Details for: FLVCR1

Gene ID: 28982

Symbol: FLVCR1

Ensembl ID: ENSG00000162769

Description: FLVCR choline and heme transporter 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 133.6589
    Cell Significance Index: -20.7900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 79.7182
    Cell Significance Index: -20.2200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 51.7056
    Cell Significance Index: -21.3000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 47.4771
    Cell Significance Index: -22.4200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 45.0454
    Cell Significance Index: -18.3000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 17.5108
    Cell Significance Index: -21.5900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.0407
    Cell Significance Index: -21.5400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.6716
    Cell Significance Index: -17.4200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.5549
    Cell Significance Index: -21.9200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.6645
    Cell Significance Index: -8.0200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.6927
    Cell Significance Index: 335.9200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.2011
    Cell Significance Index: 32.1900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0673
    Cell Significance Index: 105.5800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9367
    Cell Significance Index: 845.7700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.9085
    Cell Significance Index: 50.9800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8843
    Cell Significance Index: 317.1900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.8529
    Cell Significance Index: 171.0900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.8328
    Cell Significance Index: 10.3300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.7132
    Cell Significance Index: 44.9500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5852
    Cell Significance Index: 63.6600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5673
    Cell Significance Index: 92.2600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5657
    Cell Significance Index: 33.9600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5197
    Cell Significance Index: 11.2600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.4113
    Cell Significance Index: 25.2800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.3732
    Cell Significance Index: 233.0400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3359
    Cell Significance Index: 63.9300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3129
    Cell Significance Index: 21.6400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3117
    Cell Significance Index: 8.7100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.3063
    Cell Significance Index: 7.3500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.2989
    Cell Significance Index: 20.1000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2771
    Cell Significance Index: 191.6300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2578
    Cell Significance Index: 46.4800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2546
    Cell Significance Index: 11.2600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2430
    Cell Significance Index: 9.2000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1925
    Cell Significance Index: 5.2400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1891
    Cell Significance Index: 4.1400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1757
    Cell Significance Index: 95.9600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1755
    Cell Significance Index: 6.1000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.1545
    Cell Significance Index: 4.4100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1335
    Cell Significance Index: 6.0500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1177
    Cell Significance Index: 14.4700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1052
    Cell Significance Index: 3.0300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0735
    Cell Significance Index: 32.5000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0709
    Cell Significance Index: 2.4900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0450
    Cell Significance Index: 84.6500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0432
    Cell Significance Index: 0.7400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0341
    Cell Significance Index: 46.3600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0329
    Cell Significance Index: 1.7300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0319
    Cell Significance Index: 49.1900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0284
    Cell Significance Index: 18.0600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0237
    Cell Significance Index: 4.0400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0218
    Cell Significance Index: 9.9100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0198
    Cell Significance Index: 36.5100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0157
    Cell Significance Index: 2.1600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0027
    Cell Significance Index: -0.3500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0070
    Cell Significance Index: -5.2200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0094
    Cell Significance Index: -0.7200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0140
    Cell Significance Index: -7.8700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0147
    Cell Significance Index: -2.1400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0198
    Cell Significance Index: -14.5200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0204
    Cell Significance Index: -15.4500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0352
    Cell Significance Index: -0.4200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0433
    Cell Significance Index: -9.1200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0474
    Cell Significance Index: -3.3500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0502
    Cell Significance Index: -0.5200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0580
    Cell Significance Index: -3.0200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0591
    Cell Significance Index: -7.6400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0620
    Cell Significance Index: -17.8500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0694
    Cell Significance Index: -8.0900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0709
    Cell Significance Index: -1.5100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1017
    Cell Significance Index: -2.1100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1021
    Cell Significance Index: -11.7000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1048
    Cell Significance Index: -10.7100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1192
    Cell Significance Index: -14.0600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1206
    Cell Significance Index: -5.6300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1288
    Cell Significance Index: -8.3100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1398
    Cell Significance Index: -10.4200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1424
    Cell Significance Index: -16.2500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1451
    Cell Significance Index: -6.8200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1460
    Cell Significance Index: -3.6500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1690
    Cell Significance Index: -17.6000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1814
    Cell Significance Index: -3.8500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1841
    Cell Significance Index: -11.2900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1993
    Cell Significance Index: -3.3400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2017
    Cell Significance Index: -4.0500
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.2382
    Cell Significance Index: -2.9700
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.2388
    Cell Significance Index: -2.0300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2523
    Cell Significance Index: -19.9800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2770
    Cell Significance Index: -7.1200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2863
    Cell Significance Index: -9.1700
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.2864
    Cell Significance Index: -4.0200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2890
    Cell Significance Index: -7.7300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3086
    Cell Significance Index: -9.8300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3094
    Cell Significance Index: -10.1300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3154
    Cell Significance Index: -16.4300
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.3407
    Cell Significance Index: -3.6200
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.3462
    Cell Significance Index: -4.3700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3499
    Cell Significance Index: -9.2000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3540
    Cell Significance Index: -7.0000
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.3677
    Cell Significance Index: -3.8300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** FLVCR1 is a transmembrane protein consisting of a large extracellular domain, a single transmembrane domain, and a small intracellular domain. The protein is composed of two functional domains: a choline transporter and a heme exporter. The choline transporter is responsible for transporting choline across the plasma membrane, while the heme exporter is involved in exporting heme from the cell. FLVCR1 is highly expressed in various cell types, including mural cells, neurons, and immune cells. **Pathways and Functions:** FLVCR1 is involved in several biological pathways, including: 1. **Heme biosynthesis:** FLVCR1 plays a crucial role in the export of heme from cells, which is essential for the production of hemoglobin and other heme-containing proteins. 2. **Iron homeostasis:** FLVCR1 helps regulate intracellular iron ion homeostasis by exporting heme, which is rich in iron, from cells. 3. **Immune function:** FLVCR1 is expressed in immune cells, such as dendritic cells and T cells, and is involved in the regulation of immune responses, including the presentation of antigens and the production of cytokines. 4. **Neurodevelopment:** FLVCR1 is expressed in neurons and is involved in the development and morphogenesis of the nervous system. 5. **Metabolism:** FLVCR1 is involved in the transport of choline, which is essential for the synthesis of phospholipids and other biomolecules. **Clinical Significance:** Dysregulation of FLVCR1 has been implicated in various diseases, including: 1. **Neurodegenerative disorders:** FLVCR1 has been linked to neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, due to its role in the transport of heme and its potential impact on iron metabolism. 2. **Immune disorders:** FLVCR1 has been implicated in immune disorders, such as multiple sclerosis and rheumatoid arthritis, due to its role in the regulation of immune responses. 3. **Cancer:** FLVCR1 has been identified as a potential target for cancer therapy, as it is overexpressed in certain types of cancer, including leukemia and lymphoma. In conclusion, FLVCR1 is a multifunctional protein that plays a crucial role in various biological processes, including immune function, development, and metabolism. Further research is needed to fully understand the mechanisms by which FLVCR1 regulates these processes and to explore its potential as a therapeutic target for various diseases. **References:** (No specific references provided, as this is a hypothetical review article. However, the information presented is based on the provided description of the FLVCR1 gene.)

Genular Protein ID: 3399188107

Symbol: FLVC1_HUMAN

Name: Feline leukemia virus subgroup C receptor-related protein 1

UniProtKB Accession Codes:

Q9Y5Y0 Q1HE16 Q86XY9 Q9NVR9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 10 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 EMDB 8 Ensembl 1 ExpressionAtlas 1 GO 25 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 Rhea 7 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10400745

Title: A putative cell surface receptor for anemia-inducing feline leukemia virus subgroup C is a member of a transporter superfamily.

PubMed ID: 10400745

DOI: 10.1128/jvi.73.8.6500-6505.1999

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11943475

Title: Genomic structure and evolutionary context of the human feline leukemia virus subgroup C receptor (hFLVCR) gene: evidence for block duplications and de novo gene formation within duplicons of the hFLVCR locus.

PubMed ID: 11943475

DOI: 10.1016/s0378-1119(02)00457-2

PubMed ID: 15369674

Title: Identification of a human heme exporter that is essential for erythropoiesis.

PubMed ID: 15369674

DOI: 10.1016/j.cell.2004.08.014

PubMed ID: 16439531

Title: Comprehensive mapping of receptor-functioning domains in feline leukemia virus subgroup C receptor FLVCR1.

PubMed ID: 16439531

DOI: 10.1128/jvi.80.4.1742-1751.2006

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20610401

Title: Kinetics and specificity of feline leukemia virus subgroup C receptor (FLVCR) export function and its dependence on hemopexin.

PubMed ID: 20610401

DOI: 10.1074/jbc.m110.119131

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23187127

Title: The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation.

PubMed ID: 23187127

DOI: 10.1172/jci62422

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 27923065

Title: Mutations in the heme exporter FLVCR1 cause sensory neurodegeneration with loss of pain perception.

PubMed ID: 27923065

DOI: 10.1371/journal.pgen.1006461

PubMed ID: 37100056

Title: Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals.

PubMed ID: 37100056

DOI: 10.1016/j.cmet.2023.04.003

PubMed ID: 38693265

Title: Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.

PubMed ID: 38693265

DOI: 10.1038/s41586-024-07374-4

PubMed ID: 38778100

Title: Molecular mechanism of choline and ethanolamine transport in humans.

PubMed ID: 38778100

DOI: 10.1038/s41586-024-07444-7

PubMed ID: 21070897

Title: Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa.

PubMed ID: 21070897

DOI: 10.1016/j.ajhg.2010.10.013

PubMed ID: 21267618

Title: Posterior column ataxia with retinitis pigmentosa in a Japanese family with a novel mutation in FLVCR1.

PubMed ID: 21267618

DOI: 10.1007/s10048-010-0271-4

PubMed ID: 22483575

Title: Mutations of FLVCR1 in posterior column ataxia and retinitis pigmentosa result in the loss of heme export activity.

PubMed ID: 22483575

DOI: 10.1016/j.bcmd.2012.03.004

PubMed ID: 28766925

Title: Posterior column ataxia with retinitis pigmentosa coexisting with sensory-autonomic neuropathy and leukemia due to the homozygous p.Pro221Ser FLVCR1 mutation.

PubMed ID: 28766925

DOI: 10.1002/ajmg.b.32570

PubMed ID: 30444160

Title: Clinical and imaging characteristics of posterior column ataxia with retinitis pigmentosa with a specific FLVCR1 mutation.

PubMed ID: 30444160

DOI: 10.1080/13816810.2018.1547913

Sequence Information:

  • Length: 555
  • Mass: 59863
  • Checksum: D0EBA9886CC8E747
  • Sequence:
    • MARPDDEEGA AVAPGHPLAK GYLPLPRGAP VGKESVELQN GPKAGTFPVN GAPRDSLAAA 
SGVLGGPQTP LAPEEETQAR LLPAGAGAET PGAESSPLPL TALSPRRFVV LLIFSLYSLV 
NAFQWIQYSI ISNVFEGFYG VTLLHIDWLS MVYMLAYVPL IFPATWLLDT RGLRLTALLG 
SGLNCLGAWI KCGSVQQHLF WVTMLGQCLC SVAQVFILGL PSRIASVWFG PKEVSTACAT 
AVLGNQLGTA VGFLLPPVLV PNTQNDTNLL ACNISTMFYG TSAVATLLFI LTAIAFKEKP 
RYPPSQAQAA LQDSPPEEYS YKKSIRNLFK NIPFVLLLIT YGIMTGAFYS VSTLLNQMIL 
TYYEGEEVNA GRIGLTLVVA GMVGSILCGL WLDYTKTYKQ TTLIVYILSF IGMVIFTFTL 
DLRYIIIVFV TGGVLGFFMT GYLPLGFEFA VEITYPESEG TSSGLLNASA QIFGILFTLA 
QGKLTSDYGP KAGNIFLCVW MFIGIILTAL IKSDLRRHNI NIGITNVDVK AIPADSPTDQ 
EPKTVMLSKQ SESAI

Genular Protein ID: 2484449379

Symbol: B2RB38_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2RB38

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 2 SUPFAM 1

Sequence Information:

  • Length: 555
  • Mass: 59919
  • Checksum: 6D9AA99751C8E742
  • Sequence:
    • MARPDDEEGA AVAPGHPLAK GYLPLPRGAP VGKESVELQN GPKAGTFPVN GPPRDSLAAA 
SGVLGGPQTP LAPEEETQAR LLPAGAGAET PGAESSPLPL TALSPRRFVV LLIFSLYSLV 
NAFQWIQYSI ISNVFEGFYG VTLLHIDWLS MVYMLAYVPL IFPATWLLDT RGLRLTALLG 
SGLNCLGAWI KCGSVQQHLF WVTMLGQCLC SVAQVFILGL PSRIASVWFG PKEVSTACAT 
AVLGNQLGTA VGFLLPPVLV PNTQNDTNLL ACNISTMFYG TSAVATLLFI LTAIAFKEKP 
RYPPSQAQAA LQDSPPEEYS YKKSIRNLFK NIPFVLLLIT YGIMTGAFYS VSTLLNQMIL 
TYYEGEEVNA GRIGLTLVVA GMVGSILCGL WLDYTKTYKQ TTLIVYILSF IGMVIFTFTL 
DLRYIIIVFV TGGVLGFFMT GYLPLGFEFA VEITYPESEG TSSGLLNASA QIFGILFTLA 
QGKLTSDYGP KAGNIFLCVW MFIGIILTAL IKSDLRRHNI NIGITNVDVK AIPADSPTDQ 
EPKMVMLSKQ SESAI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.