Details for: GUCA1B
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 50.3391
Cell Significance Index: -7.8300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 31.0081
Cell Significance Index: -7.8700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 10.8692
Cell Significance Index: 685.0500 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.1675
Cell Significance Index: 16.6200 - Cell Name: retinal cone cell (CL0000573)
Fold Change: 0.5980
Cell Significance Index: 7.4700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.3991
Cell Significance Index: 5.4500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.2342
Cell Significance Index: 6.0200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2149
Cell Significance Index: 43.1000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.1351
Cell Significance Index: 1.6100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1152
Cell Significance Index: 21.9300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1137
Cell Significance Index: 40.7800 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.0776
Cell Significance Index: 1.7000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.0610
Cell Significance Index: 17.5600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.0553
Cell Significance Index: 3.3200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0527
Cell Significance Index: 7.6600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0462
Cell Significance Index: 2.5900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0458
Cell Significance Index: 1.3200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0425
Cell Significance Index: 1.1400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0400
Cell Significance Index: 7.9300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0335
Cell Significance Index: 2.5700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0275
Cell Significance Index: 3.5300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0249
Cell Significance Index: 4.4900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0229
Cell Significance Index: 1.0400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.0127
Cell Significance Index: 11.4900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0080
Cell Significance Index: 0.2800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0078
Cell Significance Index: 0.1700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0066
Cell Significance Index: 12.3600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0066
Cell Significance Index: 10.1400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0053
Cell Significance Index: 0.5800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0029
Cell Significance Index: 5.3900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0016
Cell Significance Index: 1.0400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0013
Cell Significance Index: 1.7400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0029
Cell Significance Index: -0.0500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0032
Cell Significance Index: -1.4400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.0080
Cell Significance Index: -1.3100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0082
Cell Significance Index: -6.0700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0087
Cell Significance Index: -3.8400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0089
Cell Significance Index: -0.8900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0095
Cell Significance Index: -7.0000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0099
Cell Significance Index: -0.4400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0101
Cell Significance Index: -7.6800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0112
Cell Significance Index: -6.3200 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0119
Cell Significance Index: -6.4900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0209
Cell Significance Index: -0.7900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0216
Cell Significance Index: -1.4600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0223
Cell Significance Index: -1.3700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0224
Cell Significance Index: -2.7600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0228
Cell Significance Index: -3.8900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0264
Cell Significance Index: -0.6600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0314
Cell Significance Index: -6.6200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0330
Cell Significance Index: -2.2800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0416
Cell Significance Index: -5.7100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0425
Cell Significance Index: -2.2100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0429
Cell Significance Index: -5.0000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0437
Cell Significance Index: -3.0900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0447
Cell Significance Index: -2.7500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0454
Cell Significance Index: -5.2100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0555
Cell Significance Index: -1.5500 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0573
Cell Significance Index: -7.4000 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.0610
Cell Significance Index: -1.5200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0639
Cell Significance Index: -1.7400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0647
Cell Significance Index: -7.6300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0668
Cell Significance Index: -6.8200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0683
Cell Significance Index: -7.1100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0719
Cell Significance Index: -3.3500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0750
Cell Significance Index: -3.7900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0771
Cell Significance Index: -1.6000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0806
Cell Significance Index: -2.5800 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0840
Cell Significance Index: -1.6400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0885
Cell Significance Index: -7.0100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0939
Cell Significance Index: -7.0000 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0941
Cell Significance Index: -4.0900 - Cell Name: hepatocyte (CL0000182)
Fold Change: -0.0973
Cell Significance Index: -1.3500 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.0989
Cell Significance Index: -1.6300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1062
Cell Significance Index: -4.9900 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.1135
Cell Significance Index: -1.6100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1153
Cell Significance Index: -7.4400 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.1203
Cell Significance Index: -2.0800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1225
Cell Significance Index: -6.4300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1227
Cell Significance Index: -6.3900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1350
Cell Significance Index: -4.3000 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1357
Cell Significance Index: -2.8800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1445
Cell Significance Index: -4.7300 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1453
Cell Significance Index: -3.8800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1459
Cell Significance Index: -5.1100 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.1470
Cell Significance Index: -2.1700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1689
Cell Significance Index: -4.8200 - Cell Name: Mueller cell (CL0000636)
Fold Change: -0.1703
Cell Significance Index: -1.3100 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1708
Cell Significance Index: -3.6900 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1728
Cell Significance Index: -3.4700 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1736
Cell Significance Index: -4.3300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1906
Cell Significance Index: -4.0600 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.1907
Cell Significance Index: -3.9800 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.1926
Cell Significance Index: -2.7600 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1997
Cell Significance Index: -4.1800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2035
Cell Significance Index: -4.8800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.2051
Cell Significance Index: -5.8800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.2076
Cell Significance Index: -3.0700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.2089
Cell Significance Index: -7.2600 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.2096
Cell Significance Index: -3.5300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 366487989
Symbol: GUC1B_HUMAN
Name: Guanylyl cyclase-activating protein 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9119368
Title: The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1).
PubMed ID: 9119368
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 9620085
Title: The localization of guanylyl cyclase-activating proteins in the mammalian retina.
PubMed ID: 9620085
PubMed ID: 10507726
Title: Genetic analysis of the guanylate cyclase activator 1B (GUCA1B) gene in patients with autosomal dominant retinal dystrophies.
PubMed ID: 10507726
PubMed ID: 15452722
Title: Mutations in the gene coding for guanylate cyclase-activating protein 2 (GUCA1B gene) in patients with autosomal dominant retinal dystrophies.
PubMed ID: 15452722
Sequence Information:
- Length: 200
- Mass: 23420
- Checksum: 79B898868BA35768
- Sequence:
MGQEFSWEEA EAAGEIDVAE LQEWYKKFVM ECPSGTLFMH EFKRFFKVTD DEEASQYVEG MFRAFDKNGD NTIDFLEYVA ALNLVLRGTL EHKLKWTFKI YDKDGNGCID RLELLNIVEG IYQLKKACRR ELQTEQGQLL TPEEVVDRIF LLVDENGDGQ LSLNEFVEGA RRDKWVMKML QMDMNPSSWL AQQRRKSAMF
Genular Protein ID: 4140771767
Symbol: Q7Z3V9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 200
- Mass: 23318
- Checksum: 7DA8DD918CD32729
- Sequence:
MGQEFSWEEA EAAGEIDVAE LQEWYKKFVM ECPSGTLFMH EFKRFFKVTD DEEASQYVEG MFRAFDKNGD NTIDFLEYVA ALNLVLRGTL EHKLKRTFKI YDKDGNGCID RLELLNIVEG IYQLKKACRR ELQTEQGQLL TPEEVVDRIF LLVDENGDGQ LSLNGFVEGA RRDKWVMKML QMDMNPSSWL AQQRRKSAMF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.