Details for: FBXO31
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 131.7302
Cell Significance Index: -20.4900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 81.5318
Cell Significance Index: -20.6800 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 32.6964
Cell Significance Index: -21.9400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 16.9836
Cell Significance Index: -20.9400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 7.7272
Cell Significance Index: -20.7000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 5.3243
Cell Significance Index: -21.0100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.4012
Cell Significance Index: 476.5300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 2.3209
Cell Significance Index: 441.6900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.4575
Cell Significance Index: 144.1800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.2169
Cell Significance Index: 244.1100 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.1030
Cell Significance Index: 18.5800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.8226
Cell Significance Index: 89.4800 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.7817
Cell Significance Index: 46.9300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.7744
Cell Significance Index: 125.9500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.6949
Cell Significance Index: 20.0200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.5948
Cell Significance Index: 15.2900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.5937
Cell Significance Index: 212.9400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.5693
Cell Significance Index: 15.2600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.5486
Cell Significance Index: 42.1000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5394
Cell Significance Index: 24.4500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.5125
Cell Significance Index: 11.1000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.5039
Cell Significance Index: 12.6000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.4002
Cell Significance Index: 17.7000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3935
Cell Significance Index: 355.3100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.3605
Cell Significance Index: 13.6500 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.3540
Cell Significance Index: 4.8300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.2661
Cell Significance Index: 184.0300 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2592
Cell Significance Index: 17.9300 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.2481
Cell Significance Index: 3.9800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.2454
Cell Significance Index: 28.6000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.2184
Cell Significance Index: 14.6900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1988
Cell Significance Index: 35.8400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1267
Cell Significance Index: 17.4000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1220
Cell Significance Index: 3.4100 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.1184
Cell Significance Index: 2.8900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1171
Cell Significance Index: 4.1200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1133
Cell Significance Index: 213.3500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.1128
Cell Significance Index: 13.8800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1075
Cell Significance Index: 6.6100 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.1069
Cell Significance Index: 2.3400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1010
Cell Significance Index: 44.6500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0989
Cell Significance Index: 4.6100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0977
Cell Significance Index: 6.1600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0884
Cell Significance Index: 48.3000 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.0843
Cell Significance Index: 1.4900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0843
Cell Significance Index: 4.7300 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.0728
Cell Significance Index: 1.4200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0493
Cell Significance Index: 0.8500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0486
Cell Significance Index: 22.0800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0223
Cell Significance Index: 34.3400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0178
Cell Significance Index: 0.3800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0145
Cell Significance Index: 26.7300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0141
Cell Significance Index: 8.9300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0124
Cell Significance Index: 2.1100 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.0017
Cell Significance Index: -0.0200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0027
Cell Significance Index: -3.6100 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.0080
Cell Significance Index: -0.1200 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0165
Cell Significance Index: -2.1200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0173
Cell Significance Index: -2.5200 - Cell Name: myometrial cell (CL0002366)
Fold Change: -0.0200
Cell Significance Index: -0.2300 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0206
Cell Significance Index: -0.5500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0224
Cell Significance Index: -16.4200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0233
Cell Significance Index: -17.2400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0253
Cell Significance Index: -19.1600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0341
Cell Significance Index: -19.2500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0372
Cell Significance Index: -23.2100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0576
Cell Significance Index: -16.5700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.0656
Cell Significance Index: -1.8800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0718
Cell Significance Index: -7.3300 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.0718
Cell Significance Index: -1.0600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0752
Cell Significance Index: -9.7200 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0782
Cell Significance Index: -3.9500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0846
Cell Significance Index: -9.9800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0999
Cell Significance Index: -5.1900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1016
Cell Significance Index: -11.6400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.1038
Cell Significance Index: -2.4900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1066
Cell Significance Index: -22.4600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1071
Cell Significance Index: -11.1500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1421
Cell Significance Index: -10.0500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1458
Cell Significance Index: -10.8700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1626
Cell Significance Index: -10.4900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1626
Cell Significance Index: -7.6400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1854
Cell Significance Index: -9.7400 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1861
Cell Significance Index: -6.8300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1870
Cell Significance Index: -5.0900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2078
Cell Significance Index: -5.9300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2343
Cell Significance Index: -18.5600 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: -0.2542
Cell Significance Index: -3.5700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.2573
Cell Significance Index: -5.4600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2682
Cell Significance Index: -7.0500 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.2750
Cell Significance Index: -5.5200 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.2760
Cell Significance Index: -3.9700 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.2764
Cell Significance Index: -4.0800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2786
Cell Significance Index: -17.0800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.2886
Cell Significance Index: -10.0300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2962
Cell Significance Index: -4.9600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3080
Cell Significance Index: -9.8100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3219
Cell Significance Index: -10.3100 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.3350
Cell Significance Index: -5.6400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3540
Cell Significance Index: -11.5900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 308263760
Symbol: FBX31_HUMAN
Name: F-box only protein 31
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15520277
Title: Systematic analysis and nomenclature of mammalian F-box proteins.
PubMed ID: 15520277
DOI: 10.1101/gad.1255304
PubMed ID: 15498874
Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.
PubMed ID: 15498874
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16357137
Title: FBXO31 is the chromosome 16q24.3 senescence gene, a candidate breast tumor suppressor, and a component of an SCF complex.
PubMed ID: 16357137
PubMed ID: 19412162
Title: F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage.
PubMed ID: 19412162
DOI: 10.1038/nature08011
PubMed ID: 24623383
Title: Truncation of the E3 ubiquitin ligase component FBXO31 causes non-syndromic autosomal recessive intellectual disability in a Pakistani family.
PubMed ID: 24623383
Sequence Information:
- Length: 539
- Mass: 60664
- Checksum: E833D63A361E7381
- Sequence:
MAVCARLCGV GPSRGCRRRQ QRRGPAETAA ADSEPDTDPE EERIEASAGV GGGLCAGPSP PPPRCSLLEL PPELLVEIFA SLPGTDLPSL AQVCTKFRRI LHTDTIWRRR CREEYGVCEN LRKLEITGVS CRDVYAKLLH RYRHILGLWQ PDIGPYGGLL NVVVDGLFII GWMYLPPHDP HVDDPMRFKP LFRIHLMERK AATVECMYGH KGPHHGHIQI VKKDEFSTKC NQTDHHRMSG GRQEEFRTWL REEWGRTLED IFHEHMQELI LMKFIYTSQY DNCLTYRRIY LPPSRPDDLI KPGLFKGTYG SHGLEIVMLS FHGRRARGTK ITGDPNIPAG QQTVEIDLRH RIQLPDLENQ RNFNELSRIV LEVRERVRQE QQEGGHEAGE GRGRQGPRES QPSPAQPRAE APSKGPDGTP GEDGGEPGDA VAAAEQPAQC GQGQPFVLPV GVSSRNEDYP RTCRMCFYGT GLIAGHGFTS PERTPGVFIL FDEDRFGFVW LELKSFSLYS RVQATFRNAD APSPQAFDEM LKNIQSLTS
Genular Protein ID: 2974411518
Symbol: A0A0C4DGU8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
Sequence Information:
- Length: 367
- Mass: 41735
- Checksum: 354A3698760A2FBE
- Sequence:
MYLPPHDPHV DDPMRFKPLF RIHLMERKAA TVECMYGHKG PHHGHIQIVK KDEFSTKCNQ TDHHRMSGGR QEEFRTWLRE EWGRTLEDIF HEHMQELILM KFIYTSQYDN CLTYRRIYLP PSRPDDLIKP GLFKGTYGSH GLEIVMLSFH GRRARGTKIT GDPNIPAGQQ TVEIDLRHRI QLPDLENQRN FNELSRIVLE VRERVRQEQQ EGGHEAGEGR GRQGPRESQP SPAQPRAEAP SKGPDGTPGE DGGEPGDAVA AAEQPAQCGQ GQPFVLPVGV SSRNEDYPRT CRMCFYGTGL IAGHGFTSPE RTPGVFILFD EDRFGFVWLE LKSFSLYSRV QATFRNADAP SPQAFDEMLK NIQSLTS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.