Details for: AGPS
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 223.7291
Cell Significance Index: -34.8000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 136.8063
Cell Significance Index: -34.7000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 82.6480
Cell Significance Index: -39.0200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 81.1555
Cell Significance Index: -32.9700 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 71.8722
Cell Significance Index: -36.9700 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 58.1799
Cell Significance Index: -39.0400 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 34.8052
Cell Significance Index: -33.2300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 30.4147
Cell Significance Index: -37.5000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 13.6887
Cell Significance Index: -36.6700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 10.9101
Cell Significance Index: -33.5100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.6045
Cell Significance Index: -37.9000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.2531
Cell Significance Index: 447.1300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.6227
Cell Significance Index: 325.5200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.3863
Cell Significance Index: 150.7900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.3039
Cell Significance Index: 212.0700 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.1997
Cell Significance Index: 23.4200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.1906
Cell Significance Index: 71.4800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.1742
Cell Significance Index: 65.8900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.9960
Cell Significance Index: 357.2300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.8565
Cell Significance Index: 65.7300 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.7913
Cell Significance Index: 19.7800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.6880
Cell Significance Index: 42.2900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.6736
Cell Significance Index: 46.5900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.6724
Cell Significance Index: 465.0600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.5408
Cell Significance Index: 20.4800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.4996
Cell Significance Index: 22.1000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4796
Cell Significance Index: 10.3900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.4681
Cell Significance Index: 10.2500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4253
Cell Significance Index: 383.9800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.4212
Cell Significance Index: 28.3300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3646
Cell Significance Index: 199.0900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.3351
Cell Significance Index: 15.1900 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.3334
Cell Significance Index: 8.0000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2995
Cell Significance Index: 53.9900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2763
Cell Significance Index: 7.9600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.2487
Cell Significance Index: 30.5900 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.2416
Cell Significance Index: 5.1700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.2120
Cell Significance Index: 9.9700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1617
Cell Significance Index: 16.0000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1449
Cell Significance Index: 4.0500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1418
Cell Significance Index: 9.1500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1349
Cell Significance Index: 6.2900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1049
Cell Significance Index: 5.4500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0920
Cell Significance Index: 125.1100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0761
Cell Significance Index: 10.4500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0735
Cell Significance Index: 1.2600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0714
Cell Significance Index: 109.9300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.0599
Cell Significance Index: 1.5400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0527
Cell Significance Index: 10.0200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0376
Cell Significance Index: 69.3600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0362
Cell Significance Index: 68.2000 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0249
Cell Significance Index: 0.5300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0240
Cell Significance Index: 10.6100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0194
Cell Significance Index: 12.3300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0189
Cell Significance Index: 3.2200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0033
Cell Significance Index: 1.4900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0063
Cell Significance Index: -0.2200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0118
Cell Significance Index: -0.3200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0183
Cell Significance Index: -0.4900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0344
Cell Significance Index: -25.2500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0355
Cell Significance Index: -26.3200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0421
Cell Significance Index: -4.9600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0422
Cell Significance Index: -31.9100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0493
Cell Significance Index: -7.1600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0634
Cell Significance Index: -35.7500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0683
Cell Significance Index: -42.6600 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.0718
Cell Significance Index: -0.8900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0910
Cell Significance Index: -9.3000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1132
Cell Significance Index: -32.5700 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.1258
Cell Significance Index: -0.7600 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1278
Cell Significance Index: -16.3800 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.1400
Cell Significance Index: -2.0100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1715
Cell Significance Index: -22.1600 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.1716
Cell Significance Index: -2.8900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1891
Cell Significance Index: -22.0400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1957
Cell Significance Index: -41.2300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2478
Cell Significance Index: -28.3900 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.2607
Cell Significance Index: -3.7500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2670
Cell Significance Index: -18.8800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2901
Cell Significance Index: -15.1100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3045
Cell Significance Index: -19.1900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3181
Cell Significance Index: -33.1200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.3455
Cell Significance Index: -9.8600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3903
Cell Significance Index: -12.5000 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4049
Cell Significance Index: -32.0700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.4178
Cell Significance Index: -31.1400 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.4403
Cell Significance Index: -6.5000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.4497
Cell Significance Index: -12.0300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.4852
Cell Significance Index: -8.1200 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.5083
Cell Significance Index: -26.6900 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.5319
Cell Significance Index: -11.2900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.5334
Cell Significance Index: -32.7000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.5360
Cell Significance Index: -17.0700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.5516
Cell Significance Index: -18.0600 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.5758
Cell Significance Index: -11.5600 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.5826
Cell Significance Index: -11.5200 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.5845
Cell Significance Index: -15.3700 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.6239
Cell Significance Index: -7.7800 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.6663
Cell Significance Index: -9.8400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.6842
Cell Significance Index: -34.5800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3764609298
Symbol: ADAS_HUMAN
Name: Alkyldihydroxyacetonephosphate synthase, peroxisomal
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9187299
Title: Nucleotide sequence of human alkyl-dihydroxyacetonephosphate synthase cDNA reveals the presence of a peroxisomal targeting signal 2.
PubMed ID: 9187299
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8399344
Title: Ether lipid synthesis: purification and identification of alkyl dihydroxyacetone phosphate synthase from guinea-pig liver.
PubMed ID: 8399344
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 9553082
Title: Alkyl-dihydroxyacetonephosphate synthase. Fate in peroxisome biogenesis disorders and identification of the point mutation underlying a single enzyme deficiency.
PubMed ID: 9553082
PubMed ID: 11152660
Title: Impaired membrane traffic in defective ether lipid biosynthesis.
PubMed ID: 11152660
DOI: 10.1093/hmg/10.2.127
PubMed ID: 21990100
Title: Functional characterization of novel mutations in GNPAT and AGPS, causing rhizomelic chondrodysplasia punctata (RCDP) types 2 and 3.
PubMed ID: 21990100
DOI: 10.1002/humu.21623
Sequence Information:
- Length: 658
- Mass: 72912
- Checksum: 0E97AE86B513DF32
- Sequence:
MAEAAAAAGG TGLGAGASYG SAADRDRDPD PDRAGRRLRV LSGHLLGRPR EALSTNECKA RRAASAATAA PTATPAAQES GTIPKKRQEV MKWNGWGYND SKFIFNKKGQ IELTGKRYPL SGMGLPTFKE WIQNTLGVNV EHKTTSKASL NPSDTPPSVV NEDFLHDLKE TNISYSQEAD DRVFRAHGHC LHEIFLLREG MFERIPDIVL WPTCHDDVVK IVNLACKYNL CIIPIGGGTS VSYGLMCPAD ETRTIISLDT SQMNRILWVD ENNLTAHVEA GITGQELERQ LKESGYCTGH EPDSLEFSTV GGWVSTRASG MKKNIYGNIE DLVVHIKMVT PRGIIEKSCQ GPRMSTGPDI HHFIMGSEGT LGVITEATIK IRPVPEYQKY GSVAFPNFEQ GVACLREIAK QRCAPASIRL MDNKQFQFGH ALKPQVSSIF TSFLDGLKKF YITKFKGFDP NQLSVATLLF EGDREKVLQH EKQVYDIAAK FGGLAAGEDN GQRGYLLTYV IAYIRDLALE YYVLGESFET SAPWDRVVDL CRNVKERITR ECKEKGVQFA PFSTCRVTQT YDAGACIYFY FAFNYRGISD PLTVFEQTEA AAREEILANG GSLSHHHGVG KLRKQWLKES ISDVGFGMLK SVKEYVDPNN IFGNRNLL
Genular Protein ID: 358844736
Symbol: B7Z3Q4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 568
- Mass: 63847
- Checksum: F0C426A5CAF6E859
- Sequence:
MKWNGWGYND SKFIFNKKGQ IELTGKRYPL SGMGLPTFKE WIQNTLGVNV EHKTTSKASL NPSDTPPSVV NEDFLHDLKE TNISYSQEAD DRVFRAHGHC LHEIFLLREG MFERIPDIVL WPTCHDDVVK IVNLACKYNL CIIPIGGGTS VSYGLMCPAD ETRTIISLDT SQMNRILWVD ENNLTAHVEA GITGQELERQ LKESGYCTGH EPDSLEFSTV GGWVSTRASG MKKNIYGNIE DLVVHIKMVT PRGIIEKSCQ GPRMSTGPDI HHFIMGSEGT LGVITEATIK IRPVPEYQKY GSVAFPNFEQ GVACLREIAK QRCAPASIRL MDNKQFQFGH ALKPQVSSIF TSFLDGLKKF YITKFKGFDP NQLSVATLLF EGDREKVLQH EKQVYDIAAK FGGLAAGEDN GQRGYLLTYV IAYIRDLALE YYVLGESFET SAPWDRVVDL CRNVKERITR ECKEKGVQFA PFSTCRVTQT YDAGACIYFY FAFNYRGISD PLTVFEQTEA AAREEILANG GSLSHHHGVG KLRKQWLKES ISDVGFGMLK SVKEYVDPNN IFGNRNLL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.