Details for: ALMS1

Gene ID: 7840

Symbol: ALMS1

Ensembl ID: ENSG00000116127

Description: ALMS1 centrosome and basal body associated protein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 224.2435
    Cell Significance Index: -34.8800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 138.8169
    Cell Significance Index: -35.2100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 76.8868
    Cell Significance Index: -36.3000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 71.4818
    Cell Significance Index: -29.0400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 30.1966
    Cell Significance Index: -28.8300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 29.1738
    Cell Significance Index: -35.9700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.0951
    Cell Significance Index: -35.0800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.3941
    Cell Significance Index: -31.9300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.1839
    Cell Significance Index: -36.2400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.5254
    Cell Significance Index: -16.4700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 3.3063
    Cell Significance Index: 185.5300
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 2.4432
    Cell Significance Index: 40.2600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.9200
    Cell Significance Index: 385.1600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.5642
    Cell Significance Index: 69.1900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.5404
    Cell Significance Index: 58.3300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.4686
    Cell Significance Index: 291.4500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.2632
    Cell Significance Index: 124.9600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.0857
    Cell Significance Index: 750.8800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.0501
    Cell Significance Index: 70.6100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0419
    Cell Significance Index: 940.7600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9671
    Cell Significance Index: 346.8800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.9027
    Cell Significance Index: 19.3000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.7743
    Cell Significance Index: 47.5900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.6589
    Cell Significance Index: 41.5300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6530
    Cell Significance Index: 106.2100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.6285
    Cell Significance Index: 48.2300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.6084
    Cell Significance Index: 14.5900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5673
    Cell Significance Index: 61.7100
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.5571
    Cell Significance Index: 5.6200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.5466
    Cell Significance Index: 14.0500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.5148
    Cell Significance Index: 14.6900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.4704
    Cell Significance Index: 9.1800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4151
    Cell Significance Index: 11.9600
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.3993
    Cell Significance Index: 4.9500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2960
    Cell Significance Index: 7.4000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2837
    Cell Significance Index: 17.0300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2474
    Cell Significance Index: 5.3600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2097
    Cell Significance Index: 14.5000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1625
    Cell Significance Index: 4.5400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1568
    Cell Significance Index: 295.2000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1546
    Cell Significance Index: 285.1500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1512
    Cell Significance Index: 3.3100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1441
    Cell Significance Index: 2.4700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1290
    Cell Significance Index: 23.2500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1227
    Cell Significance Index: 16.8500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1172
    Cell Significance Index: 180.3600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1160
    Cell Significance Index: 63.3600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1127
    Cell Significance Index: 71.5500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0982
    Cell Significance Index: 3.4500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0927
    Cell Significance Index: 4.2000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0759
    Cell Significance Index: 103.1400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0750
    Cell Significance Index: 34.0200
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 0.0701
    Cell Significance Index: 0.7300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0584
    Cell Significance Index: 3.0400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0519
    Cell Significance Index: 9.8700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0446
    Cell Significance Index: 5.4900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0087
    Cell Significance Index: -3.8600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0299
    Cell Significance Index: -4.3500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0306
    Cell Significance Index: -22.4000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0348
    Cell Significance Index: -5.9500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0354
    Cell Significance Index: -26.2500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0396
    Cell Significance Index: -4.6100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0478
    Cell Significance Index: -36.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0554
    Cell Significance Index: -31.2200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0567
    Cell Significance Index: -2.9500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0634
    Cell Significance Index: -39.6000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1051
    Cell Significance Index: -4.9000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1060
    Cell Significance Index: -30.5000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1252
    Cell Significance Index: -14.7700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1490
    Cell Significance Index: -19.1000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1742
    Cell Significance Index: -36.6900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1853
    Cell Significance Index: -18.9300
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.2165
    Cell Significance Index: -2.7000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2334
    Cell Significance Index: -26.7500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2469
    Cell Significance Index: -25.7100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2480
    Cell Significance Index: -32.0400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2514
    Cell Significance Index: -3.6100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3058
    Cell Significance Index: -8.2000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3100
    Cell Significance Index: -20.0000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3165
    Cell Significance Index: -6.7400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3750
    Cell Significance Index: -12.0100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3784
    Cell Significance Index: -7.8500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3934
    Cell Significance Index: -8.3500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3943
    Cell Significance Index: -31.2300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3959
    Cell Significance Index: -12.6100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3977
    Cell Significance Index: -18.6900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.4027
    Cell Significance Index: -30.0100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4096
    Cell Significance Index: -8.1000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.4171
    Cell Significance Index: -29.5000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4239
    Cell Significance Index: -13.8800
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.4304
    Cell Significance Index: -6.1900
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.4770
    Cell Significance Index: -6.0200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.5176
    Cell Significance Index: -6.1700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5504
    Cell Significance Index: -28.9000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.5524
    Cell Significance Index: -11.0900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5658
    Cell Significance Index: -34.6900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5870
    Cell Significance Index: -15.4400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.6404
    Cell Significance Index: -9.4600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.6748
    Cell Significance Index: -14.5800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6819
    Cell Significance Index: -23.8900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ALMS1 is a centrosome and basal body-associated protein, characterized by its unique structure and localization within the cell. It is involved in various cellular processes, including: 1. Anchoring of basal body to plasma membrane 2. Activation of Aurka by tpx2 3. Regulation of centriole replication 4. Recruitment of mitotic centrosome proteins and complexes 5. Positive regulation of cold-induced thermogenesis **Pathways and Functions:** ALMS1 is involved in multiple cellular pathways, including: 1. **Anchoring of basal body to plasma membrane:** ALMS1 plays a crucial role in anchoring the basal body to the plasma membrane, ensuring proper centrosome and ciliary function. 2. **Aurka activation by tpx2:** ALMS1 interacts with tpx2 to activate Aurka, a kinase involved in centrosome maturation and separation. 3. **Cell cycle regulation:** ALMS1 is involved in regulating the cell cycle, particularly during the G2/M transition, ensuring proper chromosome segregation. 4. **Centriole replication:** ALMS1 regulates centriole replication, ensuring the proper formation of centrosomes and cilia. 5. **Molecular functions:** ALMS1 has been implicated in various molecular functions, including the regulation of cold-induced thermogenesis and the recruitment of mitotic centrosome proteins and complexes. **Significantly Expressed Cells:** ALMS1 is significantly expressed in various cell types, including: 1. **Anterior lens cells** 2. **Lamp5 GABAergic cortical interneurons** 3. **Neurons** 4. **L2/3-6 intratelencephalic projecting glutamatergic neurons** 5. **OFF retinal ganglion cells** 6. **Corticothalamic-projecting glutamatergic cortical neurons** 7. **sst GABAergic cortical interneurons** 8. **Astrocytes of the cerebral cortex** 9. **Ciliated cells** 10. **pvalb GABAergic cortical interneurons** **Clinical Significance:** The dysregulation of ALMS1 has been implicated in various diseases, including: 1. **Alstrom syndrome:** A rare genetic disorder characterized by progressive retinal degeneration, obesity, and diabetes. 2. **Ciliopathies:** A group of disorders caused by defects in cilia function, leading to various clinical manifestations. 3. **Neurological disorders:** ALMS1 has been implicated in various neurological disorders, including neurodegenerative diseases and cognitive impairments. In conclusion, ALMS1 is a multifunctional protein that plays a crucial role in various cellular processes, including centrosome and basal body function, cell cycle regulation, and molecular functions. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the functions and clinical significance of ALMS1.

Genular Protein ID: 652807335

Symbol: ALMS1_HUMAN

Name: Alstrom syndrome protein 1

UniProtKB Accession Codes:

Q8TCU4 A0A087WZY3 Q53S05 Q580Q8 Q86VP9 Q9Y4G4

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 CarbonylDB 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 1 ExpressionAtlas 1 GO 9 GeneCards 1 GeneReviews 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 7 RefSeq 1 STRING 1 SignaLink 1 TreeFam 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11941370

Title: Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alstrom syndrome.

PubMed ID: 11941370

DOI: 10.1038/ng874

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11941369

Title: Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome.

PubMed ID: 11941369

DOI: 10.1038/ng867

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15855349

Title: Subcellular localization of ALMS1 supports involvement of centrosome and basal body dysfunction in the pathogenesis of obesity, insulin resistance, and type 2 diabetes.

PubMed ID: 15855349

DOI: 10.2337/diabetes.54.5.1581

PubMed ID: 17954613

Title: Cep164, a novel centriole appendage protein required for primary cilium formation.

PubMed ID: 17954613

DOI: 10.1083/jcb.200707181

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20844083

Title: Centriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731.

PubMed ID: 20844083

DOI: 10.1091/mbc.e10-03-0246

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 4168
  • Mass: 461062
  • Checksum: 4A0D55F656316277
  • Sequence:
    • MEPEDLPWPG ELEEEEEEEE EEEEEEEEAA AAAAANVDDV VVVEEVEEEA GRELDSDSHY 
GPQHLESIDD EEDEEAKAWL QAHPGRILPP LSPPQHRYSE GERTSLEKIV PLTCHVWQQI 
VYQGNSRTQI SDTNVVCLET TAQRGSGDDQ KTESWHCLPQ EMDSSQTLDT SQTRFNVRTE 
DTEVTDFPSL EEGILTQSEN QVKEPNRDLF CSPLLVIQDS FASPDLPLLT CLTQDQEFAP 
DSLFHQSELS FAPLRGIPDK SEDTEWSSRP SEVSEALFQA TAEVASDLAS SRFSVSQHPL 
IGSTAVGSQC PFLPSEQGNN EETISSVDEL KIPKDCDRYD DLCSYMSWKT RKDTQWPENN 
LADKDQVSVA TSFDITDENI ATKRSDHFDA ARSYGQYWTQ EDSSKQAETY LTKGLQGKVE 
SDVITLDGLN ENAVVCSERV AELQRKPTRE SEYHSSDLRM LRMSPDTVPK APKHLKAGDT 
SKGGIAKVTQ SNLKSGITTT PVDSDIGSHL SLSLEDLSQL AVSSPLETTT GQHTDTLNQK 
TLADTHLTEE TLKVTAIPEP ADQKTATPTV LSSSHSHRGK PSIFYQQGLP DSHLTEEALK 
VSAAPGLADQ TTGMSTLTST SYSHREKPGT FYQQELPESN LTEEPLEVSA APGPVEQKTG 
IPTVSSTSHS HVEDLLFFYR QTLPDGHLTD QALKVSAVSG PADQKTGTAT VLSTPHSHRE 
KPGIFYQQEF ADSHQTEETL TKVSATPGPA DQKTEIPAVQ SSSYSQREKP SILYPQDLAD 
SHLPEEGLKV SAVAGPADQK TGLPTVPSSA YSHREKLLVF YQQALLDSHL PEEALKVSAV 
SGPADGKTGT PAVTSTSSAS SSLGEKPSAF YQQTLPNSHL TEEALKVSIV PGPGDQKTGI 
PSAPSSFYSH REKPIIFSQQ TLPDFLFPEE ALKVSAVSVL AAQKTGTPTV SSNSHSHSEK 
SSVFYQQELP DSDLPRESLK MSAIPGLTDQ KTVPTPTVPS GSFSHREKPS IFYQQEWPDS 
YATEKALKVS TGPGPADQKT EIPAVQSSSY PQREKPSVLY PQVLSDSHLP EESLKVSAFP 
GPADQMTDTP AVPSTFYSQR EKPGIFYQQT LPESHLPKEA LKISVAPGLA DQKTGTPTVT 
STSYSQHREK PSIFHQQALP GTHIPEEAQK VSAVTGPGNQ KTWIPRVLST FYSQREKPGI 
FYQQTLPGSH IPEEAQKVSP VLGPADQKTG TPTPTSASYS HTEKPGIFYQ QVLPDNHPTE 
EALKISVASE PVDQTTGTPA VTSTSYSQYR EKPSIFYQQS LPSSHLTEEA KNVSAVPGPA 
DQKTVIPILP STFYSHTEKP GVFYQQVLPH SHPTEEALKI SVASEPVDQT TGTPTVTSTS 
YSQHTEKPSI FYQQSLPGSH LTEEAKNVSA VPGPGDRKTG IPTLPSTFYS HTEKPGSFYQ 
QVLPHSHLPE EALEVSVAPG PVDQTIGTPT VTSPSSSFGE KPIVIYKQAF PEGHLPEESL 
KVSVAPGPVG QTTGAPTITS PSYSQHRAKS GSFYQLALLG SQIPEEALRV SSAPGPADQT 
TGIPTITSTS YSFGEKPIVN YKQAFPDGHL PEEALKVSIV SGPTEKKTDI PAGPLGSSAL 
GEKPITFYRQ ALLDSPLNKE VVKVSAAPGP ADQKTETLPV HSTSYSNRGK PVIFYQQTLS 
DSHLPEEALK VPPVPGPDAQ KTETPSVSSS LYSYREKPIV FYQQALPDSE LTQEALKVSA 
VPQPADQKTG LSTVTSSFYS HTEKPNISYQ QELPDSHLTE EALKVSNVPG PADQKTGVST 
VTSTSYSHRE KPIVSYQREL PHFTEAGLKI LRVPGPADQK TGINILPSNS YPQREHSVIS 
YEQELPDLTE VTLKAIGVPG PADQKTGIQI ASSSSYSNRE KASIFHQQEL PDVTEEALNV 
FVVPGQGDRK TEIPTVPLSY YSRREKPSVI SQQELPDSHL TEEALKVSPV SIPAEQKTGI 
PIGLSSSYSH SHKEKLKIST VHIPDDQKTE FPAATLSSYS QIEKPKISTV IGPNDQKTPS 
QTAFHSSYSQ TVKPNILFQQ QLPDRDQSKG ILKISAVPEL TDVNTGKPVS LSSSYFHREK 
SNIFSPQELP GSHVTEDVLK VSTIPGPAGQ KTVLPTALPS SFSHREKPDI FYQKDLPDRH 
LTEDALKISS ALGQADQITG LQTVPSGTYS HGENHKLVSE HVQRLIDNLN SSDSSVSSNN 
VLLNSQADDR VVINKPESAG FRDVGSEEIQ DAENSAKTLK EIRTLLMEAE NMALKRCNFP 
APLARFRDIS DISFIQSKKV VCFKEPSSTG VSNGDLLHRQ PFTEESPSSR CIQKDIGTQT 
NLKCRRGIEN WEFISSTTVR SPLQEAESKV SMALEETLRQ YQAAKSVMRS EPEGCSGTIG 
NKIIIPMMTV IKSDSSSDAS DGNGSCSWDS NLPESLESVS DVLLNFFPYV SPKTSITDSR 
EEEGVSESED GGGSSVDSLA AHVKNLLQCE SSLNHAKEIL RNAEEEESRV RAHAWNMKFN 
LAHDCGYSIS ELNEDDRRKV EEIKAELFGH GRTTDLSKGL QSPRGMGCKP EAVCSHIIIE 
SHEKGCFRTL TSEHPQLDRH PCAFRSAGPS EMTRGRQNPS SCRAKHVNLS ASLDQNNSHF 
KVWNSLQLKS HSPFQNFIPD EFKISKGLRM PFDEKMDPWL SELVEPAFVP PKEVDFHSSS 
QMPSPEPMKK FTTSITFSSH RHSKCISNSS VVKVGVTEGS QCTGASVGVF NSHFTEEQNP 
PRDLKQKTSS PSSFKMHSNS QDKEVTILAE GRRQSQKLPV DFERSFQEEK PLERSDFTGS 
HSEPSTRANC SNFKEIQISD NHTLISMGRP SSTLGVNRSS SRLGVKEKNV TITPDLPSCI 
FLEQRELFEQ SKAPRADDHV RKHHSPSPQH QDYVAPDLPS CIFLEQRELF EQCKAPYVDH 
QMRENHSPLP QGQDSIASDL PSPISLEQCQ SKAPGVDDQM NKHHFPLPQG QDCVVEKNNQ 
HKPKSHISNI NVEAKFNTVV SQSAPNHCTL AASASTPPSN RKALSCVHIT LCPKTSSKLD 
SGTLDERFHS LDAASKARMN SEFNFDLHTV SSRSLEPTSK LLTSKPVAQD QESLGFLGPK 
SSLDFQVVQP SLPDSNTITQ DLKTIPSQNS QIVTSRQIQV NISDFEGHSN PEGTPVFADR 
LPEKMKTPLS AFSEKLSSDA VTQITTESPE KTLFSSEIFI NAEDRGHEII EPGNQKLRKA 
PVKFASSSSV QQVTFSRGTD GQPLLLPYKP SGSTKMYYVP QLRQIPPSPD SKSDTTVESS 
HSGSNDAIAP DFPAQVLGTR DDDLSATVNI KHKEGIYSKR VVTKASLPVG EKPLQNENAD 
ASVQVLITGD ENLSDKKQQE IHSTRAVTEA AQAKEKESLQ KDTADSSAAA AAEHSAQVGD 
PEMKNLPDTK AITQKEEIHR KKTVPEEAWP NNKESLQINI EESECHSEFE NTTRSVFRSA 
KFYIHHPVHL PSDQDICHES LGKSVFMRHS WKDFFQHHPD KHREHMCLPL PYQNMDKTKT 
DYTRIKSLSI NVNLGNKEVM DTTKSQVRDY PKHNGQISDP QRDQKVTPEQ TTQHTVSLNE 
LWNKYRERQR QQRQPELGDR KELSLVDRLD RLAKILQNPI THSLQVSEST HDDSRGERSV 
KEWSGRQQQR NKLQKKKRFK SLEKSHKNTG ELKKSKVLSH HRAGRSNQIK IEQIKFDKYI 
LSKQPGFNYI SNTSSDCRPS EESELLTDTT TNILSGTTST VESDILTQTD REVALHERSS 
SVSTIDTARL IQAFGHERVC LSPRRIKLYS SITNQQRRYL EKRSKHSKKV LNTGHPLVTS 
EHTRRRHIQV ANHVISSDSI SSSASSFLSS NSTFCNKQNV HMLNKGIQAG NLEIVNGAKK 
HTRDVGITFP TPSSSEAKLE ENSDVTSWSE EKREEKMLFT GYPEDRKLKK NKKNSHEGVS 
WFVPVENVES RSKKENVPNT CGPGISWFEP ITKTRPWREP LREQNCQGQH LDGRGYLAGP 
GREAGRDLLR PFVRATLQES LQFHRPDFIS RSGERIKRLK LIVQERKLQS MLQTERDALF 
NIDRERQGHQ NRMCPLPKRV FLAIQKNKPI SKKEMIQRSK RIYEQLPEVQ KKREEEKRKS 
EYKSYRLRAQ LYKKRVTNQL LGRKVPWD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.