Details for: ZBTB17

Gene ID: 7709

Symbol: ZBTB17

Ensembl ID: ENSG00000116809

Description: zinc finger and BTB domain containing 17

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 99.8423
    Cell Significance Index: -15.5300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 57.2852
    Cell Significance Index: -14.5300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 35.5686
    Cell Significance Index: -14.4500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 15.2188
    Cell Significance Index: -14.5300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 13.1878
    Cell Significance Index: -16.2600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 5.4277
    Cell Significance Index: -14.5400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.1662
    Cell Significance Index: -16.4400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9701
    Cell Significance Index: 875.9400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6232
    Cell Significance Index: 101.3500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.6223
    Cell Significance Index: 8.4900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5820
    Cell Significance Index: 63.3100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4009
    Cell Significance Index: 24.0700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3499
    Cell Significance Index: 10.0800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3259
    Cell Significance Index: 7.0600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3052
    Cell Significance Index: 21.1100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2940
    Cell Significance Index: 58.9700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2557
    Cell Significance Index: 50.7400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2057
    Cell Significance Index: 5.7500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2023
    Cell Significance Index: 9.1700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2013
    Cell Significance Index: 36.2800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1915
    Cell Significance Index: 18.9400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1592
    Cell Significance Index: 57.1200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1566
    Cell Significance Index: 108.3200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1377
    Cell Significance Index: 75.1900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1275
    Cell Significance Index: 6.6400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1174
    Cell Significance Index: 9.0100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1154
    Cell Significance Index: 5.3800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1037
    Cell Significance Index: 6.6900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1036
    Cell Significance Index: 5.3800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1010
    Cell Significance Index: 13.8700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0859
    Cell Significance Index: 37.9900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0851
    Cell Significance Index: 10.4700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0810
    Cell Significance Index: 4.9800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0797
    Cell Significance Index: 4.4700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0733
    Cell Significance Index: 8.6500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0705
    Cell Significance Index: 1.1800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0579
    Cell Significance Index: 11.0200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0493
    Cell Significance Index: 3.1100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0424
    Cell Significance Index: 5.4400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0383
    Cell Significance Index: 1.3500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0125
    Cell Significance Index: 2.1300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0020
    Cell Significance Index: 0.0300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0019
    Cell Significance Index: 3.6500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0019
    Cell Significance Index: 0.0400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0013
    Cell Significance Index: 2.0500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0007
    Cell Significance Index: 1.2300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0002
    Cell Significance Index: 0.1400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0028
    Cell Significance Index: -0.2100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0030
    Cell Significance Index: -0.0800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0047
    Cell Significance Index: -0.6100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0049
    Cell Significance Index: -0.1700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0055
    Cell Significance Index: -7.4400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0058
    Cell Significance Index: -0.1500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0121
    Cell Significance Index: -5.4900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0138
    Cell Significance Index: -10.1300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0152
    Cell Significance Index: -11.5200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0160
    Cell Significance Index: -0.4400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0172
    Cell Significance Index: -0.8100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0193
    Cell Significance Index: -14.2900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0195
    Cell Significance Index: -2.8300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0277
    Cell Significance Index: -15.6000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0293
    Cell Significance Index: -18.3100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0366
    Cell Significance Index: -0.7800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0401
    Cell Significance Index: -4.1000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0427
    Cell Significance Index: -12.2900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0534
    Cell Significance Index: -6.2200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0634
    Cell Significance Index: -4.2600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0672
    Cell Significance Index: -3.5300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0848
    Cell Significance Index: -2.4300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0853
    Cell Significance Index: -9.7700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0866
    Cell Significance Index: -18.2400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0909
    Cell Significance Index: -2.3900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1033
    Cell Significance Index: -7.3100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1133
    Cell Significance Index: -5.0100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1134
    Cell Significance Index: -3.3300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1151
    Cell Significance Index: -2.5200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1205
    Cell Significance Index: -2.5800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1227
    Cell Significance Index: -3.9300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1347
    Cell Significance Index: -3.4400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1424
    Cell Significance Index: -2.4400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1506
    Cell Significance Index: -15.6800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1595
    Cell Significance Index: -6.0400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1836
    Cell Significance Index: -14.5400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1982
    Cell Significance Index: -5.3100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2259
    Cell Significance Index: -13.8500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2331
    Cell Significance Index: -5.5900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.2919
    Cell Significance Index: -2.3800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.3147
    Cell Significance Index: -4.4800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3176
    Cell Significance Index: -5.8700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.3180
    Cell Significance Index: -5.6200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.3183
    Cell Significance Index: -3.4600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3242
    Cell Significance Index: -3.8700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3380
    Cell Significance Index: -4.9900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3397
    Cell Significance Index: -10.8200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3410
    Cell Significance Index: -9.7300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3464
    Cell Significance Index: -11.3400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3477
    Cell Significance Index: -12.1800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3572
    Cell Significance Index: -5.1200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3765
    Cell Significance Index: -11.0900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3792
    Cell Significance Index: -7.4000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ZBTB17 is a member of the BTB/POZ family of transcription factors, which are characterized by the presence of a BTB domain and a POZ domain. These domains are essential for the recognition and binding to specific DNA sequences, allowing ZBTB17 to regulate gene expression. The gene is highly expressed in various cell types, including germ cells, cardiac muscle cells, and immune cells such as GABAergic interneurons and intestinal epithelial cells. ZBTB17 has been shown to interact with other transcription factors, such as NF-κB and IRF3, to modulate the expression of target genes. **Pathways and Functions:** ZBTB17 is involved in multiple signaling pathways, including the unfolded protein response (UPR) and the unfolded protein response-mediated apoptosis (UPRap). The UPR is a stress response pathway that is activated in response to endoplasmic reticulum (ER) stress, and ZBTB17 has been shown to regulate the expression of chaperone genes involved in this pathway. Additionally, ZBTB17 has been implicated in the regulation of immune responses, including the production of cytokines and the activation of immune cells. The gene has also been shown to play a role in cell cycle regulation, particularly in the G1 to G0 transition, and in the development of the ectoderm. **Clinical Significance:** ZBTB17 has been implicated in various immune-related disorders, including autoimmune diseases and cancer. For example, studies have shown that ZBTB17 is overexpressed in certain types of cancer, such as gastric cancer, and that its expression is associated with poor prognosis. Additionally, ZBTB17 has been shown to play a role in the regulation of immune responses in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Furthermore, ZBTB17 has been identified as a potential therapeutic target for the treatment of certain types of cancer and autoimmune diseases. **Proteins and Signaling Pathways:** Two proteins have been identified as being associated with ZBTB17, including ZBT17_HUMAN and Q53EM1_HUMAN. These proteins are involved in various signaling pathways, including the UPR and the unfolded protein response-mediated apoptosis (UPRap). The gene has also been shown to interact with other transcription factors, such as NF-κB and IRF3, to modulate the expression of target genes. **Significantly Expressed Cells:** ZBTB17 is highly expressed in various cell types, including: * Germ cells * Cardiac muscle myoblasts * Cerebral cortex GABAergic interneurons * Forebrain radial glial cells * Absorptive cells * Cardiac endothelial cells * Intestinal crypt stem cells of colon * Tuft cells of colon * BEST4+ intestinal epithelial cells * Human choroid plexus epithelial cells In conclusion, ZBTB17 is a transcription factor gene that plays a crucial role in regulating various cellular processes, including immune response, cell cycle progression, and development. Its involvement in multiple signaling pathways, including the UPR and the unfolded protein response-mediated apoptosis (UPRap), highlights its importance in maintaining cellular homeostasis. Further research is needed to fully understand the role of ZBTB17 in immune-related disorders and to explore its potential as a therapeutic target.

Genular Protein ID: 3781790541

Symbol: ZBT17_HUMAN

Name: Zinc finger and BTB domain-containing protein 17

UniProtKB Accession Codes:

Q13105 A0AV07 B4DXB4 B7ZLQ9 F5H411 Q15932 Q5JYB2 Q9NUC9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 20 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 19 PDBsum 19 PIR 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9312026

Title: An alternative pathway for gene regulation by Myc.

PubMed ID: 9312026

DOI: 10.1093/emboj/16.18.5672

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1505991

Title: Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.

PubMed ID: 1505991

DOI: 10.1016/0888-7543(92)90013-i

PubMed ID: 7557990

Title: Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

PubMed ID: 7557990

DOI: 10.1006/geno.1995.1040

PubMed ID: 9308237

Title: Association of Myc with the zinc-finger protein Miz-1 defines a novel pathway for gene regulation by Myc.

PubMed ID: 9308237

DOI: 10.1007/978-3-642-60801-8_14

PubMed ID: 12244100

Title: Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1.

PubMed ID: 12244100

DOI: 10.1074/jbc.m206226200

PubMed ID: 12545156

Title: Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter.

PubMed ID: 12545156

DOI: 10.1038/sj.onc.1206145

PubMed ID: 14739298

Title: A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells.

PubMed ID: 14739298

DOI: 10.1074/jbc.m310437200

PubMed ID: 15095404

Title: Induction of G1 cell cycle arrest and P15INK4b expression by ECRG1 through interaction with Miz-1.

PubMed ID: 15095404

DOI: 10.1002/jcb.20025

PubMed ID: 16142238

Title: BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells.

PubMed ID: 16142238

DOI: 10.1038/ni1245

PubMed ID: 19164764

Title: Gfi-1 represses CDKN2B encoding p15INK4B through interaction with Miz-1.

PubMed ID: 19164764

DOI: 10.1073/pnas.0804863106

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25245946

Title: Two ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stress.

PubMed ID: 25245946

DOI: 10.1093/nar/gku857

PubMed ID: 17880999

Title: A beta-sheet interaction interface directs the tetramerisation of the Miz-1 POZ domain.

PubMed ID: 17880999

DOI: 10.1016/j.jmb.2007.08.026

Sequence Information:

  • Length: 803
  • Mass: 87928
  • Checksum: C159D177C8A2D4A3
  • Sequence:
    • MDFPQHSQHV LEQLNQQRQL GLLCDCTFVV DGVHFKAHKA VLAACSEYFK MLFVDQKDVV 
HLDISNAAGL GQVLEFMYTA KLSLSPENVD DVLAVATFLQ MQDIITACHA LKSLAEPATS 
PGGNAEALAT EGGDKRAKEE KVATSTLSRL EQAGRSTPIG PSRDLKEERG GQAQSAASGA 
EQTEKADAPR EPPPVELKPD PTSGMAAAEA EAALSESSEQ EMEVEPARKG EEEQKEQEEQ 
EEEGAGPAEV KEEGSQLENG EAPEENENEE SAGTDSGQEL GSEARGLRSG TYGDRTESKA 
YGSVIHKCED CGKEFTHTGN FKRHIRIHTG EKPFSCRECS KAFSDPAACK AHEKTHSPLK 
PYGCEECGKS YRLISLLNLH KKRHSGEARY RCEDCGKLFT TSGNLKRHQL VHSGEKPYQC 
DYCGRSFSDP TSKMRHLETH DTDKEHKCPH CDKKFNQVGN LKAHLKIHIA DGPLKCRECG 
KQFTTSGNLK RHLRIHSGEK PYVCIHCQRQ FADPGALQRH VRIHTGEKPC QCVMCGKAFT 
QASSLIAHVR QHTGEKPYVC ERCGKRFVQS SQLANHIRHH DNIRPHKCSV CSKAFVNVGD 
LSKHIIIHTG EKPYLCDKCG RGFNRVDNLR SHVKTVHQGK AGIKILEPEE GSEVSVVTVD 
DMVTLATEAL AATAVTQLTV VPVGAAVTAD ETEVLKAEIS KAVKQVQEED PNTHILYACD 
SCGDKFLDAN SLAQHVRIHT AQALVMFQTD ADFYQQYGPG GTWPAGQVLQ AGELVFRPRD 
GAEGQPALAE TSPTAPECPP PAE

Genular Protein ID: 2447231460

Symbol: Q53EM1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53EM1

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 2 SAM 1 SMART 2 SUPFAM 2

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 803
  • Mass: 87914
  • Checksum: DD28816399E7C0F3
  • Sequence:
    • MDFPQHSQHV LEQLNQQRQL GLLCDCTFVV DGVHFKAHKA VLAACSEYFK MLFVDQKDVV 
HLDISNAAGL GQVLEFMYTA KLSLSPENVD DVLAVATFLQ MQDIITACHA LKSLAEPATS 
PGGNAEALAT EGGDKRAKEE KVATSTLSRL EQAGRSTPIG PSRDLKEERG GQAQSAASGA 
EQTEKADAPR EPPPVELKPD PTSGMAAAEA EAALSESSEQ EMEVEPARKG EEEQKEQEEQ 
EEEGAGPAEV KEEGSQLENG EAPEENENEE SAGTDSGQEL GSEARGLRSG TYGDRTESKA 
YGSVIHKCED CGKEFTHTGN FKRHIRIHTG EKPFSCRECS KAFSDPAACK AHEKTHSPLK 
PYGCEECGKS YRLISLLNLH KKRHSGEARY RCEDCGKLFT TSGNLKRHQL VHSGEKPYQC 
DYCGRSFSDP TSKMRHLETH DTDKEHKCPH CDKKFNQVGN LKAHLKIHIA DGPLKCRECG 
KQFTTSGNLK RHLRIHSGEK PYVCIHCQRQ FADPGALQRH VRIHTGEKPC QCVMCGKAFT 
QASSLIAHVR QHTGEKPYVC ERCGKRFVQS SQLANHIRHH DNIRPHKCSV CSKAFVNVGD 
LSKHIIIHTG EKPYLCDKCG RGFNRVDNLR SHVKTVHQGK AGIKILEPEE GSEVSVVTVD 
DMVTLATEAL AATAVTQLTV VPVGAAVTAD ETEVLKADIS KAVKQVQEED PNTHILYACD 
SCGDKFLDAN SLAQHVRIHT AQALVMFQTD ADFYQQYGPG GTWPAGQVLQ AGELVFRPRD 
GAEGQPALAE TSPTAPECPP PAE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.