Details for: FZD5

Gene ID: 7855

Symbol: FZD5

Ensembl ID: ENSG00000163251

Description: frizzled class receptor 5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 67.2473
    Cell Significance Index: -10.4600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 47.8230
    Cell Significance Index: -12.1300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 25.8407
    Cell Significance Index: -12.2000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 9.4245
    Cell Significance Index: -11.6200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.5766
    Cell Significance Index: -12.2600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.0664
    Cell Significance Index: -12.1000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.7334
    Cell Significance Index: 444.5700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.4282
    Cell Significance Index: 69.9600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.2924
    Cell Significance Index: 103.9100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.0730
    Cell Significance Index: 44.9100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.9888
    Cell Significance Index: 29.8000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.7408
    Cell Significance Index: 189.3500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.0498
    Cell Significance Index: 58.9100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.9428
    Cell Significance Index: 25.2600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.7660
    Cell Significance Index: 15.8900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.7353
    Cell Significance Index: 15.6600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6827
    Cell Significance Index: 67.5300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5883
    Cell Significance Index: 116.7500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.5834
    Cell Significance Index: 7.9600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5627
    Cell Significance Index: 29.2300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4022
    Cell Significance Index: 363.1500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.3022
    Cell Significance Index: 9.6800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2710
    Cell Significance Index: 148.0000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2470
    Cell Significance Index: 42.1800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2419
    Cell Significance Index: 8.5000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2186
    Cell Significance Index: 5.9500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2125
    Cell Significance Index: 26.1300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.2118
    Cell Significance Index: 24.1800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2116
    Cell Significance Index: 27.1300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1849
    Cell Significance Index: 33.3400
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.1826
    Cell Significance Index: 1.9400
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 0.1693
    Cell Significance Index: 1.8400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1295
    Cell Significance Index: 6.0400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1123
    Cell Significance Index: 7.9400
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.1053
    Cell Significance Index: 1.0900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.0344
    Cell Significance Index: 0.5800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0288
    Cell Significance Index: 5.4900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0203
    Cell Significance Index: 15.3600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0169
    Cell Significance Index: 7.4700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0026
    Cell Significance Index: -4.9800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0030
    Cell Significance Index: -2.2200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0034
    Cell Significance Index: -2.1300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0036
    Cell Significance Index: -1.0400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0041
    Cell Significance Index: -0.8200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0050
    Cell Significance Index: -2.8100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0081
    Cell Significance Index: -5.6000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0088
    Cell Significance Index: -16.2800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0095
    Cell Significance Index: -14.6400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0100
    Cell Significance Index: -7.3100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0119
    Cell Significance Index: -16.1500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0121
    Cell Significance Index: -0.1300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0123
    Cell Significance Index: -7.7900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0147
    Cell Significance Index: -1.6800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0212
    Cell Significance Index: -7.6200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0266
    Cell Significance Index: -5.6100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0267
    Cell Significance Index: -12.1100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0282
    Cell Significance Index: -2.8800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0365
    Cell Significance Index: -1.0200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0422
    Cell Significance Index: -1.0600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0430
    Cell Significance Index: -2.7100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0465
    Cell Significance Index: -6.3800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0503
    Cell Significance Index: -0.4100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0526
    Cell Significance Index: -6.1300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0565
    Cell Significance Index: -7.3000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0567
    Cell Significance Index: -8.2400
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.0754
    Cell Significance Index: -0.5800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0845
    Cell Significance Index: -6.4900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0963
    Cell Significance Index: -11.3600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1071
    Cell Significance Index: -5.0400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1073
    Cell Significance Index: -8.0000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.1077
    Cell Significance Index: -1.5900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1174
    Cell Significance Index: -12.2200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1303
    Cell Significance Index: -10.3200
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.1328
    Cell Significance Index: -0.9000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1394
    Cell Significance Index: -8.5700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1398
    Cell Significance Index: -7.0700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1731
    Cell Significance Index: -11.1700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1801
    Cell Significance Index: -12.1100
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.1828
    Cell Significance Index: -2.9000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1948
    Cell Significance Index: -11.9500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2042
    Cell Significance Index: -5.2500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2128
    Cell Significance Index: -1.9600
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.2128
    Cell Significance Index: -1.3200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2139
    Cell Significance Index: -11.2300
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.2322
    Cell Significance Index: -3.3000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2333
    Cell Significance Index: -10.3200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2435
    Cell Significance Index: -8.4600
  • Cell Name: colon endothelial cell (CL1001572)
    Fold Change: -0.2489
    Cell Significance Index: -0.1900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.2542
    Cell Significance Index: -10.4200
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: -0.2624
    Cell Significance Index: -1.2500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2662
    Cell Significance Index: -10.0800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2787
    Cell Significance Index: -7.9900
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.2852
    Cell Significance Index: -4.0100
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.2958
    Cell Significance Index: -2.1500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3010
    Cell Significance Index: -11.0500
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.3028
    Cell Significance Index: -2.0100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.3158
    Cell Significance Index: -13.7300
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.3246
    Cell Significance Index: -1.7000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3326
    Cell Significance Index: -11.6500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** FZD5 is a transmembrane protein with 11 extracellular domains, which are crucial for ligand binding and signaling. It is a member of the Frizzled family of receptors, which are characterized by the presence of a conserved seven-transmembrane domain structure. FZD5 is highly expressed in various tissues, including the pancreas, colon, kidney, and brain, where it plays a crucial role in development and tissue homeostasis. **Pathways and Functions:** FZD5 is a key receptor in the Wnt signaling pathway, which is a complex network of signaling molecules that regulate various cellular processes, including cell fate determination, proliferation, and differentiation. FZD5 is involved in both canonical (β-catenin-dependent) and non-canonical (β-catenin-independent) Wnt signaling pathways. The canonical pathway is involved in the regulation of cell fate determination, while the non-canonical pathway is involved in the regulation of cell migration and axon guidance. In addition to Wnt signaling, FZD5 is also involved in other signaling pathways, including the Ca2+ pathway, the G protein-coupled receptor (GPCR) signaling pathway, and the MAPK/ERK pathway. FZD5 has been shown to regulate various cellular processes, including cell proliferation, differentiation, migration, and apoptosis. **Clinical Significance:** FZD5 has been implicated in various diseases, including cancer, neurological disorders, and metabolic disorders. In cancer, FZD5 has been shown to be overexpressed in several types of cancer, including colorectal, breast, and lung cancer, where it may contribute to tumorigenesis and metastasis. In neurological disorders, FZD5 has been implicated in the regulation of neuronal development and function, where it may contribute to the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. In metabolic disorders, FZD5 has been shown to regulate glucose metabolism and insulin signaling, where it may contribute to the development of type 2 diabetes. FZD5 has also been implicated in the regulation of inflammation and immune responses, where it may contribute to the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. **Signaling Mechanisms:** FZD5 signaling involves the binding of Wnt proteins to the extracellular domains of FZD5, which triggers a series of downstream signaling events. The binding of Wnt proteins to FZD5 activates the G protein-coupled receptor (GPCR) signaling pathway, which involves the activation of G proteins, which in turn activate downstream effectors, such as adenylyl cyclase and phospholipase C. The activation of these effectors leads to the production of second messengers, such as cAMP and IP3, which regulate various cellular processes, including cell proliferation, differentiation, and migration. **Regulation of FZD5:** FZD5 is regulated by several mechanisms, including ubiquitination, which involves the tagging of FZD5 with ubiquitin protein ligase, leading to its degradation. FZD5 is also regulated by the Wnt/β-catenin signaling pathway, where the binding of Wnt proteins to FZD5 activates the canonical pathway, leading to the degradation of β-catenin and the inhibition of FZD5 signaling. **Conclusion:** In conclusion, FZD5 is a key player in Wnt signaling pathways and beyond. Its involvement in various cellular processes, including development, differentiation, and disease, highlights its importance in understanding human health and disease. Further research is needed to fully elucidate the mechanisms of FZD5 signaling and regulation, as well as its role in various diseases.

Genular Protein ID: 2407616758

Symbol: FZD5_HUMAN

Name: Frizzled-5

UniProtKB Accession Codes:

Q13467 A8K2X1 B2RCZ1 Q53R22

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 1 GO 49 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 6 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 7 RefSeq 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8626800

Title: A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.

PubMed ID: 8626800

DOI: 10.1074/jbc.271.8.4468

PubMed ID: 11408929

Title: Molecular cloning and characterization of human Frizzled-5 gene on chromosome 2q33.3-q34 region.

PubMed ID: 11408929

DOI: 10.3892/ijo.19.1.105

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 9707618

Title: A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.

PubMed ID: 9707618

DOI: 10.1073/pnas.95.17.10164

PubMed ID: 9054360

Title: A member of the Frizzled protein family mediating axis induction by Wnt-5A.

PubMed ID: 9054360

DOI: 10.1126/science.275.5306.1652

PubMed ID: 10097073

Title: Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein.

PubMed ID: 10097073

DOI: 10.1073/pnas.96.7.3546

PubMed ID: 12490564

Title: Wnt2b controls retinal cell differentiation at the ciliary marginal zone.

PubMed ID: 12490564

DOI: 10.1242/dev.00244

PubMed ID: 18230341

Title: Wnt7a interaction with Fzd5 and detection of signaling activation using a split eGFP.

PubMed ID: 18230341

DOI: 10.1016/j.bbrc.2008.01.088

PubMed ID: 20530549

Title: Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis.

PubMed ID: 20530549

DOI: 10.1242/dev.046722

PubMed ID: 22575959

Title: ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.

PubMed ID: 22575959

DOI: 10.1038/nature11019

PubMed ID: 22895187

Title: Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.

PubMed ID: 22895187

DOI: 10.1038/nature11308

PubMed ID: 28377511

Title: Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding.

PubMed ID: 28377511

DOI: 10.1073/pnas.1618293114

PubMed ID: 26908622

Title: A secreted WNT-ligand-binding domain of FZD5 generated by a frameshift mutation causes autosomal dominant coloboma.

PubMed ID: 26908622

DOI: 10.1093/hmg/ddw020

PubMed ID: 32737437

Title: Confirmation of FZD5 implication in a cohort of 50 patients with ocular coloboma.

PubMed ID: 32737437

DOI: 10.1038/s41431-020-0695-8

PubMed ID: 33633439

Title: Confirming and expanding the phenotypes of FZD5 variants: Coloboma, inferior chorioretinal hypoplasia, and high myopia.

PubMed ID: 33633439

Sequence Information:

  • Length: 585
  • Mass: 64507
  • Checksum: AC3AB2CD912C1B0A
  • Sequence:
    • MARPDPSAPP SLLLLLLAQL VGRAAAASKA PVCQEITVPM CRGIGYNLTH MPNQFNHDTQ 
DEAGLEVHQF WPLVEIQCSP DLRFFLCSMY TPICLPDYHK PLPPCRSVCE RAKAGCSPLM 
RQYGFAWPER MSCDRLPVLG RDAEVLCMDY NRSEATTAPP RPFPAKPTLP GPPGAPASGG 
ECPAGGPFVC KCREPFVPIL KESHPLYNKV RTGQVPNCAV PCYQPSFSAD ERTFATFWIG 
LWSVLCFIST STTVATFLID MERFRYPERP IIFLSACYLC VSLGFLVRLV VGHASVACSR 
EHNHIHYETT GPALCTIVFL LVYFFGMASS IWWVILSLTW FLAAGMKWGN EAIAGYAQYF 
HLAAWLIPSV KSITALALSS VDGDPVAGIC YVGNQNLNSL RGFVLGPLVL YLLVGTLFLL 
AGFVSLFRIR SVIKQGGTKT DKLEKLMIRI GIFTLLYTVP ASIVVACYLY EQHYRESWEA 
ALTCACPGHD TGQPRAKPEY WVLMLKYFMC LVVGITSGVW IWSGKTVESW RRFTSRCCCR 
PRRGHKSGGA MAAGDYPEAS AALTGRTGPP GPAATYHKQV SLSHV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.