Details for: FUT6
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 26.0696
Cell Significance Index: -4.0600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 15.6519
Cell Significance Index: -3.9700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 2.5876
Cell Significance Index: 74.5600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.4925
Cell Significance Index: 172.3700 - Cell Name: precursor cell (CL0011115)
Fold Change: 2.4318
Cell Significance Index: 18.4400 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 2.2440
Cell Significance Index: 24.3200 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 2.0445
Cell Significance Index: 21.0900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 2.0279
Cell Significance Index: 91.9200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 1.6761
Cell Significance Index: -4.4900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.4706
Cell Significance Index: 31.8600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.4497
Cell Significance Index: 1309.0100 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.3569
Cell Significance Index: 81.4600 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.3368
Cell Significance Index: 20.0300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.1721
Cell Significance Index: 127.4900 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 1.0940
Cell Significance Index: 26.5000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9099
Cell Significance Index: 147.9900 - Cell Name: mucus secreting cell of tracheobronchial tree submucosal gland (CL4033037)
Fold Change: 0.8386
Cell Significance Index: 5.6000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.7204
Cell Significance Index: 25.3200 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 0.6612
Cell Significance Index: 6.6700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.5888
Cell Significance Index: 12.5400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.5722
Cell Significance Index: 26.6800 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.5091
Cell Significance Index: 10.5600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4494
Cell Significance Index: 44.4600 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.4095
Cell Significance Index: 3.5800 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.2257
Cell Significance Index: 3.0800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.2173
Cell Significance Index: 6.9600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2172
Cell Significance Index: 5.4300 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.2093
Cell Significance Index: 3.5200 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.2015
Cell Significance Index: 1.5400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.1609
Cell Significance Index: 10.1400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1183
Cell Significance Index: 22.5200 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: 0.0945
Cell Significance Index: 1.9700 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.0864
Cell Significance Index: 1.0300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0760
Cell Significance Index: 2.1200 - Cell Name: duodenum glandular cell (CL1001589)
Fold Change: 0.0558
Cell Significance Index: 0.4000 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.0440
Cell Significance Index: 0.6500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0436
Cell Significance Index: 2.2700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0394
Cell Significance Index: 1.8500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0305
Cell Significance Index: 6.0600 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.0249
Cell Significance Index: 0.4200 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: 0.0242
Cell Significance Index: 0.2000 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.0111
Cell Significance Index: 0.3500 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0105
Cell Significance Index: 1.3500 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0094
Cell Significance Index: 1.2200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0093
Cell Significance Index: 1.0700 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.0082
Cell Significance Index: 0.0700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0052
Cell Significance Index: 1.0400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0040
Cell Significance Index: 1.4400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0018
Cell Significance Index: 0.3300 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0002
Cell Significance Index: -0.1000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0010
Cell Significance Index: -1.8000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0018
Cell Significance Index: -3.3200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0019
Cell Significance Index: -2.8900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0025
Cell Significance Index: -3.4000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0043
Cell Significance Index: -3.2200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0047
Cell Significance Index: -0.0800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0050
Cell Significance Index: -3.6800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0052
Cell Significance Index: -3.8900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0061
Cell Significance Index: -3.9000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0070
Cell Significance Index: -0.8100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0070
Cell Significance Index: -3.9500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0083
Cell Significance Index: -0.2300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0084
Cell Significance Index: -3.8000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0106
Cell Significance Index: -3.0500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0154
Cell Significance Index: -1.5700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0159
Cell Significance Index: -1.9500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0169
Cell Significance Index: -2.8900 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.0169
Cell Significance Index: -0.1100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0185
Cell Significance Index: -0.4800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0192
Cell Significance Index: -4.0500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0232
Cell Significance Index: -3.3700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0238
Cell Significance Index: -3.2700 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: -0.0242
Cell Significance Index: -0.1700 - Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
Fold Change: -0.0290
Cell Significance Index: -0.2900 - Cell Name: enterocyte (CL0000584)
Fold Change: -0.0379
Cell Significance Index: -0.2400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0389
Cell Significance Index: -4.0600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0390
Cell Significance Index: -4.6000 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0431
Cell Significance Index: -2.1800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0434
Cell Significance Index: -3.4400 - Cell Name: stem cell (CL0000034)
Fold Change: -0.0482
Cell Significance Index: -0.3500 - Cell Name: glandular cell of esophagus (CL0002657)
Fold Change: -0.0514
Cell Significance Index: -0.5500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0533
Cell Significance Index: -4.0900 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0543
Cell Significance Index: -2.2300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0547
Cell Significance Index: -3.6800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0553
Cell Significance Index: -3.3900 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0572
Cell Significance Index: -2.1000 - Cell Name: salivary gland cell (CL0009005)
Fold Change: -0.0596
Cell Significance Index: -0.7400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0605
Cell Significance Index: -4.5100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0656
Cell Significance Index: -3.6800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0657
Cell Significance Index: -4.2400 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0657
Cell Significance Index: -0.9900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0678
Cell Significance Index: -4.1700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0680
Cell Significance Index: -3.5700 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: -0.0750
Cell Significance Index: -1.0400 - Cell Name: serous secreting cell (CL0000313)
Fold Change: -0.0773
Cell Significance Index: -0.6800 - Cell Name: goblet cell (CL0000160)
Fold Change: -0.0774
Cell Significance Index: -0.7000 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0777
Cell Significance Index: -1.9400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0860
Cell Significance Index: -2.9900 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: -0.0876
Cell Significance Index: -0.3300 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: -0.0900
Cell Significance Index: -1.1400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 148463859
Symbol: FUT6_HUMAN
Name: Fucosyltransferase 6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1520296
Title: The cloning and expression of a human alpha-1,3 fucosyltransferase capable of forming the E-selectin ligand.
PubMed ID: 1520296
PubMed ID: 1339443
Title: Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes.
PubMed ID: 1339443
PubMed ID: 7650030
Title: Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms.
PubMed ID: 7650030
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 9451035
Title: Trafficking and localization studies of recombinant alpha1, 3-fucosyltransferase VI stably expressed in CHO cells.
PubMed ID: 9451035
PubMed ID: 9363434
Title: Acceptor specificity of GDP-Fuc:Gal beta 1-->4GlcNAc-R alpha 3-fucosyltransferase VI (FucT VI) expressed in insect cells as soluble, secreted enzyme.
PubMed ID: 9363434
PubMed ID: 10728707
Title: Expression of sialyl 6-sulfo Lewis X is inversely correlated with conventional sialyl Lewis X expression in human colorectal cancer.
PubMed ID: 10728707
PubMed ID: 17604274
Title: Site-specific fucosylation of sialylated polylactosamines by alpha1,3/4-fucosyltransferases-V and -VI Is defined by amino acids near the N terminus of the catalytic domain.
PubMed ID: 17604274
PubMed ID: 29593094
Title: Distinct human alpha(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.
PubMed ID: 29593094
PubMed ID: 8175676
Title: Molecular basis for plasma alpha(1,3)-fucosyltransferase gene deficiency (FUT6).
PubMed ID: 8175676
PubMed ID: 11102976
Title: Identification of two functionally deficient plasma alpha 3-fucosyltransferase (FUT6) alleles.
PubMed ID: 11102976
DOI: 10.1002/1098-1004(200012)16:6<473::aid-humu4>3.0.co;2-t
PubMed ID: 27535533
Title: Analysis of protein-coding genetic variation in 60,706 humans.
PubMed ID: 27535533
DOI: 10.1038/nature19057
Sequence Information:
- Length: 359
- Mass: 41860
- Checksum: 67ABDF058F0999DA
- Sequence:
MDPLGPAKPQ WSWRCCLTTL LFQLLMAVCF FSYLRVSQDD PTVYPNGSRF PDSTGTPAHS IPLILLWTWP FNKPIALPRC SEMVPGTADC NITADRKVYP QADAVIVHHR EVMYNPSAQL PRSPRRQGQR WIWFSMESPS HCWQLKAMDG YFNLTMSYRS DSDIFTPYGW LEPWSGQPAH PPLNLSAKTE LVAWAVSNWG PNSARVRYYQ SLQAHLKVDV YGRSHKPLPQ GTMMETLSRY KFYLAFENSL HPDYITEKLW RNALEAWAVP VVLGPSRSNY ERFLPPDAFI HVDDFQSPKD LARYLQELDK DHARYLSYFR WRETLRPRSF SWALAFCKAC WKLQEESRYQ TRGIAAWFT
Genular Protein ID: 1038591100
Symbol: Q6P7E6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 359
- Mass: 41858
- Checksum: C77818F802A00674
- Sequence:
MDPLGPAKPQ WSWRCCLTTL LFHLLMAVCF FSYLRVSQDD PTVYPNGSRF PDSTGTPAHS IPLILLWTWP FNKPIALPRC SEMVPGTADC NITADRKVYP QADAVIVHHR EVMYNPSAQL PRSSRRQGQR WIWFSMESPS HCWQLKAMDG YFNLTMSYRS DSDIFTPYGW LEPWSGQPAH PPLNLSAKTE LVAWAVSNWG PNSARVRYYQ SLQAHLKVDV YGRSHKPLPQ GTMMETLSRY KFYLAFKNSL HPDYITEKLW RNALEAWAVP VVLGPSRSNY ERFLPPDAFI HVDDFQSPKD LARYLQELDK DHARYLSYFR WRETLRPRSF SWALAFCKAC WKLQEESRYQ TRGIAAWFT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.