Details for: BRF1

Gene ID: 2972

Symbol: BRF1

Ensembl ID: ENSG00000185024

Description: BRF1 general transcription factor IIIB subunit

Associated with

  • Gene expression (transcription)
    (R-HSA-74160)
  • Rna polymerase iii abortive and retractive initiation
    (R-HSA-749476)
  • Rna polymerase iii transcription
    (R-HSA-74158)
  • Rna polymerase iii transcription initiation
    (R-HSA-76046)
  • Rna polymerase iii transcription initiation from type 1 promoter
    (R-HSA-76061)
  • Rna polymerase iii transcription initiation from type 2 promoter
    (R-HSA-76066)
  • Dna-templated transcription initiation
    (GO:0006352)
  • Metal ion binding
    (GO:0046872)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase iii
    (GO:0045945)
  • Protein binding
    (GO:0005515)
  • Rna polymerase iii general transcription initiation factor activity
    (GO:0000995)
  • Rna polymerase iii type 3 promoter sequence-specific dna binding
    (GO:0001006)
  • Rrna transcription
    (GO:0009303)
  • Tbp-class protein binding
    (GO:0017025)
  • Transcription by rna polymerase iii
    (GO:0006383)
  • Transcription factor tfiiib complex
    (GO:0000126)
  • Transcription initiation at rna polymerase iii promoter
    (GO:0006384)
  • Transcription preinitiation complex
    (GO:0097550)
  • Transcription preinitiation complex assembly
    (GO:0070897)
  • Trna transcription
    (GO:0009304)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 150.0850
    Cell Significance Index: -23.3500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 88.7466
    Cell Significance Index: -22.5100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 52.2851
    Cell Significance Index: -24.6900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 47.6299
    Cell Significance Index: -19.3500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 20.3458
    Cell Significance Index: -19.4300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 19.4573
    Cell Significance Index: -23.9900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.5036
    Cell Significance Index: -22.7800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.1200
    Cell Significance Index: -24.1500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.0883
    Cell Significance Index: -18.7000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.5052
    Cell Significance Index: -9.8600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.6193
    Cell Significance Index: 308.1600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0871
    Cell Significance Index: 218.0800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.9779
    Cell Significance Index: 28.1800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8610
    Cell Significance Index: 777.3800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7270
    Cell Significance Index: 144.2700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7250
    Cell Significance Index: 32.8600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6921
    Cell Significance Index: 248.2600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6072
    Cell Significance Index: 98.7600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5304
    Cell Significance Index: 11.4900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4388
    Cell Significance Index: 51.1400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4258
    Cell Significance Index: 11.9000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3856
    Cell Significance Index: 23.1500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.3576
    Cell Significance Index: 7.8300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3286
    Cell Significance Index: 17.0700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.3186
    Cell Significance Index: 8.1900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.3047
    Cell Significance Index: 17.1000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2981
    Cell Significance Index: 206.1700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2931
    Cell Significance Index: 15.2700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2869
    Cell Significance Index: 22.0200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2808
    Cell Significance Index: 12.4200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2506
    Cell Significance Index: 9.4900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2472
    Cell Significance Index: 6.1800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2439
    Cell Significance Index: 43.9800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2392
    Cell Significance Index: 16.5500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2048
    Cell Significance Index: 7.2000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1676
    Cell Significance Index: 10.8200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1624
    Cell Significance Index: 19.9700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1224
    Cell Significance Index: 16.8100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1137
    Cell Significance Index: 62.1200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0956
    Cell Significance Index: 42.2700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0727
    Cell Significance Index: 4.8900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0720
    Cell Significance Index: 7.1200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0613
    Cell Significance Index: 3.8700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0586
    Cell Significance Index: 2.7300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0514
    Cell Significance Index: 0.7700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0432
    Cell Significance Index: 0.7400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0429
    Cell Significance Index: 80.8400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0303
    Cell Significance Index: 46.6900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0277
    Cell Significance Index: 17.6000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0244
    Cell Significance Index: 44.9400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0129
    Cell Significance Index: 17.5900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0079
    Cell Significance Index: 3.5700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0047
    Cell Significance Index: 0.1000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0005
    Cell Significance Index: -0.0900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0074
    Cell Significance Index: -0.9500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0157
    Cell Significance Index: -0.4200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0210
    Cell Significance Index: -15.3700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0272
    Cell Significance Index: -20.6000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0273
    Cell Significance Index: -20.2200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0278
    Cell Significance Index: -4.0400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0402
    Cell Significance Index: -22.6500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0429
    Cell Significance Index: -26.7700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0448
    Cell Significance Index: -0.7500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0676
    Cell Significance Index: -19.4500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0807
    Cell Significance Index: -8.2400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0829
    Cell Significance Index: -10.7100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0985
    Cell Significance Index: -11.2900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1031
    Cell Significance Index: -12.1600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1056
    Cell Significance Index: -2.1900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1072
    Cell Significance Index: -5.6300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1101
    Cell Significance Index: -5.1800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1246
    Cell Significance Index: -26.2500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1323
    Cell Significance Index: -1.9000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1463
    Cell Significance Index: -4.1800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1746
    Cell Significance Index: -12.3500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1770
    Cell Significance Index: -13.1900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1844
    Cell Significance Index: -5.0200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1897
    Cell Significance Index: -19.7500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2075
    Cell Significance Index: -7.2100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2120
    Cell Significance Index: -6.7900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2269
    Cell Significance Index: -6.0800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2625
    Cell Significance Index: -20.7900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2812
    Cell Significance Index: -5.4900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3200
    Cell Significance Index: -19.6200
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: -0.3262
    Cell Significance Index: -1.4200
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.3285
    Cell Significance Index: -5.2700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3385
    Cell Significance Index: -8.9000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3400
    Cell Significance Index: -20.9000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3733
    Cell Significance Index: -4.4500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3863
    Cell Significance Index: -5.2700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4273
    Cell Significance Index: -12.2500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.4281
    Cell Significance Index: -9.1500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4528
    Cell Significance Index: -14.4200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.4577
    Cell Significance Index: -4.2200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4715
    Cell Significance Index: -9.8700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4731
    Cell Significance Index: -15.4900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.4760
    Cell Significance Index: -12.1600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.5110
    Cell Significance Index: -7.7000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.5195
    Cell Significance Index: -7.6700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.5324
    Cell Significance Index: -15.6800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Subunit of RNA polymerase III transcription initiation factor**: BRF1 is a subunit of the RNA polymerase III transcription initiation factor complex, which is essential for the initiation of transcription by RNA polymerase III. 2. **Positive regulation of transcription**: BRF1 enhances the transcriptional activity of RNA polymerase III by facilitating the assembly of the preinitiation complex. 3. **Specific binding to DNA**: BRF1 binds to specific DNA sequences, including type 1 and type 2 promoters, which are recognized by RNA polymerase III. 4. **Metal ion binding**: BRF1 contains metal ion-binding domains, which are essential for its function and stability. 5. **Cell-specific expression**: BRF1 is expressed in various cell types, including kidney proximal straight tubule epithelial cells, immature innate lymphoid cells, neurons, and other cell types. **Pathways and Functions** 1. **Dna-templated transcription initiation**: BRF1 plays a crucial role in the initiation of transcription by RNA polymerase III, which involves the unwinding of DNA and the assembly of the preinitiation complex. 2. **Gene expression (transcription)**: BRF1 regulates the expression of a wide range of genes, including those involved in ribosomal RNA synthesis, tRNA production, and the expression of certain small nuclear RNAs and microRNAs. 3. **RNA polymerase III abortive and retractive initiation**: BRF1 is involved in the regulation of RNA polymerase III abortive and retractive initiation, which is a process that regulates the termination of transcription. 4. **Positive regulation of transcription by RNA polymerase III**: BRF1 enhances the transcriptional activity of RNA polymerase III, which is essential for the expression of certain genes. **Clinical Significance** 1. **Disorders of RNA polymerase III**: Mutations in the BRF1 gene have been associated with disorders of RNA polymerase III, which can lead to developmental abnormalities and other clinical manifestations. 2. **Cancer**: BRF1 has been implicated in the regulation of gene expression in cancer cells, and its dysregulation has been associated with tumorigenesis. 3. **Neurological disorders**: BRF1 has been implicated in the regulation of gene expression in the nervous system, and its dysregulation has been associated with neurological disorders, such as autism and schizophrenia. 4. **Kidney disease**: BRF1 has been implicated in the regulation of gene expression in the kidney, and its dysregulation has been associated with kidney disease. In conclusion, the BRF1 gene plays a crucial role in the regulation of gene expression by facilitating the initiation of transcription by RNA polymerase III. Its dysregulation has been associated with various disorders, including cancer, neurological disorders, and kidney disease. Further research is needed to fully understand the role of BRF1 in human disease and to develop therapeutic strategies for the treatment of BRF1-related disorders.

Genular Protein ID: 3702656121

Symbol: TF3B_HUMAN

Name: Transcription factor IIIB 90 kDa subunit

UniProtKB Accession Codes:

Q92994 B3KU36 B4DIG5 B7Z2N3 F5H5Z7 F8WA46 Q13223 Q3SYD9 Q5PR24 Q6IQ02 Q96KX3 Q9HCW6 Q9HCW7 Q9HCW8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 7 CDD 2 CORUM 1 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 15 Ensembl 7 ExpressionAtlas 1 GO 15 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 8 Pumba 1 RNAct 1 Reactome 3 RefSeq 8 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7624363

Title: Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains.

PubMed ID: 7624363

DOI: 10.1073/pnas.92.15.7026

PubMed ID: 8943358

Title: RNA polymerase III transcription from the human U6 and adenovirus type 2 VAI promoters has different requirements for human BRF, a subunit of human TFIIIB.

PubMed ID: 8943358

DOI: 10.1128/mcb.16.12.7031

PubMed ID: 10921893

Title: Alternatively spliced hBRF variants function at different RNA polymerase III promoters.

PubMed ID: 10921893

DOI: 10.1093/emboj/19.15.4134

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14592981

Title: TFIIIB is phosphorylated, disrupted and selectively released from tRNA promoters during mitosis in vivo.

PubMed ID: 14592981

DOI: 10.1093/emboj/cdg544

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18377933

Title: Regulation of RNA polymerase III transcription by Maf1 in mammalian cells.

PubMed ID: 18377933

DOI: 10.1016/j.jmb.2008.02.060

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25561519

Title: BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies.

PubMed ID: 25561519

DOI: 10.1101/gr.176925.114

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 677
  • Mass: 73840
  • Checksum: 5866304B879EC1DE
  • Sequence:
    • MTGRVCRGCG GTDIELDAAR GDAVCTACGS VLEDNIIVSE VQFVESSGGG SSAVGQFVSL 
DGAGKTPTLG GGFHVNLGKE SRAQTLQNGR RHIHHLGNQL QLNQHCLDTA FNFFKMAVSR 
HLTRGRKMAH VIAACLYLVC RTEGTPHMLL DLSDLLQVNV YVLGKTFLLL ARELCINAPA 
IDPCLYIPRF AHLLEFGEKN HEVSMTALRL LQRMKRDWMH TGRRPSGLCG AALLVAARMH 
DFRRTVKEVI SVVKVCESTL RKRLTEFEDT PTSQLTIDEF MKIDLEEECD PPSYTAGQRK 
LRMKQLEQVL SKKLEEVEGE ISSYQDAIEI ELENSRPKAK GGLASLAKDG STEDTASSLC 
GEEDTEDEEL EAAASHLNKD LYRELLGGAP GSSEAAGSPE WGGRPPALGS LLDPLPTAAS 
LGISDSIREC ISSQSSDPKD ASGDGELDLS GIDDLEIDRY ILNESEARVK AELWMRENAE 
YLREQREKEA RIAKEKELGI YKEHKPKKSC KRREPIQAST AREAIEKMLE QKKISSKINY 
SVLRGLSSAG GGSPHREDAQ PEHSASARKL SRRRTPASRS GADPVTSVGK RLRPLVSTQP 
AKKVATGEAL LPSSPTLGAE PARPQAVLVE SGPVSYHADE EADEEEPDEE DGEPCVSALQ 
MMGSNDYGCD GDEDDGY

Genular Protein ID: 889167371

Symbol: V9HVY2_HUMAN

Name: N/A

UniProtKB Accession Codes:

V9HVY2

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 ExpressionAtlas 1 GO 7 Gene3D 2 HOGENOM 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 Pfam 2 RefSeq 1 SMART 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Sequence Information:

  • Length: 208
  • Mass: 22309
  • Checksum: 8761AE32A65FFE89
  • Sequence:
    • MTGRVCRGCG GTDIELDAAR GDAVCTACGS VLEDNIIVSE VQFVESSGGG SSAVGQFVSL 
DGAGKTPTLG GGFHVNLGKE SRAQTLQNGR RHIHHLGNQL QLNQHCLDTA FNFFKMAVSR 
HLTRGRKMAH VIAACLYLVC RTEGTPHMLL DLSDLLQVDS LRPASFPTWG CDLGVVTRVV 
TGVYPRCLHA SQWPVCAACP VRKFWSVG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.