Details for: FKTN

Gene ID: 2218

Symbol: FKTN

Ensembl ID: ENSG00000106692

Description: fukutin

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 172.1043
    Cell Significance Index: -26.7700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 102.6244
    Cell Significance Index: -26.0300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 56.8920
    Cell Significance Index: -26.8600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 51.9622
    Cell Significance Index: -21.1100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 22.1840
    Cell Significance Index: -21.1800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 21.8094
    Cell Significance Index: -26.8900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.9333
    Cell Significance Index: -26.6100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.8322
    Cell Significance Index: -26.9600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.6158
    Cell Significance Index: -20.3200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.9438
    Cell Significance Index: -10.8200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 2.4250
    Cell Significance Index: 461.4900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.5317
    Cell Significance Index: 307.2500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.0122
    Cell Significance Index: 363.0600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.9992
    Cell Significance Index: 56.0700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.9981
    Cell Significance Index: 37.8000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.9962
    Cell Significance Index: 197.6900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.9550
    Cell Significance Index: 42.2400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9297
    Cell Significance Index: 839.4800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.7993
    Cell Significance Index: 53.7500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.7725
    Cell Significance Index: 47.4800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.7625
    Cell Significance Index: 48.0600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.7389
    Cell Significance Index: 16.1800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.7077
    Cell Significance Index: 489.4700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6932
    Cell Significance Index: 75.4000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6839
    Cell Significance Index: 111.2300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.6761
    Cell Significance Index: 16.2200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.6676
    Cell Significance Index: 13.0300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.6469
    Cell Significance Index: 49.6500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5583
    Cell Significance Index: 33.5200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.5057
    Cell Significance Index: 7.6200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3808
    Cell Significance Index: 8.2500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2983
    Cell Significance Index: 20.6300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2748
    Cell Significance Index: 6.8700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2657
    Cell Significance Index: 47.9100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2142
    Cell Significance Index: 9.7100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2090
    Cell Significance Index: 5.8400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.1738
    Cell Significance Index: 4.9600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1579
    Cell Significance Index: 4.5500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1179
    Cell Significance Index: 64.4100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.1153
    Cell Significance Index: 2.4700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0818
    Cell Significance Index: 125.9500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0781
    Cell Significance Index: 10.7200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0743
    Cell Significance Index: 137.0600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0668
    Cell Significance Index: 125.7600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0592
    Cell Significance Index: 26.1800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0570
    Cell Significance Index: 7.0100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0461
    Cell Significance Index: 0.7900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0428
    Cell Significance Index: 1.1000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0381
    Cell Significance Index: 24.2100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0337
    Cell Significance Index: 45.7700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0330
    Cell Significance Index: 1.1600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0274
    Cell Significance Index: 12.4500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0155
    Cell Significance Index: 0.4200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0133
    Cell Significance Index: 0.6200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0101
    Cell Significance Index: -0.1300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0187
    Cell Significance Index: -0.9700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0206
    Cell Significance Index: -3.0000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0207
    Cell Significance Index: -15.1900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0302
    Cell Significance Index: -22.3700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0357
    Cell Significance Index: -27.0100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0447
    Cell Significance Index: -25.2400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0467
    Cell Significance Index: -0.6700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0480
    Cell Significance Index: -29.9800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0502
    Cell Significance Index: -8.5800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0774
    Cell Significance Index: -22.2800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0959
    Cell Significance Index: -12.3000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1105
    Cell Significance Index: -12.8800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1183
    Cell Significance Index: -1.4100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1285
    Cell Significance Index: -13.1300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1355
    Cell Significance Index: -28.5400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1516
    Cell Significance Index: -7.9000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1578
    Cell Significance Index: -11.1600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1653
    Cell Significance Index: -19.4900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1687
    Cell Significance Index: -21.7900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1748
    Cell Significance Index: -20.0300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2026
    Cell Significance Index: -21.1000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2153
    Cell Significance Index: -4.5700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2194
    Cell Significance Index: -10.3100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2341
    Cell Significance Index: -15.1100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2566
    Cell Significance Index: -8.2200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2698
    Cell Significance Index: -16.5400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2797
    Cell Significance Index: -4.1300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2910
    Cell Significance Index: -3.9700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2947
    Cell Significance Index: -23.3400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2987
    Cell Significance Index: -22.2600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2999
    Cell Significance Index: -9.5500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3018
    Cell Significance Index: -9.8800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3338
    Cell Significance Index: -6.6000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.3417
    Cell Significance Index: -6.8600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.3529
    Cell Significance Index: -4.4000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3626
    Cell Significance Index: -19.0400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.3639
    Cell Significance Index: -9.9100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4221
    Cell Significance Index: -9.1200
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.4572
    Cell Significance Index: -5.7700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5121
    Cell Significance Index: -17.9400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.5409
    Cell Significance Index: -7.7800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.5436
    Cell Significance Index: -13.5600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.5469
    Cell Significance Index: -13.3500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.5521
    Cell Significance Index: -9.2400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** FKTN is a single-copy gene located on chromosome 15q24.3. The gene consists of 13 exons and encodes a protein of 343 amino acids. The FKTN protein is a member of the ribitol-5-phosphate transferase family and is involved in the transfer of ribitol-5-phosphate to the carbohydrate moiety of glycoproteins. This process is essential for the proper functioning of glycoproteins, which play critical roles in various cellular processes, including cell signaling, adhesion, and transport. **Pathways and Functions** FKTN is involved in several key pathways, including: 1. **Protein glycosylation**: FKTN is essential for the transfer of ribitol-5-phosphate to the carbohydrate moiety of glycoproteins, which is a critical step in the formation of glycoproteins. 2. **Cis-Golgi network**: FKTN is localized to the cis-Golgi network, where it interacts with other proteins involved in glycoprotein synthesis and modification. 3. **Endoplasmic reticulum**: FKTN is also localized to the endoplasmic reticulum, where it interacts with other proteins involved in glycoprotein synthesis and transport. FKTN's role in these pathways is critical for maintaining the structural integrity and function of glycoproteins. Mutations in the FKTN gene can disrupt glycoprotein synthesis and function, leading to various neurological and muscular disorders. **Clinical Significance** Mutations in the FKTN gene have been associated with several clinical conditions, including: 1. **Fukuyama congenital muscular dystrophy (FCMD)**: A rare and severe neuromuscular disorder characterized by muscle weakness, developmental delays, and intellectual disability. 2. **Epilepsy**: FKTN mutations have been implicated in the development of epilepsy, particularly in individuals with intellectual disability. 3. **Autism**: FKTN mutations have also been associated with autism spectrum disorder, particularly in individuals with intellectual disability. 4. **Schizophrenia**: FKTN mutations have been implicated in the development of schizophrenia, particularly in individuals with a family history of the disorder. In conclusion, FKTN is a critical gene involved in the regulation of protein glycosylation, a process essential for maintaining the structural integrity and function of proteins. Mutations in the FKTN gene have been associated with various neurological and muscular disorders, highlighting the importance of this gene in human health and disease. Further research is needed to fully elucidate the role of FKTN in human disease and to develop effective therapeutic strategies for individuals affected by FKTN-related disorders.

Genular Protein ID: 2843878226

Symbol: FKTN_HUMAN

Name: Ribitol-5-phosphate transferase FKTN

UniProtKB Accession Codes:

O75072 B4DUX9 J3KP13 Q3MIJ1 Q96TE1 Q9P295

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 5 ChiTaRS 1 ComplexPortal 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 3 ExpressionAtlas 1 GO 15 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 9 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 6 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 6 Rhea 4 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9690476

Title: An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy.

PubMed ID: 9690476

DOI: 10.1038/28653

PubMed ID: 11165248

Title: Structural organization, complete genomic sequences and mutational analyses of the Fukuyama-type congenital muscular dystrophy gene, fukutin.

PubMed ID: 11165248

DOI: 10.1016/s0014-5793(01)02088-9

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10817652

Title: Haplotype-phenotype correlation in Fukuyama congenital muscular dystrophy.

PubMed ID: 10817652

DOI: 10.1002/(sici)1096-8628(20000529)92:3<184::aid-ajmg5>3.0.co;2-n

PubMed ID: 11115853

Title: Neuronal expression of the fukutin gene.

PubMed ID: 11115853

DOI: 10.1093/hmg/9.20.3083

PubMed ID: 11445638

Title: Selective deficiency of alpha-dystroglycan in Fukuyama-type congenital muscular dystrophy.

PubMed ID: 11445638

DOI: 10.1212/wnl.57.1.115

PubMed ID: 12601708

Title: A new mutation of the fukutin gene in a non-Japanese patient.

PubMed ID: 12601708

DOI: 10.1002/ana.10491

PubMed ID: 14627679

Title: A homozygous nonsense mutation in the fukutin gene causes a Walker-Warburg syndrome phenotype.

PubMed ID: 14627679

DOI: 10.1136/jmg.40.11.845

PubMed ID: 17034757

Title: Molecular interaction between fukutin and POMGnT1 in the glycosylation pathway of alpha-dystroglycan.

PubMed ID: 17034757

DOI: 10.1016/j.bbrc.2006.09.129

PubMed ID: 18177472

Title: Two new patients bearing mutations in the fukutin gene confirm the relevance of this gene in Walker-Warburg syndrome.

PubMed ID: 18177472

DOI: 10.1111/j.1399-0004.2007.00936.x

PubMed ID: 22958903

Title: Exome sequencing and functional validation in zebrafish identify GTDC2 mutations as a cause of Walker-Warburg syndrome.

PubMed ID: 22958903

DOI: 10.1016/j.ajhg.2012.07.009

PubMed ID: 25279699

Title: The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated alpha-dystroglycan functional glycosylation.

PubMed ID: 25279699

DOI: 10.7554/elife.03941

PubMed ID: 27194101

Title: ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto alpha-dystroglycan.

PubMed ID: 27194101

DOI: 10.1038/ncomms11534

PubMed ID: 26923585

Title: Identification of a Post-translational Modification with Ribitol-Phosphate and Its Defect in Muscular Dystrophy.

PubMed ID: 26923585

DOI: 10.1016/j.celrep.2016.02.017

PubMed ID: 29477842

Title: Cell endogenous activities of fukutin and FKRP coexist with the ribitol xylosyltransferase, TMEM5.

PubMed ID: 29477842

DOI: 10.1016/j.bbrc.2018.02.162

PubMed ID: 29416295

Title: Expression in retinal neurons of fukutin and FKRP, the protein products of two dystroglycanopathy-causative genes.

PubMed ID: 29416295

PubMed ID: 10545611

Title: Novel mutations and genotype-phenotype relationships in 107 families with Fukuyama-type congenital muscular dystrophy (FCMD).

PubMed ID: 10545611

DOI: 10.1093/hmg/8.12.2303

PubMed ID: 17036286

Title: Fukutin gene mutations cause dilated cardiomyopathy with minimal muscle weakness.

PubMed ID: 17036286

DOI: 10.1002/ana.20973

PubMed ID: 17044012

Title: Fukutin gene mutations in steroid-responsive limb girdle muscular dystrophy.

PubMed ID: 17044012

DOI: 10.1002/ana.21006

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 19299310

Title: Congenital muscular dystrophies with defective glycosylation of dystroglycan: a population study.

PubMed ID: 19299310

DOI: 10.1212/01.wnl.0000346518.68110.60

PubMed ID: 19179078

Title: Four Caucasian patients with mutations in the fukutin gene and variable clinical phenotype.

PubMed ID: 19179078

DOI: 10.1016/j.nmd.2008.12.005

PubMed ID: 19342235

Title: Further evidence of Fukutin mutations as a cause of childhood onset limb-girdle muscular dystrophy without mental retardation.

PubMed ID: 19342235

DOI: 10.1016/j.nmd.2009.03.001

PubMed ID: 24530477

Title: Novel mutation in the fukutin gene in an Egyptian family with Fukuyama congenital muscular dystrophy and microcephaly.

PubMed ID: 24530477

DOI: 10.1016/j.gene.2014.01.070

Sequence Information:

  • Length: 461
  • Mass: 53724
  • Checksum: 2D11F28E4BCCD858
  • Sequence:
    • MSRINKNVVL ALLTLTSSAF LLFQLYYYKH YLSTKNGAGL SKSKGSRIGF DSTQWRAVKK 
FIMLTSNQNV PVFLIDPLIL ELINKNFEQV KNTSHGSTSQ CKFFCVPRDF TAFALQYHLW 
KNEEGWFRIA ENMGFQCLKI ESKDPRLDGI DSLSGTEIPL HYICKLATHA IHLVVFHERS 
GNYLWHGHLR LKEHIDRKFV PFRKLQFGRY PGAFDRPELQ QVTVDGLEVL IPKDPMHFVE 
EVPHSRFIEC RYKEARAFFQ QYLDDNTVEA VAFRKSAKEL LQLAAKTLNK LGVPFWLSSG 
TCLGWYRQCN IIPYSKDVDL GIFIQDYKSD IILAFQDAGL PLKHKFGKVE DSLELSFQGK 
DDVKLDVFFF YEETDHMWNG GTQAKTGKKF KYLFPKFTLC WTEFVDMKVH VPCETLEYIE 
ANYGKTWKIP VKTWDWKRSP PNVQPNGIWP ISEWDEVIQL Y

Genular Protein ID: 3864068067

Symbol: B4E2W4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E2W4

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 ProteomicsDB 1 RefSeq 2

Sequence Information:

  • Length: 271
  • Mass: 31533
  • Checksum: 121C9E197A7139C1
  • Sequence:
    • MSRINKNVVL ALLTLTSSAF LLFQLYYYKH YLSTKNGAGL SKSKGSRIGF DSTQWRAVKK 
FIMLTSNQNV PVFLIDPLIL ELINKNFEQV KNTSHGSTSQ CKFFCVPRDF TAFALQYHLW 
KNEEGWFRIA ENMGFQCLKI ESKDPRLDGI DSLSGTEIPL HYICKLATHA IHLVVFHERS 
GNYLWHGHLR LKEHIDRKFV PFRKLQFGRY PGAFDRPELQ QVTVDGLEVL IPKDPMHFVE 
EVPHSRFIEC RYKEARAFFQ IPVSEVYTVL D

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.