHFSHA GALFTHKMVH KEKGANKMHK CKFCEYETAE QGLLNRHLLA VHSKNFPHIC VECGKGFRHP SELKKHMRIH TGEKPYQCQY CEYRSADSSN LKTHVKTKHS KEMPFKCDIC LLTFSDTKEV QQHALIHQES KTHQCLHCDH KSSNSSDLKR HIISVHTKDY PHKCDMCDKG FHRPSELKKH VAAHKGKKMH QCRHCDFKIA DPFVLSRHIL SVHTKDLPFR CKRCRKGFRQ QSELKKHMKT HSGRKVYQCE YCEYSTTDAS GFKRHVISIH TKDYPHRCEY CKKGFRRPSE KNQHIMRHHK EVGLP
Genular Protein ID: 1575065747
Symbol: Q8WXB7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15060604
Title: Cloning and comparative analysis of the bovine, porcine, and equine sex chromosome genes ZFX and ZFY.
PubMed ID: 15060604
DOI: 10.1139/g03-099
Sequence Information:
- Length: 543
- Mass: 62470
- Checksum: A6A2A01A55155847
- Sequence:
DDLCGTVDIV ESEPENDHGV ELLDQNSSIR VPREKMVYMT VNDSQPEDED LNVAEIADEV YMEVIVGEED AAAAAAAAAV HEQQMDDNEI KTFMPIAWAA AYGNNSDGIE NRNGTASALL HIDESAGLGR LAKQKPKKRR RPDSRQYQTA IIIGPDGHPL TVYPCMICGK KFKSRGFLKR HMKNHPEHLA KKKYRCTDCD YTTNKKISLH NHLESHKLTS KAEKAIECDE CGKHFSHAGA LFTHKMVHKE KGANKMHKCK FCEYETAEQG LLNRHLLAVH SKNFPHICVE CGKGFRHPSE LKKHMRIHTG EKPYQCQYCE YRSADSSNLK THVKTMHSKE MPFKCDICLL TFSDTKEVQQ HALIHQESKT HQCLHCDHKS SNSSDLKRHI ISVHTKDYPH KCDMCDKGFH RPSELKKHVA AHKGKKMHQC RHCDFKIADP FVLSRHILSV HTKDLPFRCK RCRKGFRQQS ELKKHMKTHS GRKVYQCEYC EYSTTDASGF KRHVISIHTK DYPHRCEYCK KGFRRPSEKN QHIMRHHKEV GLP
Genular Protein ID: 232227651
Symbol: Q59EB9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 436
- Mass: 47240
- Checksum: 54060E688A8B7DDE
- Sequence:
ELKAMDEDGL ELQQEPNSFF DATGADGTHM DGDQIVVEVQ ETVFVSDVVD SDITVHNFVP DDPDSVVIQD VIEDVVIEDV QCPDIMEEAD VSETVIIPEQ VLDSDVTEEV SLAHCTVPDD VLASDITSAS MSMPEHVLTG DSIHVSDVGH VGHVGHVEHV VHDSVVEAEI VTDPLTTDVV SEEVLVADCA SEAVIDANGI PVDQQDDDKG NCEDYLMISL DDAGKIEHDG SSGMTMDTES EIDPCKVDGT CPEVIKVYIF KADPGEDDLG GTVDIVESEP ENDHGVELLD QNSSIRVPRE KMVYMTVNDS QPEDEDLNVA EIADEVYMEV IVGEEDAAAA AAAAAVHEQQ MDDNEIKTFM PIAWAAAYGN NSDGIENRNG TASALLHIDE SAGLGRLAKQ KPKKRRRPDS RQYQTGEGAR VPWRSVLCEL SEETLQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.