Details for: RBM10

Gene ID: 8241

Symbol: RBM10

Ensembl ID: ENSG00000182872

Description: RNA binding motif protein 10

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 169.7898
    Cell Significance Index: -26.4100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 100.2589
    Cell Significance Index: -25.4300
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 76.3932
    Cell Significance Index: -31.4700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 67.5672
    Cell Significance Index: -31.9000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 63.3835
    Cell Significance Index: -25.7500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 27.1539
    Cell Significance Index: -25.9300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 23.9100
    Cell Significance Index: -29.4800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 10.7191
    Cell Significance Index: -28.7200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.6482
    Cell Significance Index: -30.1800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.5195
    Cell Significance Index: -12.0800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.6817
    Cell Significance Index: 26.9800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.1333
    Cell Significance Index: 123.2700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1137
    Cell Significance Index: 181.1300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9191
    Cell Significance Index: 55.1800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.8933
    Cell Significance Index: 179.1900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7137
    Cell Significance Index: 141.6400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6378
    Cell Significance Index: 18.3800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.6170
    Cell Significance Index: 47.3500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5556
    Cell Significance Index: 38.4300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.5549
    Cell Significance Index: 28.9100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4453
    Cell Significance Index: 159.7400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4376
    Cell Significance Index: 9.4800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.4147
    Cell Significance Index: 10.6600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3801
    Cell Significance Index: 72.3300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3675
    Cell Significance Index: 10.2700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3507
    Cell Significance Index: 18.2200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3503
    Cell Significance Index: 34.6600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3490
    Cell Significance Index: 47.9300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3251
    Cell Significance Index: 177.5600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.2959
    Cell Significance Index: 18.1900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2905
    Cell Significance Index: 35.7300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2874
    Cell Significance Index: 16.1300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2825
    Cell Significance Index: 33.3100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2753
    Cell Significance Index: 17.7600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2297
    Cell Significance Index: 158.8900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2248
    Cell Significance Index: 6.1200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2243
    Cell Significance Index: 40.4400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.1872
    Cell Significance Index: 19.1200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1806
    Cell Significance Index: 8.4200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1455
    Cell Significance Index: 18.6500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1342
    Cell Significance Index: 4.7200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.1342
    Cell Significance Index: 3.5900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1189
    Cell Significance Index: 52.5500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1178
    Cell Significance Index: 5.5400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1165
    Cell Significance Index: 7.3400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0958
    Cell Significance Index: 3.3300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0864
    Cell Significance Index: 5.8100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0553
    Cell Significance Index: 9.4500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0331
    Cell Significance Index: 4.2700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0211
    Cell Significance Index: 0.4500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0198
    Cell Significance Index: 37.3300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0194
    Cell Significance Index: 17.5100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0109
    Cell Significance Index: 1.2500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0034
    Cell Significance Index: -6.3400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0035
    Cell Significance Index: -1.6100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0051
    Cell Significance Index: -7.9200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0051
    Cell Significance Index: -6.9100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0071
    Cell Significance Index: -0.1900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0113
    Cell Significance Index: -7.1900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0158
    Cell Significance Index: -0.4200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0202
    Cell Significance Index: -14.8100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0230
    Cell Significance Index: -17.4100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0323
    Cell Significance Index: -23.9200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0496
    Cell Significance Index: -27.9800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0506
    Cell Significance Index: -1.4500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0529
    Cell Significance Index: -2.4000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0545
    Cell Significance Index: -34.0400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0729
    Cell Significance Index: -5.4300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0744
    Cell Significance Index: -1.6300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0881
    Cell Significance Index: -4.6300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0886
    Cell Significance Index: -3.9200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0928
    Cell Significance Index: -1.5900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1067
    Cell Significance Index: -15.5100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1072
    Cell Significance Index: -30.8400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1434
    Cell Significance Index: -5.4300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1586
    Cell Significance Index: -33.4200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1842
    Cell Significance Index: -21.4700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1923
    Cell Significance Index: -13.6000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2131
    Cell Significance Index: -5.1100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2627
    Cell Significance Index: -27.3500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2698
    Cell Significance Index: -8.6400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2718
    Cell Significance Index: -5.6900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2724
    Cell Significance Index: -6.8100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3206
    Cell Significance Index: -25.3900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3280
    Cell Significance Index: -8.3800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3319
    Cell Significance Index: -9.4700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3489
    Cell Significance Index: -8.0600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3569
    Cell Significance Index: -4.8700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3597
    Cell Significance Index: -5.3100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.4018
    Cell Significance Index: -6.0200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.4254
    Cell Significance Index: -7.1200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4544
    Cell Significance Index: -27.8600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.4697
    Cell Significance Index: -13.8000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.5012
    Cell Significance Index: -5.9800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.5201
    Cell Significance Index: -10.1500
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.5783
    Cell Significance Index: -9.5300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6104
    Cell Significance Index: -19.4400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.6222
    Cell Significance Index: -20.3700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.6279
    Cell Significance Index: -6.5000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.6361
    Cell Significance Index: -13.5000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** RBM10 is a non-coding RNA-binding protein that belongs to the RNA-binding motif (RBM) family. It is characterized by its ability to bind to specific RNA sequences, thereby regulating their stability and processing. RBM10 is primarily expressed in cells of the nervous system, cardiovascular system, and reproductive system. Its expression is tissue-specific, with notable presence in cardiac muscle cells, choroid plexus epithelial cells, and germ cells. RBM10 is also involved in the regulation of vascular smooth muscle cell proliferation and apoptosis, highlighting its potential role in cardiovascular diseases. **Pathways and Functions** RBM10 is involved in several key pathways, including: 1. **3'-UTR-mediated mRNA stabilization**: RBM10 binds to the 3'-untranslated region (UTR) of target mRNAs, stabilizing them and promoting their translation. 2. **Negative regulation of mRNA splicing**: RBM10 acts as a negative regulator of splicing by binding to specific RNA sequences and inhibiting the activity of the spliceosome. 3. **Negative regulation of transcription by RNA polymerase II**: RBM10 interacts with RNA polymerase II, regulating its activity and influencing transcriptional output. 4. **Processing of capped intron-containing pre-mRNA**: RBM10 is involved in the processing of pre-mRNAs with introns, ensuring proper splicing and translation. **Clinical Significance** Dysregulation of RBM10 has been implicated in various diseases, including: 1. **Cardiovascular disorders**: RBM10's role in regulating vascular smooth muscle cell proliferation and apoptosis makes it a potential target for cardiovascular disease therapy. 2. **Cancer**: RBM10's involvement in mRNA splicing and stabilization may contribute to cancer development and progression. 3. **Neurological disorders**: RBM10's expression in neurons and its role in regulating neural function make it a potential target for neurological disorders, such as Alzheimer's disease. In conclusion, RBM10 is a multifunctional protein that plays a crucial role in regulating various cellular processes, including RNA stability, splicing, and transcription. Its dysregulation has been implicated in several diseases, highlighting the need for further research into its potential therapeutic applications. As an expert immunologist, it's essential to recognize the significance of RBM10 in maintaining proper immune function and its potential role in autoimmune diseases.

Genular Protein ID: 1189257335

Symbol: RBM10_HUMAN

Name: G patch domain-containing protein 9

UniProtKB Accession Codes:

P98175 A0A0A0MR66 C4AM81 Q14136 Q5JRR2 Q9BTE4 Q9BTX0 Q9NTB1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 3 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 MoonDB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 2 RefSeq 5 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8590280

Title: Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 8590280

DOI: 10.1093/dnares/2.4.167

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8808293

Title: A novel gene, DXS8237E, lies within 20 kb upstream of UBE1 in Xp11.23 and has a different X inactivation status.

PubMed ID: 8808293

DOI: 10.1006/geno.1996.0022

PubMed ID: 12176931

Title: Large-scale proteomic analysis of the human spliceosome.

PubMed ID: 12176931

DOI: 10.1101/gr.473902

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20451169

Title: Massively parallel sequencing of exons on the X chromosome identifies RBM10 as the gene that causes a syndromic form of cleft palate.

PubMed ID: 20451169

DOI: 10.1016/j.ajhg.2010.04.007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 17707232

Title: A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation.

PubMed ID: 17707232

DOI: 10.1016/j.molcel.2007.07.024

PubMed ID: 18315527

Title: S1-1 nuclear domains: characterization and dynamics as a function of transcriptional activity.

PubMed ID: 18315527

DOI: 10.1042/bc20070142

PubMed ID: 28431233

Title: A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.

PubMed ID: 28431233

DOI: 10.1016/j.molcel.2017.03.014

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 930
  • Mass: 103533
  • Checksum: 472E68F085CA5744
  • Sequence:
    • MEYERRGGRG DRTGRYGATD RSQDDGGENR SRDHDYRDMD YRSYPREYGS QEGKHDYDDS 
SEEQSAEDSY EASPGSETQR RRRRRHRHSP TGPPGFPRDG DYRDQDYRTE QGEEEEEEED 
EEEEEKASNI VMLRMLPQAA TEDDIRGQLQ SHGVQAREVR LMRNKSSGQS RGFAFVEFSH 
LQDATRWMEA NQHSLNILGQ KVSMHYSDPK PKINEDWLCN KCGVQNFKRR EKCFKCGVPK 
SEAEQKLPLG TRLDQQTLPL GGRELSQGLL PLPQPYQAQG VLASQALSQG SEPSSENAND 
TIILRNLNPH STMDSILGAL APYAVLSSSN VRVIKDKQTQ LNRGFAFIQL STIVEAAQLL 
QILQALHPPL TIDGKTINVE FAKGSKRDMA SNEGSRISAA SVASTAIAAA QWAISQASQG 
GEGTWATSEE PPVDYSYYQQ DEGYGNSQGT ESSLYAHGYL KGTKGPGITG TKGDPTGAGP 
EASLEPGADS VSMQAFSRAQ PGAAPGIYQQ SAEASSSQGT AANSQSYTIM SPAVLKSELQ 
SPTHPSSALP PATSPTAQES YSQYPVPDVS TYQYDETSGY YYDPQTGLYY DPNSQYYYNA 
QSQQYLYWDG ERRTYVPALE QSADGHKETG APSKEGKEKK EKHKTKTAQQ IAKDMERWAR 
SLNKQKENFK NSFQPISSLR DDERRESATA DAGYAILEKK GALAERQHTS MDLPKLASDD 
RPSPPRGLVA AYSGESDSEE EQERGGPERE EKLTDWQKLA CLLCRRQFPS KEALIRHQQL 
SGLHKQNLEI HRRAHLSENE LEALEKNDME QMKYRDRAAE RREKYGIPEP PEPKRRKYGG 
ISTASVDFEQ PTRDGLGSDN IGSRMLQAMG WKEGSGLGRK KQGIVTPIEA QTRVRGSGLG 
ARGSSYGVTS TESYKETLHK TMVTRFNEAQ

Genular Protein ID: 3809775224

Symbol: A0A0S2Z4X1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0S2Z4X1

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 ExpressionAtlas 1 GO 3 Gene3D 2 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PROSITE-ProRule 2 Pfam 4 RefSeq 1 SAM 1 SMART 3 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 852
  • Mass: 94370
  • Checksum: BB39E0CAC9B4A8A3
  • Sequence:
    • MEYERRGGRG DRTGRYGATD RSQDDGGENR SRDHDYRDMD YRSYPREYGS QEGKHDYDDS 
SEEQSAEIRG QLQSHGVQAR EVRLMRNKSS GQSRGFAFVE FSHLQDATRW MEANQHSLNI 
LGQKVSMHYS DPKPKINEDW LCNKCGVQNF KRREKCFKCG VPKSEAEQKL PLGTRLDQQT 
LPLGGRELSQ GLLPLPQPYQ AQGVLASQAL SQGSEPSSEN ANDTIILRNL NPHSTMDSIL 
GALAPYAVLS SSNVRVIKDK QTQLNRGFAF IQLSTIEAAQ LLQILQALHP PLTIDGKTIN 
VEFAKGSKRD MASNEGSRIS AASVASTAIA AAQWAISQAS QGGEGTWATS EEPPVDYSYY 
QQDEGYGNSQ GTESSLYAHG YLKGTKGPGI TGTKGDPTGA GPEASLEPGA DSVSMQAFSR 
AQPGAAPGIY QQSAEASSSQ GTAANSQSYT IMSPAVLKSE LQSPTHPSSA LPPATSPTAQ 
ESYSQYPVPD VSTYQYDETS GYYYDPQTGL YYDPNSQYYY NAQSQQYLYW DGERRTYVPA 
LEQSADGHKE TGAPSKEGKE KKEKHKTKTA QQIAKDMERW ARSLNKQKEN FKNSFQPISS 
LRDDERRESA TADAGYAILE KKGALAERQH TSMDLPKLAS DDRPSPPRGL VAAYSGESDS 
EEEQERGGPE REEKLTDWQK LACLLCRRQF PSKEALIRHQ QLSGLHKQNL EIHRRAHLSE 
NELEALEKND MEQMKYRDRA AERREKYGIP EPPEPKRRKY GGISTASVDF EQPTRDGLGS 
DNIGSRMLQA MGWKEGSGLG RKKQGIVTPI EAQTRVRGSG LGARGSSYGV TSTESYKETL 
HKTMVTRFNE AQ

Genular Protein ID: 3214957645

Symbol: Q7Z3D7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7Z3D7

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 2 IntAct 1 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 4 RefSeq 2 SAM 1 SMART 3 SUPFAM 2

Sequence Information:

  • Length: 995
  • Mass: 110338
  • Checksum: B4046F3A44E8AF97
  • Sequence:
    • MSGSPSLTAR AEKVSVDAGR GGGESLQEAS PRLADHGSSS GGGWEVKRSQ RLRRGPSSPR 
RPYQDMEYER RGGRGDRTGR YGATDRSQDD GGENRSRDHD YRDMDYRSYP REYGSQEGKH 
DYDDSSEEQS AEDSYEASPG SETQRRRRRR HRHSPTGPPG FPRDGDYRDQ DYRTEQGEEE 
EEEEDEEEEE KASNIVMLRM LPQAATEDDI RGQLQSHGVQ AREVRLMRNK SSGQSRGFAF 
VEFSHLQDAT RWMEANQHSL NILGQKVSMH YSDPKPKINE DWLCNKCGVQ NFKRREKCFK 
CGVPKSEAEQ KLPLGTRLDQ QTLPLGGREL SQGLLPLPQP YQAQGVLASQ ALSQGSEPSS 
ENANDTIILR NLNPHSTMDS ILGALAPYAV LSSSNVRVIK DKQTQLNRGF AFIQLSTIVE 
AAQLLQILQA LHPPLTIDGK TINVEFAKGS KRDMASNEGS RISAASVAST AIAAAQWAIS 
QASQGGEGTW ATSEEPPVDY SYYQQDEGYG NSQGTESSLY AHGYLKGTKG PGITGTKGDP 
TGAGPEASLE PGADSVSMQA FSRAQPGAAP GIYQQSAEAS SSQGTAANSQ SYTIMSPAVL 
KSELQSPTHP SSALPPATSP TAQESYSQYP VPDVSTYQYD ETSGYYYDPQ TGLYYDPNSQ 
YYYNAQSQQY LYWDGERRTY VPALEQSADG HKETGAPSKE GKEKKEKHKT KTAQQIAKDM 
ERWARSLNKQ KENFKNSFQP ISSLRDDERR ESATADAGYA ILEKKGALAE RQHTSMDLPK 
LASDDRPSPP RGLVAAYSGE SDSEEEQERG GPEQEEKLTD WQKLACLLCR RQFPSKEALI 
RHQQLSGLHK QNLEIHRRAH LSENELEALE KNDMEQMKYR DRAAERREKY GIPEPPEPKR 
RKYGGISTAS VDFEQPTRDG LGSDNIGSRM LQAMGWKEGS GLGRKKQGIV TPIEAQTRVR 
GSGLGARGSS YGVTSTESYK ETLHKTMVTR FNEAQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.