Details for: EIF2B4

Gene ID: 8890

Symbol: EIF2B4

Ensembl ID: ENSG00000115211

Description: eukaryotic translation initiation factor 2B subunit delta

Associated with

Other Information

Genular Protein ID: 1209781372

Symbol: EI2BD_HUMAN

Name: Translation initiation factor eIF2B subunit delta

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10931946

Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.

PubMed ID: 10931946

DOI: 10.1073/pnas.160270997

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28169297

Title: Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction.

PubMed ID: 28169297

DOI: 10.1038/ncomms13876

PubMed ID: 25858979

Title: Stress responses. Mutations in a translation initiation factor identify the target of a memory-enhancing compound.

PubMed ID: 25858979

DOI: 10.1126/science.aaa6986

PubMed ID: 27023709

Title: Expression, purification, and crystallization of Schizosaccharomyces pombe eIF2B.

PubMed ID: 27023709

DOI: 10.1007/s10969-016-9203-3

PubMed ID: 31048492

Title: Structural basis for eIF2B inhibition in integrated stress response.

PubMed ID: 31048492

DOI: 10.1126/science.aaw4104

PubMed ID: 11835386

Title: Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter.

PubMed ID: 11835386

DOI: 10.1002/ana.10112

PubMed ID: 12707859

Title: Ovarian failure related to eukaryotic initiation factor 2B mutations.

PubMed ID: 12707859

DOI: 10.1086/375404

PubMed ID: 15776425

Title: Identification of ten novel mutations in patients with eIF2B-related disorders.

PubMed ID: 15776425

DOI: 10.1002/humu.9325

Sequence Information:

  • Length: 523
  • Mass: 57557
  • Checksum: 5F38CF10CAD5A45E
  • Sequence:
  • MAAVAVAVRE DSGSGMKAEL PPGPGAVGRE MTKEEKLQLR KEKKQQKKKR KEEKGAEPET 
    GSAVSAAQCQ VGPTRELPES GIQLGTPREK VPAGRSKAEL RAERRAKQEA ERALKQARKG 
    EQGGPPPKAS PSTAGETPSG VKRLPEYPQV DDLLLRRLVK KPERQQVPTR KDYGSKVSLF 
    SHLPQYSRQN SLTQFMSIPS SVIHPAMVRL GLQYSQGLVS GSNARCIALL RALQQVIQDY 
    TTPPNEELSR DLVNKLKPYM SFLTQCRPLS ASMHNAIKFL NKEITSVGSS KREEEAKSEL 
    RAAIDRYVQE KIVLAAQAIS RFAYQKISNG DVILVYGCSS LVSRILQEAW TEGRRFRVVV 
    VDSRPWLEGR HTLRSLVHAG VPASYLLIPA ASYVLPEVSK VLLGAHALLA NGSVMSRVGT 
    AQLALVARAH NVPVLVCCET YKFCERVQTD AFVSNELDDP DDLQCKRGEH VALANWQNHA 
    SLRLLNLVYD VTPPELVDLV ITELGMIPCS SVPVVLRVKS SDQ

Genular Protein ID: 3282434288

Symbol: Q9HBP7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 229
  • Mass: 25208
  • Checksum: 5FF5D040883554F6
  • Sequence:
  • MKAELPPGPG AVGREMTKEE KLQLRKEKKQ QKKKRKEEKG AEPETGSAVS AAQCQVGPTR 
    ELPESGIQLG TPREKVPAGR SKAELRAERR AKQEAERALK QARKGEQGGP PPKASPSTAG 
    ETPSGVKRLP EYPQVDDLLL RRLVKKPERQ QVPTRKDYGS KVSLFSHLPQ YSRQNSLTQF 
    MSIPSSVIHP AMVRLGLQYS QGLVSGSNAR CIALLRALQQ VIQDYTTPA

Genular Protein ID: 1714936127

Symbol: Q71US4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 520
  • Mass: 57554
  • Checksum: 6CBF93DDFAD511BC
  • Sequence:
  • MAAVAVAVRE DSGSGMKADS PWAWVGREMT KEEKLQLRKE KKQQKKKRKE EKGAEPETGS 
    AVSAAQCQGP TRELPESGIQ LGTPREKVPA GRSKAELRAE RRAKQEAERA LKQARKGEQG 
    GPPPKASPST AEETPSGVKR LPEYPQVDDL LLRRLVKKPE RQQVPTRKDY GSKVSLFSHL 
    PQYSRQNSLT QFMSIPSSVI HPAMVRLGLQ YSQGLVSGSN ARCIALLRAL QQVIQDYTTP 
    PNEELSRDLV NKLKPYMSFL TQCRPLSASM HNAIKFLNKE ITSVGSSKRE EEAKSELRAA 
    IDRYVQEKIV LAAQAISRFA YQKISNGDVI LVYGCSSLVS RILQEAWTEG RRFRVVVVDS 
    RPWLEGRHTL RSLVHAGVPA SYLLIPAASY VLPEVSKVLL GAHALLANGS VMSRVGTAQL 
    ALVARAHNVP VLVCCETYKF CERVQTDAFV SNELDDPDDL QCKRGEHVAL ANWQNHASLR 
    LLNLVYDVTP PELVDLVITE LGMIPCSSVP VVLRVKSSDQ

Genular Protein ID: 4110477445

Symbol: F8W8L6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 235
  • Mass: 25389
  • Checksum: 470492A86957AC9A
  • Sequence:
  • MAAVAVAVRE DSGSGMKAEL PPGPGAVGRE MTKEEKLQLR KEKKQQKKKR KEEKGAEPET 
    GSAVSAAQCQ VGPTRELPES GIQLGTPREK VPAGRSKAEL RAERRAKQEA ERALKQARKG 
    EQGGPPPKAS PSTAGETPSG VKRLPEYPQV DDLLLRRLVK KPERQQVPTR KDYGSKVSLF 
    SHLPQYSRQN SLTQFMSHGA TRPAVLPGPG QWLQCPVYCP ASCLAAGDSG LHNTA

Genular Protein ID: 3501305960

Symbol: B4DUP5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 312
  • Mass: 34797
  • Checksum: 4FD32AF402B32CD8
  • Sequence:
  • MKAELPPGPG AVGREMTKEE KLQLRKEKKQ QKKKRKEEKG AEPETGSAVS AAQCQGPTRE 
    LPESGIQLGT PREKVPAGRS KAELRAERRA KQEAERALKQ ARKGEQGGPP PKASPSTAGE 
    TPSGVKRLPE YPQVDDLLLR RLVKKPERQQ VPTRKDYGSK VSLFSHLPQY SRQNSLTQFM 
    SIPSSVIHPA MVRLGLQYSQ GLVSGSNARC IALLRALQQV IQDYTTPPNE ELSRDLVNKL 
    KPYMSFLTQC RPLSASMHNA IKFLNKEITS VGSSKREEEV MSMRNKEGMH LWVKLRNMLK 
    TPGKANVSLF LP

Genular Protein ID: 2012007295

Symbol: E7ERK9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 544
  • Mass: 59715
  • Checksum: 80573AA59A7458CB
  • Sequence:
  • MPTQQPAAPS TRAPKPSRSL SGSLCALFSD ADSGSGMKAE LPPGPGAVGR EMTKEEKLQL 
    RKEKKQQKKK RKEEKGAEPE TGSAVSAAQC QVGPTRELPE SGIQLGTPRE KVPAGRSKAE 
    LRAERRAKQE AERALKQARK GEQGGPPPKA SPSTAGETPS GVKRLPEYPQ VDDLLLRRLV 
    KKPERQQVPT RKDYGSKVSL FSHLPQYSRQ NSLTQFMSIP SSVIHPAMVR LGLQYSQGLV 
    SGSNARCIAL LRALQQVIQD YTTPPNEELS RDLVNKLKPY MSFLTQCRPL SASMHNAIKF 
    LNKEITSVGS SKREEEAKSE LRAAIDRYVQ EKIVLAAQAI SRFAYQKISN GDVILVYGCS 
    SLVSRILQEA WTEGRRFRVV VVDSRPWLEG RHTLRSLVHA GVPASYLLIP AASYVLPEVS 
    KVLLGAHALL ANGSVMSRVG TAQLALVARA HNVPVLVCCE TYKFCERVQT DAFVSNELDD 
    PDDLQCKRGE HVALANWQNH ASLRLLNLVY DVTPPELVDL VITELGMIPC SSVPVVLRVK 
    SSDQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.