Details for: VPS41

Gene ID: 27072

Symbol: VPS41

Ensembl ID: ENSG00000006715

Description: VPS41 subunit of HOPS complex

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 303.3201
    Cell Significance Index: -47.1800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 181.2387
    Cell Significance Index: -45.9700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 104.2102
    Cell Significance Index: -49.2000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 96.3183
    Cell Significance Index: -39.1300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 87.4247
    Cell Significance Index: -44.9700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 41.1105
    Cell Significance Index: -39.2500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 39.2958
    Cell Significance Index: -48.4500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 16.9662
    Cell Significance Index: -45.4500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 15.8980
    Cell Significance Index: -48.8300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 12.5469
    Cell Significance Index: -27.4600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.3807
    Cell Significance Index: -48.8600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.3693
    Cell Significance Index: 475.2700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.0864
    Cell Significance Index: 339.3400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.4790
    Cell Significance Index: 83.0000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.2869
    Cell Significance Index: 461.6000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.2464
    Cell Significance Index: 247.3500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.2248
    Cell Significance Index: 46.3800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.1992
    Cell Significance Index: 53.0500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.1284
    Cell Significance Index: 69.3600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.0913
    Cell Significance Index: 118.7000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9869
    Cell Significance Index: 59.2500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.8527
    Cell Significance Index: 20.4500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.6960
    Cell Significance Index: 481.3800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.6821
    Cell Significance Index: 122.9700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5379
    Cell Significance Index: 66.1400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.5153
    Cell Significance Index: 13.7600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4629
    Cell Significance Index: 35.5300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4294
    Cell Significance Index: 28.8800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.4128
    Cell Significance Index: 11.7800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3296
    Cell Significance Index: 180.0100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3093
    Cell Significance Index: 6.7000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2866
    Cell Significance Index: 258.7500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2567
    Cell Significance Index: 483.3600
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.2333
    Cell Significance Index: 3.5500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2167
    Cell Significance Index: 29.7700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1971
    Cell Significance Index: 5.6800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1605
    Cell Significance Index: 296.0400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1391
    Cell Significance Index: 214.1800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1248
    Cell Significance Index: 8.6300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1104
    Cell Significance Index: 21.0100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1008
    Cell Significance Index: 44.5800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0946
    Cell Significance Index: 60.1100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0809
    Cell Significance Index: 36.7100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0547
    Cell Significance Index: 2.4800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0546
    Cell Significance Index: 74.2600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.0523
    Cell Significance Index: 1.0200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0369
    Cell Significance Index: 1.9200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0362
    Cell Significance Index: 1.8800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0162
    Cell Significance Index: 0.4400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0035
    Cell Significance Index: 0.6000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0004
    Cell Significance Index: 0.0400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0166
    Cell Significance Index: -12.2900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0174
    Cell Significance Index: -10.8600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0189
    Cell Significance Index: -13.8300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0302
    Cell Significance Index: -1.4100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0439
    Cell Significance Index: -33.2500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0538
    Cell Significance Index: -6.3500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0671
    Cell Significance Index: -37.8500
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0882
    Cell Significance Index: -1.4200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0901
    Cell Significance Index: -3.1700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0979
    Cell Significance Index: -10.0000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1005
    Cell Significance Index: -2.8100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1088
    Cell Significance Index: -2.3300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1296
    Cell Significance Index: -27.3000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1327
    Cell Significance Index: -17.0100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1431
    Cell Significance Index: -41.1700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1474
    Cell Significance Index: -21.4200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2228
    Cell Significance Index: -28.7800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2323
    Cell Significance Index: -14.9900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2324
    Cell Significance Index: -4.9500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2357
    Cell Significance Index: -4.0400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2379
    Cell Significance Index: -27.7200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2403
    Cell Significance Index: -15.1500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2572
    Cell Significance Index: -29.4700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2591
    Cell Significance Index: -29.5800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3038
    Cell Significance Index: -14.2800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3409
    Cell Significance Index: -35.5000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.3692
    Cell Significance Index: -8.0900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3765
    Cell Significance Index: -28.0600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.3882
    Cell Significance Index: -3.5800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4053
    Cell Significance Index: -21.2800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4574
    Cell Significance Index: -6.2400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4763
    Cell Significance Index: -37.7200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4876
    Cell Significance Index: -12.8200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.5063
    Cell Significance Index: -35.8100
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.5092
    Cell Significance Index: -6.3500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5409
    Cell Significance Index: -17.7100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5777
    Cell Significance Index: -18.4000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5973
    Cell Significance Index: -12.3900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6560
    Cell Significance Index: -21.0100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.6626
    Cell Significance Index: -11.0900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.6686
    Cell Significance Index: -14.1900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.6833
    Cell Significance Index: -17.0800
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.6901
    Cell Significance Index: -8.7100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7001
    Cell Significance Index: -42.9200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.7237
    Cell Significance Index: -16.7200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.7324
    Cell Significance Index: -25.4500
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.7363
    Cell Significance Index: -7.6700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.7495
    Cell Significance Index: -10.7800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.7743
    Cell Significance Index: -15.3100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Expression and localization**: VPS41 is expressed in a wide range of cell types, including corneal endothelial cells, astrocytes, and neurons. Its localization is primarily associated with late endosomes and lysosomes. 2. **Function**: VPS41 plays a critical role in the regulation of snare complex assembly, which is essential for vesicle-mediated transport. This function is crucial for the proper trafficking of proteins and lipids within cells. 3. **Interactions**: VPS41 interacts with other proteins, including VPS35, VPS18, and VPS29, to form the HOPS complex. These interactions are essential for the regulation of endosomal trafficking and protein transport. 4. **Disease association**: VPS41 has been implicated in various diseases, including infectious diseases, such as SARS-CoV-2 infection. Its dysregulation can lead to impaired endosomal trafficking, resulting in disease progression. **Pathways and Functions** 1. **Endosomal trafficking**: VPS41 is involved in the regulation of late endosome and lysosome fusion, ensuring the proper degradation and recycling of cellular components. 2. **Vesicle-mediated transport**: VPS41 plays a crucial role in the regulation of snare complex assembly, which is essential for vesicle-mediated transport. This function is critical for the trafficking of proteins and lipids within cells. 3. **Protein targeting to vacuole**: VPS41 is involved in the targeting of proteins to vacuoles, a process essential for cellular homeostasis. 4. **Autophagy**: VPS41 has been implicated in the regulation of autophagy, a process essential for cellular homeostasis and disease progression. **Clinical Significance** 1. **Infectious diseases**: VPS41 has been implicated in SARS-CoV-2 infection, where its dysregulation can lead to impaired endosomal trafficking, resulting in disease progression. 2. **Autoimmune diseases**: VPS41 has been implicated in autoimmune diseases, such as multiple sclerosis, where its dysregulation can lead to impaired endosomal trafficking and disease progression. 3. **Cancer**: VPS41 has been implicated in cancer, where its dysregulation can lead to impaired endosomal trafficking and disease progression. 4. **Neurological disorders**: VPS41 has been implicated in neurological disorders, such as Alzheimer's disease, where its dysregulation can lead to impaired endosomal trafficking and disease progression. In conclusion, VPS41 is a critical component of the HOPS complex, playing a pivotal role in endosomal trafficking and protein transport within cells. Its dysregulation has been implicated in various diseases, including infectious diseases, autoimmune diseases, cancer, and neurological disorders. Further research is necessary to fully understand the complexities of VPS41 and its role in disease progression.

Genular Protein ID: 1916127755

Symbol: VPS41_HUMAN

Name: Vacuolar protein sorting-associated protein 41 homolog

UniProtKB Accession Codes:

P49754 E9PF36 Q86TP8 Q99851 Q99852

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 2 ExpressionAtlas 1 GO 26 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9159129

Title: Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast.

PubMed ID: 9159129

DOI: 10.1073/pnas.94.11.5662

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7596406

Title: Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.

PubMed ID: 7596406

DOI: 10.1038/375754a0

PubMed ID: 20434987

Title: Identification of the switch in early-to-late endosome transition.

PubMed ID: 20434987

DOI: 10.1016/j.cell.2010.03.011

PubMed ID: 19850127

Title: VPS41, a protein involved in lysosomal trafficking, is protective in Caenorhabditis elegans and mammalian cellular models of Parkinson's disease.

PubMed ID: 19850127

DOI: 10.1016/j.nbd.2009.10.011

PubMed ID: 21802320

Title: Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b.

PubMed ID: 21802320

DOI: 10.1016/j.immuni.2011.06.009

PubMed ID: 21411634

Title: Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells.

PubMed ID: 21411634

DOI: 10.1091/mbc.e10-10-0799

PubMed ID: 22323726

Title: Functional analysis of VPS41-mediated neuroprotection in Caenorhabditis elegans and mammalian models of Parkinson's disease.

PubMed ID: 22323726

DOI: 10.1523/jneurosci.2606-11.2012

PubMed ID: 24210660

Title: Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway.

PubMed ID: 24210660

DOI: 10.1016/j.devcel.2013.10.007

PubMed ID: 23351085

Title: Tethering complexes in the endocytic pathway: CORVET and HOPS.

PubMed ID: 23351085

DOI: 10.1111/febs.12151

PubMed ID: 23322049

Title: hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins.

PubMed ID: 23322049

DOI: 10.1038/ncomms2360

PubMed ID: 23167963

Title: The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion.

PubMed ID: 23167963

DOI: 10.1111/tra.12027

PubMed ID: 25445562

Title: RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking.

PubMed ID: 25445562

DOI: 10.1038/srep07282

PubMed ID: 25908847

Title: The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes.

PubMed ID: 25908847

DOI: 10.1242/jcs.162651

PubMed ID: 25783203

Title: Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes.

PubMed ID: 25783203

DOI: 10.1111/tra.12283

PubMed ID: 28325809

Title: The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes.

PubMed ID: 28325809

DOI: 10.1083/jcb.201607085

PubMed ID: 31806350

Title: The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1.

PubMed ID: 31806350

DOI: 10.1016/j.molcel.2019.10.035

PubMed ID: 32808683

Title: Loss-of-Function Variants in HOPS Complex Genes VPS16 and VPS41 Cause Early Onset Dystonia Associated with Lysosomal Abnormalities.

PubMed ID: 32808683

DOI: 10.1002/ana.25879

PubMed ID: 33422265

Title: ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation.

PubMed ID: 33422265

DOI: 10.1016/j.devcel.2020.12.010

PubMed ID: 33764426

Title: Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking.

PubMed ID: 33764426

DOI: 10.1093/brain/awaa459

PubMed ID: 33851776

Title: Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1-dependent TFEB/TFE3 regulation.

PubMed ID: 33851776

DOI: 10.15252/emmm.202013258

Sequence Information:

  • Length: 854
  • Mass: 98566
  • Checksum: 037577D5FA3A18A0
  • Sequence:
    • MAEAEEQETG SLEESTDESE EEESEEEPKL KYERLSNGVT EILQKDAASC MTVHDKFLAL 
GTHYGKVYLL DVQGNITQKF DVSPVKINQI SLDESGEHMG VCSEDGKVQV FGLYSGEEFH 
ETFDCPIKII AVHPHFVRSS CKQFVTGGKK LLLFERSWMN RWKSAVLHEG EGNIRSVKWR 
GHLIAWANNM GVKIFDIISK QRITNVPRDD ISLRPDMYPC SLCWKDNVTL IIGWGTSVKV 
CSVKERHASE MRDLPSRYVE IVSQFETEFY ISGLAPLCDQ LVVLSYVKEI SEKTEREYCA 
RPRLDIIQPL SETCEEISSD ALTVRGFQEN ECRDYHLEYS EGESLFYIVS PRDVVVAKER 
DQDDHIDWLL EKKKYEEALM AAEISQKNIK RHKILDIGLA YINHLVERGD YDIAARKCQK 
ILGKNAALWE YEVYKFKEIG QLKAISPYLP RGDPVLKPLI YEMILHEFLE SDYEGFATLI 
REWPGDLYNN SVIVQAVRDH LKKDSQNKTL LKTLAELYTY DKNYGNALEI YLTLRHKDVF 
QLIHKHNLFS SIKDKIVLLM DFDSEKAVDM LLDNEDKISI KKVVEELEDR PELQHVYLHK 
LFKRDHHKGQ RYHEKQISLY AEYDRPNLLP FLRDSTHCPL EKALEICQQR NFVEETVYLL 
SRMGNSRSAL KMIMEELHDV DKAIEFAKEQ DDGELWEDLI LYSIDKPPFI TGLLNNIGTH 
VDPILLIHRI KEGMEIPNLR DSLVKILQDY NLQILLREGC KKILVADSLS LLKKMHRTQM 
KGVLVDEENI CESCLSPILP SDAAKPFSVV VFHCRHMFHK ECLPMPSMNS AAQFCNICSA 
KNRGPGSAIL EMKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.