Details for: FAAH
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 96.4993
Cell Significance Index: -15.0100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 57.0092
Cell Significance Index: -14.4600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 30.0549
Cell Significance Index: -12.2100 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 21.4822
Cell Significance Index: -14.4200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 12.7731
Cell Significance Index: -12.2000 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 12.3362
Cell Significance Index: -15.2100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 5.4874
Cell Significance Index: -14.7000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 3.8722
Cell Significance Index: -15.2800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 2.0254
Cell Significance Index: 329.4200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 1.9967
Cell Significance Index: -4.3700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.7872
Cell Significance Index: 38.7200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.7522
Cell Significance Index: 79.4200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.6601
Cell Significance Index: 47.8300 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.3247
Cell Significance Index: 19.8500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.3002
Cell Significance Index: 141.4200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.2601
Cell Significance Index: 75.6500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.1371
Cell Significance Index: 59.0700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.9440
Cell Significance Index: 12.8800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.8307
Cell Significance Index: 22.6100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.7128
Cell Significance Index: 19.9200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.7041
Cell Significance Index: 48.6900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.6295
Cell Significance Index: 126.2700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.6123
Cell Significance Index: 28.5500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.5826
Cell Significance Index: 67.8900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.5042
Cell Significance Index: 31.7800 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.4192
Cell Significance Index: 3.8600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.4157
Cell Significance Index: 74.9300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.4135
Cell Significance Index: 11.8000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.4059
Cell Significance Index: 13.0000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3830
Cell Significance Index: 47.1000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.3728
Cell Significance Index: 24.0500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.3703
Cell Significance Index: 16.3800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.3601
Cell Significance Index: 26.8400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.3356
Cell Significance Index: 12.7100 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.3314
Cell Significance Index: 3.4300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2666
Cell Significance Index: 50.7400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2548
Cell Significance Index: 91.3800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.2527
Cell Significance Index: 16.9900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.2398
Cell Significance Index: 5.2500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2265
Cell Significance Index: 22.4100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1705
Cell Significance Index: 5.9900 - Cell Name: epidermal cell (CL0000362)
Fold Change: 0.1686
Cell Significance Index: 0.3800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.1557
Cell Significance Index: 30.9000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1435
Cell Significance Index: 78.3600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.1254
Cell Significance Index: 2.6700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.1204
Cell Significance Index: 185.3500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1193
Cell Significance Index: 107.7100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.1181
Cell Significance Index: 3.1600 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0974
Cell Significance Index: 2.6100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0847
Cell Significance Index: 37.4500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0795
Cell Significance Index: 108.1500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0753
Cell Significance Index: 138.7900 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 0.0736
Cell Significance Index: 0.4800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0378
Cell Significance Index: 6.4500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0280
Cell Significance Index: 0.4800 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0108
Cell Significance Index: 1.4000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0016
Cell Significance Index: -2.9200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0029
Cell Significance Index: -1.8200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0044
Cell Significance Index: -0.3100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0056
Cell Significance Index: -4.2500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0062
Cell Significance Index: -4.5300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0119
Cell Significance Index: -1.3700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0182
Cell Significance Index: -13.5000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0192
Cell Significance Index: -2.7900 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0200
Cell Significance Index: -2.5700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0241
Cell Significance Index: -13.5900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0249
Cell Significance Index: -11.3000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0251
Cell Significance Index: -1.5400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0270
Cell Significance Index: -16.8300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0305
Cell Significance Index: -3.1200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0432
Cell Significance Index: -5.9300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0446
Cell Significance Index: -12.8400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.0505
Cell Significance Index: -0.8500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0645
Cell Significance Index: -3.3600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0781
Cell Significance Index: -16.4500 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -0.0909
Cell Significance Index: -1.1700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0947
Cell Significance Index: -9.8600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1002
Cell Significance Index: -11.8200 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: -0.1112
Cell Significance Index: -0.8500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.1152
Cell Significance Index: -2.8800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1341
Cell Significance Index: -7.0400 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1361
Cell Significance Index: -3.5800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1372
Cell Significance Index: -6.4500 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1448
Cell Significance Index: -3.7000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1451
Cell Significance Index: -11.1400 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1569
Cell Significance Index: -9.6200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1629
Cell Significance Index: -12.9000 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1702
Cell Significance Index: -3.5300 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.1748
Cell Significance Index: -2.5800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1824
Cell Significance Index: -6.3400 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.1918
Cell Significance Index: -1.9900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1985
Cell Significance Index: -11.1400 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.2013
Cell Significance Index: -2.4000 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.2129
Cell Significance Index: -2.3200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2644
Cell Significance Index: -7.0600 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2756
Cell Significance Index: -6.6100 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.2805
Cell Significance Index: -6.0000 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.2977
Cell Significance Index: -4.2300 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3130
Cell Significance Index: -9.9700 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3164
Cell Significance Index: -9.3200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4105601799
Symbol: FAAH1_HUMAN
Name: Fatty-acid amide hydrolase 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9122178
Title: Molecular characterization of human and mouse fatty acid amide hydrolases.
PubMed ID: 9122178
PubMed ID: 9878243
Title: Conserved chromosomal location and genomic structure of human and mouse fatty-acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation.
PubMed ID: 9878243
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12665801
Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
PubMed ID: 12665801
DOI: 10.1038/nbt810
PubMed ID: 17015445
Title: A second fatty acid amide hydrolase with variable distribution among placental mammals.
PubMed ID: 17015445
PubMed ID: 21049984
Title: Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2.
PubMed ID: 21049984
DOI: 10.1021/tx1002194
PubMed ID: 19926788
Title: Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2.
PubMed ID: 19926788
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 12060782
Title: A missense mutation in human fatty acid amide hydrolase associated with problem drug use.
PubMed ID: 12060782
PubMed ID: 15254019
Title: Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: evidence for a link between defects in the endocannabinoid system and problem drug use.
PubMed ID: 15254019
DOI: 10.1093/hmg/ddh216
PubMed ID: 16972078
Title: The fatty acid amide hydrolase 385 A/A (P129T) variant: haplotype analysis of an ancient missense mutation and validation of risk for drug addiction.
PubMed ID: 16972078
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 23556448
Title: Association of a functional FAAH polymorphism with methamphetamine-induced symptoms and dependence in a Malaysian population.
PubMed ID: 23556448
DOI: 10.2217/pgs.13.25
Sequence Information:
- Length: 579
- Mass: 63066
- Checksum: 633A92DC36940C18
- Sequence:
MVQYELWAAL PGASGVALAC CFVAAAVALR WSGRRTARGA VVRARQRQRA GLENMDRAAQ RFRLQNPDLD SEALLALPLP QLVQKLHSRE LAPEAVLFTY VGKAWEVNKG TNCVTSYLAD CETQLSQAPR QGLLYGVPVS LKECFTYKGQ DSTLGLSLNE GVPAECDSVV VHVLKLQGAV PFVHTNVPQS MFSYDCSNPL FGQTVNPWKS SKSPGGSSGG EGALIGSGGS PLGLGTDIGG SIRFPSSFCG ICGLKPTGNR LSKSGLKGCV YGQEAVRLSV GPMARDVESL ALCLRALLCE DMFRLDPTVP PLPFREEVYT SSQPLRVGYY ETDNYTMPSP AMRRAVLETK QSLEAAGHTL VPFLPSNIPH ALETLSTGGL FSDGGHTFLQ NFKGDFVDPC LGDLVSILKL PQWLKGLLAF LVKPLLPRLS AFLSNMKSRS AGKLWELQHE IEVYRKTVIA QWRALDLDVV LTPMLAPALD LNAPGRATGA VSYTMLYNCL DFPAGVVPVT TVTAEDEAQM EHYRGYFGDI WDKMLQKGMK KSVGLPVAVQ CVALPWQEEL CLRFMREVER LMTPEKQSS
Genular Protein ID: 3791554701
Symbol: Q9UG55_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 151
- Mass: 16894
- Checksum: D16F7383BADA4B4D
- Sequence:
RRQHPLPLLL LRHLRPQAHR EPPQVYTSSQ PLRVGYYETD NYTMPSPAMR RAVLETKQSL EAAGHTLVPF LPSNIPHALE TLSTGGLFSD GGHTFLQNFK GDFVDPCLGD LVSILKLPQW LKGLLAFLVK PLLPRLSAFL SNMKSRCTAK P
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.