Details for: ZNF142

Gene ID: 7701

Symbol: ZNF142

Ensembl ID: ENSG00000115568

Description: zinc finger protein 142

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 68.5974
    Cell Significance Index: -10.6700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 42.9737
    Cell Significance Index: -10.9000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 22.5719
    Cell Significance Index: -9.1700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 8.9460
    Cell Significance Index: -11.0300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.0708
    Cell Significance Index: -10.9100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.8180
    Cell Significance Index: -11.1200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.1384
    Cell Significance Index: -4.6800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0977
    Cell Significance Index: 208.8900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.8396
    Cell Significance Index: 83.0600
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.6851
    Cell Significance Index: 11.2900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5632
    Cell Significance Index: 508.5200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.5079
    Cell Significance Index: 6.9300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4441
    Cell Significance Index: 48.3100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4408
    Cell Significance Index: 87.4700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4228
    Cell Significance Index: 68.7700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3869
    Cell Significance Index: 23.2300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.3622
    Cell Significance Index: 9.3100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3193
    Cell Significance Index: 64.0500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2857
    Cell Significance Index: 6.1900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2582
    Cell Significance Index: 7.4400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2016
    Cell Significance Index: 13.9400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1964
    Cell Significance Index: 8.9000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1757
    Cell Significance Index: 4.9100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1672
    Cell Significance Index: 30.1400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1655
    Cell Significance Index: 59.3800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1628
    Cell Significance Index: 3.5700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1490
    Cell Significance Index: 103.0600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1302
    Cell Significance Index: 15.1700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1260
    Cell Significance Index: 3.3800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1249
    Cell Significance Index: 7.8800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1233
    Cell Significance Index: 9.4700
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.1083
    Cell Significance Index: 1.5200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1036
    Cell Significance Index: 12.7400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0880
    Cell Significance Index: 4.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0872
    Cell Significance Index: 12.6800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0829
    Cell Significance Index: 4.6500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0663
    Cell Significance Index: 1.6600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0463
    Cell Significance Index: 20.4700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0402
    Cell Significance Index: 21.9400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0359
    Cell Significance Index: 1.2600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0266
    Cell Significance Index: 3.1400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0206
    Cell Significance Index: 0.9600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0071
    Cell Significance Index: 0.9800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0060
    Cell Significance Index: 11.3900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0045
    Cell Significance Index: 8.3800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0011
    Cell Significance Index: 1.7000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0006
    Cell Significance Index: 0.0400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0002
    Cell Significance Index: 0.1400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0014
    Cell Significance Index: -0.0200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0019
    Cell Significance Index: -2.5500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0041
    Cell Significance Index: -1.8500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0054
    Cell Significance Index: -0.6900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0101
    Cell Significance Index: -1.7300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0107
    Cell Significance Index: -7.8700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0123
    Cell Significance Index: -9.0900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0130
    Cell Significance Index: -9.8400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0190
    Cell Significance Index: -10.7100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0193
    Cell Significance Index: -12.0500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0211
    Cell Significance Index: -1.1000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0259
    Cell Significance Index: -1.7400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0296
    Cell Significance Index: -0.6300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0315
    Cell Significance Index: -9.0600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0345
    Cell Significance Index: -2.1200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0409
    Cell Significance Index: -4.1800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0422
    Cell Significance Index: -4.8300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0448
    Cell Significance Index: -1.9800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0566
    Cell Significance Index: -3.6500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0569
    Cell Significance Index: -7.3500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0575
    Cell Significance Index: -12.1200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0591
    Cell Significance Index: -1.6100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0598
    Cell Significance Index: -1.2400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0599
    Cell Significance Index: -1.1700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0610
    Cell Significance Index: -2.3100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0733
    Cell Significance Index: -5.4600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0734
    Cell Significance Index: -3.4500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0764
    Cell Significance Index: -2.0400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1007
    Cell Significance Index: -10.4900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1246
    Cell Significance Index: -2.1400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1267
    Cell Significance Index: -10.0400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1336
    Cell Significance Index: -8.1900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1489
    Cell Significance Index: -7.8200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.1742
    Cell Significance Index: -2.6100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1754
    Cell Significance Index: -5.0100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1773
    Cell Significance Index: -5.6800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.1988
    Cell Significance Index: -2.9400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2026
    Cell Significance Index: -5.4200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2054
    Cell Significance Index: -5.4000
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.2057
    Cell Significance Index: -3.3000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2068
    Cell Significance Index: -6.7700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2119
    Cell Significance Index: -6.7500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2160
    Cell Significance Index: -5.1800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2273
    Cell Significance Index: -6.6800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2322
    Cell Significance Index: -11.7300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2361
    Cell Significance Index: -8.2700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2374
    Cell Significance Index: -8.2500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2486
    Cell Significance Index: -3.6700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2502
    Cell Significance Index: -7.3700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2568
    Cell Significance Index: -5.4500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2605
    Cell Significance Index: -4.3600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2632
    Cell Significance Index: -7.5500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Transcriptional Regulation:** ZNF142 acts as a transcriptional regulator, influencing the expression of target genes through its interaction with RNA polymerase II. 2. **DNA Binding:** The protein exhibits specific DNA binding affinity, enabling it to recognize and bind to particular DNA sequences. 3. **Cellular Expression:** ZNF142 is widely expressed in various cell types, including choroid plexus epithelial cells, cerebral cortex GABAergic interneurons, and intestinal epithelial cells. 4. **Metal Binding:** The protein contains a metal-binding domain, which may contribute to its DNA binding activity and stability. **Pathways and Functions:** 1. **RNA Polymerase II-Specific Transcription Regulation:** ZNF142 interacts with RNA polymerase II, modulating the expression of target genes involved in transcriptional regulation. 2. **DNA Binding Transcription Factor Activity:** The protein exhibits DNA binding activity, influencing the expression of genes involved in cellular differentiation and proliferation. 3. **Metal Ion Binding:** The metal-binding domain of ZNF142 may contribute to its DNA binding activity and stability. 4. **Regulation of Transcription by RNA Polymerase II:** ZNF142 regulates transcriptional activity by interacting with RNA polymerase II, modulating the expression of target genes. **Clinical Significance:** 1. **Developmental Disorders:** Alterations in ZNF142 expression have been linked to developmental disorders, such as neurodevelopmental disorders and congenital anomalies. 2. **Cancer:** Aberrant expression of ZNF142 has been observed in various types of cancer, suggesting its potential role in tumorigenesis and cancer progression. 3. **Neurological Disorders:** ZNF142 may play a role in neurological disorders, including epilepsy, schizophrenia, and Alzheimer's disease. 4. **Intestinal Health:** Dysregulation of ZNF142 expression has been linked to intestinal disorders, such as inflammatory bowel disease and colorectal cancer. In conclusion, ZNF142 is a transcriptional regulator that plays a crucial role in various cellular processes, including development, homeostasis, and disease regulation. Further studies are necessary to elucidate the mechanisms by which ZNF142 influences gene expression and to explore its potential therapeutic applications in various diseases.

Genular Protein ID: 4056833296

Symbol: ZN142_HUMAN

Name: N/A

UniProtKB Accession Codes:

P52746 Q92510

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 1 ExpressionAtlas 1 GO 5 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 3 SMART 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9039502

Title: Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.

PubMed ID: 9039502

DOI: 10.1093/dnares/3.5.321

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 7557990

Title: Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

PubMed ID: 7557990

DOI: 10.1006/geno.1995.1040

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 31036918

Title: Recessive variants in ZNF142 cause a complex neurodevelopmental disorder with intellectual disability, speech impairment, seizures, and dystonia.

PubMed ID: 31036918

DOI: 10.1038/s41436-019-0523-0

Sequence Information:

  • Length: 1687
  • Mass: 187880
  • Checksum: 91143EAF2481B6B3
  • Sequence:
    • MTDPLLDSQP ASSTGEMDGL CPELLLIPPP LSNRGILGPV QSPCPSRDPA PIPTEPGCLL 
VEATATEEGP GNMEIIVETV AGTLTPGAPG ETPAPKLPPG EREPSQEAGT PLPGQETAEE 
ENVEKEEKSD TQKDSQKAVD KGQGAQRLEG DVVSGTESLF KTHMCPECKR CFKKRTHLVE 
HLHLHFPDPS LQCPNCQKFF TSKSKLKTHL LRELGEKAHH CPLCHYSAVE RNALNRHMAS 
MHEDISNFYS DTYACPVCRE EFRLSQALKE HLKSHTAAAA AEPLPLRCFQ EGCSYAAPDR 
KAFIKHLKET HGVRAVECRH HSCPMLFATA EAMEAHHKSH YAFHCPHCDF ACSNKHLFRK 
HKKQGHPGSE ELRCTFCPFA TFNPVAYQDH VGKMHAHEKI HQCPECNFAT AHKRVLIRHM 
LLHTGEKPHK CELCDFTCRD VSYLSKHMLT HSNTKDYMCT ECGYVTKWKH YLRVHMRKHA 
GDLRYQCNQC SYRCHRADQL SSHKLRHQGK SLMCEVCAFA CKRKYELQKH MASQHHPGTP 
APLYPCHYCS YQSRHKQAVL SHENCKHTRL REFHCALCDY RTFSNTTLLF HKRKAHGYVP 
GDQAWQLRYA SQEPEGAMQG PTPPPDSEPS NQLSARPEGP GHEPGTVVDP SLDQALPEMS 
EEVNTGRQEG SEAPHGGDLG GSPSPAEVEE GSCTLHLEAL GVELESVTEP PLEEVTETAP 
MEFRPLGLEG PDGLEGPELS SFEGIGTSDL SAEENPLLEK PVSEPSTNPP SLEEAPNNWV 
GTFKTTPPAE TAPLPPLPES ESLLKALRRQ DKEQAEALVL EGRVQMVVIQ GEGRAFRCPH 
CPFITRREKA LNLHSRTGCQ GRREPLLCPE CGASFKQQRG LSTHLLKKCP VLLRKNKGLP 
RPDSPIPLQP VLPGTQASED TESGKPPPAS QEAELLLPKD APLELPREPE ETEEPLATVS 
GSPVPPAGNS LPTEAPKKHC FDPVPPAGNS SPTEAPKKHH LDPVPPAGNS SPTEALKKHR 
FEQGKFHCNS CPFLCSRLSS ITSHVAEGCR GGRGGGGKRG TPQTQPDVSP LSNGDSAPPK 
NGSTESSSGD GDTVLVQKQK GARFSCPTCP FSCQQERALR THQIRGCPLE ESGELHCSLC 
PFTAPAATAL RLHQKRRHPT AAPARGPRPH LQCGDCGFTC KQSRCMQQHR RLKHEGVKPH 
QCPFCDFSTT RRYRLEAHQS RHTGIGRIPC SSCPQTFGTN SKLRLHRLRV HDKTPTHFCP 
LCDYSGYLRH DITRHVNSCH QGTPAFACSQ CEAQFSSETA LKQHALRRHP EPAQPAPGSP 
AETTEGPLHC SRCGLLCPSP ASLRGHTRKQ HPRLECGACQ EAFPSRLALD EHRRQQHFSH 
RCQLCDFAAR ERVGLVKHYL EQHEETSAAV AASDGDGDAG QPPLHCPFCD FTCRHQLVLD 
HHVKGHGGTR LYKCTDCAYS TKNRQKITWH SRIHTGEKPY HCHLCPYACA DPSRLKYHMR 
IHKEERKYLC PECGYKCKWV NQLKYHMTKH TGLKPYQCPE CEYCTNRADA LRVHQETRHR 
EARAFMCEQC GKAFKTRFLL RTHLRKHSEA KPYVCNVCHR AFRWAAGLRH HALTHTDRHP 
FFCRLCNYKA KQKFQVVKHV RRHHPDQADP NQGVGKDPTT PTVHLHDVQL EDPSPPAPAA 
PHTGPEG

Genular Protein ID: 2543704826

Symbol: A0A7P0N7C4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A7P0N7C4

Database IDs:

ARBA 1 Bgee 1 CTD 1 DisGeNET 1 EMBL 2 Ensembl 2 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MANE-Select 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 7 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 1887
  • Mass: 209781
  • Checksum: 9363B6953E9D240A
  • Sequence:
    • MTDPLLDSQP ASSTGEMDGL CPELLLIPPP LSNRGILGPV QSPCPSRDPA PIPTEPGCLL 
VEATATEEGP GNMEIIVETV AGTLTPGAPG ETPGVLVKVV EVYFCERCEQ SFAEPTLLAL 
HQCSETHIQP VQGLSSPPCS VELPPSNPTL PGPLQGQSPP VSPLSCPVCR QEFAQPQALK 
SHFKIHRGTP DTFSCPESGC VFSAEDRKGL QHHLRQTHRA VPVPCSFRGC PLLFGSQQGM 
ELHRQAHYPF HCSHCSFIGS NVKLFRQHQR SHGAGTQGEL SAVQGLPSQE LLPAPKLPPG 
EREPSQEAGT PLPGQETAEE ENVEKEEKSD TQKDSQKAVD KGQGAQRLEG DVVSGTESLF 
KTHMCPECKR CFKKRTHLVE HLHLHFPDPS LQCPNCQKFF TSKSKLKTHL LRELGEKAHH 
CPLCHYSAVE RNALNRHMAS MHEDISNFYS DTYACPVCRE EFRLSQALKE HLKSHTAAAA 
AEPLPLRCFQ EGCSYAAPDR KAFIKHLKET HGVRAVECRH HSCPMLFATA EAMEAHHKSH 
YAFHCPHCDF ACSNKHLFRK HKKQGHPGSE ELRCTFCPFA TFNPVAYQDH VGKMHAHEKI 
HQCPECNFAT AHKRVLIRHM LLHTGEKPHK CELCDFTCRD VSYLSKHMLT HSNTKDYMCT 
ECGYVTKWKH YLRVHMRKHA GDLRYQCNQC SYRCHRADQL SSHKLRHQGK SLMCEVCAFA 
CKRKYELQKH MASQHHPGTP APLYPCHYCS YQSRHKQAVL SHENCKHTRL REFHCALCDY 
RTFSNTTLLF HKRKAHGYVP GDQAWQLRYA SQEPEGAMQG PTPPPDSEPS NQLSARPEGP 
GHEPGTVVDP SLDQALPEMS EEVNTGRQEG SEAPHGGDLG GSPSPAEVEE GSCTLHLEAL 
GVELESVTEP PLEEVTETAP MEFRPLGLEG PDGLEGPELS SFEGIGTSDL SAEENPLLEK 
PVSEPSTNPP SLEEAPNNWV GTFKTTPPAE TAPLPPLPES ESLLKALRRQ DKEQAEALVL 
EGRVQMVVIQ GEGRAFRCPH CPFITRREKA LNLHSRTGCQ GRREPLLCPE CGASFKQQRG 
LSTHLLKKCP VLLRKNKGLP RPDSPIPLQP VLPGTQASED TESGKPPPAS QEAELLLPKD 
APLELPREPE ETEEPLATVS GSPVPPAGNS LPTEAPKKHC FDPVPPAGNS SPTEAPKKHH 
LDPVPPAGNS SPTEALKKHR FEQGKFHCNS CPFLCSRLSS ITSHVAEGCR GGRGGGGKRG 
TPQTQPDVSP LSNGDSAPPK NGSTESSSGD GDTVLVQKQK GARFSCPTCP FSCQQERALR 
THQIRGCPLE ESGELHCSLC PFTAPAATAL RLHQKRRHPT AAPARGPRPH LQCGDCGFTC 
KQSRCMQQHR RLKHEGVKPH QCPFCDFSTT RRYRLEAHQS RHTGIGRIPC SSCPQTFGTN 
SKLRLHRLRV HDKTPTHFCP LCDYSGYLRH DITRHVNSCH QGTPAFACSQ CEAQFSSETA 
LKQHALRRHP EPAQPAPGSP AETTEGPLHC SRCGLLCPSP ASLRGHTRKQ HPRLECGACQ 
EAFPSRLALD EHRRQQHFSH RCQLCDFAAR ERVGLVKHYL EQHEETSAAV AASDGDGDAG 
QPPLHCPFCD FTCRHQLVLD HHVKGHGGTR LYKCTDCAYS TKNRQKITWH SRIHTGEKPY 
HCHLCPYACA DPSRLKYHMR IHKEERKYLC PECGYKCKWV NQLKYHMTKH TGLKPYQCPE 
CEYCTNRADA LRVHQETRHR EARAFMCEQC GKAFKTRFLL RTHLRKHSEA KPYVCNVCHR 
AFRWAAGLRH HALTHTDRHP FFCRLCNYKA KQKFQVVKHV RRHHPDQADP NQGVGKDPTT 
PTVHLHDVQL EDPSPPAPAA PHTGPEG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.