Details for: MAP3K14
Associated with
Other Information
Genular Protein ID: 2905303571
Symbol: M3K14_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9020361
Title: MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1.
PubMed ID: 9020361
DOI: 10.1038/385540a0
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12874243
Title: Pellino3, a novel member of the Pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein.
PubMed ID: 12874243
PubMed ID: 12853971
Title: NIK is a component of the EGF/heregulin receptor signaling complexes.
PubMed ID: 12853971
PubMed ID: 15084608
Title: Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation.
PubMed ID: 15084608
PubMed ID: 15173580
Title: beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha.
PubMed ID: 15173580
PubMed ID: 15951441
Title: NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation.
PubMed ID: 15951441
PubMed ID: 17237370
Title: Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes.
PubMed ID: 17237370
PubMed ID: 20501937
Title: Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation.
PubMed ID: 20501937
PubMed ID: 30341167
Title: DDX3 directly facilitates IKKalpha activation and regulates downstream signalling pathways.
PubMed ID: 30341167
DOI: 10.1042/bcj20180163
PubMed ID: 22718757
Title: Structure of the nuclear factor kappaB-inducing kinase (NIK) kinase domain reveals a constitutively active conformation.
PubMed ID: 22718757
PubMed ID: 22921830
Title: The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site.
PubMed ID: 22921830
PubMed ID: 17344846
Title: Patterns of somatic mutation in human cancer genomes.
PubMed ID: 17344846
DOI: 10.1038/nature05610
PubMed ID: 20682767
Title: An atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB-inducing kinase via Lys63-linked ubiquitination.
PubMed ID: 20682767
Sequence Information:
- Length: 947
- Mass: 104042
- Checksum: C9D10F67FF7F48AC
- Sequence:
MAVMEMACPG APGSAVGQQK ELPKAKEKTP PLGKKQSSVY KLEAVEKSPV FCGKWEILND VITKGTAKEG SEAGPAAISI IAQAECENSQ EFSPTFSERI FIAGSKQYSQ SESLDQIPNN VAHATEGKMA RVCWKGKRRS KARKKRKKKS SKSLAHAGVA LAKPLPRTPE QESCTIPVQE DESPLGAPYV RNTPQFTKPL KEPGLGQLCF KQLGEGLRPA LPRSELHKLI SPLQCLNHVW KLHHPQDGGP LPLPTHPFPY SRLPHPFPFH PLQPWKPHPL ESFLGKLACV DSQKPLPDPH LSKLACVDSP KPLPGPHLEP SCLSRGAHEK FSVEEYLVHA LQGSVSSGQA HSLTSLAKTW AARGSRSREP SPKTEDNEGV LLTEKLKPVD YEYREEVHWA THQLRLGRGS FGEVHRMEDK QTGFQCAVKK VRLEVFRAEE LMACAGLTSP RIVPLYGAVR EGPWVNIFME LLEGGSLGQL VKEQGCLPED RALYYLGQAL EGLEYLHSRR ILHGDVKADN VLLSSDGSHA ALCDFGHAVC LQPDGLGKSL LTGDYIPGTE THMAPEVVLG RSCDAKVDVW SSCCMMLHML NGCHPWTQFF RGPLCLKIAS EPPPVREIPP SCAPLTAQAI QEGLRKEPIH RVSAAELGGK VNRALQQVGG LKSPWRGEYK EPRHPPPNQA NYHQTLHAQP RELSPRAPGP RPAEETTGRA PKLQPPLPPE PPEPNKSPPL TLSKEESGMW EPLPLSSLEP APARNPSSPE RKATVPEQEL QQLEIELFLN SLSQPFSLEE QEQILSCLSI DSLSLSDDSE KNPSKASQSS RDTLSSGVHS WSSQAEARSS SWNMVLARGR PTDTPSYFNG VKVQIQSLNG EHLHIREFHR VKVGDIATGI SSQIPAAAFS LVTKDGQPVR YDMEVPDSGI DLQCTLAPDG SFAWSWRVKH GQLENRP
Genular Protein ID: 238365066
Symbol: Q68D39_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 433
- Mass: 47220
- Checksum: F9A8E975968AA0CA
- Sequence:
CFKQLGEGLR PALPRSELHK LISPLQCLNH VWKLHHPQDG GPLPLPTHPF PFHPLQPWKP HPLESFLGKL ACVDSQKPLP DPHLSKLACV DSPKPLPGPH LEPSCLSRGA HEKFSVEEYL VHALQGSVSS GQAHSLTSLA KTWAARGSRS RGPSPKTEDN EGVLLTEKLK PVDYEYREEV HWATHQLRLG RGSFGEVHRM EDKQTGFQCA VKKVRLEVFR AEELMACAGL TSPRIVPLYG AVREGPWVNI FMELLEGGSL GQLVKEQGCL PEDRALYYLG QALEGLEYLH SRRILHGDVK ADNVLLSSDG SHAALCDFGH AVCLQPDGLG KSLLTGDYIP GTETHMAPEV VLGRSCDAKV DVWSSCCMML HMLNGCHPWT QFFRGPLCLK VGDGTQHGQQ GELQGPGAQA AGWRGCSAVA DGARGGLVIH VGS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.