Details for: DGKQ

Gene ID: 1609

Symbol: DGKQ

Ensembl ID: ENSG00000145214

Description: diacylglycerol kinase theta

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 58.0539
    Cell Significance Index: -9.0300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 34.7732
    Cell Significance Index: -8.8200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 7.3563
    Cell Significance Index: -9.0700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.3914
    Cell Significance Index: -9.0900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 2.1179
    Cell Significance Index: -6.5100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.9582
    Cell Significance Index: 135.4200
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 1.5814
    Cell Significance Index: 26.0600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.3410
    Cell Significance Index: 1210.7900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.3068
    Cell Significance Index: -2.8600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.0184
    Cell Significance Index: 15.2600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9571
    Cell Significance Index: 104.1100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9348
    Cell Significance Index: 56.1200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.9286
    Cell Significance Index: 12.6700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8325
    Cell Significance Index: 135.4000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7719
    Cell Significance Index: 22.2400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7402
    Cell Significance Index: 33.5500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7269
    Cell Significance Index: 71.9100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.6804
    Cell Significance Index: 14.7400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.3778
    Cell Significance Index: 44.0300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3776
    Cell Significance Index: 261.1300
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.3444
    Cell Significance Index: 5.1900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3228
    Cell Significance Index: 64.7500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.3165
    Cell Significance Index: 11.1200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2466
    Cell Significance Index: 12.8100
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 0.2237
    Cell Significance Index: 2.3800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.2056
    Cell Significance Index: 4.4000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1977
    Cell Significance Index: 4.2100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.1862
    Cell Significance Index: 5.3100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1721
    Cell Significance Index: 4.8100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.1680
    Cell Significance Index: 6.3600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1585
    Cell Significance Index: 3.4700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.1542
    Cell Significance Index: 6.8200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1525
    Cell Significance Index: 54.7100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1313
    Cell Significance Index: 26.0500
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.1173
    Cell Significance Index: 1.6700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1107
    Cell Significance Index: 13.6100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1094
    Cell Significance Index: 19.7300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.1009
    Cell Significance Index: 1.0500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0776
    Cell Significance Index: 1.9400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0774
    Cell Significance Index: 5.0000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0743
    Cell Significance Index: 14.1400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0688
    Cell Significance Index: 3.2100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0651
    Cell Significance Index: 35.5300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0639
    Cell Significance Index: 4.3000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0556
    Cell Significance Index: 1.4900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0511
    Cell Significance Index: 1.0600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0495
    Cell Significance Index: 21.9000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0143
    Cell Significance Index: 1.9600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0018
    Cell Significance Index: 3.3100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0011
    Cell Significance Index: -2.1000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0012
    Cell Significance Index: -1.8800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0032
    Cell Significance Index: -4.3300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0043
    Cell Significance Index: -2.7200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0075
    Cell Significance Index: -0.2400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0099
    Cell Significance Index: -2.8400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0101
    Cell Significance Index: -7.4100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0107
    Cell Significance Index: -8.0700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0112
    Cell Significance Index: -8.2800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0113
    Cell Significance Index: -5.1400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0137
    Cell Significance Index: -2.3400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0151
    Cell Significance Index: -8.5200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0159
    Cell Significance Index: -1.2200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0165
    Cell Significance Index: -10.3300
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0165
    Cell Significance Index: -0.2200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0198
    Cell Significance Index: -2.8800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0248
    Cell Significance Index: -3.1800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0303
    Cell Significance Index: -3.4800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0307
    Cell Significance Index: -3.6200
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.0322
    Cell Significance Index: -0.2100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0384
    Cell Significance Index: -2.3600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0385
    Cell Significance Index: -0.6600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0409
    Cell Significance Index: -1.9200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0440
    Cell Significance Index: -3.1100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0447
    Cell Significance Index: -0.6400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0471
    Cell Significance Index: -9.9300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0508
    Cell Significance Index: -5.1900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0557
    Cell Significance Index: -7.2000
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.0734
    Cell Significance Index: -1.0300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0843
    Cell Significance Index: -8.7800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0874
    Cell Significance Index: -2.3800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0930
    Cell Significance Index: -6.9300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1057
    Cell Significance Index: -6.4800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1088
    Cell Significance Index: -8.6200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1111
    Cell Significance Index: -7.0000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1141
    Cell Significance Index: -6.4000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1159
    Cell Significance Index: -2.4600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1168
    Cell Significance Index: -6.1300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.1271
    Cell Significance Index: -1.1700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1347
    Cell Significance Index: -4.2900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1436
    Cell Significance Index: -4.7000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1471
    Cell Significance Index: -7.6600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1630
    Cell Significance Index: -5.7100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1644
    Cell Significance Index: -3.3000
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.1669
    Cell Significance Index: -2.3400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1699
    Cell Significance Index: -3.6700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1704
    Cell Significance Index: -4.3800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1710
    Cell Significance Index: -4.1000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1780
    Cell Significance Index: -3.5200
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.2017
    Cell Significance Index: -2.8900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2023
    Cell Significance Index: -5.8000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** DGKQ is a non-catalytic enzyme, meaning it does not directly catalyze the phosphorylation of diacylglycerol. Instead, it regulates the activity of other enzymes, such as protein kinase C (PKC), by phosphorylating and inhibiting them. DGKQ is also known to interact with various signaling molecules, including G-proteins, PKC, and transcription factors, thereby modulating their activity. Its expression is highly regulated, with changes in DGKQ levels affecting the phosphorylation state and activity of downstream targets. **Pathways and Functions** DGKQ is involved in several signaling pathways, including: 1. **G protein-coupled receptor signaling pathway**: DGKQ regulates the activity of PKC, which is activated by GPCRs, thereby modulating downstream signaling events. 2. **Protein kinase C signaling pathway**: DGKQ phosphorylates and inhibits PKC, regulating its activity and downstream effects. 3. **ATP-dependent diacylglycerol kinase activity**: DGKQ phosphorylates diacylglycerol, generating phosphatidic acid, which is involved in lipid metabolism and energy homeostasis. 4. **Metabolic regulation**: DGKQ regulates the activity of enzymes involved in lipid metabolism, including phospholipase D and phosphatidic acid phosphatase. 5. **Gene expression regulation**: DGKQ modulates the activity of transcription factors, including NF-κB and CREB, which regulate gene expression in response to various stimuli. **Clinical Significance** Aberrant expression or activity of DGKQ has been implicated in various diseases, including: 1. **Atherosclerosis**: DGKQ regulates lipid metabolism and inflammation, which are key factors in the development of atherosclerosis. 2. **Neurodegenerative disorders**: DGKQ modulates signaling pathways involved in neuronal survival and death, suggesting its potential role in neurodegenerative diseases, such as Alzheimer's and Parkinson's. 3. **Cancer**: DGKQ regulates cell growth and survival, which are key features of cancer cells, suggesting its potential as a therapeutic target. 4. **Inflammatory disorders**: DGKQ modulates the activity of immune cells, including macrophages and T cells, which are involved in inflammatory responses. In conclusion, DGKQ is a multifunctional enzyme involved in regulating various cellular processes, including lipid metabolism, signaling pathways, and gene expression. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into its role in human health and disease.

Genular Protein ID: 1625584070

Symbol: DGKQ_HUMAN

Name: Diglyceride kinase theta

UniProtKB Accession Codes:

P52824 Q6P3W4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 5 CTD 1 ChEBI 35 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EC 2 EMBL 3 Ensembl 1 ExpressionAtlas 1 GO 48 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 14 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7607687

Title: Chromosomal localization of three mouse diacylglycerol kinase (DAGK) genes: genes sharing sequence homology to the Drosophila retinal degeneration A (rdgA) gene.

PubMed ID: 7607687

DOI: 10.1016/0888-7543(95)80182-l

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9099683

Title: Cloning of a novel human diacylglycerol kinase (DGKtheta) containing three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain.

PubMed ID: 9099683

DOI: 10.1074/jbc.272.16.10422

PubMed ID: 10066731

Title: Diacylglycerol kinase theta binds to and is negatively regulated by active RhoA.

PubMed ID: 10066731

DOI: 10.1074/jbc.274.11.6820

PubMed ID: 11309392

Title: Nuclear diacylglycerol kinase-theta is activated in response to alpha-thrombin.

PubMed ID: 11309392

DOI: 10.1074/jbc.m101501200

PubMed ID: 12799190

Title: Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus.

PubMed ID: 12799190

DOI: 10.1016/s0014-4827(03)00115-0

PubMed ID: 15164764

Title: Structure-activity relationship of diacylglycerol kinase theta.

PubMed ID: 15164764

DOI: 10.1016/j.bbalip.2003.11.008

PubMed ID: 15632189

Title: Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C.

PubMed ID: 15632189

DOI: 10.1074/jbc.m409301200

PubMed ID: 17664281

Title: Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17.

PubMed ID: 17664281

DOI: 10.1128/mcb.00355-07

PubMed ID: 22627129

Title: Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.

PubMed ID: 22627129

DOI: 10.1016/j.bbrc.2012.05.077

PubMed ID: 23949095

Title: Evaluations of the selectivities of the diacylglycerol kinase inhibitors R59022 and R59949 among diacylglycerol kinase isozymes using a new non-radioactive assay method.

PubMed ID: 23949095

DOI: 10.1159/000351849

PubMed ID: 26748701

Title: DGKtheta Catalytic Activity Is Required for Efficient Recycling of Presynaptic Vesicles at Excitatory Synapses.

PubMed ID: 26748701

DOI: 10.1016/j.celrep.2015.12.022

Sequence Information:

  • Length: 942
  • Mass: 101155
  • Checksum: 836D4FCBC208A5B6
  • Sequence:
    • MAAAAEPGAR AWLGGGSPRP GSPACSPVLG SGGRARPGPG PGPGPERAGV RAPGPAAAPG 
HSFRKVTLTK PTFCHLCSDF IWGLAGFLCD VCNFMSHEKC LKHVRIPCTS VAPSLVRVPV 
AHCFGPRGLH KRKFCAVCRK VLEAPALHCE VCELHLHPDC VPFACSDCRQ CHQDGHQDHD 
THHHHWREGN LPSGARCEVC RKTCGSSDVL AGVRCEWCGV QAHSLCSAAL APECGFGRLR 
SLVLPPACVR LLPGGFSKTQ SFRIVEAAEP GEGGDGADGS AAVGPGRETQ ATPESGKQTL 
KIFDGDDAVR RSQFRLVTVS RLAGAEEVLE AALRAHHIPE DPGHLELCRL PPSSQACDAW 
AGGKAGSAVI SEEGRSPGSG EATPEAWVIR ALPRAQEVLK IYPGWLKVGV AYVSVRVTPK 
STARSVVLEV LPLLGRQAES PESFQLVEVA MGCRHVQRTM LMDEQPLLDR LQDIRQMSVR 
QVSQTRFYVA ESRDVAPHVS LFVGGLPPGL SPEEYSSLLH EAGATKATVV SVSHIYSSQG 
AVVLDVACFA EAERLYMLLK DMAVRGRLLT ALVLPDLLHA KLPPDSCPLL VFVNPKSGGL 
KGRDLLCSFR KLLNPHQVFD LTNGGPLPGL HLFSQVPCFR VLVCGGDGTV GWVLGALEET 
RYRLACPEPS VAILPLGTGN DLGRVLRWGA GYSGEDPFSV LLSVDEADAV LMDRWTILLD 
AHEAGSAEND TADAEPPKIV QMSNYCGIGI DAELSLDFHQ AREEEPGKFT SRLHNKGVYV 
RVGLQKISHS RSLHKQIRLQ VERQEVELPS IEGLIFINIP SWGSGADLWG SDSDTRFEKP 
RMDDGLLEVV GVTGVVHMGQ VQGGLRSGIR IAQGSYFRVT LLKATPVQVD GEPWVQAPGH 
MIISAAGPKV HMLRKAKQKP RRAGTTRDAR ADAAPAPESD PR

Genular Protein ID: 3096399434

Symbol: Q59FF7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59FF7

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 5 CTD 1 ChEBI 10 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 7 Gene3D 2 InterPro 9 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 7 PeptideAtlas 1 Pfam 4 RefSeq 1 Rhea 3 RuleBase 1 SAM 1 SMART 4 SUPFAM 3 UniPathway 1

Sequence Information:

  • Length: 885
  • Mass: 95694
  • Checksum: 0427DD04A1114EAF
  • Sequence:
    • AAAPVPPACS PAAAPGHSFR KVTLTKPTFC HLCSDFIWGL AGFLCDVCNF MSHEKCLKHV 
RIPCTSVAPS LVRVPVAHCF GPRGLHKRKF CAVCRKVLEA PALHCEVCEL HLHPDCVPFA 
CSDCRQCHQD GHQDHDTHHH HWREGNLPSG ARCEVCRKTC GSSDVLAGVR CEWCGVQAHS 
LCSAALAPEC GFGRLRSLVL PPACVRLLPG GFSKTQSFRI VEAAEPGEGG DGADGSAAVG 
PGRETQATPE SGKQTLKIFD GDDAVRRSQF RLVTVSRLAG AEEVLEAALR AHHIPEDPGH 
LELCRLPPSS QACDAWAGGK AGSAVISEEG RSPGSGEATP EAWVIRALPR AQEVLKIYPG 
WLKVGVAYVS VRVTPKSTAR SVVLEVLPLL GRQAESPESF QLVEVAMGCR HVQRTMLMDE 
QPLLDRLQDI RQMSVRQVSQ TRFYVAESRD VAPHVSLFVG GLPPGLSPEE YSSLLHEAGA 
TKGAVVLDVA CFAEAERLYM LLKDMAVRGR LLTALVLPDL LHAKLPPDSC PLLVFVNPKS 
GGLKGRDLLC SFRKLLNPHQ VFDLTNGGPL PGLHLFSQVP CFRVLVCGGD GTVGWVLGAL 
EETRYRLACP EPSVAILPLG TGNDLGRVLR WGAGYSGEDP FSVLLSVDEA DAVLMDRWTI 
LLDAHEAGSA ENDTADAEPP KIVQMSNYCG IGIDAELSLD FHQAREEEPG KFTSRLHNKG 
VYVRVGLQKI SHSRSLHKQI RLQVERQEVE LPSIEGLIFI NIPSWGSGAD LWGSDSDTRF 
EKPRMDDGLL EVVGVTGVVH MGQVQGGLRS GIRIAQGSYF RVTLLKATPV QVDGEPWVQA 
PGHMIISAAG PKVHMLRKAK QKPRRAGTTR DARADAAPAP ESDPR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.