Details for: BRF1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.47
Marker Score: 3,471 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.41
Marker Score: 2,870 - Cell Name: neuron (CL0000540)
Fold Change: 1.33
Marker Score: 5,416 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.33
Marker Score: 50,459 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.31
Marker Score: 12,347 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.31
Marker Score: 12,400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.3
Marker Score: 79,791 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.28
Marker Score: 4,965 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.28
Marker Score: 401 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.27
Marker Score: 10,949 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.27
Marker Score: 19,898 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.26
Marker Score: 12,977 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.23
Marker Score: 18,343 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.22
Marker Score: 45,056 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.21
Marker Score: 9,308 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.19
Marker Score: 383 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.19
Marker Score: 1,831 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.17
Marker Score: 23,347 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.12
Marker Score: 672 - Cell Name: germ cell (CL0000586)
Fold Change: 1.06
Marker Score: 1,844 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.05
Marker Score: 4,363 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,742 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,966 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,400 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.97
Marker Score: 1,070 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,404 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 483 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 437 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,717 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.88
Marker Score: 5,290 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,294 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.87
Marker Score: 4,946 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 308 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.85
Marker Score: 18,151 - Cell Name: interneuron (CL0000099)
Fold Change: 0.84
Marker Score: 382 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.81
Marker Score: 973 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,265 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.78
Marker Score: 326 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.77
Marker Score: 453 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.76
Marker Score: 580 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.76
Marker Score: 361 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.74
Marker Score: 1,774 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.72
Marker Score: 291 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 0.72
Marker Score: 265 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 375 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.7
Marker Score: 342 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.7
Marker Score: 222 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.7
Marker Score: 2,928 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.7
Marker Score: 2,921 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.7
Marker Score: 537 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.68
Marker Score: 395 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.68
Marker Score: 198 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.68
Marker Score: 818 - Cell Name: brush cell (CL0002204)
Fold Change: 0.67
Marker Score: 615 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.67
Marker Score: 3,107 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.66
Marker Score: 170 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.65
Marker Score: 169 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.65
Marker Score: 748 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.65
Marker Score: 1,425 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.64
Marker Score: 634 - Cell Name: fat cell (CL0000136)
Fold Change: 0.62
Marker Score: 345 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.61
Marker Score: 168 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.61
Marker Score: 1,032 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.61
Marker Score: 654 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.6
Marker Score: 2,072 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.6
Marker Score: 807 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 0.59
Marker Score: 186 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.58
Marker Score: 1,111 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.57
Marker Score: 1,406 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.57
Marker Score: 493 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.57
Marker Score: 318 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.56
Marker Score: 216 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.56
Marker Score: 247 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.55
Marker Score: 18,629 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.55
Marker Score: 2,029 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.54
Marker Score: 765 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.54
Marker Score: 356 - Cell Name: podocyte (CL0000653)
Fold Change: 0.54
Marker Score: 198 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.54
Marker Score: 427 - Cell Name: basal cell (CL0000646)
Fold Change: 0.53
Marker Score: 686 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 0.53
Marker Score: 4,587 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 0.53
Marker Score: 358 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.52
Marker Score: 345 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.52
Marker Score: 354 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.51
Marker Score: 578 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.51
Marker Score: 147 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.51
Marker Score: 575 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 0.51
Marker Score: 133 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.5
Marker Score: 539 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.5
Marker Score: 459 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.49
Marker Score: 295 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.49
Marker Score: 156 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.49
Marker Score: 4,296 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.49
Marker Score: 198 - Cell Name: acinar cell (CL0000622)
Fold Change: 0.48
Marker Score: 341 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.48
Marker Score: 7,730 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.48
Marker Score: 690 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.47
Marker Score: 233 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.47
Marker Score: 191 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.47
Marker Score: 450
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3702656121
Symbol: TF3B_HUMAN
Name: Transcription factor IIIB 90 kDa subunit
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7624363
Title: Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains.
PubMed ID: 7624363
PubMed ID: 8943358
Title: RNA polymerase III transcription from the human U6 and adenovirus type 2 VAI promoters has different requirements for human BRF, a subunit of human TFIIIB.
PubMed ID: 8943358
PubMed ID: 10921893
Title: Alternatively spliced hBRF variants function at different RNA polymerase III promoters.
PubMed ID: 10921893
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14592981
Title: TFIIIB is phosphorylated, disrupted and selectively released from tRNA promoters during mitosis in vivo.
PubMed ID: 14592981
DOI: 10.1093/emboj/cdg544
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18377933
Title: Regulation of RNA polymerase III transcription by Maf1 in mammalian cells.
PubMed ID: 18377933
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25561519
Title: BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies.
PubMed ID: 25561519
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 677
- Mass: 73840
- Checksum: 5866304B879EC1DE
- Sequence:
MTGRVCRGCG GTDIELDAAR GDAVCTACGS VLEDNIIVSE VQFVESSGGG SSAVGQFVSL DGAGKTPTLG GGFHVNLGKE SRAQTLQNGR RHIHHLGNQL QLNQHCLDTA FNFFKMAVSR HLTRGRKMAH VIAACLYLVC RTEGTPHMLL DLSDLLQVNV YVLGKTFLLL ARELCINAPA IDPCLYIPRF AHLLEFGEKN HEVSMTALRL LQRMKRDWMH TGRRPSGLCG AALLVAARMH DFRRTVKEVI SVVKVCESTL RKRLTEFEDT PTSQLTIDEF MKIDLEEECD PPSYTAGQRK LRMKQLEQVL SKKLEEVEGE ISSYQDAIEI ELENSRPKAK GGLASLAKDG STEDTASSLC GEEDTEDEEL EAAASHLNKD LYRELLGGAP GSSEAAGSPE WGGRPPALGS LLDPLPTAAS LGISDSIREC ISSQSSDPKD ASGDGELDLS GIDDLEIDRY ILNESEARVK AELWMRENAE YLREQREKEA RIAKEKELGI YKEHKPKKSC KRREPIQAST AREAIEKMLE QKKISSKINY SVLRGLSSAG GGSPHREDAQ PEHSASARKL SRRRTPASRS GADPVTSVGK RLRPLVSTQP AKKVATGEAL LPSSPTLGAE PARPQAVLVE SGPVSYHADE EADEEEPDEE DGEPCVSALQ MMGSNDYGCD GDEDDGY
Genular Protein ID: 889167371
Symbol: V9HVY2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 208
- Mass: 22309
- Checksum: 8761AE32A65FFE89
- Sequence:
MTGRVCRGCG GTDIELDAAR GDAVCTACGS VLEDNIIVSE VQFVESSGGG SSAVGQFVSL DGAGKTPTLG GGFHVNLGKE SRAQTLQNGR RHIHHLGNQL QLNQHCLDTA FNFFKMAVSR HLTRGRKMAH VIAACLYLVC RTEGTPHMLL DLSDLLQVDS LRPASFPTWG CDLGVVTRVV TGVYPRCLHA SQWPVCAACP VRKFWSVG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.