Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: epithelial cell of exocrine pancreas (CL1001433)
Fold Change: 391.5880
Cell Significance Index: 196.6600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 2.6179
Cell Significance Index: 447.0200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.6873
Cell Significance Index: 321.1100 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.3374
Cell Significance Index: 13.8400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.2799
Cell Significance Index: 126.6200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.0782
Cell Significance Index: 23.3600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.0166
Cell Significance Index: 61.0300 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.9947
Cell Significance Index: 24.1000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7630
Cell Significance Index: 688.9400 - Cell Name: duodenum glandular cell (CL1001589)
Fold Change: 0.6994
Cell Significance Index: 5.0100 - Cell Name: mucus secreting cell of tracheobronchial tree submucosal gland (CL4033037)
Fold Change: 0.4523
Cell Significance Index: 3.0200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.4128
Cell Significance Index: 48.1100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4024
Cell Significance Index: 27.8300 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 0.2267
Cell Significance Index: 1.0800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2072
Cell Significance Index: 5.9700 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.1553
Cell Significance Index: 1.6100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.1240
Cell Significance Index: 90.9400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1052
Cell Significance Index: 2.6300 - Cell Name: endocrine cell (CL0000163)
Fold Change: 0.0927
Cell Significance Index: 1.1200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0501
Cell Significance Index: 5.7500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0413
Cell Significance Index: 0.8800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0205
Cell Significance Index: 0.9300 - Cell Name: PP cell (CL0000696)
Fold Change: 0.0197
Cell Significance Index: 0.2000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0159
Cell Significance Index: 0.5100 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.0145
Cell Significance Index: 0.3600 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: 0.0101
Cell Significance Index: 0.1100 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0056
Cell Significance Index: 0.0800 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.0048
Cell Significance Index: 0.0600 - Cell Name: acinar cell (CL0000622)
Fold Change: 0.0032
Cell Significance Index: 0.0400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.0026
Cell Significance Index: 1.4700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.0005
Cell Significance Index: 0.0300 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.0000
Cell Significance Index: 0.0000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0016
Cell Significance Index: -3.0100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0017
Cell Significance Index: -3.1300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0020
Cell Significance Index: -1.4600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0023
Cell Significance Index: -3.0600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0024
Cell Significance Index: -3.6300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0052
Cell Significance Index: -1.4900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0054
Cell Significance Index: -3.3700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0055
Cell Significance Index: -3.5000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0055
Cell Significance Index: -1.9900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0085
Cell Significance Index: -3.8600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0095
Cell Significance Index: -0.2600 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0098
Cell Significance Index: -0.4000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0102
Cell Significance Index: -2.0300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0107
Cell Significance Index: -0.2700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0118
Cell Significance Index: -0.8800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0120
Cell Significance Index: -0.9500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0124
Cell Significance Index: -2.6200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0144
Cell Significance Index: -2.8800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0145
Cell Significance Index: -0.5100 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0153
Cell Significance Index: -0.2300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0157
Cell Significance Index: -2.8300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0188
Cell Significance Index: -0.9500 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: -0.0200
Cell Significance Index: -0.1800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0228
Cell Significance Index: -3.3200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0255
Cell Significance Index: -3.1300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0279
Cell Significance Index: -3.8300 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.0338
Cell Significance Index: -0.5700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0346
Cell Significance Index: -3.5300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0346
Cell Significance Index: -4.4700 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.0354
Cell Significance Index: -0.2400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.0401
Cell Significance Index: -0.4600 - Cell Name: stem cell (CL0000034)
Fold Change: -0.0406
Cell Significance Index: -0.3000 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: -0.0450
Cell Significance Index: -0.7700 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: -0.0493
Cell Significance Index: -0.4300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0495
Cell Significance Index: -3.1200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0498
Cell Significance Index: -3.3500 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: -0.0573
Cell Significance Index: -0.7400 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0583
Cell Significance Index: -1.2200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0679
Cell Significance Index: -3.8100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0688
Cell Significance Index: -4.2300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0714
Cell Significance Index: -3.7500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0738
Cell Significance Index: -2.7100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0813
Cell Significance Index: -3.8200 - Cell Name: retinal astrocyte (CL4033015)
Fold Change: -0.0817
Cell Significance Index: -0.8000 - Cell Name: epithelial cell (CL0000066)
Fold Change: -0.0834
Cell Significance Index: -0.8800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0842
Cell Significance Index: -2.9500 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: -0.0882
Cell Significance Index: -0.3800 - Cell Name: pulmonary capillary endothelial cell (CL4028001)
Fold Change: -0.0898
Cell Significance Index: -1.2300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0907
Cell Significance Index: -4.2300 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: -0.0925
Cell Significance Index: -0.7300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0934
Cell Significance Index: -4.8500 - Cell Name: cholangiocyte (CL1000488)
Fold Change: -0.0973
Cell Significance Index: -0.9600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1029
Cell Significance Index: -3.3700 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.1035
Cell Significance Index: -1.7100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1038
Cell Significance Index: -4.5900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1058
Cell Significance Index: -3.3700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1106
Cell Significance Index: -3.0100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.1115
Cell Significance Index: -1.9100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1131
Cell Significance Index: -3.0300 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.1158
Cell Significance Index: -2.9500 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1171
Cell Significance Index: -3.4500 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.1178
Cell Significance Index: -5.1200 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.1195
Cell Significance Index: -3.7800 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1209
Cell Significance Index: -3.4500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1223
Cell Significance Index: -3.2700 - Cell Name: glandular cell of esophagus (CL0002657)
Fold Change: -0.1223
Cell Significance Index: -1.3100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1233
Cell Significance Index: -4.6700 - Cell Name: osteoblast (CL0000062)
Fold Change: -0.1258
Cell Significance Index: -1.2200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2691943909
Symbol: GP2_HUMAN
Name: ZAP75
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8666297
Title: Sequence of the cDNA encoding human GP-2, the major membrane protein in the secretory granule of the exocrine pancreas.
PubMed ID: 8666297
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 10760606
Title: Molecular cloning and sequences of cDNAs encoding alpha (large) and beta (small) isoforms of human pancreatic zymogen granule membrane-associated protein GP2.
PubMed ID: 10760606
PubMed ID: 19907495
Title: Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response.
PubMed ID: 19907495
DOI: 10.1038/nature08529
PubMed ID: 35273390
Title: Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
PubMed ID: 35273390
Sequence Information:
- Length: 537
- Mass: 59480
- Checksum: 8A6B6A0FC64F50B8
- Sequence:
MPHLMERMVG SGLLWLALVS CILTQASAVQ RGYGNPIEAS SYGLDLDCGA PGTPEAHVCF DPCQNYTLLD EPFRSTENSA GSQGCDKNMS GWYRFVGEGG VRMSETCVQV HRCQTDAPMW LNGTHPALGD GITNHTACAH WSGNCCFWKT EVLVKACPGG YHVYRLEGTP WCNLRYCTVP RDPSTVEDKC EKACRPEEEC LALNSTWGCF CRQDLNSSDV HSLQPQLDCG PREIKVKVDK CLLGGLGLGE EVIAYLRDPN CSSILQTEER NWVSVTSPVQ ASACRNILER NQTHAIYKNT LSLVNDFIIR DTILNINFQC AYPLDMKVSL QAALQPIVSS LNVSVDGNGE FIVRMALFQD QNYTNPYEGD AVELSVESVL YVGAILEQGD TSRFNLVLRN CYATPTEDKA DLVKYFIIRN SCSNQRDSTI HVEENGQSSE SRFSVQMFMF AGHYDLVFLH CEIHLCDSLN EQCQPSCSRS QVRSEVPAID LARVLDLGPI TRRGAQSPGV MNGTPSTAGF LVAWPMVLLT VLLAWLF
Genular Protein ID: 1716391081
Symbol: B7Z1G2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 515
- Mass: 57715
- Checksum: B3B3AF0CE347F616
- Sequence:
MKIKCEKSRT QSSAQHVQHS AHSTIVCRKH SHNAETAGRV DIVRGGPFFH HPLRKWLISP PLNKPSVWPR TPIIPVHQLR RDTWVGNCNK KTAHSRLHSH GWPEEERFVF SSELHGKSAY SKVTCMPHLM ERMVGSGLLW LALVSCILTQ ASAVQRVPRD PSTVEDKCEK ACRPEEECLA LNSTWGCFCR QDLNSSDVHS LQPQLDCGPR EIKVKVDKCL LGGLGLGEEV IAYLRDPNCS SILQTEERNW VSVTSPVQAS ACRNILERNQ THAIYKNTLS LVNDFIIRDT ILNINFQCAY PLDMKVSLQA ALQPIVSSLN VSVDGNGEFI VRMALFQDQN YTNPYEGDAV ELSVESVLYV GAILEQGDTS RFNLVLRNCY ATPTEDKADL VKYFIIRNSC SNQRDSTIHV EENGQSSESR FSVQMFMFAG HYDLVFLHCE IHLCDSLNEQ CQPSCSRSQV RSEVPAIDLA RVLDLGPITR RGAQSPGVMN GTPSTAGFLV AWPMVLLTVL LAWLF
Genular Protein ID: 1204423522
Symbol: Q68D34_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 530
- Mass: 58650
- Checksum: 5DDA60F600565F0D
- Sequence:
MERMVGSGLL WLALVSCILT QASAVQRGYG NPIEASSYGL DLDCGAPGTP EAHVCFDPCQ NYTLLDEPFR STENSAGSQG CDKNMSGWYR FVGEGGVRMS ETCVQVHRCQ TDAPMWLNGT HPALGDGITN HTACAHWSGN CCFWKTEVLV KACPGGYHVY RLEGTPWCNL RYCTDPSTVE DKCEKACRPE EECLALNSTW GCFCRQDLNS SDVHSLQPQL DCGPREIEVK VDKCLLGGLG LGEEVIAYLR DPNCSSILQT EERNWVSVTS PVQASACRNI LERNQTHAIY KNTLSLVNDF IIRDTILNIN FQCAYPLDMK VSLQAALQPI VSSLNVSVDG NGEFIVRMAL FQDQNYTNPY EGDAVELSVE SVLYVGAILE QGDTSRFNLV LRNCYATPTE DKADLVKYFI IRNSCSNQRD STIHVEENGQ SSESRFSVQM FMFAGHYDLV FLHCEIHLCD SLNEQCQPSC SRSQVRSEVP AIDLARVLDL GPITRRGAQS PGVMNGTPST AGFLVAWPMV LLTVLLAWLF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.