Details for: CADPS

Gene ID: 8618

Symbol: CADPS

Ensembl ID: ENSG00000163618

Description: calcium dependent secretion activator

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 27.9078
    Cell Significance Index: 8029.9000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 16.1428
    Cell Significance Index: -35.3300
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 14.0622
    Cell Significance Index: 108.3900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 7.0109
    Cell Significance Index: 200.0700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 6.2871
    Cell Significance Index: 422.7500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 5.9401
    Cell Significance Index: 142.4600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 5.2788
    Cell Significance Index: 1893.4100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 4.2490
    Cell Significance Index: 261.1700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.5577
    Cell Significance Index: 134.7200
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 3.5532
    Cell Significance Index: 46.0800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.4413
    Cell Significance Index: 690.3200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.3376
    Cell Significance Index: 147.6300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 2.5619
    Cell Significance Index: 82.0600
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 2.3794
    Cell Significance Index: 20.9600
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 2.3097
    Cell Significance Index: 24.0600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 2.2459
    Cell Significance Index: 172.3500
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 2.1477
    Cell Significance Index: 30.1700
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 1.6120
    Cell Significance Index: 19.5400
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 1.5900
    Cell Significance Index: 21.2100
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 1.3711
    Cell Significance Index: 15.4900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.3597
    Cell Significance Index: 71.3900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.3501
    Cell Significance Index: 75.7600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.1614
    Cell Significance Index: 25.4300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 1.1428
    Cell Significance Index: 19.5900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8935
    Cell Significance Index: 806.7900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.7204
    Cell Significance Index: 104.7200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6264
    Cell Significance Index: 61.9600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.4093
    Cell Significance Index: 630.1100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3778
    Cell Significance Index: 23.8100
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.3479
    Cell Significance Index: 3.7900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3155
    Cell Significance Index: 51.3200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3033
    Cell Significance Index: 8.7400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.2909
    Cell Significance Index: 536.5200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2331
    Cell Significance Index: 438.9100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2009
    Cell Significance Index: 38.2300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1634
    Cell Significance Index: 5.7400
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.1556
    Cell Significance Index: 1.4800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.1188
    Cell Significance Index: 2.3500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1054
    Cell Significance Index: 11.4600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0674
    Cell Significance Index: 91.6000
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.0378
    Cell Significance Index: 0.2900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0026
    Cell Significance Index: -0.5100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0290
    Cell Significance Index: -1.2600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0331
    Cell Significance Index: -24.5500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0813
    Cell Significance Index: -51.6600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0897
    Cell Significance Index: -10.4500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0935
    Cell Significance Index: -1.3800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0961
    Cell Significance Index: -54.2200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0991
    Cell Significance Index: -72.6500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1073
    Cell Significance Index: -81.1800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1145
    Cell Significance Index: -71.5000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.1305
    Cell Significance Index: -57.7100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1309
    Cell Significance Index: -59.4300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1353
    Cell Significance Index: -4.4300
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1492
    Cell Significance Index: -1.8600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.1568
    Cell Significance Index: -85.6100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1692
    Cell Significance Index: -2.5500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1992
    Cell Significance Index: -9.0300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2492
    Cell Significance Index: -5.2900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2625
    Cell Significance Index: -44.8300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2719
    Cell Significance Index: -5.8900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2783
    Cell Significance Index: -58.6100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2970
    Cell Significance Index: -9.4600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3125
    Cell Significance Index: -4.4700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.3333
    Cell Significance Index: -60.0800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.3365
    Cell Significance Index: -23.2700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3642
    Cell Significance Index: -41.7200
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.3805
    Cell Significance Index: -4.7200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.4085
    Cell Significance Index: -6.3200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.4236
    Cell Significance Index: -25.4300
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.4315
    Cell Significance Index: -5.1600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.4960
    Cell Significance Index: -68.1200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.5076
    Cell Significance Index: -62.4200
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.5159
    Cell Significance Index: -4.8900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5396
    Cell Significance Index: -63.6300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.5504
    Cell Significance Index: -71.1100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.5579
    Cell Significance Index: -11.2000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.5724
    Cell Significance Index: -73.3800
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.6394
    Cell Significance Index: -7.4600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.6941
    Cell Significance Index: -70.9000
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -0.7009
    Cell Significance Index: -8.0400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.7514
    Cell Significance Index: -78.2400
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.7716
    Cell Significance Index: -5.0200
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.7738
    Cell Significance Index: -10.8200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8022
    Cell Significance Index: -49.1900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.8030
    Cell Significance Index: -56.7900
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.8145
    Cell Significance Index: -10.2800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.8297
    Cell Significance Index: -10.4700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.9581
    Cell Significance Index: -71.4100
  • Cell Name: flat midget bipolar cell (CL4033033)
    Fold Change: -1.0290
    Cell Significance Index: -12.7900
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -1.0379
    Cell Significance Index: -25.8900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -1.0502
    Cell Significance Index: -22.6900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.1492
    Cell Significance Index: -40.2600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -1.1559
    Cell Significance Index: -24.1300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -1.2519
    Cell Significance Index: -25.9700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -1.2609
    Cell Significance Index: -81.3500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.3315
    Cell Significance Index: -62.0800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -1.3963
    Cell Significance Index: -16.6500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.4326
    Cell Significance Index: -74.4200
  • Cell Name: invaginating midget bipolar cell (CL4033034)
    Fold Change: -1.4369
    Cell Significance Index: -17.7400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Calcium-dependent secretion activator**: CADPS is a calcium-dependent protein that regulates exocytosis by modulating the activity of calcium channels and pumps. 2. **Specific expression in photoreceptor cells, endocrine cells, and neurons**: CADPS is predominantly expressed in photoreceptor cells, endocrine cells, and neurons, indicating its involvement in sensory and motor functions. 3. **Involvement in glutamatergic synapse and synaptic vesicle exocytosis**: CADPS is implicated in the regulation of glutamatergic synapses and synaptic vesicle exocytosis, highlighting its role in neurotransmission and synaptic plasticity. 4. **Positive regulation of exocytosis**: CADPS acts as a positive regulator of exocytosis, suggesting its involvement in enhancing the release of cellular contents. **Pathways and Functions:** 1. **Dense core granule exocytosis**: CADPS regulates the exocytosis of dense core granules, which are involved in the release of hormones and neurotransmitters. 2. **Exocytosis**: CADPS modulates the activity of calcium channels and pumps, leading to the regulation of exocytosis in various cell types. 3. **Glutamatergic synapse**: CADPS is involved in the regulation of glutamatergic synapses, which are essential for synaptic plasticity and learning. 4. **Lipid binding and metal ion binding**: CADPS exhibits lipid-binding and metal ion-binding properties, suggesting its involvement in cellular membrane dynamics and protein-protein interactions. **Clinical Significance:** 1. **Neurological disorders**: CADPS dysregulation has been implicated in various neurological disorders, including epilepsy, Parkinson's disease, and Alzheimer's disease. 2. **Immune system disorders**: CADPS is also involved in immune system regulation, and its dysregulation may contribute to autoimmune diseases and immunodeficiency disorders. 3. **Endocrine disorders**: CADPS plays a role in endocrine function, and its dysregulation may contribute to endocrine disorders, such as diabetes and thyroid disease. 4. **Cancer**: CADPS has been implicated in cancer progression and metastasis, highlighting its potential as a therapeutic target. In conclusion, CADPS is a critical regulator of exocytosis and cellular signaling, with significant implications for our understanding of neurological, immunological, and endocrine disorders. Further research is necessary to elucidate the mechanisms underlying CADPS dysregulation and to explore its potential as a therapeutic target.

Genular Protein ID: 1645032962

Symbol: CAPS1_HUMAN

Name: Calcium-dependent secretion activator 1

UniProtKB Accession Codes:

Q9ULU8 A6NF60 Q13339 Q6GQQ6 Q8N2Z5 Q8N3M7 Q8NFR0 Q96BC2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 EMBL 8 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 RefSeq 3 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12659812

Title: Cloning and characterization of human CADPS and CADPS2, new members of the Ca2+-dependent activator for secretion protein family.

PubMed ID: 12659812

DOI: 10.1016/s0888-7543(02)00040-x

PubMed ID: 10574461

Title: Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.

PubMed ID: 10574461

DOI: 10.1093/dnares/6.5.329

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 9289490

Title: Novel Ca2+-binding protein (CAPS) related to UNC-31 required for Ca2+-activated exocytosis.

PubMed ID: 9289490

DOI: 10.1074/jbc.272.32.19637

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15857609

Title: Regulation of dense core vesicle release from PC12 cells by interaction between the D2 dopamine receptor and calcium-dependent activator protein for secretion (CAPS).

PubMed ID: 15857609

DOI: 10.1016/j.bcp.2005.02.015

Sequence Information:

  • Length: 1353
  • Mass: 152786
  • Checksum: 9911C50B3A507112
  • Sequence:
    • MLDPSSSEEE SDEIVEEESG KEVLGSAPSG ARLSPSRTSE GSAGSAGLGG GGAGAGAGVG 
AGGGGGSGAS SGGGAGGLQP SSRAGGGRPS SPSPSVVSEK EKEELERLQK EEEERKKRLQ 
LYVFVMRCIA YPFNAKQPTD MARRQQKISK QQLQTVKDRF QAFLNGETQI MADEAFMNAV 
QSYYEVFLKS DRVARMVQSG GCSANDSREV FKKHIEKRVR SLPEIDGLSK ETVLSSWMAK 
FDAIYRGEED PRKQQARMTA SAASELILSK EQLYEMFQNI LGIKKFEHQL LYNACQLDNP 
DEQAAQIRRE LDGRLQMADQ IARERKFPKF VSKEMENMYI EELKSSVNLL MANLESMPVS 
KGGEFKLQKL KRSHNASIID MGEESENQLS KSDVVLSFSL EVVIMEVQGL KSLAPNRIVY 
CTMEVEGGEK LQTDQAEASK PTWGTQGDFS TTHALPAVKV KLFTESTGVL ALEDKELGRV 
ILHPTPNSPK QSEWHKMTVS KNCPDQDLKI KLAVRMDKPQ NMKHSGYLWA IGKNVWKRWK 
KRFFVLVQVS QYTFAMCSYR EKKAEPQELL QLDGYTVDYT DPQPGLEGGR AFFNAVKEGD 
TVIFASDDEQ DRILWVQAMY RATGQSHKPV PPTQVQKLNA KGGNVPQLDA PISQFYADRA 
QKHGMDEFIS SNPCNFDHAS LFEMVQRLTL DHRLNDSYSC LGWFSPGQVF VLDEYCARNG 
VRGCHRHLCY LRDLLERAEN GAMIDPTLLH YSFAFCASHV HGNRPDGIGT VTVEEKERFE 
EIKERLRVLL ENQITHFRYC FPFGRPEGAL KATLSLLERV LMKDIVTPVP QEEVKTVIRK 
CLEQAALVNY SRLSEYAKIE ENQKDAENVG RLITPAKKLE DTIRLAELVI EVLQQNEEHH 
AEPHVDKGEA FAWWSDLMVE HAETFLSLFA VDMDAALEVQ PPDTWDSFPL FQLLNDFLRT 
DYNLCNGKFH KHLQDLFAPL VVRYVDLMES SIAQSIHRGF ERESWEPVKS LTSNLPNVNL 
PNVNLPKVPN LPVNIPLGIP QMPTFSAPSW MAAIYDADNG SGTSEDLFWK LDALQTFIRD 
LHWPEEEFGK HLEQRLKLMA SDMIESCVKR TRIAFEVKLQ KTSRSTDFRV PQSICTMFNV 
MVDAKAQSTK LCSMEMGQEH QYHSKIDELI EETVKEMITL LVAKFVTILE GVLAKLSRYD 
EGTLFSSFLS FTVKAASKYV DVPKPGMDVA DAYVTFVRHS QDVLRDKVNE EMYIERLFDQ 
WYNSSMNVIC TWLTDRMDLQ LHIYQLKTLI RMVKKTYRDF RLQGVLDSTL NSKTYETIRN 
RLTVEEATAS VSEGGGLQGI SMKDSDEEDE EDD

Genular Protein ID: 2553662250

Symbol: F1T0E5_HUMAN

Name: N/A

UniProtKB Accession Codes:

F1T0E5

Database IDs:

ARBA 3 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 2 GO 5 Gene3D 2 GeneTree 1 HGNC 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 21697133

Title: Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.

PubMed ID: 21697133

DOI: 10.1167/iovs.11-7479

Sequence Information:

  • Length: 1344
  • Mass: 152001
  • Checksum: 1E3800FA8B52B046
  • Sequence:
    • MLDPSSSEEE SDEIVEEESG KEVLGSAPSG ARLSPSRTSE GSAGSAGLGG GGAGAGAGVG 
AGGGGGSGAS SGGGAGGLQP SSRAGGGRPS SPSPSVVSEK EKEELERLQK EEEERKKRLQ 
LYVFVMRCIA YPFNAKQPTD MARRQQKISK QQLQTVKDRF QAFLNGETQI MADEAFMNAV 
QSYYEVFLKS DRVARMVQSG GCSANDSREV FKKHIEKRVR SLPEIDGLSK ETVLSSWMAK 
FDAIYRGEED PRKQQARMTA SAASELILSK EQLYEMFQNI LGIKKFEHQL LYNACQLDNP 
DEQAAQIRRE LDGRLQMADQ IARERKFPKF VSKEMENMYI EELKSSVNLL MANLESMPVS 
KGGEFKLQKL KRSHNASIID MGEESENQLS KSDVVLSFSL EVVIMEVQGL KSLAPNRIVY 
CTMEVEGGEK LQTDQAEASK PTWGTQGDFS TTHALPAVKV KLFTESTGVL ALEDKELGRV 
ILHPTPNSPK QSEWHKMTVS KNCPDQDLKI KLAVRMDKPQ NMKHSGYLWA IGKNVWKRWK 
KRFFVLVQVS QYTFAMCSYR EKKAEPQELL QLDGYTVDYT DPQPGLEGGR AFFNAVKEGD 
TVIFASDDEQ DRILWVQAMY RATGQSHKPV PPTQVQKLNA KGGNVPQLDA PISQFYADRA 
QKHGMDEFIS SNPCNFDHAS LFEMVQRLTL DHRLNDSYSC LGWFSPGQVF VLDEYCARNG 
VRGCHRHLCY LRDLLERAEN GAMIDPTLLH YSFAFCASHV HGNSQQMHVY LSGLPPNTDP 
EGSKTPSPPE PEAKKDTKKE SKKRKDSKTQ ANQELKRPDG IGTVTVEEKE RFEEIKERLR 
VLLENQITHF RYCFPFGRPE GALKATLSLL ERVLMKDIVT PVPQEEVKTV IRKCLEQAAL 
VNYSRLSEYA KIEENVGRLI TPAKKLEDTI RLAELVIEVL QQNEEHHAEA FAWWSDLMVE 
HAETFLSLFA VDMDAALEVQ PPDTWDSFPL FQLLNDFLRT DYNLCNGKFH KHLQDLFAPL 
VVRYVDLMES SIAQSIHRGF ERESWEPVNN GSGTSEDLFW KLDALQTFIR DLHWPEEEFG 
KHLEQRLKLM ASDMIESCVK RTRIAFEVKL QKTSRSTDFR VPQSICTMFN VMVDAKAQST 
KLCSMEMGQE HQYHSKIDEL IEETVKEMIT LLVAKFVTIL EGVLAKLSRY DEGTLFSSFL 
SFTVKAASKY VDVPKPGMDV ADAYVTFVRH SQDVLRDKVN EEMYIERLFD QWYNSSMNVI 
CTWLTDRMDL QLHIYQLKTL IRMVKKTYRD FRLQGVLDST LNSKTYETIR NRLTVEEATA 
SVSEGGGLQG ISMKDSDEED EEDD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.