Details for: ANPEP

Gene ID: 290

Symbol: ANPEP

Ensembl ID: ENSG00000166825

Description: alanyl aminopeptidase, membrane

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 10.37
    Marker Score: 29,296
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 4.24
    Marker Score: 3,394
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 3.09
    Marker Score: 14,831
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 2.96
    Marker Score: 10,513
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 2.73
    Marker Score: 4,201
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 2.6
    Marker Score: 8,157
  • Cell Name: enterocyte of epithelium proper of ileum (CL1000342)
    Fold Change: 2.51
    Marker Score: 724
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 2.4
    Marker Score: 5,058
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 2.28
    Marker Score: 13,884
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.86
    Marker Score: 6,104
  • Cell Name: epithelial cell of exocrine pancreas (CL1001433)
    Fold Change: 1.85
    Marker Score: 1,040
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 1.76
    Marker Score: 877
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.75
    Marker Score: 97,814
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 1.66
    Marker Score: 417
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.6
    Marker Score: 1,070
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.58
    Marker Score: 391
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.56
    Marker Score: 3,668
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 1.51
    Marker Score: 1,727
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168,909
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.39
    Marker Score: 35,695
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 1.37
    Marker Score: 514
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.33
    Marker Score: 5,761
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.3
    Marker Score: 6,986
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.26
    Marker Score: 8,091
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.26
    Marker Score: 2,986
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.25
    Marker Score: 1,338
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 1.15
    Marker Score: 280
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.15
    Marker Score: 1,147
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.06
    Marker Score: 2,153
  • Cell Name: intestine goblet cell (CL0019031)
    Fold Change: 1.05
    Marker Score: 1,010
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.02
    Marker Score: 253
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,790
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,016
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,405
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 0.97
    Marker Score: 248
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.96
    Marker Score: 497
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.96
    Marker Score: 221
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.95
    Marker Score: 451
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,409
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.94
    Marker Score: 1,531
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 0.94
    Marker Score: 393
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5,346
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 0.93
    Marker Score: 1,817
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,739
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.91
    Marker Score: 948
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 0.91
    Marker Score: 424
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.9
    Marker Score: 1,036
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.88
    Marker Score: 317
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,296
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 0.8
    Marker Score: 2,310
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.79
    Marker Score: 539
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.79
    Marker Score: 223
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 0.78
    Marker Score: 335
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.77
    Marker Score: 592
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.77
    Marker Score: 380
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.76
    Marker Score: 304
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.75
    Marker Score: 386
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.73
    Marker Score: 467
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.72
    Marker Score: 3,039
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.72
    Marker Score: 1,279
  • Cell Name: M cell of gut (CL0000682)
    Fold Change: 0.72
    Marker Score: 186
  • Cell Name: glandular cell of esophagus (CL0002657)
    Fold Change: 0.71
    Marker Score: 225
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.7
    Marker Score: 642
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.7
    Marker Score: 5,211
  • Cell Name: monocyte (CL0000576)
    Fold Change: 0.7
    Marker Score: 906
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.7
    Marker Score: 260
  • Cell Name: type L enteroendocrine cell (CL0002279)
    Fold Change: 0.69
    Marker Score: 189
  • Cell Name: blood cell (CL0000081)
    Fold Change: 0.69
    Marker Score: 7,966
  • Cell Name: osteoblast (CL0000062)
    Fold Change: 0.68
    Marker Score: 365
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 174
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.66
    Marker Score: 467
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.65
    Marker Score: 189
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 0.65
    Marker Score: 147
  • Cell Name: club cell (CL0000158)
    Fold Change: 0.64
    Marker Score: 745
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.62
    Marker Score: 136
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 0.62
    Marker Score: 1,598
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.62
    Marker Score: 370
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.6
    Marker Score: 277
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.6
    Marker Score: 348
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.59
    Marker Score: 1,476
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 0.58
    Marker Score: 595
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.58
    Marker Score: 1,052
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.57
    Marker Score: 683
  • Cell Name: paneth cell (CL0000510)
    Fold Change: 0.56
    Marker Score: 388
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 0.55
    Marker Score: 315
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.55
    Marker Score: 439
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.55
    Marker Score: 881
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.54
    Marker Score: 18,501
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.54
    Marker Score: 264
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.53
    Marker Score: 8,225
  • Cell Name: tracheobronchial goblet cell (CL0019003)
    Fold Change: 0.53
    Marker Score: 144
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 0.52
    Marker Score: 134
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.51
    Marker Score: 190
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 0.51
    Marker Score: 141
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 0.51
    Marker Score: 187
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.49
    Marker Score: 205
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.49
    Marker Score: 531
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 0.49
    Marker Score: 299
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.48
    Marker Score: 137
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: 0.47
    Marker Score: 167

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure and Function:** ANPEP is a membrane-bound enzyme that belongs to the metalloaminopeptidase family. It possesses a zinc ion-binding site, which is essential for its catalytic activity. ANPEP is involved in the degradation of peptides and proteins, including angiotensinogen to angiotensins, and plays a role in various signaling pathways, including angiogenesis, cell differentiation, and immune system regulation. 2. **Expression Patterns:** ANPEP is significantly expressed in various cell types, including tracheal goblet cells, enterocytes, and epithelial cells of the proximal tubule, colon, and ileum. This widespread expression suggests that ANPEP plays a crucial role in maintaining tissue homeostasis and regulating cellular metabolism. 3. **Catalytic Activity:** ANPEP has a broad substrate specificity, degrading a wide range of peptides and proteins, including angiotensinogen, peptides, and proteins. This activity is essential for regulating various cellular processes, including metabolism, signaling, and immune response. **Pathways and Functions:** 1. **Angiogenesis:** ANPEP plays a role in angiogenesis, the process of new blood vessel formation, by degrading angiogenic peptides, such as vascular endothelial growth factor (VEGF). 2. **Cell Differentiation:** ANPEP is involved in cell differentiation, regulating the expression of genes involved in cell development and differentiation. 3. **Immune System Regulation:** ANPEP modulates the immune response by degrading peptides and proteins involved in immune signaling, such as angiotensinogen and angiotensin II. 4. **Metabolism of Angiotensinogen to Angiotensins:** ANPEP is essential for the degradation of angiotensinogen to angiotensins, which are key players in blood pressure regulation and electrolyte balance. 5. **Proteolysis and Peptide Catabolism:** ANPEP is involved in the degradation of peptides and proteins, regulating various cellular processes, including metabolism, signaling, and immune response. **Clinical Significance:** 1. **Diseases Associated with ANPEP Dysfunction:** Dysregulation of ANPEP has been implicated in various diseases, including hypertension, cardiovascular disease, and cancer. ANPEP dysfunction can lead to abnormal protein degradation, resulting in the accumulation of peptides and proteins that can contribute to disease pathology. 2. **Therapeutic Targeting of ANPEP:** ANPEP has been identified as a potential therapeutic target for the treatment of various diseases, including hypertension, cardiovascular disease, and cancer. Inhibitors of ANPEP have been developed, which can modulate its activity and regulate protein degradation. 3. **Implications for Immune Regulation:** ANPEP plays a crucial role in regulating the immune response, and dysregulation of ANPEP can lead to immune-related diseases, such as autoimmune disorders and cancer. In conclusion, ANPEP is a multifunctional enzyme that plays a critical role in immune regulation, cellular metabolism, and signaling pathways. Its dysregulation has been implicated in various diseases, and therapeutic targeting of ANPEP has shown promise in treating these conditions. Further research is needed to fully understand the role of ANPEP in human health and disease.

Genular Protein ID: 2417888377

Symbol: AMPN_HUMAN

Name: Alanyl aminopeptidase

UniProtKB Accession Codes:

P15144 Q16728 Q6GT90 Q8IUK3 Q8IVH3 Q9UCE0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTAC 2 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 DrugCentral 1 EC 1 EMBL 13 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 19 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 18 PDBsum 12 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 SABIO-RK 1 SAM 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2901990

Title: Complete amino acid sequence of human intestinal aminopeptidase N as deduced from cloned cDNA.

PubMed ID: 2901990

DOI: 10.1016/0014-5793(88)80502-7

PubMed ID: 2564851

Title: Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N.

PubMed ID: 2564851

DOI: 10.1172/jci114015

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1675638

Title: Separate promoters control transcription of the human aminopeptidase N gene in myeloid and intestinal epithelial cells.

PubMed ID: 1675638

DOI: 10.1016/s0021-9258(18)99056-3

PubMed ID: 7576235

Title: Identification of an alanine aminopeptidase in human maternal serum as a membrane-bound aminopeptidase N.

PubMed ID: 7576235

DOI: 10.1515/bchm3.1995.376.7.397

PubMed ID: 8102610

Title: Cholesterol crystallization-promoting activity of aminopeptidase-N isolated from the vesicular carrier of biliary lipids.

PubMed ID: 8102610

DOI: 10.1016/0014-5793(93)80199-5

PubMed ID: 6149934

Title: Purification and characterization of aminopeptidase N from human plasma.

PubMed ID: 6149934

DOI: 10.1159/000469453

PubMed ID: 1705556

Title: Variable O-glycosylation of CD13 (aminopeptidase N).

PubMed ID: 1705556

DOI: 10.1016/s0021-9258(20)64364-2

PubMed ID: 1350662

Title: Human aminopeptidase N is a receptor for human coronavirus 229E.

PubMed ID: 1350662

DOI: 10.1038/357420a0

PubMed ID: 7902291

Title: CD13 (GP150; aminopeptidase-N): predominant functional activity in blood is localized to plasma and is not cell-surface associated.

PubMed ID: 7902291

PubMed ID: 8105105

Title: CD13 (human aminopeptidase N) mediates human cytomegalovirus infection.

PubMed ID: 8105105

DOI: 10.1128/jvi.67.11.6576-6585.1993

PubMed ID: 8887485

Title: Characterization of functional domains in the human coronavirus HCV 229E receptor.

PubMed ID: 8887485

DOI: 10.1099/0022-1317-77-10-2515

PubMed ID: 9056417

Title: Defectively N-glycosylated and non-O-glycosylated aminopeptidase N (CD13) is normally expressed at the cell surface and has full enzymatic activity.

PubMed ID: 9056417

DOI: 10.1006/excr.1996.3455

PubMed ID: 9367365

Title: Identification of residues critical for the human coronavirus 229E receptor function of human aminopeptidase N.

PubMed ID: 9367365

DOI: 10.1099/0022-1317-78-11-2795

PubMed ID: 10605003

Title: Modification of the amino terminus of a class II epitope confers resistance to degradation by CD13 on dendritic cells and enhances presentation to T cells.

PubMed ID: 10605003

DOI: 10.4049/jimmunol.164.1.129

PubMed ID: 10676659

Title: Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis.

PubMed ID: 10676659

PubMed ID: 11384645

Title: Expression of aminopeptidase N in human endometrium and regulation of its activity by estrogen.

PubMed ID: 11384645

DOI: 10.1016/s0015-0282(01)01779-4

PubMed ID: 11559807

Title: Molecular determinants of species specificity in the coronavirus receptor aminopeptidase N (CD13): influence of N-linked glycosylation.

PubMed ID: 11559807

DOI: 10.1128/jvi.75.20.9741-9752.2001

PubMed ID: 12473585

Title: Soluble aminopeptidase N/CD13 in malignant and nonmalignant effusions and intratumoral fluid.

PubMed ID: 12473585

PubMed ID: 12551991

Title: Identification of a receptor-binding domain of the spike glycoprotein of human coronavirus HCoV-229E.

PubMed ID: 12551991

DOI: 10.1128/jvi.77.4.2530-2538.2003

PubMed ID: 15084671

Title: A proteomic analysis of human bile.

PubMed ID: 15084671

DOI: 10.1074/mcp.m400015-mcp200

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 22932899

Title: The X-ray crystal structure of human aminopeptidase N reveals a novel dimer and the basis for peptide processing.

PubMed ID: 22932899

DOI: 10.1074/jbc.m112.398842

PubMed ID: 9452074

Title: Identification of point mutations in the aminopeptidase N gene by SSCP analysis and sequencing.

PubMed ID: 9452074

DOI: 10.1002/humu.1380110153

Sequence Information:

  • Length: 967
  • Mass: 109540
  • Checksum: 37B6BC1BF0D6B1F2
  • Sequence:
    • MAKGFYISKS LGILGILLGV AAVCTIIALS VVYSQEKNKN ANSSPVASTT PSASATTNPA 
SATTLDQSKA WNRYRLPNTL KPDSYRVTLR PYLTPNDRGL YVFKGSSTVR FTCKEATDVI 
IIHSKKLNYT LSQGHRVVLR GVGGSQPPDI DKTELVEPTE YLVVHLKGSL VKDSQYEMDS 
EFEGELADDL AGFYRSEYME GNVRKVVATT QMQAADARKS FPCFDEPAMK AEFNITLIHP 
KDLTALSNML PKGPSTPLPE DPNWNVTEFH TTPKMSTYLL AFIVSEFDYV EKQASNGVLI 
RIWARPSAIA AGHGDYALNV TGPILNFFAG HYDTPYPLPK SDQIGLPDFN AGAMENWGLV 
TYRENSLLFD PLSSSSSNKE RVVTVIAHEL AHQWFGNLVT IEWWNDLWLN EGFASYVEYL 
GADYAEPTWN LKDLMVLNDV YRVMAVDALA SSHPLSTPAS EINTPAQISE LFDAISYSKG 
ASVLRMLSSF LSEDVFKQGL ASYLHTFAYQ NTIYLNLWDH LQEAVNNRSI QLPTTVRDIM 
NRWTLQMGFP VITVDTSTGT LSQEHFLLDP DSNVTRPSEF NYVWIVPITS IRDGRQQQDY 
WLIDVRAQND LFSTSGNEWV LLNLNVTGYY RVNYDEENWR KIQTQLQRDH SAIPVINRAQ 
IINDAFNLAS AHKVPVTLAL NNTLFLIEER QYMPWEAALS SLSYFKLMFD RSEVYGPMKN 
YLKKQVTPLF IHFRNNTNNW REIPENLMDQ YSEVNAISTA CSNGVPECEE MVSGLFKQWM 
ENPNNNPIHP NLRSTVYCNA IAQGGEEEWD FAWEQFRNAT LVNEADKLRA ALACSKELWI 
LNRYLSYTLN PDLIRKQDAT STIISITNNV IGQGLVWDFV QSNWKKLFND YGGGSFSFSN 
LIQAVTRRFS TEYELQQLEQ FKKDNEETGF GSGTRALEQA LEKTKANIKW VKENKEVVLQ 
WFTENSK

Genular Protein ID: 2975395160

Symbol: Q59E93_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59E93

Database IDs:

ARBA 15 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 4 DNASU 1 EMBL 2 GO 5 Gene3D 4 Genevisible 1 GenomeRNAi 1 InterPro 7 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 3 PRINTS 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 2

Sequence Information:

  • Length: 977
  • Mass: 110593
  • Checksum: 92DDAF01C7BBAAC3
  • Sequence:
    • GSLSRLPTIT MAKGFYISKS LGILGILLGV AAVCTIIALS VVYSQEKNKN ANSSPVASTT 
PSASATTNPA SATTLDQSKA WNRYRLPNTL KPDSYRVTLR PYLTPNDRGL YVFKGSSTVR 
FTCKEATDVI IIHSKKLNYT LSQGHRVVLR GVGGSQPPDI DKTELVEPTE YLVVHLKGSL 
VKDSQYEMDS EFEGELADDL AGFYRSEYME GNVRKVVATT QMQAADARKS FPCFDEPAMK 
AEFNITLIHP KDLTALSNML PKGPSTPLPE DPNWNVTEFH TTPKMSTYLL AFIVSEFDYV 
EKQASNGVLI RIWARPSAIA AGHGDYALNV TGPILNFFAG HYDTPYPLPK SDQIGLPDFN 
AGAMENWGLV TYRENSLLFD PLSSSSSNKE RVVTVIAHEL AHQWFGNLVT IEWWNDLWLN 
EGFASYVEYL GADYAEPTWN LKDLMVLNDV YRVMAVDALA SSHPLSTPAS EINTPAQISE 
LFDAISYSKG ASVLRMLSSF LSEDVFKQGL ASYLHTFAYQ NTIYLNLWDH LQEAVNNRSI 
QLPTTVRDIM NRWTLQMGFP VITVDTSTGT LSQEHFLLDP DSNVTRPSEF NYVWIVPITS 
IRDGRQQQDY WLIDVRAQND LFSTSGNEWV LLNLNVTGYY RVNYDEENWR KIQTQLQRDH 
SAIPVINRAQ IINDAFNLAS AHKVPVTLAL NNTLFLIEER QYMPWEAALS SLSYFKLMFD 
RSEVYGPMKN YLKKQVTPLF IHFRNNTNNW REIPENLMDQ YNEVNAISTA CSNGVPECEE 
MVSGLFKQWM ENPNNNPIHP NLRSTVYCNA IAQGGEEEWD FAWEQFRNAT LVNEADKLRA 
ALACSKELWI LNRYLSYTLN PDLIRKQDAT STIISITNNV IGQGLVWDFV QSNWKKLFND 
YGGGSFSFSN LIQAVTRRFS TEYELQQLEQ FKKDNEETGF GSGTRALEQA LEKTKANIKW 
VKENKEVVLQ WFTENSK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.