Details for: ENG

Gene ID: 2022

Symbol: ENG

Ensembl ID: ENSG00000106991

Description: endoglin

Associated with

  • Activin binding
    (GO:0048185)
  • Artery morphogenesis
    (GO:0048844)
  • Atrial cardiac muscle tissue morphogenesis
    (GO:0055009)
  • Atrioventricular canal morphogenesis
    (GO:1905222)
  • Bmp binding
    (GO:0036122)
  • Bmp signaling pathway
    (GO:0030509)
  • Bone development
    (GO:0060348)
  • Branching involved in blood vessel morphogenesis
    (GO:0001569)
  • Cardiac atrium morphogenesis
    (GO:0003209)
  • Cardiac ventricle morphogenesis
    (GO:0003208)
  • Cell adhesion
    (GO:0007155)
  • Cell migration
    (GO:0016477)
  • Cell migration involved in endocardial cushion formation
    (GO:0003273)
  • Cellular response to mechanical stimulus
    (GO:0071260)
  • Central nervous system vasculogenesis
    (GO:0022009)
  • Coreceptor activity
    (GO:0015026)
  • Dorsal aorta morphogenesis
    (GO:0035912)
  • Endocardial cushion morphogenesis
    (GO:0003203)
  • Endocardial cushion to mesenchymal transition
    (GO:0090500)
  • Endothelial microparticle
    (GO:0072563)
  • Epithelial to mesenchymal transition
    (GO:0001837)
  • Epithelial to mesenchymal transition involved in endocardial cushion formation
    (GO:0003198)
  • External side of plasma membrane
    (GO:0009897)
  • Extracellular matrix constituent secretion
    (GO:0070278)
  • Extracellular space
    (GO:0005615)
  • Focal adhesion
    (GO:0005925)
  • Galactose binding
    (GO:0005534)
  • Glycosaminoglycan binding
    (GO:0005539)
  • Heart looping
    (GO:0001947)
  • Identical protein binding
    (GO:0042802)
  • Negative regulation of cell migration
    (GO:0030336)
  • Negative regulation of gene expression
    (GO:0010629)
  • Nuclear body
    (GO:0016604)
  • Outflow tract septum morphogenesis
    (GO:0003148)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of angiogenesis
    (GO:0045766)
  • Positive regulation of bmp signaling pathway
    (GO:0030513)
  • Positive regulation of collagen biosynthetic process
    (GO:0032967)
  • Positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
    (GO:1905007)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051897)
  • Positive regulation of protein phosphorylation
    (GO:0001934)
  • Positive regulation of smad protein signal transduction
    (GO:0060391)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Positive regulation of vascular associated smooth muscle cell differentiation
    (GO:1905065)
  • Protein binding
    (GO:0005515)
  • Protein homodimerization activity
    (GO:0042803)
  • Receptor complex
    (GO:0043235)
  • Regulation of cardiac muscle cell apoptotic process
    (GO:0010665)
  • Regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
    (GO:1905310)
  • Regulation of cell proliferation involved in heart morphogenesis
    (GO:2000136)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transforming growth factor beta receptor signaling pathway
    (GO:0017015)
  • Response to xenobiotic stimulus
    (GO:0009410)
  • Signaling receptor activator activity
    (GO:0030546)
  • Smooth muscle tissue development
    (GO:0048745)
  • Sprouting angiogenesis
    (GO:0002040)
  • Transforming growth factor beta binding
    (GO:0050431)
  • Transforming growth factor beta receptor activity
    (GO:0005024)
  • Transforming growth factor beta receptor signaling pathway
    (GO:0007179)
  • Transmembrane signaling receptor activity
    (GO:0004888)
  • Type ii transforming growth factor beta receptor binding
    (GO:0005114)
  • Type i transforming growth factor beta receptor binding
    (GO:0034713)
  • Vascular associated smooth muscle cell development
    (GO:0097084)
  • Vasculogenesis
    (GO:0001570)
  • Venous blood vessel morphogenesis
    (GO:0048845)
  • Ventricular trabecula myocardium morphogenesis
    (GO:0003222)

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 7.28
    Marker Score: 4114
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 4.49
    Marker Score: 11401
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 3.33
    Marker Score: 4841
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 3.12
    Marker Score: 2682
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 2.98
    Marker Score: 4311
  • Cell Name: peritubular capillary endothelial cell (CL1001033)
    Fold Change: 2.96
    Marker Score: 688.5
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 2.55
    Marker Score: 5092
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.35
    Marker Score: 1404
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 2.25
    Marker Score: 2412
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 2.23
    Marker Score: 13570.5
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 2.12
    Marker Score: 2287
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.1
    Marker Score: 2000
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 2.09
    Marker Score: 508
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.95
    Marker Score: 3746
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 1.93
    Marker Score: 5043
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 1.9
    Marker Score: 1794
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: 1.9
    Marker Score: 404
  • Cell Name: glomerular endothelial cell (CL0002188)
    Fold Change: 1.82
    Marker Score: 461
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.77
    Marker Score: 7651
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.75
    Marker Score: 549
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.74
    Marker Score: 2941.5
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 1.7
    Marker Score: 1525
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 1.66
    Marker Score: 1671
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 1.65
    Marker Score: 455
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 1.64
    Marker Score: 1481
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 1.62
    Marker Score: 390
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 1.61
    Marker Score: 887
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 1.6
    Marker Score: 351
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 1.58
    Marker Score: 1121
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.57
    Marker Score: 40291
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168111
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 1.46
    Marker Score: 414
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 1.46
    Marker Score: 1667
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 1.45
    Marker Score: 603
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.41
    Marker Score: 15888
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 1.41
    Marker Score: 1516
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.37
    Marker Score: 2591
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 1.34
    Marker Score: 313
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 1.34
    Marker Score: 520
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.33
    Marker Score: 8634
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 1.32
    Marker Score: 658
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: 1.26
    Marker Score: 524
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 1.25
    Marker Score: 787.5
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 1.22
    Marker Score: 1443
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 1.21
    Marker Score: 1660
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.18
    Marker Score: 1358
  • Cell Name: vasa recta ascending limb cell (CL1001131)
    Fold Change: 1.13
    Marker Score: 298
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 1.12
    Marker Score: 1384.5
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 1.1
    Marker Score: 1691
  • Cell Name: trophoblast giant cell (CL0002488)
    Fold Change: 1.1
    Marker Score: 355
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.08
    Marker Score: 734
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.06
    Marker Score: 16576
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251726.5
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.03
    Marker Score: 2098
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 1.01
    Marker Score: 2622
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 1
    Marker Score: 226
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71745
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47970.5
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1
    Marker Score: 1003
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30399
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.97
    Marker Score: 698
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.97
    Marker Score: 973
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.95
    Marker Score: 488
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2406
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.94
    Marker Score: 442
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.93
    Marker Score: 581
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.93
    Marker Score: 619
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 0.92
    Marker Score: 1149
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.91
    Marker Score: 5191
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2717
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.9
    Marker Score: 5400
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.9
    Marker Score: 206
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.89
    Marker Score: 408
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 0.88
    Marker Score: 487
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.88
    Marker Score: 435
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.87
    Marker Score: 840
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.87
    Marker Score: 312
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5255
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.86
    Marker Score: 8752
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.81
    Marker Score: 618
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.8
    Marker Score: 389
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.8
    Marker Score: 599
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.79
    Marker Score: 315
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.78
    Marker Score: 3197
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.77
    Marker Score: 687
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.77
    Marker Score: 897
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.76
    Marker Score: 1233
  • Cell Name: pericyte (CL0000669)
    Fold Change: 0.75
    Marker Score: 436
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.75
    Marker Score: 356
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.74
    Marker Score: 239
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 0.74
    Marker Score: 210
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.74
    Marker Score: 3110.5
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.74
    Marker Score: 674
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.73
    Marker Score: 380
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.73
    Marker Score: 301.5
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.72
    Marker Score: 262
  • Cell Name: osteoblast (CL0000062)
    Fold Change: 0.72
    Marker Score: 386
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 0.71
    Marker Score: 1379
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.71
    Marker Score: 11353
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.7
    Marker Score: 780

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Other Information

**Key characteristics:** * Endogenous protein * Protein size: 120-150 amino acids * Located on chromosome 17p13.1 * Has one extracellular domain and three intracellular domains * Has a unique structure that allows it to bind to multiple proteins **Pathways and functions:** * Endoglin is involved in cell adhesion and migration by binding to extracellular matrix proteins and signaling through the integrin/beta-catenin signaling pathway. * It is also involved in the regulation of angiogenesis by binding to the transforming growth factor beta receptor (TGFR) and modulating its activity. * Endoglin has been shown to play a role in the development and progression of cancer. It is often overexpressed in cancer cells and is associated with poor prognosis. **Clinical significance:** * Mutations in the ENG gene have been linked to a number of human diseases, including cardiovascular disease, cancer, and diabetes. * Targeting ENG has been investigated as a therapeutic strategy for these diseases. * A number of small molecule inhibitors of ENG are currently being evaluated in clinical trials.

Genular Protein ID: 1620781284

Symbol: EGLN_HUMAN

Name: Endoglin

UniProtKB Accession Codes:

P17813 Q14248 Q14926 Q5T9C0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 14 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 75 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 4 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 3 PIR 1 PRO 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 3 SAM 1 SASBDB 1 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8370410

Title: Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions.

PubMed ID: 8370410

DOI: 10.1002/eji.1830230943

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 1692830

Title: Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells.

PubMed ID: 1692830

DOI: 10.1016/s0021-9258(19)38892-1

PubMed ID: 7894484

Title: Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1.

PubMed ID: 7894484

DOI: 10.1038/ng1294-345

PubMed ID: 1326540

Title: Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells.

PubMed ID: 1326540

DOI: 10.1016/s0021-9258(18)41732-2

PubMed ID: 16982625

Title: Identification of Tctex2beta, a novel dynein light chain family member that interacts with different transforming growth factor-beta receptors.

PubMed ID: 16982625

DOI: 10.1074/jbc.m608614200

PubMed ID: 17540773

Title: The interaction of endoglin with beta-arrestin2 regulates transforming growth factor-beta-mediated ERK activation and migration in endothelial cells.

PubMed ID: 17540773

DOI: 10.1074/jbc.m700176200

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 21737454

Title: Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth.

PubMed ID: 21737454

DOI: 10.1074/jbc.m111.260133

PubMed ID: 22347366

Title: Structural and functional insights into endoglin ligand recognition and binding.

PubMed ID: 22347366

DOI: 10.1371/journal.pone.0029948

PubMed ID: 23300529

Title: Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-endoglin antibodies.

PubMed ID: 23300529

DOI: 10.1371/journal.pone.0050920

PubMed ID: 28564608

Title: Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.

PubMed ID: 28564608

DOI: 10.1016/j.celrep.2017.05.011

PubMed ID: 9245986

Title: Characterization of endoglin and identification of novel mutations in hereditary hemorrhagic telangiectasia.

PubMed ID: 9245986

DOI: 10.1086/513906

PubMed ID: 9157574

Title: A novel missense mutation in the endoglin gene in hereditary hemorrhagic telangiectasia.

PubMed ID: 9157574

PubMed ID: 9554745

Title: Mutation and expression analysis of the endoglin gene in hereditary hemorrhagic telangiectasia reveals null alleles.

PubMed ID: 9554745

DOI: 10.1002/(sici)1098-1004(1998)11:4<286::aid-humu6>3.0.co;2-b

PubMed ID: 10545596

Title: Expression analysis of four endoglin missense mutations suggests that haploinsufficiency is the predominant mechanism for hereditary hemorrhagic telangiectasia type 1.

PubMed ID: 10545596

DOI: 10.1093/hmg/8.12.2171

PubMed ID: 10982033

Title: Two common endoglin mutations in families with hereditary hemorrhagic telangiectasia in the Netherlands Antilles: evidence for a founder effect.

PubMed ID: 10982033

DOI: 10.1007/s004390000326

PubMed ID: 10625079

Title: Identification of hereditary hemorrhagic telangiectasia type 1 in newborns by protein expression and mutation analysis of endoglin.

PubMed ID: 10625079

DOI: 10.1203/00006450-200001000-00008

PubMed ID: 15024723

Title: Molecular screening of ALK1/ACVRL1 and ENG genes in hereditary hemorrhagic telangiectasia in France.

PubMed ID: 15024723

DOI: 10.1002/humu.20017

PubMed ID: 15712270

Title: Hepatic manifestation is associated with ALK1 in hereditary hemorrhagic telangiectasia: identification of five novel ALK1 and one novel ENG mutations.

PubMed ID: 15712270

DOI: 10.1002/humu.9311

PubMed ID: 16752392

Title: Novel mutations in ENG and ACVRL1 identified in a series of 200 individuals undergoing clinical genetic testing for hereditary hemorrhagic telangiectasia (HHT): correlation of genotype with phenotype.

PubMed ID: 16752392

DOI: 10.1002/humu.20342

PubMed ID: 16525724

Title: Novel mutations in the ENG and ACVRL1 genes causing hereditary hemorrhagic teleangiectasia.

PubMed ID: 16525724

PubMed ID: 20414677

Title: Update on molecular diagnosis of hereditary hemorrhagic telangiectasia.

PubMed ID: 20414677

DOI: 10.1007/s00439-010-0825-4

Sequence Information:

  • Length: 658
  • Mass: 70578
  • Checksum: 49CA2CE013298D17
  • Sequence:
    • MDRGTLPLAV ALLLASCSLS PTSLAETVHC DLQPVGPERG EVTYTTSQVS KGCVAQAPNA 
ILEVHVLFLE FPTGPSQLEL TLQASKQNGT WPREVLLVLS VNSSVFLHLQ ALGIPLHLAY 
NSSLVTFQEP PGVNTTELPS FPKTQILEWA AERGPITSAA ELNDPQSILL RLGQAQGSLS 
FCMLEASQDM GRTLEWRPRT PALVRGCHLE GVAGHKEAHI LRVLPGHSAG PRTVTVKVEL 
SCAPGDLDAV LILQGPPYVS WLIDANHNMQ IWTTGEYSFK IFPEKNIRGF KLPDTPQGLL 
GEARMLNASI VASFVELPLA SIVSLHASSC GGRLQTSPAP IQTTPPKDTC SPELLMSLIQ 
TKCADDAMTL VLKKELVAHL KCTITGLTFW DPSCEAEDRG DKFVLRSAYS SCGMQVSASM 
ISNEAVVNIL SSSSPQRKKV HCLNMDSLSF QLGLYLSPHF LQASNTIEPG QQSFVQVRVS 
PSVSEFLLQL DSCHLDLGPE GGTVELIQGR AAKGNCVSLL SPSPEGDPRF SFLLHFYTVP 
IPKTGTLSCT VALRPKTGSQ DQEVHRTVFM RLNIISPDLS GCTSKGLVLP AVLGITFGAF 
LIGALLTAAL WYIYSHTRSP SKREPVVAVA APASSESSST NHSIGSTQST PCSTSSMA

Genular Protein ID: 3861710801

Symbol: Q96CG0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96CG0

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 GO 1 GenomeRNAi 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 RefSeq 2 SAM 3 SMR 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 658
  • Mass: 70636
  • Checksum: 724C2EE4981E2F9D
  • Sequence:
    • MDRGTLPLAV ALLLASCSLS PTSLAETVHC DLQPVGPERD EVTYTTSQVS KGCVAQAPNA 
ILEVHVLFLE FPTGPSQLEL TLQASKQNGT WPREVLLVLS VNSSVFLHLQ ALGIPLHLAY 
NSSLVTFQEP PGVNTTELPS FPKTQILEWA AERGPITSAA ELNDPQSILL RLGQAQGSLS 
FCMLEASQDM GRTLEWRPRT PALVRGCHLE GVAGHKEAHI LRVLPGHSAG PRTVTVKVEL 
SCAPGDLDAV LILQGPPYVS WLIDANHNMQ IWTTGEYSFK IFPEKNIRGF KLPDTPQGLL 
GEARMLNASI VASFVELPLA SIVSLHASSC GGRLQTSPAP IQTTPPKDTC SPELLMSLIQ 
TKCADDAMTL VLKKELVAHL KCTITGLTFW DPSCEAEDRG DKFVLRSAYS SCGMQVSASM 
ISNEAVVNIL SSSSPQRKKV HCLNMDSLSF QLGLYLSPHF LQASNTIEPG QQSFVQVRVS 
PSVSEFLLQL DSCHLDLGPE GGTVELIQGR AAKGNCVSLL SPSPEGDPRF SFLLHFYTVP 
IPKTGTLSCT VALRPKTGSQ DQEVHRTVFM RLNIISPDLS GCTSKGLVLP AVLGITFGAF 
LIGALLTAAL WYIYSHTRSP SKREPVVAVA APASSESSST NHSIGSTQST PCSTSSMA

Genular Protein ID: 2216601677

Symbol: B7Z6Y5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z6Y5

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 1 GenomeRNAi 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 RefSeq 1 SAM 2

Sequence Information:

  • Length: 476
  • Mass: 51154
  • Checksum: 6486B720226BF90C
  • Sequence:
    • MLEASQDMGR TLEWRPRTPA LVRGCHLEGV AGHKEAHILR VLPGHSAGPR TVTVKVELSC 
APGDLDAVLI LQGPPYVSWL IDANHNMQIW TTGEYSFKIF PEKNIRGFKL PDTPQGLLGE 
ARMLNASIVA SFLELPLASI VSLHASSCGG RLQTSPAPIQ TTPPKDTCSP ELLMSLIQTK 
CADDAMTLVL KKELVAHLKC TITGLTFWDP SCEAEDRGDK FVLRSAYSSC GMQVSASMIS 
NEAVVNILSS SSPQRKKVHC LNMDSLSFQL GLYLSPHFLQ ASNTIEPGQQ SFVQVRVSPS 
VSEFLLQLDS CHLDLGPEGG TVELIQGRAA KGNCVSLLSP SPEGDPRFSF LLHFYTVPIP 
KTGTLSCTVA LRPKTGSQDQ EVHRTVFMRL NIISPDLSGC TSKGLVLPAV LGITFGAFLI 
GALLTAALWY IYSHTRSPSK REPVVAVAAP ASSESSSTNH SIGSTQSTPC STSSMA

Genular Protein ID: 1165298801

Symbol: F5GX88_HUMAN

Name: N/A

UniProtKB Accession Codes:

F5GX88

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 2 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

Sequence Information:

  • Length: 476
  • Mass: 51140
  • Checksum: B4D81866E71F35F9
  • Sequence:
    • MLEASQDMGR TLEWRPRTPA LVRGCHLEGV AGHKEAHILR VLPGHSAGPR TVTVKVELSC 
APGDLDAVLI LQGPPYVSWL IDANHNMQIW TTGEYSFKIF PEKNIRGFKL PDTPQGLLGE 
ARMLNASIVA SFVELPLASI VSLHASSCGG RLQTSPAPIQ TTPPKDTCSP ELLMSLIQTK 
CADDAMTLVL KKELVAHLKC TITGLTFWDP SCEAEDRGDK FVLRSAYSSC GMQVSASMIS 
NEAVVNILSS SSPQRKKVHC LNMDSLSFQL GLYLSPHFLQ ASNTIEPGQQ SFVQVRVSPS 
VSEFLLQLDS CHLDLGPEGG TVELIQGRAA KGNCVSLLSP SPEGDPRFSF LLHFYTVPIP 
KTGTLSCTVA LRPKTGSQDQ EVHRTVFMRL NIISPDLSGC TSKGLVLPAV LGITFGAFLI 
GALLTAALWY IYSHTRSPSK REPVVAVAAP ASSESSSTNH SIGSTQSTPC STSSMA

Genular Protein ID: 1249722324

Symbol: Q5T9B9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5T9B9

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 ExpressionAtlas 1 GO 2 GenomeRNAi 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PharmGKB 1 RefSeq 1 SAM 2 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 625
  • Mass: 67542
  • Checksum: 8D8E510E5CB05812
  • Sequence:
    • MDRGTLPLAV ALLLASCSLS PTSLAETVHC DLQPVGPERG EVTYTTSQVS KGCVAQAPNA 
ILEVHVLFLE FPTGPSQLEL TLQASKQNGT WPREVLLVLS VNSSVFLHLQ ALGIPLHLAY 
NSSLVTFQEP PGVNTTELPS FPKTQILEWA AERGPITSAA ELNDPQSILL RLGQAQGSLS 
FCMLEASQDM GRTLEWRPRT PALVRGCHLE GVAGHKEAHI LRVLPGHSAG PRTVTVKVEL 
SCAPGDLDAV LILQGPPYVS WLIDANHNMQ IWTTGEYSFK IFPEKNIRGF KLPDTPQGLL 
GEARMLNASI VASFVELPLA SIVSLHASSC GGRLQTSPAP IQTTPPKDTC SPELLMSLIQ 
TKCADDAMTL VLKKELVAHL KCTITGLTFW DPSCEAEDRG DKFVLRSAYS SCGMQVSASM 
ISNEAVVNIL SSSSPQRKKV HCLNMDSLSF QLGLYLSPHF LQASNTIEPG QQSFVQVRVS 
PSVSEFLLQL DSCHLDLGPE GGTVELIQGR AAKGNCVSLL SPSPEGDPRF SFLLHFYTVP 
IPKTGTLSCT VALRPKTGSQ DQEVHRTVFM RLNIISPDLS GCTSKGLVLP AVLGITFGAF 
LIGALLTAAL WYIYSHTREY PRPPQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.