Details for: EPHB6

Gene ID: 2051

Symbol: EPHB6

Ensembl ID: ENSG00000106123

Description: EPH receptor B6

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 123.5653
    Cell Significance Index: -19.2200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 69.4282
    Cell Significance Index: -17.6100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 43.2938
    Cell Significance Index: -20.4400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 38.8424
    Cell Significance Index: -15.7800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.8481
    Cell Significance Index: -19.5400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.4845
    Cell Significance Index: -20.0500
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 5.9437
    Cell Significance Index: 13.4000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.9746
    Cell Significance Index: -19.6300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.7014
    Cell Significance Index: -14.4400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.6286
    Cell Significance Index: 115.1800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.5991
    Cell Significance Index: 707.0000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.5563
    Cell Significance Index: 312.1900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.3176
    Cell Significance Index: 58.2800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.2840
    Cell Significance Index: 48.6200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.1564
    Cell Significance Index: 60.0700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.9132
    Cell Significance Index: 12.4600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.8393
    Cell Significance Index: 26.8800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.7827
    Cell Significance Index: 21.3100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5446
    Cell Significance Index: 66.9600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5011
    Cell Significance Index: 14.0100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4667
    Cell Significance Index: 84.1400
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.4272
    Cell Significance Index: 6.6100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3737
    Cell Significance Index: 71.1100
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.2643
    Cell Significance Index: 2.2200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1878
    Cell Significance Index: 169.5900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1723
    Cell Significance Index: 23.6600
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.1552
    Cell Significance Index: 2.0700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1494
    Cell Significance Index: 14.7800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0885
    Cell Significance Index: 10.3100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0836
    Cell Significance Index: 57.8000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0742
    Cell Significance Index: 12.0800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0502
    Cell Significance Index: 18.0100
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.0484
    Cell Significance Index: 0.5000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0335
    Cell Significance Index: 2.1600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0012
    Cell Significance Index: -2.2400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0109
    Cell Significance Index: -0.6700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0125
    Cell Significance Index: -22.9700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0138
    Cell Significance Index: -21.2200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0154
    Cell Significance Index: -11.3000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0156
    Cell Significance Index: -1.7000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0188
    Cell Significance Index: -11.9700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0191
    Cell Significance Index: -0.6700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0191
    Cell Significance Index: -25.9500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0204
    Cell Significance Index: -2.6200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0230
    Cell Significance Index: -2.6300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0250
    Cell Significance Index: -18.9000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0253
    Cell Significance Index: -0.5000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0259
    Cell Significance Index: -0.7500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0266
    Cell Significance Index: -1.2400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0305
    Cell Significance Index: -4.4300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0315
    Cell Significance Index: -23.3000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0336
    Cell Significance Index: -18.3400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0382
    Cell Significance Index: -1.9300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0412
    Cell Significance Index: -23.2500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0446
    Cell Significance Index: -20.2500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0467
    Cell Significance Index: -7.9800
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: -0.0493
    Cell Significance Index: -0.3100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0600
    Cell Significance Index: -1.5000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0687
    Cell Significance Index: -19.7800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0719
    Cell Significance Index: -3.2600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0739
    Cell Significance Index: -1.6000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0775
    Cell Significance Index: -1.9800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0814
    Cell Significance Index: -8.3100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0839
    Cell Significance Index: -1.7800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0924
    Cell Significance Index: -18.3300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1014
    Cell Significance Index: -7.0100
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.1034
    Cell Significance Index: -1.4500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1079
    Cell Significance Index: -5.6700
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.1094
    Cell Significance Index: -1.5400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1135
    Cell Significance Index: -23.9000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1246
    Cell Significance Index: -2.0900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1372
    Cell Significance Index: -17.7200
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.1387
    Cell Significance Index: -2.2000
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1407
    Cell Significance Index: -3.2500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1431
    Cell Significance Index: -16.8800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.1448
    Cell Significance Index: -8.6900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1480
    Cell Significance Index: -2.1200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1548
    Cell Significance Index: -4.9300
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.1560
    Cell Significance Index: -1.2000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.1689
    Cell Significance Index: -1.5600
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1832
    Cell Significance Index: -7.5100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1873
    Cell Significance Index: -19.5000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1920
    Cell Significance Index: -14.3100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1940
    Cell Significance Index: -4.0600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2138
    Cell Significance Index: -12.0000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2241
    Cell Significance Index: -17.7500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.2241
    Cell Significance Index: -2.7800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2451
    Cell Significance Index: -15.4500
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2663
    Cell Significance Index: -11.5800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2680
    Cell Significance Index: -5.7900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2682
    Cell Significance Index: -8.7800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2815
    Cell Significance Index: -9.8600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2936
    Cell Significance Index: -6.0900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2971
    Cell Significance Index: -13.9600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3022
    Cell Significance Index: -23.1900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3042
    Cell Significance Index: -8.0000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3047
    Cell Significance Index: -15.8700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3301
    Cell Significance Index: -11.4700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.3676
    Cell Significance Index: -4.0100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.4245
    Cell Significance Index: -6.8100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** The EPHB6 gene encodes a receptor with an extracellular domain, a transmembrane domain, and an intracellular domain, which interacts with ephrin ligands to regulate cellular behavior. 2. **Ligand Binding:** EPHB6 binds to ephrin ligands, which activate the receptor and trigger downstream signaling pathways. 3. **Signaling Pathways:** The ephrin signaling pathway involves multiple signaling cascades, including the activation of tyrosine kinases, phospholipase C, and MAP kinases, which regulate various cellular processes. 4. **Cellular Expression:** EPHB6 is expressed in a range of cell types, including pancreatic ductal cells, Mueller cells, and neurons, indicating its involvement in different tissues and developmental stages. **Pathways and Functions:** 1. **Axon Guidance:** EPHB6 plays a crucial role in axon guidance, regulating the growth and branching of axons during neural development. 2. **Nervous System Development:** The ephrin signaling pathway, involving EPHB6, is essential for the development and patterning of the nervous system. 3. **Cell Repulsion:** EPHB6 promotes cell repulsion, preventing cells from coming into contact with each other and regulating tissue patterning. 4. **Neurotransmission:** The ephrin signaling pathway, involving EPHB6, regulates neurotransmission and synaptic plasticity in the nervous system. **Clinical Significance:** Dysregulation of the ephrin signaling pathway, involving EPHB6, has been implicated in various neurological and developmental disorders, including: 1. **Neurodegenerative diseases:** Altered ephrin signaling has been linked to neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. 2. **Developmental disorders:** Dysregulation of ephrin signaling has been implicated in developmental disorders, such as autism and schizophrenia. 3. **Cancer:** Ephrin signaling, involving EPHB6, has been shown to play a role in cancer development and progression. In conclusion, the EPHB6 gene plays a crucial role in the regulation of cellular behavior and development through the ephrin signaling pathway. Its dysregulation has been implicated in various neurological and developmental disorders, highlighting the importance of further research into the mechanisms of ephrin signaling and its clinical applications.

Genular Protein ID: 538486877

Symbol: EPHB6_HUMAN

Name: Ephrin type-B receptor 6

UniProtKB Accession Codes:

O15197 A4D2I7 A8CDT5 D3DXD3 Q2TB23 Q2TB24

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CDD 3 CPTAC 1 CTD 1 ChEBI 1 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EMBL 13 GO 10 Gene3D 6 GeneCards 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 InParanoid 1 IntAct 1 InterPro 16 KEGG 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PIRSF 1 PRINTS 2 PRO 1 PROSITE 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 4 RefSeq 2 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 5 SignaLink 1 TreeFam 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9207182

Title: Expression of a kinase-defective Eph-like receptor in the normal human brain.

PubMed ID: 9207182

DOI: 10.1006/bbrc.1997.6812

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18425388

Title: Identification of EphB6 variant-derived epitope peptides recognized by cytotoxic T-lymphocytes from HLA-A24+ malignant glioma patients.

PubMed ID: 18425388

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 11713248

Title: The kinase-null EphB6 receptor undergoes transphosphorylation in a complex with EphB1.

PubMed ID: 11713248

DOI: 10.1074/jbc.m108011200

PubMed ID: 12517763

Title: The EphB6 receptor inhibits JNK activation in T lymphocytes and modulates T cell receptor-mediated responses.

PubMed ID: 12517763

DOI: 10.1074/jbc.m208179200

PubMed ID: 15955811

Title: Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration.

PubMed ID: 15955811

DOI: 10.1074/jbc.m500010200

PubMed ID: 18754880

Title: Erythropoietin-producing hepatocyte B6 variant-derived peptides with the ability to induce glioma-reactive cytotoxic T lymphocytes in human leukocyte antigen-A2+ glioma patients.

PubMed ID: 18754880

DOI: 10.1111/j.1349-7006.2008.00866.x

PubMed ID: 19234485

Title: EphB6 receptor significantly alters invasiveness and other phenotypic characteristics of human breast carcinoma cells.

PubMed ID: 19234485

DOI: 10.1038/onc.2009.18

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 1021
  • Mass: 110700
  • Checksum: BF1D4D9BE34358A5
  • Sequence:
    • MATEGAAQLG NRVAGMVCSL WVLLLVSSVL ALEEVLLDTT GETSEIGWLT YPPGGWDEVS 
VLDDQRRLTR TFEACHVAGA PPGTGQDNWL QTHFVERRGA QRAHIRLHFS VRACSSLGVS 
GGTCRETFTL YYRQAEEPDS PDSVSSWHLK RWTKVDTIAA DESFPSSSSS SSSSSSAAWA 
VGPHGAGQRA GLQLNVKERS FGPLTQRGFY VAFQDTGACL ALVAVRLFSY TCPAVLRSFA 
SFPETQASGA GGASLVAAVG TCVAHAEPEE DGVGGQAGGS PPRLHCNGEG KWMVAVGGCR 
CQPGYQPARG DKACQACPRG LYKSSAGNAP CSPCPARSHA PNPAAPVCPC LEGFYRASSD 
PPEAPCTGPP SAPQELWFEV QGSALMLHWR LPRELGGRGD LLFNVVCKEC EGRQEPASGG 
GGTCHRCRDE VHFDPRQRGL TESRVLVGGL RAHVPYILEV QAVNGVSELS PDPPQAAAIN 
VSTSHEVPSA VPVVHQVSRA SNSITVSWPQ PDQTNGNILD YQLRYYDQAE DESHSFTLTS 
ETNTATVTQL SPGHIYGFQV RARTAAGHGP YGGKVYFQTL PQGELSSQLP ERLSLVIGSI 
LGALAFLLLA AITVLAVVFQ RKRRGTGYTE QLQQYSSPGL GVKYYIDPST YEDPCQAIRE 
LAREVDPAYI KIEEVIGTGS FGEVRQGRLQ PRGRREQTVA IQALWAGGAE SLQMTFLGRA 
AVLGQFQHPN ILRLEGVVTK SRPLMVLTEF MELGPLDSFL RQREGQFSSL QLVAMQRGVA 
AAMQYLSSFA FVHRSLSAHS VLVNSHLVCK VARLGHSPQG PSCLLRWAAP EVIAHGKHTT 
SSDVWSFGIL MWEVMSYGER PYWDMSEQEV LNAIEQEFRL PPPPGCPPGL HLLMLDTWQK 
DRARRPHFDQ LVAAFDKMIR KPDTLQAGGD PGERPSQALL TPVALDFPCL DSPQAWLSAI 
GLECYQDNFS KFGLCTFSDV AQLSLEDLPA LGITLAGHQK KLLHHIQLLQ QHLRQQGSVE 
V

Genular Protein ID: 681707333

Symbol: F8WCM8_HUMAN

Name: N/A

UniProtKB Accession Codes:

F8WCM8

Database IDs:

ARBA 8 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 4 GO 7 Gene3D 6 GeneTree 1 HGNC 1 InterPro 16 KEGG 1 MANE-Select 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 2 PRINTS 2 PROSITE 10 PeptideAtlas 1 Pfam 6 Proteomes 2 ProteomicsDB 2 RefSeq 4 SAM 3 SMART 4 SUPFAM 5 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 1022
  • Mass: 110771
  • Checksum: 5038EA11DEE6FFCE
  • Sequence:
    • MATEGAAQLG NRVAGMVCSL WVLLLVSSVL ALEEVLLDTT GETSEIGWLT YPPGGWDEVS 
VLDDQRRLTR TFEACHVAGA PPGTGQDNWL QTHFVERRGA QRAHIRLHFS VRACSSLGVS 
GGTCRETFTL YYRQAEEPDS PDSVSSWHLK RWTKVDTIAA DESFPSSSSS SSSSSSSAAW 
AVGPHGAGQR AGLQLNVKER SFGPLTQRGF YVAFQDTGAC LALVAVRLFS YTCPAVLRSF 
ASFPETQASG AGGASLVAAV GTCVAHAEPE EDGVGGQAGG SPPRLHCNGE GKWMVAVGGC 
RCQPGYQPAR GDKACQACPR GLYKASAGNA PCSPCPARSH APNPAAPVCP CLEGFYRASS 
DPPEAPCTGP PSAPQELWFE VQGSALMLHW RLPRELGGRG DLLFNVVCKE CEGRQEPASG 
GGGTCHRCRD EVHFDPRQRG LTESRVLVGG LRAHVPYILE VQAVNGVSEL SPDPPQAAAI 
NVSTSHEVPS AVPVVHQVSR ASNSITVSWP QPDQTNGNIL DYQLRYYDQA EDESHSFTLT 
SETNTATVTQ LSPGHIYGFQ VRARTAAGHG PYGGKVYFQT LPQGELSSQL PERLSLVIGS 
ILGALAFLLL AAITVLAVVF QRKRRGTGYT EQLQQYSSPG LGVKYYIDPS TYEDPCQAIR 
ELAREVDPAY IKIEEVIGTG SFGEVRQGRL QPRGRREQTV AIQALWAGGA ESLQMTFLGR 
AAVLGQFQHP NILRLEGVVT KSRPLMVLTE FMELGPLDSF LRQREGQFSS LQLVAMQRGV 
AAAMQYLSSF AFVHRSLSAH SVLVNSHLVC KVARLGHSPQ GPSCLLRWAA PEVIAHGKHT 
TSSDVWSFGI LMWEVMSYGE RPYWDMSEQE VLNAIEQEFR LPPPPGCPPG LHLLMLDTWQ 
KDRARRPHFD QLVAAFDKMI RKPDTLQAGG DPGERPSQAL LTPVALDFPC LDSPQAWLSA 
IGLECYQDNF SKFGLCTFSD VAQLSLEDLP ALGITLAGHQ KKLLHHIQLL QQHLRQQGSV 
EV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.