Details for: STXBP6
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 55.96rCSI 72.14%PRS 60.55
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CSI 32.59rCSI 40.54%PRS 57.27
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CSI 32.49rCSI 27.13%PRS 79.15
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CSI 24.5rCSI 39.4%PRS 61.12
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CSI 23.77rCSI 28.81%PRS 59.04
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CSI 22.45rCSI 70.23%PRS 63.53
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CSI 20.65rCSI 44.8%PRS 65.26
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CSI 18.48rCSI 33.87%PRS 82.46
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CSI 17.82rCSI 67.34%PRS 59.9
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CSI 17.62rCSI 25.29%PRS 67.4
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CSI 15.62rCSI 37.97%PRS 57.43
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CSI 14.26rCSI 24.66%PRS 68.86
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CSI 13.72rCSI 10.16%PRS 70.93
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CSI 13.37rCSI 19.58%PRS 72.03
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CSI 12.62rCSI 25.61%PRS 55.98
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CSI 10.86rCSI 53.51%PRS 85.6
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CSI 10.04rCSI 11.64%PRS 79.66
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CSI 9.49rCSI 7.5%PRS 65.91
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CSI 9.35rCSI 15.7%PRS 59.4
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CSI 9.19rCSI 20.14%PRS 83.57
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CSI 9.1rCSI 17.35%PRS 87.55
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CSI 9.03rCSI 11.23%PRS 78.99
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CSI 8.47rCSI 9.79%PRS 69.96
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CSI 8.46rCSI 34.48%PRS 69.82
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CSI 8.2rCSI 11.99%PRS 82.42
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CSI 8.08rCSI 14.32%PRS 47.31
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CSI 7.92rCSI 66.62%PRS 66.16
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CSI 7.6rCSI 9.75%PRS 73.85
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CSI 7.5rCSI 7.83%PRS 76.9
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CSI 7.08rCSI 14.98%PRS 89.4
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CSI 7rCSI 12.36%PRS 58.61
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CSI 6.45rCSI 22.1%PRS 64.25
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CSI 6.19rCSI 14.29%PRS 65.58
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CSI 6.18rCSI 5.95%PRS 70.51
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CSI 6rCSI 7.71%PRS 67.99
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CSI 5.92rCSI 13.51%PRS 69.07
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CSI 5.78rCSI 5.56%PRS 76.85
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CSI 5.57rCSI 24.5%PRS 66.18
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CSI 5.54rCSI 7.57%PRS 77.88
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CSI 5.15rCSI 4.57%PRS 75.4
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CSI 5.12rCSI 29.36%PRS 82.19
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CSI 5.11rCSI 4.29%PRS 80.59
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CSI 5.06rCSI 11.35%PRS 60.15
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CSI 4.92rCSI 9.29%PRS 85.96
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CSI 4.86rCSI 15.65%PRS 74.6
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CSI 4.85rCSI 7.72%PRS 70.42
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CSI 4.78rCSI 4.32%PRS 75.81
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CSI 4.56rCSI 4.78%PRS 81.14
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CSI 4.55rCSI 6.31%PRS 75.11
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CSI 4.45rCSI 11.61%PRS 78.57
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CSI 4.27rCSI 5.02%PRS 79.37
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CSI 4.26rCSI 8.84%PRS 74.35
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CSI 4.18rCSI 5.7%PRS 44.8
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CSI 3.91rCSI 4.67%PRS 59.37
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CSI 3.8rCSI 3.59%PRS 76.46
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CSI 3.74rCSI 8.22%PRS 81.42
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CSI 3.68rCSI 7.56%PRS 65.35
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CSI 3.67rCSI 27%PRS 64.73
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CSI 3.64rCSI 8%PRS 86.29
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CSI 3.55rCSI 12.79%PRS 57.34
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CSI 3.43rCSI 7.08%PRS 75.41
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CSI 3.29rCSI 4.65%PRS 77.55
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CSI 3.28rCSI 18.91%PRS 74.53
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CSI 3.27rCSI 4.64%PRS 74.35
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CSI 3.24rCSI 8.03%PRS 77.14
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CSI 3.18rCSI 17.1%PRS 85.56
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CSI 3.17rCSI 4.31%PRS 86.4
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CSI 3.13rCSI 3.27%PRS 75.22
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CSI 3.05rCSI 7.32%PRS 82.44
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CSI 2.98rCSI 14.25%PRS 77.62
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CSI 2.97rCSI 4.54%PRS 85.11
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CSI 2.86rCSI 68.37%PRS 57.82
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CSI 2.84rCSI 68.45%PRS 58.37
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CSI 2.8rCSI 6.05%PRS 83.99
-
CSI 2.68rCSI 4.27%PRS 81.3
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CSI 2.55rCSI 27.71%PRS 86.37
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CSI 2.4rCSI 14.14%PRS 60.22
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CSI 2.4rCSI 11.48%PRS 74.4
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CSI 2.39rCSI 3.78%PRS 79.33
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CSI 2.38rCSI 3.52%PRS 82.07
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CSI 2.32rCSI 9.06%PRS 55.76
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CSI 2.3rCSI 6.67%PRS 66.94
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CSI 2.3rCSI 9.27%PRS 77.17
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CSI 2.29rCSI 2.37%PRS 81.97
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CSI 2.19rCSI 3.98%PRS 68.99
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CSI 2.18rCSI 3.12%PRS 78.7
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CSI 2.14rCSI 5%PRS 88.68
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CSI 2.13rCSI 3.38%PRS 86.68
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CSI 2.07rCSI 6.94%PRS 61.71
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CSI 2rCSI 3.89%PRS 80.78
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CSI 1.97rCSI 7.84%PRS 85.79
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CSI 1.94rCSI 2.96%PRS 81.59
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CSI 1.9rCSI 4.55%PRS 82.09
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CSI 1.87rCSI 4.45%PRS 83.49
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CSI 1.81rCSI 3.18%PRS 71.03
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CSI 1.8rCSI 2.64%PRS 87.11
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CSI 1.76rCSI 6.6%PRS 69.93
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CSI 1.74rCSI 33.52%PRS 86.15
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CSI 1.68rCSI 4.5%PRS 69.08
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CSI 1.67rCSI 4.83%PRS 77.3
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CSI 0.2rCSI 2.2%PRS 83.5%
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CSI 0.2rCSI 3.8%PRS 94.0%
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CSI 0.3rCSI 4.4%PRS 86.6%
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CSI 0.6rCSI 3.2%PRS 86.6%
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CSI 0.7rCSI 1.9%PRS 72.6%
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CSI 0.7rCSI 2.5%PRS 82.2%
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CSI 0.7rCSI 3.3%PRS 87.3%
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CSI 0.7rCSI 5.3%PRS 71.2%
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CSI 0.8rCSI 3.7%PRS 86.4%
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CSI 0.9rCSI 6.2%PRS 84.8%
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CSI 1.0rCSI 6.8%PRS 76.2%
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CSI 1.0rCSI 5.0%PRS 83.8%
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CSI 1.0rCSI 7.6%PRS 86.3%
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CSI 1.1rCSI 4.6%PRS 85.2%
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CSI 1.2rCSI 3.1%PRS 71.0%
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CSI 1.2rCSI 1.8%PRS 86.4%
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CSI 1.2rCSI 1.3%PRS 83.0%
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CSI 1.2rCSI 2.8%PRS 84.2%
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CSI 1.2rCSI 3.2%PRS 72.9%
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CSI 1.2rCSI 3.2%PRS 79.0%
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CSI 1.3rCSI 3.4%PRS 82.9%
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CSI 1.3rCSI 3.1%PRS 70.2%
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CSI 1.3rCSI 3.2%PRS 81.3%
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CSI 1.4rCSI 3.2%PRS 64.5%
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CSI 1.4rCSI 3.0%PRS 63.3%
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CSI 1.4rCSI 1.8%PRS 81.0%
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CSI 1.4rCSI 12.3%PRS 65.3%
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CSI 1.5rCSI 15.4%PRS 71.6%
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CSI 1.5rCSI 8.7%PRS 63.4%
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CSI 1.6rCSI 4.3%PRS 85.4%
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CSI 1.6rCSI 4.1%PRS 85.3%
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CSI 1.6rCSI 1.7%PRS 74.9%
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CSI 1.6rCSI 2.6%PRS 44.8%
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CSI 1.6rCSI 2.5%PRS 77.9%
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CSI 1.6rCSI 10.1%PRS 69.3%
-
CSI 1.6rCSI 2.2%PRS 83.3%
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CSI 1.7rCSI 4.8%PRS 77.3%
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CSI 1.7rCSI 4.5%PRS 69.1%
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CSI 1.7rCSI 33.5%PRS 86.2%
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CSI 1.8rCSI 6.6%PRS 69.9%
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CSI 1.8rCSI 2.6%PRS 87.1%
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CSI 1.8rCSI 3.2%PRS 71.0%
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CSI 1.9rCSI 4.5%PRS 83.5%
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CSI 1.9rCSI 4.6%PRS 82.1%
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CSI 1.9rCSI 3.0%PRS 81.6%
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CSI 2.0rCSI 7.8%PRS 85.8%
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CSI 2.0rCSI 3.9%PRS 80.8%
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CSI 2.1rCSI 6.9%PRS 61.7%
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CSI 2.1rCSI 3.4%PRS 86.7%
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CSI 2.1rCSI 5.0%PRS 88.7%
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CSI 2.2rCSI 3.1%PRS 78.7%
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CSI 2.2rCSI 4.0%PRS 69.0%
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CSI 2.3rCSI 2.4%PRS 82.0%
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CSI 2.3rCSI 9.3%PRS 77.2%
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CSI 2.3rCSI 6.7%PRS 66.9%
-
CSI 2.3rCSI 9.1%PRS 55.8%
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CSI 2.4rCSI 3.5%PRS 82.1%
-
CSI 2.4rCSI 3.8%PRS 79.3%
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CSI 2.4rCSI 11.5%PRS 74.4%
-
CSI 2.4rCSI 14.1%PRS 60.2%
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CSI 2.6rCSI 27.7%PRS 86.4%
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CSI 2.7rCSI 4.3%PRS 81.3%
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CSI 2.8rCSI 6.1%PRS 84.0%
-
CSI 2.8rCSI 68.5%PRS 58.4%
-
CSI 2.9rCSI 68.4%PRS 57.8%
-
CSI 3.0rCSI 4.5%PRS 85.1%
-
CSI 3.0rCSI 14.3%PRS 77.6%
-
CSI 3.1rCSI 7.3%PRS 82.4%
-
CSI 3.1rCSI 3.3%PRS 75.2%
-
CSI 3.2rCSI 4.3%PRS 86.4%
-
CSI 3.2rCSI 17.1%PRS 85.6%
-
CSI 3.2rCSI 8.0%PRS 77.1%
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CSI 3.3rCSI 4.6%PRS 74.4%
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CSI 3.3rCSI 18.9%PRS 74.5%
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CSI 3.3rCSI 4.7%PRS 77.6%
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CSI 3.4rCSI 7.1%PRS 75.4%
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CSI 3.6rCSI 12.8%PRS 57.3%
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CSI 3.6rCSI 8.0%PRS 86.3%
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CSI 3.7rCSI 27.0%PRS 64.7%
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CSI 3.7rCSI 7.6%PRS 65.4%
-
CSI 3.7rCSI 8.2%PRS 81.4%
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CSI 3.8rCSI 3.6%PRS 76.5%
-
CSI 3.9rCSI 4.7%PRS 59.4%
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CSI 4.2rCSI 5.7%PRS 44.8%
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CSI 4.3rCSI 8.8%PRS 74.4%
-
CSI 4.3rCSI 5.0%PRS 79.4%
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CSI 4.5rCSI 11.6%PRS 78.6%
-
CSI 4.6rCSI 6.3%PRS 75.1%
-
CSI 4.6rCSI 4.8%PRS 81.1%
-
CSI 4.8rCSI 4.3%PRS 75.8%
-
CSI 4.9rCSI 7.7%PRS 70.4%
-
CSI 4.9rCSI 15.7%PRS 74.6%
-
CSI 4.9rCSI 9.3%PRS 86.0%
-
CSI 5.1rCSI 11.4%PRS 60.2%
-
CSI 5.1rCSI 4.3%PRS 80.6%
-
CSI 5.1rCSI 29.4%PRS 82.2%
-
CSI 5.2rCSI 4.6%PRS 75.4%
-
CSI 5.5rCSI 7.6%PRS 77.9%
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CSI 5.6rCSI 24.5%PRS 66.2%
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CSI 5.8rCSI 5.6%PRS 76.9%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 3253204239
Symbol: STXB6_HUMAN
Name: Syntaxin-binding protein 6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12145319
Title: Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly.
PubMed ID: 12145319
PubMed ID: 11042152
Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.
PubMed ID: 11042152
DOI: 10.1101/gr.140200
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
Sequence Information:
- Length: 210
- Mass: 23554
- Checksum: 7C046A90D4C4B2D8
- Sequence:
MSAKSAISKE IFAPLDERML GAVQVKRRTK KKIPFLATGG QGEYLTYICL SVTNKKPTQA SITKVKQFEG STSFVRRSQW MLEQLRQVNG IDPNGDSAEF DLLFENAFDQ WVASTASEKC TFFQILHHTC QRYLTDRKPE FINCQSKIMG GNSILHSAAD SVTSAVQKAS QALNERGERL GRAEEKTEDL KNSAQQFAET AHKLAMKHKC