Details for: DENND2A
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 219.2288
Cell Significance Index: -34.1000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 136.4120
Cell Significance Index: -34.6000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 72.1846
Cell Significance Index: -34.0800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 27.6652
Cell Significance Index: -34.1100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 13.0914
Cell Significance Index: -35.0700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 11.2904
Cell Significance Index: -24.7100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 8.7708
Cell Significance Index: -34.6100 - Cell Name: preadipocyte (CL0002334)
Fold Change: 3.1705
Cell Significance Index: 61.8800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 3.0783
Cell Significance Index: 172.7400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 2.2932
Cell Significance Index: 333.3400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.1194
Cell Significance Index: 760.1900 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 1.8567
Cell Significance Index: 12.5800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.8486
Cell Significance Index: 83.7900 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.3765
Cell Significance Index: 20.6300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9249
Cell Significance Index: 835.0800 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.9157
Cell Significance Index: 13.1500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.8885
Cell Significance Index: 176.3300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.8426
Cell Significance Index: 51.7900 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.7255
Cell Significance Index: 17.4000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6645
Cell Significance Index: 108.0800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.6614
Cell Significance Index: 71.9500 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.6390
Cell Significance Index: 8.9700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5597
Cell Significance Index: 55.3700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.5562
Cell Significance Index: 111.5700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.4596
Cell Significance Index: 23.2200 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.4259
Cell Significance Index: 6.1300 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 0.3938
Cell Significance Index: 6.4900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.3678
Cell Significance Index: 254.3900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.3154
Cell Significance Index: 593.8400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2460
Cell Significance Index: 17.0200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.2389
Cell Significance Index: 5.2300 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2096
Cell Significance Index: 5.2400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1387
Cell Significance Index: 26.4000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1109
Cell Significance Index: 15.2400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1093
Cell Significance Index: 3.1500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0740
Cell Significance Index: 2.6000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0512
Cell Significance Index: 3.2300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0035
Cell Significance Index: 0.0600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0054
Cell Significance Index: -10.0500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0074
Cell Significance Index: -11.3400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0151
Cell Significance Index: -20.4800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0226
Cell Significance Index: -14.3700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0236
Cell Significance Index: -17.2700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0245
Cell Significance Index: -0.5300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0272
Cell Significance Index: -4.9100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0280
Cell Significance Index: -12.7300 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0296
Cell Significance Index: -16.1800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0359
Cell Significance Index: -26.5600 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.0472
Cell Significance Index: -0.6600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0500
Cell Significance Index: -37.8800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0527
Cell Significance Index: -29.7200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0582
Cell Significance Index: -25.7400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0620
Cell Significance Index: -38.7400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0955
Cell Significance Index: -27.4700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1673
Cell Significance Index: -35.2400 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1779
Cell Significance Index: -22.8100 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1822
Cell Significance Index: -3.7800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1869
Cell Significance Index: -3.9800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1880
Cell Significance Index: -32.1100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.2032
Cell Significance Index: -24.9900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2113
Cell Significance Index: -14.2100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2563
Cell Significance Index: -33.1100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2660
Cell Significance Index: -8.5200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2733
Cell Significance Index: -31.8500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.2957
Cell Significance Index: -22.7000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3035
Cell Significance Index: -31.6000 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.3038
Cell Significance Index: -7.3600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.3144
Cell Significance Index: -37.0800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3151
Cell Significance Index: -36.1000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.3310
Cell Significance Index: -33.8100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3872
Cell Significance Index: -30.6700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3945
Cell Significance Index: -24.1900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.4011
Cell Significance Index: -10.7100 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.4431
Cell Significance Index: -11.0500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.4514
Cell Significance Index: -33.6400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.4598
Cell Significance Index: -7.7000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4975
Cell Significance Index: -26.1200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.5258
Cell Significance Index: -7.5300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.5290
Cell Significance Index: -17.3200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.5412
Cell Significance Index: -23.9400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.5599
Cell Significance Index: -11.2400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.5636
Cell Significance Index: -36.3600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.5674
Cell Significance Index: -14.9200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.5700
Cell Significance Index: -29.6900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.5919
Cell Significance Index: -30.7500 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: -0.6267
Cell Significance Index: -5.6500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.6355
Cell Significance Index: -24.0700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.6487
Cell Significance Index: -30.4900 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.6544
Cell Significance Index: -13.8900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.6591
Cell Significance Index: -17.6600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.6629
Cell Significance Index: -18.5300 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.6802
Cell Significance Index: -11.7600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.6868
Cell Significance Index: -32.0200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.7313
Cell Significance Index: -20.8700 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.7521
Cell Significance Index: -16.2500 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -0.7549
Cell Significance Index: -9.7900 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.7844
Cell Significance Index: -15.5100 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.7896
Cell Significance Index: -27.6600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.7974
Cell Significance Index: -25.4000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.8026
Cell Significance Index: -27.8900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 11276618
Symbol: DEN2A_HUMAN
Name: DENN domain-containing protein 2A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10574462
Title: Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10574462
PubMed ID: 12853948
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 20937701
Title: Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.
PubMed ID: 20937701
Sequence Information:
- Length: 1009
- Mass: 113853
- Checksum: 4A596E6999F8AF3E
- Sequence:
MDMFSLDMII SDPAAEASRA GKKQLRGVQN PCPSARARPR HKSLNIKDKI SEWEGKKEVP TPAPSRRADG QEDYLPSSTV ERRSSDGVRT QVTEAKNGMR PGTESTEKER NKGAVNVGGQ DPEPGQDLSQ PEREVDPSWG RGREPRLGKL RFQNDPLSVL KQVKKLEQAL KDGSAGLDPQ LPGTCYSPHC PPDKAEAGST LPENLGGGSG SEVSQRVHPS DLEGREPTPE LVEDRKGSCR RPWDRSLENV YRGSEGSPTK PFINPLPKPR RTFKHAGEGD KDGKPGIGFR KEKRNLPPLP SLPPPPLPSS PPPSSVNRRL WTGRQKSSAD HRKSYEFEDL LQSSSESSRV DWYAQTKLGL TRTLSEENVY EDILDPPMKE NPYEDIELHG RCLGKKCVLN FPASPTSSIP DTLTKQSLSK PAFFRQNSER RNFKLLDTRK LSRDGTGSPS KISPPSTPSS PDDIFFNLGD PQNGRKKRKI PKLVLRINAI YEVRRGKKRV KRLSQSMESN SGKVTDENSE SDSDTEEKLK AHSQRLVNVK SRLKQAPRYP SLARELIEYQ ERQLFEYFVV VSLHKKQAGA AYVPELTQQF PLKLERSFKF MREAEDQLKA IPQFCFPDAK DWVPVQQFTS ETFSFVLTGE DGSRRFGYCR RLLPGGKGKR LPEVYCIVSR LGCFSLFSRI LDEVEKRRGI SPALVQPLMR SVMEAPFPAL GKTILVKNFL PGSGTEVIEL CRPLDSRLEH VDFESLFSSL SVRHLVCVFA SLLLERRVIF IADKLSILSK CCHAMVALIY PFAWQHTYIP VLPPAMVDIV CSPTPFLIGL LSSSLPLLRE LPLEEVLVVD LVNSRFLRQM DDEDSILPRK LQVALEHILE QRNELACEQD EGPLDGRHGP ESSPLNEVVS EAFVRFFVEI VGHYSLFLTS GEREERTLQR EAFRKAVSSK SLRHFLEVFM ETQMFRGFIQ ERELRRQDAK GLFEVRAQEY LETLPSGEHS GVNKFLKGLG NKMKFLHKK
Genular Protein ID: 1745095225
Symbol: A2RUF6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 1009
- Mass: 113893
- Checksum: D842AF405D65CFA2
- Sequence:
MDMFSLDMII SDPAAEASRA GKKQLRGVQN PCPSARARPR HKSLNIKDKI SEWEGKKEVP TPAPSRRADG QEDYLPSSTV ERRSSDGVRT QVTEAKNGMR PGTESTEKER NKGAVNVGGQ DPEPGQDLSQ PEREVDPSWG RGREPRLGKL RFQNDHLSVL KQVKKLEQAL KDGSAGLDPQ LPGTCYSPHC PPDKAEAGST LPENLGGGSG SEVSQRVHPS DLEGREPTPE LVEDRKGSCR RPWDRSLENV YRGSEGSPTK PFINPLPKPR RTFKHAGEGD KDGKPGIGFR KEKRNLPPLP SLPPPPLPSS PPPSSVNRRL WTGRQKSSAD HRKSYEFEDL LQSSSESSRV DWYAQTKLGL TRTLSEENVY EDILDPPMKE NPYEDIELHG RCLGKKCVLN FPASPTSSIP DTLTKQSLSK PAFFRQNSER RNFKLLDTRK LSRDGTGSPS KISPPSTPSS PDDIFFNLGD PQNGRKKRKI PKLVLRINAI YEVRRGKKRV KRLSQSMESN SGKVTDENSE SDSDTEEKLK AHSQRLVNVK SRLKQAPRYP SLARELIEYQ ERQLFEYFVV VSLHKKQAGA AYVPELTQQF PLKLERSFKF MREAEDQLKA IPQFCFPDAK DWVPVQQFTS ETFSFVLTGE DGSRRFGYCR RLLPGGKGKR LPEVYCIVSR LGCFSLFSRI LDEVEKRRGI SPALVQPLMR SVMEAPFPAL GKTILVKNFL PGSGTEVIEL CRPLDSRLEH VDFESLFSSL SVRHLVCVFA SLLLERRVIF IADKLSILSK CCHAMVALIY PFAWQHTYIP VLPPAMVDIV CSPTPFLIGL LSSSLPLLRE LPLEEVLVVD LVNSRFLRQM DDEDSILPRK LQVALEHILE QRNELACEQD EGPLDGRHGP ESSPLNEVVS EAFVRFFVEI VGHYSLFLTS GEREERTLQR EAFRKAVSSK SLRHFLEVFM ETQMFRGFIQ ERELRRQDAK GLFEVRAQEY LETLPSGEHS GVNKFLKGLG NKMKFLHKK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.