Details for: DFFB

Gene ID: 1677

Symbol: DFFB

Ensembl ID: ENSG00000169598

Description: DNA fragmentation factor subunit beta

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 65.1258
    Cell Significance Index: -10.1300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 38.4004
    Cell Significance Index: -9.7400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 21.6858
    Cell Significance Index: -8.8100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 8.4675
    Cell Significance Index: -10.4400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.7404
    Cell Significance Index: -10.0200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.6558
    Cell Significance Index: -10.4800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.1675
    Cell Significance Index: 222.1900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.8215
    Cell Significance Index: 164.7900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.7114
    Cell Significance Index: 44.8400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6086
    Cell Significance Index: 60.2100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5877
    Cell Significance Index: 35.2800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.5733
    Cell Significance Index: 21.7100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5451
    Cell Significance Index: 24.1100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5110
    Cell Significance Index: 461.4300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4681
    Cell Significance Index: 167.8900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4594
    Cell Significance Index: 49.9700
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.4466
    Cell Significance Index: 7.3600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3965
    Cell Significance Index: 11.4300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3444
    Cell Significance Index: 56.0100
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.3112
    Cell Significance Index: 4.4600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2963
    Cell Significance Index: 6.4200
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.2923
    Cell Significance Index: 3.6300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2376
    Cell Significance Index: 47.1600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2343
    Cell Significance Index: 162.0700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1853
    Cell Significance Index: 8.4000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1521
    Cell Significance Index: 10.5200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1274
    Cell Significance Index: 2.7900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1268
    Cell Significance Index: 3.1700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1004
    Cell Significance Index: 6.7500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0900
    Cell Significance Index: 5.5300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0805
    Cell Significance Index: 6.1800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0756
    Cell Significance Index: 1.6100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0631
    Cell Significance Index: 7.3500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0548
    Cell Significance Index: 7.5300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0413
    Cell Significance Index: 1.1800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0404
    Cell Significance Index: 7.2800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0399
    Cell Significance Index: 75.1700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0377
    Cell Significance Index: 0.4500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0372
    Cell Significance Index: 20.3400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0350
    Cell Significance Index: 1.2300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0226
    Cell Significance Index: 1.4600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0139
    Cell Significance Index: 6.1300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0088
    Cell Significance Index: 5.5700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0064
    Cell Significance Index: 0.1800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0020
    Cell Significance Index: 3.7400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0017
    Cell Significance Index: 2.5900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0003
    Cell Significance Index: 0.1300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0013
    Cell Significance Index: -0.0600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0039
    Cell Significance Index: -5.3300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0054
    Cell Significance Index: -0.1300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0071
    Cell Significance Index: -1.0300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0100
    Cell Significance Index: -7.3500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0132
    Cell Significance Index: -9.9900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0134
    Cell Significance Index: -9.9300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0158
    Cell Significance Index: -2.7000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0176
    Cell Significance Index: -9.9000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0190
    Cell Significance Index: -11.8900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0196
    Cell Significance Index: -1.0200
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0260
    Cell Significance Index: -0.3700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0286
    Cell Significance Index: -3.6700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0290
    Cell Significance Index: -8.3300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.0334
    Cell Significance Index: -0.7200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0338
    Cell Significance Index: -4.1500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0346
    Cell Significance Index: -4.0800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0490
    Cell Significance Index: -1.0400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0495
    Cell Significance Index: -2.7800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0549
    Cell Significance Index: -0.9400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0557
    Cell Significance Index: -11.7300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0573
    Cell Significance Index: -6.5700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0637
    Cell Significance Index: -6.5100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0667
    Cell Significance Index: -4.7200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0754
    Cell Significance Index: -9.7400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0761
    Cell Significance Index: -1.0900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0765
    Cell Significance Index: -2.4500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0780
    Cell Significance Index: -8.1200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0833
    Cell Significance Index: -4.3800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0986
    Cell Significance Index: -6.0500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1128
    Cell Significance Index: -5.3000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1231
    Cell Significance Index: -9.7500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1243
    Cell Significance Index: -3.9600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1305
    Cell Significance Index: -2.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1324
    Cell Significance Index: -9.8700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1338
    Cell Significance Index: -2.8900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1360
    Cell Significance Index: -2.7300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1364
    Cell Significance Index: -3.6600
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.1372
    Cell Significance Index: -1.8300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1374
    Cell Significance Index: -6.9400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1375
    Cell Significance Index: -7.1600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1377
    Cell Significance Index: -3.5400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1420
    Cell Significance Index: -4.6500
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1636
    Cell Significance Index: -4.0800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1685
    Cell Significance Index: -2.8200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1747
    Cell Significance Index: -3.4100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1807
    Cell Significance Index: -6.3300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1874
    Cell Significance Index: -5.1000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1894
    Cell Significance Index: -6.5800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2059
    Cell Significance Index: -5.2600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.2085
    Cell Significance Index: -2.6000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2220
    Cell Significance Index: -6.5200
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.2262
    Cell Significance Index: -4.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **DFFB is a subunit of the DNA fragmentation factor complex**: DFFB is a key component of the DNA fragmentation factor complex, which is involved in the execution phase of apoptosis. 2. **Highly expressed in specific cell types**: DFFB is specifically expressed in near-projecting glutamatergic cortical neurons, corticothalamic-projecting glutamatergic cortical neurons, and kidney proximal straight tubule epithelial cells, indicating its importance in maintaining cellular function in these cell types. 3. **Involved in DNA fragmentation and apoptosis**: DFFB is involved in the cleavage of DNA into smaller fragments, a hallmark of apoptotic cell death. 4. **Regulates negative regulation of apoptotic DNA fragmentation**: DFFB plays a crucial role in regulating the negative regulation of apoptotic DNA fragmentation, suggesting its involvement in maintaining cellular homeostasis. **Pathways and Functions:** 1. **Apoptosis**: DFFB is involved in the execution phase of apoptosis, a process of programmed cell death that plays a vital role in maintaining tissue homeostasis and preventing disease. 2. **DNA fragmentation**: DFFB is involved in the cleavage of DNA into smaller fragments, a hallmark of apoptotic cell death. 3. **Negative regulation of apoptotic DNA fragmentation**: DFFB regulates the negative regulation of apoptotic DNA fragmentation, suggesting its involvement in maintaining cellular homeostasis. 4. **DNA endonuclease activity**: DFFB is involved in DNA endonuclease activity, a process that cleaves DNA into smaller fragments. **Clinical Significance:** 1. **Apoptosis-related disorders**: Dysregulation of DFFB has been implicated in various apoptosis-related disorders, including neurodegenerative diseases and cancer. 2. **Cancer therapy**: Targeting DFFB could provide a new therapeutic strategy for cancer treatment, as its dysregulation has been associated with cancer development and progression. 3. **Neurodegenerative diseases**: DFFB's role in regulating apoptosis suggests its potential involvement in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. 4. **Kidney disease**: DFFB's expression in kidney epithelial cells suggests its potential involvement in kidney disease, including chronic kidney disease and acute kidney injury. In conclusion, the DNA fragmentation factor subunit beta (DFFB) gene plays a crucial role in regulating apoptosis and maintaining cellular homeostasis. Its dysregulation has been implicated in various apoptosis-related disorders, including cancer and neurodegenerative diseases. Further research is needed to fully understand the mechanisms by which DFFB regulates apoptosis and to explore its potential therapeutic applications.

Genular Protein ID: 2790884205

Symbol: DFFB_HUMAN

Name: DNA fragmentation factor subunit beta

UniProtKB Accession Codes:

O76075 O60521 Q5SR22 Q9BYI4 Q9BYI5 Q9BYI6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DNASU 1 DisGeNET 1 EC 1 EMBL 9 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9671700

Title: The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis.

PubMed ID: 9671700

DOI: 10.1073/pnas.95.15.8461

PubMed ID: 9689044

Title: Molecular cloning and characterization of human caspase-activated DNase.

PubMed ID: 9689044

DOI: 10.1073/pnas.95.16.9123

PubMed ID: 9560346

Title: CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45.

PubMed ID: 9560346

DOI: 10.1016/s0960-9822(98)79298-x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14759258

Title: An unappreciated role for RNA surveillance.

PubMed ID: 14759258

DOI: 10.1186/gb-2004-5-2-r8

PubMed ID: 19882353

Title: Histone H1 subtype preferences of DFF40 and possible nuclear localization of DFF40/45 in normal and trichostatin A-treated NB4 leukemic cells.

PubMed ID: 19882353

DOI: 10.1007/s10495-009-0418-7

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 11371636

Title: Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45.

PubMed ID: 11371636

DOI: 10.1073/pnas.111145098

PubMed ID: 10830907

Title: Structure and mutation analysis of the gene encoding DNA fragmentation factor 40 (caspase-activated nuclease), a candidate neuroblastoma tumour suppressor gene.

PubMed ID: 10830907

DOI: 10.1007/s004390000257

Sequence Information:

  • Length: 338
  • Mass: 39110
  • Checksum: 0B0F3F8D91209389
  • Sequence:
    • MLQKPKSVKL RALRSPRKFG VAGRSCQEVL RKGCLRFQLP ERGSRLCLYE DGTELTEDYF 
PSVPDNAELV LLTLGQAWQG YVSDIRRFLS AFHEPQVGLI QAAQQLLCDE QAPQRQRLLA 
DLLHNVSQNI AAETRAEDPP WFEGLESRFQ SKSGYLRYSC ESRIRSYLRE VSSYPSTVGA 
EAQEEFLRVL GSMCQRLRSM QYNGSYFDRG AKGGSRLCTP EGWFSCQGPF DMDSCLSRHS 
INPYSNRESR ILFSTWNLDH IIEKKRTIIP TLVEAIKEQD GREVDWEYFY GLLFTSENLK 
LVHIVCHKKT THKLNCDPSR IYKPQTRLKR KQPVRKRQ

Genular Protein ID: 1468370969

Symbol: Q96P73_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96P73

Database IDs:

Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 3 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 4 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15147901

Title: Characterization of splice variants of human caspase-activated DNase with CIDE-N structure and function.

PubMed ID: 15147901

DOI: 10.1016/j.febslet.2004.04.050

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

  • Length: 115
  • Mass: 12849
  • Checksum: 4D59BFEE32424142
  • Sequence:
    • MLQKPKSVKL RALRSPRKFG VAGRSCQEVL RKGCLRFQLP ERGSRLCLYE DGTELTEDYF 
PSVPDNAELV LLTLGQAWQG CEWQGLWRCE RHQALPQCIS RATGGAHPGR PAAAV

Genular Protein ID: 420974129

Symbol: Q96P74_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96P74

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15147901

Title: Characterization of splice variants of human caspase-activated DNase with CIDE-N structure and function.

PubMed ID: 15147901

DOI: 10.1016/j.febslet.2004.04.050

Sequence Information:

  • Length: 110
  • Mass: 12106
  • Checksum: 34E72888A0F3B909
  • Sequence:
    • MLQKPKSVKL RALRSPRKFG VAGRSCQEVL RKGCLRFQLP ERGSRLCLYE DGTELTEDYF 
PSVPDNAELV LLTLGQAWQG CGRCERHQAL PQCISRATGG AHPGRPAAAV

Genular Protein ID: 1709566851

Symbol: Q96P72_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96P72

Database IDs:

Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 2 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15147901

Title: Characterization of splice variants of human caspase-activated DNase with CIDE-N structure and function.

PubMed ID: 15147901

DOI: 10.1016/j.febslet.2004.04.050

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

  • Length: 80
  • Mass: 9053
  • Checksum: 9EB6C9C0B35AE529
  • Sequence:
    • MLQKPKSVKL RALRSPRKFG VAGRSCQEVL RKGCLRFQLP ERGSRLCLYE DGTELTEDYF 
PSVPDNAELV LLTLGQAWQG

Genular Protein ID: 2419879726

Symbol: B4DZS0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DZS0

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 5 Gene3D 2 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SMART 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

  • Length: 362
  • Mass: 41956
  • Checksum: 4CC54106A612393B
  • Sequence:
    • MLQKPKSVKL RALRSPRKFG VAGRSCQEVL RKGCLRFQLP ERGSRLCLYE DGTELTEDYF 
PSVPDNAELV LLTLGQAWQG CEWQGLWRMC LLLDRHLLFV PLVADVSDIR RFLSAFHEPQ 
VGLIQAAQQL LCDEQAPQRQ RLLADLLHNV SQNIAAETRA EDPPWFEGLE SRFQSKSGYL 
RYSCESRIRS YLREVSSYPS TVGAEAQEEF LRVLGSMCQR LRSMQYNGSY FDRGAKGGSR 
LCTPEGWFSC QGPFDMDSCL SRHSINPYSN RESRILFSTW NLDHIIEKKR TIIPTLVEAI 
KEQDGREVDW EYFYGLLFTS ENLKLVHIVC HKKTTHKLNC DPSRIYKPQT RLKRKQPVRK 
RQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.