Details for: ADAM19

Gene ID: 8728

Symbol: ADAM19

Ensembl ID: ENSG00000135074

Description: ADAM metallopeptidase domain 19

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 114.8219
    Cell Significance Index: -17.8600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 70.9264
    Cell Significance Index: -17.9900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 39.6793
    Cell Significance Index: -16.1200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 37.9562
    Cell Significance Index: -17.9200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 14.4774
    Cell Significance Index: -17.8500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.8414
    Cell Significance Index: -14.8700
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 2.7199
    Cell Significance Index: 16.9000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.9563
    Cell Significance Index: 23.3200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.5145
    Cell Significance Index: 116.2200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.2842
    Cell Significance Index: 257.6000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.2303
    Cell Significance Index: 36.1300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.1631
    Cell Significance Index: 221.3400
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.0374
    Cell Significance Index: 14.5700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.9899
    Cell Significance Index: 14.2200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.9686
    Cell Significance Index: 20.7100
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.9043
    Cell Significance Index: 6.9700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.7812
    Cell Significance Index: 17.1100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6994
    Cell Significance Index: 631.5300
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: 0.6921
    Cell Significance Index: 11.8900
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.6775
    Cell Significance Index: 10.8700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.6576
    Cell Significance Index: 15.7700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.6524
    Cell Significance Index: 40.1000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.5957
    Cell Significance Index: 37.5500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.5172
    Cell Significance Index: 60.9900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.4467
    Cell Significance Index: 5.5400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.4247
    Cell Significance Index: 6.2700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4003
    Cell Significance Index: 22.4600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3803
    Cell Significance Index: 61.8600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3537
    Cell Significance Index: 70.2000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2732
    Cell Significance Index: 29.7200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2315
    Cell Significance Index: 160.1100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.2278
    Cell Significance Index: 103.3900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2173
    Cell Significance Index: 21.5000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1925
    Cell Significance Index: 69.0500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.1778
    Cell Significance Index: 3.4700
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.1623
    Cell Significance Index: 2.3100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: 0.1264
    Cell Significance Index: 26.6200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1248
    Cell Significance Index: 8.6300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0793
    Cell Significance Index: 50.3600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.0625
    Cell Significance Index: 6.5100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0607
    Cell Significance Index: 1.0400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0426
    Cell Significance Index: 26.6200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0268
    Cell Significance Index: 0.6900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0077
    Cell Significance Index: 1.3900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0037
    Cell Significance Index: 0.2200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.0032
    Cell Significance Index: 0.0400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0026
    Cell Significance Index: 0.0800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0048
    Cell Significance Index: -0.1700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0052
    Cell Significance Index: -9.7400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0055
    Cell Significance Index: -7.5400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0070
    Cell Significance Index: -10.7100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0078
    Cell Significance Index: -14.4500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0083
    Cell Significance Index: -6.1600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0116
    Cell Significance Index: -6.5300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0170
    Cell Significance Index: -2.3400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0190
    Cell Significance Index: -0.3200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0238
    Cell Significance Index: -17.9800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0242
    Cell Significance Index: -17.7300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0277
    Cell Significance Index: -15.1300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0335
    Cell Significance Index: -14.8100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0406
    Cell Significance Index: -0.8800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0450
    Cell Significance Index: -2.0400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0488
    Cell Significance Index: -1.2200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0502
    Cell Significance Index: -8.5800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0508
    Cell Significance Index: -14.6300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0620
    Cell Significance Index: -0.4200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0675
    Cell Significance Index: -9.8100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0716
    Cell Significance Index: -1.5300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0941
    Cell Significance Index: -1.8900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0980
    Cell Significance Index: -12.0500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1052
    Cell Significance Index: -13.4800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1286
    Cell Significance Index: -14.9900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1377
    Cell Significance Index: -15.7200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.1409
    Cell Significance Index: -2.0800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1416
    Cell Significance Index: -16.2200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1427
    Cell Significance Index: -18.4300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1428
    Cell Significance Index: -2.0500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1480
    Cell Significance Index: -7.7700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1661
    Cell Significance Index: -16.9700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1715
    Cell Significance Index: -2.8700
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.1741
    Cell Significance Index: -2.1100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1762
    Cell Significance Index: -10.8000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1802
    Cell Significance Index: -5.9000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1819
    Cell Significance Index: -5.1900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1825
    Cell Significance Index: -12.2700
  • Cell Name: diffuse bipolar 2 cell (CL4033028)
    Fold Change: -0.1946
    Cell Significance Index: -2.3900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2041
    Cell Significance Index: -6.5000
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.2084
    Cell Significance Index: -2.6300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2186
    Cell Significance Index: -16.2900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2225
    Cell Significance Index: -4.4000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2262
    Cell Significance Index: -6.0400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2265
    Cell Significance Index: -6.3300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2331
    Cell Significance Index: -12.1400
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.2419
    Cell Significance Index: -2.5200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2475
    Cell Significance Index: -15.9700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2679
    Cell Significance Index: -8.5800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2684
    Cell Significance Index: -11.8700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2857
    Cell Significance Index: -10.8200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2887
    Cell Significance Index: -13.5700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2889
    Cell Significance Index: -15.0100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** ADAM19 shares several key characteristics with other ADAM family members, including: 1. **Metalloprotease domain**: ADAM19 contains a zinc-dependent metalloprotease domain, which is involved in the cleavage of protein substrates. 2. **Disintegrin domain**: ADAM19 also possesses a disintegrin domain, which is involved in cell-cell adhesion and cell migration. 3. **Heterodimerization**: ADAM19 can form heterodimers with other ADAM family members, which can modulate its activity and substrate specificity. **Pathways and Functions** ADAM19 is involved in several key cellular processes, including: 1. **Cell-cell adhesion**: ADAM19 regulates cell-cell adhesion by cleaving and modulating the activity of adhesion molecules, such as cadherins. 2. **Protein processing**: ADAM19 is involved in the processing and cleavage of various protein substrates, including the amyloid precursor protein (APP). 3. **Cell migration**: ADAM19 regulates cell migration by modulating the activity of proteases involved in the degradation of the extracellular matrix. 4. **Regulation of gene expression**: ADAM19 can regulate gene expression by interacting with transcription factors and modulating the activity of signaling pathways. **Clinical Significance** ADAM19 has been implicated in several disease processes, including: 1. **Amyloidosis**: ADAM19 is involved in the processing and cleavage of APP, which can lead to the formation of amyloid plaques in Alzheimer's disease. 2. **Cardiac disease**: ADAM19 is expressed in cardiac myocytes and has been implicated in the regulation of cardiac function and the development of cardiac disease. 3. **Cancer**: ADAM19 has been shown to be overexpressed in various types of cancer, including breast, lung, and colon cancer, and may play a role in tumor progression and metastasis. In summary, ADAM19 is a multifunctional protein that plays a critical role in regulating various cellular processes, including cell-cell adhesion, protein processing, and gene expression. Its dysregulation has been implicated in several disease processes, highlighting the importance of further research into the functions and mechanisms of ADAM19.

Genular Protein ID: 2876339526

Symbol: ADA19_HUMAN

Name: Disintegrin and metalloproteinase domain-containing protein 19

UniProtKB Accession Codes:

Q9H013 Q9BZL5 Q9UHP2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 5 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 7 Ensembl 2 ExpressionAtlas 1 GO 13 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 2 RefSeq 2 SABIO-RK 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10887142

Title: Molecular cloning and characterization of a human metalloprotease disintegrin a novel marker for dendritic cell differentiation.

PubMed ID: 10887142

PubMed ID: 11162584

Title: Expression and enzymatic activity of human disintegrin and metalloproteinase ADAM19/meltrin beta.

PubMed ID: 11162584

DOI: 10.1006/bbrc.2000.4200

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 12615925

Title: The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells.

PubMed ID: 12615925

DOI: 10.1074/jbc.m300267200

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 18772397

Title: Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.

PubMed ID: 18772397

DOI: 10.1126/science.1164368

Sequence Information:

  • Length: 955
  • Mass: 104997
  • Checksum: 9C9D42BED18BF7F9
  • Sequence:
    • MPGGAGAARL CLLAFALQPL RPRAAREPGW TRGSEEGSPK LQHELIIPQW KTSESPVREK 
HPLKAELRVM AEGRELILDL EKNEQLFAPS YTETHYTSSG NPQTTTRKLE DHCFYHGTVR 
ETELSSVTLS TCRGIRGLIT VSSNLSYVIE PLPDSKGQHL IYRSEHLKPP PGNCGFEHSK 
PTTRDWALQF TQQTKKRPRR MKREDLNSMK YVELYLVADY LEFQKNRRDQ DATKHKLIEI 
ANYVDKFYRS LNIRIALVGL EVWTHGNMCE VSENPYSTLW SFLSWRRKLL AQKYHDNAQL 
ITGMSFHGTT IGLAPLMAMC SVYQSGGVNM DHSENAIGVA ATMAHEMGHN FGMTHDSADC 
CSASAADGGC IMAAATGHPF PKVFNGCNRR ELDRYLQSGG GMCLSNMPDT RMLYGGRRCG 
NGYLEDGEEC DCGEEEECNN PCCNASNCTL RPGAECAHGS CCHQCKLLAP GTLCREQARQ 
CDLPEFCTGK SPHCPTNFYQ MDGTPCEGGQ AYCYNGMCLT YQEQCQQLWG PGARPAPDLC 
FEKVNVAGDT FGNCGKDMNG EHRKCNMRDA KCGKIQCQSS EARPLESNAV PIDTTIIMNG 
RQIQCRGTHV YRGPEEEGDM LDPGLVMTGT KCGYNHICFE GQCRNTSFFE TEGCGKKCNG 
HGVCNNNQNC HCLPGWAPPF CNTPGHGGSI DSGPMPPESV GPVVAGVLVA ILVLAVLMLM 
YYCCRQNNKL GQLKPSALPS KLRQQFSCPF RVSQNSGTGH ANPTFKLQTP QGKRKVINTP 
EILRKPSQPP PRPPPDYLRG GSPPAPLPAH LSRAARNSPG PGSQIERTES SRRPPPSRPI 
PPAPNCIVSQ DFSRPRPPQK ALPANPVPGR RSLPRPGGAS PLRPPGAGPQ QSRPLAALAP 
KVSPREALKV KAGTRGLQGG RCRVEKTKQF MLLVVWTELP EQKPRAKHSC FLVPA

Genular Protein ID: 111863836

Symbol: Q8TBU7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8TBU7 Q8N504

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 3 Gene3D 2 InterPro 5 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 6 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2 SMART 2 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 488
  • Mass: 52722
  • Checksum: F9D288B23529BC05
  • Sequence:
    • DCGEEEECNN PCCNASNCTL RPGAECAHGS CCHQCKLLAP GTLCREQARQ CDLPEFCTGK 
SPHCPTNFYQ MDGTPCEGGQ AYCYNGMCLT YQEQCQQLWG PGARPAPDLC FEKVNVAGDT 
FGNCGKDMNG EHRKCNMRDA KCGKIQCQSS EARPLESNAV PIDTTIIMNG RQIQCRGTHV 
YRGPEEEGDM LDPGLVMTGT KCGYNHICFE GQCRNTSFFE TEGCGKKCNG HGVCNNNQNC 
HCLPGWAPPF CNTPGHGGSI DSGPMPPESV GPVVAGVLVA ILVLAVLMLM YYCCRQNNKL 
GQLKPSALPS KLRQQFSCPF RVSQNSGTGH ANPTFKLQTP QGKRKVINTP EILRKPSQPP 
PRPPPDYLRG GSPPAPLPAH LSRAARNSPG PGSQIERTES SRRPPPSRPI PPAPNCIVSQ 
DFSRPRPPQK ALPANPVPGR RSLPRPGGAS PLRPPGAGPQ QSRPLAALAP KRVWKTCNLK 
TGDQFQSQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.