Details for: KCNAB2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 115.1434
Cell Significance Index: -17.9100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 48.8853
Cell Significance Index: -19.8600 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 42.5751
Cell Significance Index: -21.9000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 40.8447
Cell Significance Index: -10.3600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 21.0894
Cell Significance Index: -20.1400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 14.6721
Cell Significance Index: -18.0900 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 7.5990
Cell Significance Index: -23.3400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 6.2415
Cell Significance Index: -16.7200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.7262
Cell Significance Index: -18.6500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 4.1259
Cell Significance Index: -9.0300 - Cell Name: early promyelocyte (CL0002154)
Fold Change: 3.3601
Cell Significance Index: 21.4500 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 2.8474
Cell Significance Index: 18.8900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 2.1278
Cell Significance Index: 62.4900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 2.0864
Cell Significance Index: 55.8100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.9999
Cell Significance Index: 401.1700 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.8741
Cell Significance Index: 23.2500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 1.8092
Cell Significance Index: 51.6300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.6822
Cell Significance Index: 113.1100 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 1.3688
Cell Significance Index: 18.2600 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.3288
Cell Significance Index: 24.5600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.2994
Cell Significance Index: 49.2100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.2857
Cell Significance Index: 56.8700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.0650
Cell Significance Index: 48.2800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.9199
Cell Significance Index: 175.0600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.7458
Cell Significance Index: 267.5100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.7432
Cell Significance Index: 47.9500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5651
Cell Significance Index: 55.9000 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.5506
Cell Significance Index: 4.4900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.4797
Cell Significance Index: 36.8100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4631
Cell Significance Index: 418.1500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.4603
Cell Significance Index: 10.0800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.4431
Cell Significance Index: 306.4500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.4041
Cell Significance Index: 47.6500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.3505
Cell Significance Index: 18.4000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2980
Cell Significance Index: 48.4600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2469
Cell Significance Index: 26.8600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.1782
Cell Significance Index: 3.8000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.1438
Cell Significance Index: 28.5400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.1223
Cell Significance Index: 7.3400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0664
Cell Significance Index: 4.6000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0652
Cell Significance Index: 122.6900 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: 0.0625
Cell Significance Index: 0.6900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0416
Cell Significance Index: 2.5600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0188
Cell Significance Index: 0.4700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0048
Cell Significance Index: 8.7700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0021
Cell Significance Index: 3.2100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0047
Cell Significance Index: -0.0800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0064
Cell Significance Index: -8.6600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0077
Cell Significance Index: -0.2700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0079
Cell Significance Index: -4.9200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0101
Cell Significance Index: -7.5100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0108
Cell Significance Index: -0.3100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0121
Cell Significance Index: -1.7600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0126
Cell Significance Index: -7.1100 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0157
Cell Significance Index: -8.5800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0256
Cell Significance Index: -16.2400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0256
Cell Significance Index: -19.3800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0257
Cell Significance Index: -11.3500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0265
Cell Significance Index: -12.0300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0287
Cell Significance Index: -21.0100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0382
Cell Significance Index: -8.0500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0406
Cell Significance Index: -0.8800 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0440
Cell Significance Index: -0.6300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0549
Cell Significance Index: -15.8100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0550
Cell Significance Index: -9.4000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0580
Cell Significance Index: -10.4600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0580
Cell Significance Index: -7.9700 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0632
Cell Significance Index: -1.3100 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.0673
Cell Significance Index: -0.6400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0782
Cell Significance Index: -1.6600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0827
Cell Significance Index: -4.6400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0846
Cell Significance Index: -2.0300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0871
Cell Significance Index: -8.9000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0918
Cell Significance Index: -5.6300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1182
Cell Significance Index: -13.7700 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.1195
Cell Significance Index: -1.4900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1213
Cell Significance Index: -14.9200 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: -0.1381
Cell Significance Index: -0.3700 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1417
Cell Significance Index: -3.6200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1446
Cell Significance Index: -18.6800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1483
Cell Significance Index: -4.7500 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.1492
Cell Significance Index: -2.9500 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1552
Cell Significance Index: -3.1200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1553
Cell Significance Index: -4.3400 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1575
Cell Significance Index: -20.1900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1590
Cell Significance Index: -18.1500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1598
Cell Significance Index: -16.6400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1623
Cell Significance Index: -10.2300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1792
Cell Significance Index: -20.5400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1831
Cell Significance Index: -5.8300 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -0.1890
Cell Significance Index: -1.5600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1924
Cell Significance Index: -6.3000 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.2028
Cell Significance Index: -2.5600 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.2370
Cell Significance Index: -5.1200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2519
Cell Significance Index: -11.8400 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.2578
Cell Significance Index: -11.2100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2644
Cell Significance Index: -20.9400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2659
Cell Significance Index: -19.8200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2697
Cell Significance Index: -14.0100 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.2763
Cell Significance Index: -3.0100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2655013555
Symbol: KCAB2_HUMAN
Name: Voltage-gated potassium channel subunit beta-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7649300
Title: Alternative splicing of the human Shaker K+ channel beta 1 gene and functional expression of the beta 2 gene product.
PubMed ID: 7649300
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11086297
Title: Subunit composition and novel localization of K+ channels in spinal cord.
PubMed ID: 11086297
DOI: 10.1002/1096-9861(20000101)429:1<166::aid-cne13>3.0.co;2-y
PubMed ID: 11825900
Title: Genetic analysis of the mammalian K+ channel beta subunit Kvbeta 2 (Kcnab2).
PubMed ID: 11825900
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21357749
Title: Cdk-mediated phosphorylation of the Kvbeta2 auxiliary subunit regulates Kv1 channel axonal targeting.
PubMed ID: 21357749
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 367
- Mass: 41000
- Checksum: 91A673F8992140DA
- Sequence:
MYPESTTGSP ARLSLRQTGS PGMIYSTRYG SPKRQLQFYR NLGKSGLRVS CLGLGTWVTF GGQITDEMAE QLMTLAYDNG INLFDTAEVY AAGKAEVVLG NIIKKKGWRR SSLVITTKIF WGGKAETERG LSRKHIIEGL KASLERLQLE YVDVVFANRP DPNTPMEETV RAMTHVINQG MAMYWGTSRW SSMEIMEAYS VARQFNLTPP ICEQAEYHMF QREKVEVQLP ELFHKIGVGA MTWSPLACGI VSGKYDSGIP PYSRASLKGY QWLKDKILSE EGRRQQAKLK ELQAIAERLG CTLPQLAIAW CLRNEGVSSV LLGASNADQL MENIGAIQVL PKLSSSIIHE IDSILGNKPY SKKDYRS
Genular Protein ID: 3137677724
Symbol: B2R776_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 353
- Mass: 39288
- Checksum: A63FEE6258C7E867
- Sequence:
MYPESTTGSP ARLSLRQTGS PGMIYRNLGK SGLRVSCLGL GTWVTFGGQI TDEMAEQLMT LAYDNGIDLF DTAEVYAAGK AEVVLGNIIK KKGWRRSSLV ITTKIFWGGK AETERGLSRK HIIEGLKASL ERLQLEYVDV VFANRPDPNT PMEETVRAMT HVINQGMAMY WGTSRWSSME IMEAYSVARQ FNLTPPICEQ AEYHMFQREK VEVQLPELFH KIGVGAMTWS PLACGIVSGK YDSGIPPYSR ASLKGYQWLK DKILSEEGRR QQAKLKELQA IAERLGCTLP QLAIAWCLRN EGVSSVLLGA SNADQLMENI GAIQVLPKLS SSIIHEIDSI LGNKPYSKKD YRS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.